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Cardiovascular Magnetic Resonance Imaging pp 99–112Cite as

Techniques for MR Myocardial Perfusion Imaging

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Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

Outside the field of MRI, most techniques for myocardial perfusion imaging rely on the detection of injected tracers to assess myocardial blood flow and detect ischemia. Examples are tracers that emit gamma rays for single-photon emission tomography or tracers that scatter ultrasound waves, such as injected gas-filled bubbles. With MRI, blood-borne contrast agents can be used to assess myocardial perfusion. The presence of the contrast agent in tissue is detected through its effects on the local T1 and T2 relaxation times of 1H nuclei. An alternative approach for assessing myocardial perfusion without using an exogenous contrast agent relies on selectively “labeling” 1H spins and detecting the signal changes that are induced by tissue blood flow carrying “labeled” 1H spins in or out of an image slice. Though the absence on contrast agents makes arterial spin labeling an attractive proposition, its use is limited by the relatively small signal changes that need to be detected for quantifying myocardial perfusion. This chapter will focus foremost on contrast-enhanced perfusion imaging, as it remains the most widely used approach for myocardial perfusion imaging.

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Author information

Authors and Affiliations

  1. Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Michael Jerosch-Herold

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  1. Michael Jerosch-Herold
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Correspondence to Michael Jerosch-Herold .

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Editors and Affiliations

  1. Cardiovascular Division, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA

    Raymond Y. Kwong

  2. Department of Radiology, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA

    Michael Jerosch-Herold

  3. Department of Cardiac Sciences, University of Calgary, Calgary, AB, Canada

    Bobak Heydari

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Jerosch-Herold, M. (2019). Techniques for MR Myocardial Perfusion Imaging. In: Kwong, R., Jerosch-Herold, M., Heydari, B. (eds) Cardiovascular Magnetic Resonance Imaging. Contemporary Cardiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-8841-9_6

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  • DOI: https://doi.org/10.1007/978-1-4939-8841-9_6

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