Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) have analgesic, anti-inflammatory, and antipyretic properties. They work by inhibiting the prostaglandins synthesis through cyclooxygenase pathway. They play a role in treatment of different acute or chronic nociceptive pain conditions such as osteoarthritis, low back pain, rheumatoid arthritis, and inflammatory arthropathies. NSAIDs can have adverse effects on different systems including the gastrointestinal, renal, and cardiovascular systems. Side effects of NSAIDs can limit their use despite their analgesic benefits. There is an emerging role for the NSAIDs for treatment of acute pain in the perioperative period.
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Suggested Reading
Benzon H, Raja SN, Fishman SM, Liu S, Cohen SP. Essentials of pain medicine. 3rd ed.
Fishman SM, Ballantyne JC, Rathmell JP. Bonica’s management of pain. 4th ed.
Katzung B, Masters S, Trevor A. Basic and clinical pharmacology. 12th ed. Lange Basic Science. McGraw Hill Companies; 2012. ISBN-13: 978-0071764018; ISBN-10: 0071764011
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Tolba, R. (2017). Nonsteroidal Anti-inflammatory Drugs (NSAIDs). In: Pope, J., Deer, T. (eds) Treatment of Chronic Pain Conditions. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-6976-0_21
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DOI: https://doi.org/10.1007/978-1-4939-6976-0_21
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