Post-therapy Marrow Changes

  • Jason H. KurzerEmail author
  • Olga K. Weinberg
Part of the Atlas of Anatomic Pathology book series (AAP)


Bone marrow biopsies and aspirates from patients undergoing various forms of treatment can show a variety of histological and cytological findings, and it is therefore imperative that pathologists understand the array of associated therapy-related effects. Patients receiving induction chemotherapy for acute leukemia frequently have bone marrow aspirates and/or biopsies at specific intervals, allowing the pathologist to observe the immediate and long-term effects of the treatment regimen (Table 3.1).


Myeloablative therapy Growth factor therapy Post-ATRA findings Tyrosine kinase inhibitor Rituximab 


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© Springer Science+Business Media, LLC 2018

Authors and Affiliations

  1. 1.Stanford University School of MedicineStanfordUSA
  2. 2.Pathology DepartmentBoston Children’s HospitalBostonUSA

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