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Antibodies to Adhesion Molecules for Immunotherapy of Brain Tumors

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Brain Tumor Immunotherapy

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Abstract

The major morbidity of gliomas lies in their infiltrative growth. The cell biology of invading neoplastic cells is similar to that of migrating fetal cells. Several adhesion molecules that are downregulated after completion of fetal brain development are re-expressed in neoplasms of the nervous system. The crucial role played by adhesion molecules during neural development is repeated during glioma invasion (1).

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  1. S. Ather Enam MD PHD
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Editors and Affiliations

  1. School of Medicine, University of California at Los Angeles, CA, USA

    Linda M. Liau MD, PhD , Donald P. Becker MD  & Timothy F. Cloughesy MD ,  & 

  2. Department of Pathology and Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, NC, USA

    Darell D. Bigner MD, PhD

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Enam, S.A. (2001). Antibodies to Adhesion Molecules for Immunotherapy of Brain Tumors. In: Liau, L.M., Becker, D.P., Cloughesy, T.F., Bigner, D.D. (eds) Brain Tumor Immunotherapy. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-035-3_12

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  • DOI: https://doi.org/10.1007/978-1-59259-035-3_12

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