Abstract
Abnormalities of blood lipids constitute one of the more common risk factors for cardiovascular disease that coexist with systemic arterial hypertension (Table 33-1). Hypertension and lipid disturbances may be part of a genetic abnormality, the Familial Dyslipidemic Syndrome, which is found in approx 12% of people with hypertension and in approx 50% of those with early familial hypertension, increased LDL cholesterol, and triglycerides. Thus, it is often necessary to consider the additional cardiovascular risk associated with dyslipidemia when planning a therapeutic strategy for hypertensive patients.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Suggested Readings
Fuster V, Badimon L, et al. (1992) The pathogenesis of coronary artery disease and the acute coronary syndrome. N Engl J Med 326: 242–250.
Fuster V, et al. (1992) The pathogenesis of coronary artery disease and the acute coronary syndrome (second of two parts). N Engl J Med 326: 310–318.
Giles TD (1997) Lipid factors in the hypertension syndrome. J Cardiovasc Risk 4: 257–259.
Grundy SM (1995) Role of low-density lipoproteins in atherogenesis and development of coronary heart disease. Clin Chem 41: 139–146.
Malloy MJ, Kane JP (1998) Aggressive medical therapy for the prevention and treatment of coronary artery disease. Disease-A-Month 44: 1–40.
Reaven GM, Lithell H, Landsberg L (1996) Hypertension and associated metabolic abnormalities—the role of insulin resistance and the sympathoadrenal system. NEngl J Med 334: 374–381.
Scandinavian Simvastatin Survival Study Group (1994) Randomised trial of cholesterol lowering in 4444 patients with Coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344: 1383–1389.
Shepard J, Cobbe SM, Ford I, et al. (1995) Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 333: 1301–1307.
Stary HC (1989) Evolution and progression of astherosclerotic lesions in coronary arteries of children and young adults. Arteriosclerosis 9: 119–132.
Williams RR, Hunt SC, Hopkins PN, Stults BM, Wu LL, Hasstedt SJ (1988) Familial dyslipidemic hypertension: evidence from 58 Utah families for a syndrome present in approximately 12% of patients with essential hypertension. JAMA 259: 3579–3596.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer Science+Business Media New York
About this chapter
Cite this chapter
Giles, T.D. (2001). Lipid Abnormalities and Hypertension. In: Weber, M.A. (eds) Hypertension Medicine. Current Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-008-7_33
Download citation
DOI: https://doi.org/10.1007/978-1-59259-008-7_33
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-4757-5446-9
Online ISBN: 978-1-59259-008-7
eBook Packages: Springer Book Archive