Abstract
Personalized medicine simply means the prescription of specific therapeutics best suited for an individual. It is usually based on pharmacogenetic, pharmacogenomic, transcriptomic, pharmacoproteomic and pharmacometabolomic information. Other individual variations in patients and environmental factors are also taken into consideration (Jain 2015). Personalized medicine means improving healthcare by incorporating early detection of disease, preventive medicine, rational drug discovery and development, and monitoring of therapy. Concept of personalized medicine as systems medicine is the best way of integrating new technologies and translating them into clinical application for improving healthcare. Application of nanobiotechnology is described for personalized management of cancer and cardiovascular disorders. Advances in nanobiotechnology will facilitate the development of personalized medicine by:
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Nanodiagnostics will improve the sensitivity and extend the present limits of molecular diagnostics/molecular imaging of CNS disorders.
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Nanotechnology can be integrated in detection of biomarkers, POC devices, biochips and biosensors.
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Biomarkers discovered by use of nanodiagnostics will facilitate the development of new personalized drugs for various disorders.
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Nanobiotechnology will facilitate integration of diagnosis and therapy, which is an important part personalized medicine.
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Jain, K.K. (2017). Nanobiotechnology and Personalized Medicine. In: The Handbook of Nanomedicine. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6966-1_16
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DOI: https://doi.org/10.1007/978-1-4939-6966-1_16
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