Skip to main content

Proximal Femur Nonunions

  • Chapter
  • First Online:
Book cover Nonunions
  • 1007 Accesses

Abstract

Hip fractures in adults are common among the elderly with low-energy falls but also occur in younger patients with high-energy mechanisms. Most of these fractures are treated surgically generally proceeding to union when surgery is performed correctly. In the proximal femur, the femoral neck is most prone to nonunion but occurs in the intertrochanteric and subtrochanteric regions as well. The surgeon should suspect nonunion if there is persistent pain in the region or loss of reduction. Varus deformity should particularly be scrutinized. Hardware failure is typically associated with nonunion. In addition to radiographs, CT scans can be useful to define the nonunion. The nonunion should then be analyzed for contributing factors. Not only should mechanical factors be taken into account, but also biologic factors both local and systemic should also be assessed to generate a treatment plan. Revision surgery may entail alternate fixation, bone graft, osteotomy, arthroplasty, or resection. The strategy chosen depends on nonunion location, causative factors, and patient needs. In the femoral neck, the valgus intertrochanteric osteotomy corrects varus and has a high success rate. It is technically demanding but somewhat less than a vascularized fibula, which has been advocated for nonunions with avascular necrosis. Arthroplasty has gained popularity in the older patient as a treatment for nonunion but is associated with lower success rates compared to primary arthroplasty. Intertrochanteric and subtrochanteric nonunions although uncommon are successfully treated with revision fixation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Cornwall R, Gilbert MS, Koval KJ, Strauss E, Siu AL. Functional outcomes and mortality vary among different types of hip fractures: a function of patient characteristics. Clin Orthop Relat Res. 2004;425:64–71.

    Article  Google Scholar 

  2. Morshed S. Current options for determining fracture union. Adv Med. 2014, Article ID 708574. doi:9.1155/2014/708574.

    Google Scholar 

  3. Bhandari M, Chiavaras M, Ayeni O, Chakraverrty R, Parasu N, Choudur H, et al. Assessment group for radiographic evaluation and evidence (AGREE) Study Group (AGREE Investigators Writing Committee). Assessment of radiographic fracture healing in patients with operatively treated femoral neck fractures. J Orthop Trauma. 2013;27(9):e213–9.

    Article  PubMed  Google Scholar 

  4. Bhandari M, Chiavaras MM, Parasu N, Choudur H, Ayeni O, Chakravertty R, et al. Radiographic union score for hip substantially improves agreement between surgeons and radiologists. BMC Musculoskelet Disord. 2013;14:70.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Brinker MR, O’Connor D, Monla Y, Earthman TP. Metabolic and endocrine abnormalities in patients with nonunions. J Orthop Trauma. 2007;21(8):557–70.

    Article  PubMed  Google Scholar 

  6. Koval KJ, Maurer SG, Su ET, Aharonoff GB, Zuckerman JD. The effects of nutritional status on outcome after hip fracture. J Orthop Trauma. 1999;13(3):164–9.

    Article  CAS  PubMed  Google Scholar 

  7. Dodwell ER, Latorre JG, Parisini E, Zwettler E, Chandra D, Mulpuri K, Snyder B. NSAID exposure and risk of nonunion: a meta-analysis of case–control and cohort studies. Calcif Tissue Int. 2010;87(3):193–202.

    Article  CAS  PubMed  Google Scholar 

  8. Gerstenfeld LC, Thiede M, Seibert K, Mielke C, Phippard D, Svagr B, et al. Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs. J Orthop Res. 2003;21(4):670–5.

    Article  CAS  PubMed  Google Scholar 

  9. Matthews V, Cabanela ME. Femoral neck nonunion treatment. Clin Orthop. 2004;419:57–64.

    Article  Google Scholar 

  10. Blood T, Feller RJ, Cohen E, Born CT, Hayda R. Atypical fractures of the femur: evaluation and treatment. JBJS Reviews. 2015;3(3):e1–8.

    Article  Google Scholar 

  11. Nardi A, Ventura L, Cozzi L, Tonini G, Zennaro R, Celi M, Ramazzina E. The bone anabolic therapy. Aging Clin Exp Res. 2013;25(Suppl 1):S121–4.

    Article  PubMed  Google Scholar 

  12. Rubin LE, Murgo KT, Ritterman SA, McClure PK. Hip resection arthroplasty. JBJS Rev. 2014;2(5):e3.

    Article  Google Scholar 

  13. Protzman RR, Burkhalter WE. Femoral-neck fractures in young adults. J Bone Joint Surg Am. 1976;58(5):689–95.

    Article  CAS  PubMed  Google Scholar 

  14. Swiontkowski MF, Winquist RA, Hansen ST Jr. Fractures of the femoral neck in patients between the ages of twelve and forty-nine years. J Bone Joint Surg Am. 1984;66(6):837–46.

    Article  CAS  PubMed  Google Scholar 

  15. Angelini M, McKee MD, Waddell JP, Haidukewych G, Schemitsch EH. Salvage of failed hip fracture fixation. J Orthop Trauma. 2009;23(6):471–8.

    Article  PubMed  Google Scholar 

  16. Haidukewych GJ, Rothwell WS, Jacofsky DJ, Torchia ME, Berry DJ. Operative treatment of femoral neck fractures in patients between the ages of fifteen and fifty years. J Bone Joint Surg Am. 2004;86-A(8):1711–1716.

    Google Scholar 

  17. Parker MJ, Raghavan R, Gurusamy K. Incidence of fracture-healing complications after femoral neck fractures. Clin Orthop Relat Res. 2007;458:175–9.

    PubMed  Google Scholar 

  18. Conn KS, Parker MJ. Undisplaced intracapsular hip fractures: results of internal fixation in 375 patients. Clin Orthop Relat Res. 2004;421:249–54.

    Article  Google Scholar 

  19. Hitt K. Femoral neck nonunion: osteotomy or arthroplasty. Tech Orthop. 2001;17(4):434–42.

    Article  Google Scholar 

  20. Trueta J, Harrison MH. The normal vascular anatomy of the femoral head in adult man. J Bone Joint Surg Br. 1953;35-B(3):442–461.

    Google Scholar 

  21. Hughes PE, Hsu JC, Matava MJ. Hip anatomy and biomechanics in the athlete. Sports Med Arthrosc Rev. 2002;10(2):103–14.

    Article  Google Scholar 

  22. Alho A, Benterud JG, Solovieva S. Internally fixed femoral neck fractures: early preduction of failure in 203 elderly patients with displaced fractures. Acta Orthop Scand. 1999;70(2):141–4.

    Article  CAS  PubMed  Google Scholar 

  23. Bartonícek J. Pauwels’ classification of femoral neck fractures: correct interpretation of the original. J Orthop Trauma. 2001;15(5):358–360. Review.

    Google Scholar 

  24. Goldstein C, Petrisor BA, Ferguson T, Bhandari M. Implants for fixation of femoral neck fractures. Tech Orthop. 2008;23(4):301–8.

    Article  Google Scholar 

  25. Gurusamy, Parker MJ, Rowlands TK. The complications of displaced intracapsular fractures of the hip the effect of screw positioning and angulation on fracture healing. J Bone Joint Surg Br. 2005;87(5):632–634.

    Google Scholar 

  26. Marti RK, Schüller HM, Raaymakers EL. Intertrochanteric osteotomy for non-union of the femoral neck. J Bone Joint Surg Br. 1989;71(5):782–7.

    Article  CAS  PubMed  Google Scholar 

  27. Anglen JO. Intertrochanteric osteotomy for failed internal fixation of femoral neck fracture. Clin Orthop. 1997;341:175–82.

    Article  Google Scholar 

  28. Schoenfeld AJ, Vrabec GA. Valgus osteotomy of the proximal femur with sliding hip screw for the treatment of femoral neck nonunions: the technique, a case series, and literature review. J Orthop Trauma. 2006;20(7):485–91.

    Article  PubMed  Google Scholar 

  29. Hartford JM, Patel A, Powell J. Intertrochanteric osteotomy using a dynamichip screw for femoral neck nonunion. J Orthop Trauma. 2005;19(5):329–33.

    PubMed  Google Scholar 

  30. Said GZ, Farouk O, Said HG. Valgus intertrochanteric osteotomy with single-angled 130° plate fixation for fractures and non-unions of the femoral neck. Int Orthop. 2010;34(8):1291–5.

    Article  PubMed  Google Scholar 

  31. LeCroy CM, Rizzo M, Gunneson EE, Urbaniak JR. Free vascularized fibular bone grafting in the management of femoral neck nonunion in patients younger than fifty years. J Orthop Trauma. 2002;16(7):464–72.

    Article  PubMed  Google Scholar 

  32. Jun X, Chang-Qing Z, Kai-Gang Z, Hong-Shuai L, Jia-Gen S. Modified free vascularized fibular grafting for the treatment of femoral neck nonunion. J Orthop Trauma. 2010;24(4):230–5.

    Article  PubMed  Google Scholar 

  33. Elgafy H, Ebraheim NA, Bach HG. Revision internal fixation and nonvascular fibular graft for femoral neck nonunion. J Trauma. 2011;70(1):169–73.

    Article  PubMed  Google Scholar 

  34. Wu CC, Shih CH, Chen WJ, Tai CL. Treatment of femoral neck nonunions with a sliding compression screw: comparison with and without subtrochanteric valgus osteotomy. J Trauma. 1999;46(2):312–7.

    Article  CAS  PubMed  Google Scholar 

  35. Meyers MH, Harvey JP Jr, Moore TM. The muscle pedicle bone graft in the treatment of displaced fractures of the femoral neck: indications, operative technique and results. Orthop Clin North Am. 1974;5(4):779–92.

    CAS  PubMed  Google Scholar 

  36. Baksi DP. Internal fixation of ununited femoral neck fractures combined with muscle-pedicle bone grafting. J Bone Joint Surg Br. 1986;68(2):239–45.

    CAS  PubMed  Google Scholar 

  37. Ballmer FT, Ballmer PM, Baumgaertel F, Ganz R, Mast JW. Pauwels osteotomy for nonunions of the femoral neck. Orthop Clin North Am. 1990;21(4):759–67.

    CAS  PubMed  Google Scholar 

  38. Hou SM, Hang YS, Liu TK. Ununited femoral neck fractures by open reduction and vascularized iliac bone graft. Clin Orthop Relat Res. 1993;294:176–80.

    Google Scholar 

  39. Leung PC, Shen WY. Fracture of the femoral neck in younger adults: a new method of treatment of delayed and nonunions. Clin Orthop Relat Res. 1993;295:156–60.

    Google Scholar 

  40. Cordero-Ampuero J, de Dios M. What are the risk factors for infection in hemiarthroplasties and total hip arthroplasties? Clin Orthop Relat Res. 2010;468(12):3268–77.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Franzén H, Nilsson LT, Strömqvist B, Johnsson R, Herrlin K. Secondary total hip replacement after fractures of the femoral neck. J Bone Joint Surg Br. 1990;72(5):784–7.

    Article  PubMed  Google Scholar 

  42. Hägglund G, Nordström B, Lidgren L. Total hip replacement after nailing failure in femoral neck fractures. Arch OrthopTrauma Surg. 1984;103(2):125–7.

    Article  Google Scholar 

  43. Nilsson LT, Jalovaara P, Franzén H, Niinimäki T, Strömqvist B. Function after primary hemiarthroplasty and secondary total hip arthroplasty in femoral neck fracture. J Arthroplasty. 1994;9(4):369–73.

    Article  CAS  PubMed  Google Scholar 

  44. Tabsh I, Waddell JP, Morton J. Total hip arthroplasty for complications of proximal femoral fractures. J Orthop Trauma. 1997;11(3):166–9.

    Article  CAS  PubMed  Google Scholar 

  45. Turner A, Wroblewski BM. Charnley low-friction arthroplasty for the treatment of hips with late complications of femoral neck fractures. Clin Orthop. 1984;185:126–30.

    Google Scholar 

  46. Haidukewych G, Berry DJ. Salvage of failed treatment of hip fractures. J Am Acad Orthop Surg. 2005;13(2):101–9.

    Article  PubMed  Google Scholar 

  47. McKinley JC, Robinson CM. Treatment of displaced intracapsular hip fractures with total hip arthroplasty: comparison of primary arthroplasty with early salvage arthroplasty after failed internal fixation. J Bone Joint Surg Am. 2002; 84-A(11):2010–5.

    Google Scholar 

  48. Mabry TM, Prpa B, Haidukewych GJ, Harmsen WS, Berry DJ. Long-term results of total hip arthroplasty for femoral neck fracture nonunion. J Bone Joint Surg Am. 2004;86-A(10):2263–2267.

    Google Scholar 

  49. Ferguson GS, Cabanela ME, Ilstrup DM. Total hip arthoplasty after failed intertrochanteric osteotomy. J Bone Joint Surg Br. 199;76(2): 252–257.

    Google Scholar 

  50. Boos N, Krushell R, Ganz R, Müller ME. Total hip arthroplasty after previous proximal femoral osteotomy. J Bone Joint Surg Br. 1997;79(2):247–53.

    Article  CAS  PubMed  Google Scholar 

  51. Sandhu HS, Sandhu PS, Kapoor A. Neglected fractured neck of the femura predictive classification and treatment by osteosynthesis. Clin Orthop Relat Res. 2005;431:14–20.

    Article  Google Scholar 

  52. Nagi ON, Dhillon MS, Goni VG. Open reduction, internal fixation and fibular autografting for neglected fracture of the femoral neck. J Bone Joint Surg Br. 1998;80(5):798–804.

    Article  CAS  PubMed  Google Scholar 

  53. Huang HC. Treatment of neglected femoral neck fractures in young adults. Clin Orthop Relat Res. 1986;206(5):119–126.

    Google Scholar 

  54. Roshan A, Ram S. Early return to function in young adults with neglected femoral neck fractures. Clin Orthop Relat Res. 2006;447(6):152–7.

    Article  PubMed  Google Scholar 

  55. Lifeso R, Younge D. The neglected hip fracture. J Orthop Trauma. 1990;4(3):287–92.

    Article  CAS  PubMed  Google Scholar 

  56. Verghese VD, Boopalan PR, Titus V, Oomen VT, Jepegnanam TS. Indices affecting outcome following neglected femoral neck fracture after valus intertrochanteric osteotomy. J Orthop Trauma. 2014;28(7):410–6.

    Article  Google Scholar 

  57. Glassner PJ, Tejwani NC. Failure of proximal femoral locking compression plate: a case series. J Orthop Trauma. 2011;25(2):7683.

    Article  Google Scholar 

  58. Johnson B, Stevenson B, Chamma R, Patel A, Rhee S, Lever C, et al. Short-term follow-up of pertrochanteric fractures treated using the proximal femoral locking plate. J Orthop Trauma. 2014;28(5):283–7.

    Article  PubMed  Google Scholar 

  59. Haidukewych GJ, Berry DJ. Salvage of failed internal fixation of intertrochanteric hip fracture. Clin Orthop Relat Res. 2003;412:184–8.

    Article  Google Scholar 

  60. Mariani EM, Rand JA. Nonunion of intertrochanteric fractures of the femur following open reduction and internal fixation: Results of second attempts to gain union. Clin Orthop Relat Res. 1987;218:81–9.

    Google Scholar 

  61. Sarathy MP, Madhavan P, Ravichandran KM. Nonunion of intertrochanteric fractures of the femur. J Bone Joint Surg Br. 1995;77(1):90–2.

    CAS  PubMed  Google Scholar 

  62. Wu CC, Shih CH, Chen WJ, Tai CL. Treatment of cutout of a lag screw of a dynamic hip screw in an intertrochanteric fracture. Arch Orthop Trauma Surg. 1998;117(4–5):193–6.

    Article  CAS  PubMed  Google Scholar 

  63. Bartonícek J, Skála-Rosenbaum J, Dousa P. Valgus intertrochanteric osteotomy for malunion and nonunion of trochanteric fractures. J Orthop Trauma. 2003;17(6):606–12.

    Article  PubMed  Google Scholar 

  64. Haidukewych GJ, Berry DJ. Hip arthroplasty for salvage of failed treatment of intertrochanteric hip fractures. J Bone Joint Surg Am. 2003;85-A(5):899–904.

    Google Scholar 

  65. Hammad A, Abdel-aal A, Said HG, Bakr H. Total hip arthroplasty following failure of dynamic hip screw fixation of fractures of the proximal femur. Acta Orthop Belg. 2008;74(6):788–92.

    PubMed  Google Scholar 

  66. Laffosse JM, Molinier F, Tricoire JL, Bonnevialle N, Chiron P, Puget J. Salvage hip arthroplasty for trochanteric osteosynthesis failure in the elderly. Acta Orthop Belg. 2007;73(6):729–36.

    PubMed  Google Scholar 

  67. Tabsh I, Waddell JP, Morton J. Total hip arthroplasty forcomplications of proximal femoral fractures. J Orthop Trauma. 1997;11(3):166–9.

    Article  CAS  PubMed  Google Scholar 

  68. Lundy DW. Subtrochanteric femoral fractures. J Am Acad Orthop Surg. 2007;15(11):663–71.

    Article  PubMed  Google Scholar 

  69. Kinast C, Bolhofner BR, Mast JW, Ganz R. Subtrochanteric fractures of the femur: Results of treatment with the 95 degrees condylar blade-plate. Clin Orthop Relat Res. 1989;238:122–30.

    Google Scholar 

  70. Wiss DA, Brien WW. Subtrochanteric fractures of the femur: results of treatment by interlocking nailing. Clin Orthop Relat Res. 1992;283:231–6.

    Google Scholar 

  71. Kang S, McAndrew MP, Johnson KD. The reconstruction locked nail for complex fractures of the proximal femur. J Orthop Trauma. 1995;9(6):453–63.

    Article  CAS  PubMed  Google Scholar 

  72. Pai CH. Dynamic condylar screw for subtrochanteric femur fractures with greater trochanteric extension. J Orthop Trauma. 1996;10(5):317–22.

    Article  CAS  PubMed  Google Scholar 

  73. French BG, Tornetta P 3rd. Use of an interlocked cephalomedullary nail for subtrochanteric fracture stabilization. Clin Orthop Relat Res. 1998;348:95–100.

    Article  Google Scholar 

  74. Haidukewych GJ, Berry DJ. Nonunion of fractures of the subtrochanteric region of the femur. Clin Orthop Relat Res. 2004;419:185–8.

    Article  Google Scholar 

  75. Wu C. Locked nailing for shortened subtrochanteric nonunions: a one-stage treatment. Clin Orthop Relat Res. 2009;467(1):254–9.

    Article  PubMed  Google Scholar 

  76. Barquet A, Mayora G, Fregeiro J, López L, Rienzi D, Francescoli L. The treatment of subtrochanteric nonunions with the long gamma nail twenty-six patients with a minimum 2-year follow-up. J Orthop Trauma. 2004;18(6):346–53.

    Article  PubMed  Google Scholar 

  77. Duffy GP, Wood MB, Rock MG, Sim FH. Vascularized free fibular transfer combined with autografting for the management of fracture nonunions associated with radiation therapy. J Bone Joint Surg Am. 2000;82(4):544–54.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Roman A. Hayda MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Science+Business Media LLC

About this chapter

Cite this chapter

Hayda, R.A. (2018). Proximal Femur Nonunions. In: Agarwal, A. (eds) Nonunions. Springer, Boston, MA. https://doi.org/10.1007/978-1-4939-7178-7_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-7178-7_9

  • Published:

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4939-7176-3

  • Online ISBN: 978-1-4939-7178-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics