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Regulation of the Melanocortin Receptors by Agouti

  • William O. Wilkison
Chapter
Part of the The Receptors book series (REC)

Abstract

The melanocortin family of receptors has been implicated in the regulation of a number of physiologic systems. Despite the cloning and characterization of these receptors, little is known about their regulation. I will summarize in this chapter what is known about a novel regulator of melanocortin receptor activity, the agouti gene product. Not only does the action of agouti on these receptors explain or clarify the physiologic role of some of these receptors, agouti function and regulation also imparts new possibilities for these receptors having a role in processes such as energy homeostasis.

Keywords

Coat Color B16F10 Cell Melanocortin Receptor Agouti Gene Carboxyl Terminal Region 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2000

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  • William O. Wilkison

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