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Principles and Practice of Transplant Infectious Diseases pp 249–263Cite as

Intravascular Catheter and Implantable Device Infections in Transplant Patients

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Abstract

The use of intravascular devices for administration of drugs, fluids, blood products, and nutritional support is essential in patients undergoing transplantation procedures. These intravascular devices have a significant potential to produce iatrogenic disease, such as bloodstream infection originating from colonization of the indwelling intravascular devices. Over two-thirds of all healthcare-associated bacteremia originate from devices used for vascular access. Patients undergoing hematopoietic stem cell transplantation, who have inherently compromised immune function because of their cancer and are further incapacitated due to the preparatory pretransplant conditioning regimen or graft-versus-host disease, are particularly prone to device-related infections. In this chapter, a comprehensive review of epidemiology, disease pathogenesis, clinical presentation, treatment, and prevention of intravascular device-related infections is presented.

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Authors and Affiliations

  1. Section of Infectious Diseases, Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public Health, and the William S. Middleton Memorial Veterans Hospital, Madison, WI, USA

    Nasia Safdar & Dennis G. Maki

  2. Section of Infectious Diseases, Department of Medicine, University of the Philippines Manila, Philippine General Hospital, Manila, Philippines

    Cybele Lara R. Abad

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  1. Nasia Safdar
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  2. Cybele Lara R. Abad
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  3. Dennis G. Maki
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Correspondence to Nasia Safdar .

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  1. Clinical Associate Professor of Medicine, Texas Tech University Health Sciences Center El Paso, Paul L. Foster School of Medicine, El Paso, TX, USA

    Amar Safdar

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Safdar, N., Abad, C.L.R., Maki, D.G. (2019). Intravascular Catheter and Implantable Device Infections in Transplant Patients. In: Safdar, A. (eds) Principles and Practice of Transplant Infectious Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-9034-4_13

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