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Application of Poly(meth)acrylate Copolymers for Oral Multiparticulate Drug Delivery Systems

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Multiparticulate Drug Delivery

Part of the book series: Advances in Delivery Science and Technology ((ADST))

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Abstract

Poly(meth)acrylates were introduced to the pharmaceutical market in 1954 for the use in oral dosage forms in order to replace time-consuming sugar coatings on tablets in the beginning, closely followed by more functional versions in order to create taste masked and protective coatings or enteric-coated as well as extended release-coated particles, but also for the creation of extended release matrix structures.

Newer developments cover the field of multilayered coatings for longer drug release, specific release profiles or a more precise targeting for regional drug release. Especially the latter can be influenced successfully by the addition of specific ions inside such coated dosage forms in order to create modified/pulsed drug release profiles for improved therapies.

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Authors and Affiliations

  1. Evonik Nutrition & Care GmbH, Kirschenallee, D-64293, Darmstadt, Germany

    Theresia Kuntz, Wolfgang Weisbrod & Brigitte Skalsky

  2. Evonik India Pvt. Ltd., Saki Vihar Road, Saki Naka, Andheri (E), Mumbai, India

    Subhashis Chakraborty

Authors
  1. Theresia Kuntz
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  2. Wolfgang Weisbrod
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  3. Subhashis Chakraborty
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  4. Brigitte Skalsky
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Correspondence to Theresia Kuntz .

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Editors and Affiliations

  1. VP & Chief Scientific Officer, Colorcon Inc., Harleysville, Pennsylvania, USA

    Ali R. Rajabi-Siahboomi

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Kuntz, T., Weisbrod, W., Chakraborty, S., Skalsky, B. (2017). Application of Poly(meth)acrylate Copolymers for Oral Multiparticulate Drug Delivery Systems. In: Rajabi-Siahboomi, A. (eds) Multiparticulate Drug Delivery. Advances in Delivery Science and Technology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-7012-4_10

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