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Drug—Food Interactions

  • Kevin W. Garey
  • Keith A. Rodvold
Part of the Infectious Disease book series (ID)

Abstract

Drug—food interactions can be a major source of patient inconvenience and nonadherence through disruptions in a patient’s daily schedule. Unless advised to the contrary, patients often take drugs with meals as a suitable adherence reminder and to lessen gastrointestinal side effects. Lack of knowledge of potentially significant drug—food interactions can lead to poor clinical outcomes. This chapter will describe mechanisms of drug—food interactions and U.S. Food and Drug Administration (FDA) guidelines for drug—food interactions studies. Antimicrobial drug—food interactions based on drug classes and pharmacokinetics will be described, as well as the recommended dosing guidelines. In addition, anti-infectives and the disulfiram-like reaction and two case studies are included.

Keywords

Human Immunodeficiency Virus Antimicrob Agent Empty Stomach Oral Cephalosporin Cefpodoxime Proxetil 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Kevin W. Garey
  • Keith A. Rodvold

There are no affiliations available

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