Abstract
Mucinous breast lesions represent a heterogeneous group of entities that are described together based on the presence of mucin as a common feature. They range from benign conditions like cysts and dilated ducts with luminal mucin to mucocele-like lesions that can be associated with a range of epithelial proliferations and to mucin-producing malignant neoplasms of mucinous carcinoma and solid papillary carcinoma with mucin production.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Shim JY, Sahin AA. Mucinous lesions of the breast. Surgical Pathology2, 2009;413–40.
O’Connell JT, Shao ZM, Drori E, Basbaum CB, Barsky SH. Altered mucin expression is a field change that accompanies mucinouc (colloid) breast carcinoma histogenesis. Hum Pathol 1998;29:1517–23.
Sapino A, Sneige N, Eusebi V. Mucoepidermoid carcinoma. In: Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, van de Vijver MJ, editors. WHO classification of tumours of the breast. Lyon: IARC; 2012. p. 58.
Honma N, Sakamoto G, Ikenaga M, Kuroiwa K, Younes M, Takubo K. Mucinous cystadenocarcinoma of the breast. A case report and review of the literature. Arch Pathol Lab Med. 2003;127:1031–3.
Tan PH, Tse GM, Bay BH. Mucinous breast lesions: diagnostic challenges. J Clin Pathol. 2008;61:11–9.
Gadre SA, Perkins GH, Sahin AA, Sneige N, Deavers MT, Middleton LP. Neovascularization in mucinous ductal carcinoma in situ suggests an alternative pathway for invasion. Histopathology. 2008;53:545–53.
Jaffer S, Bleiweiss IJ, Nagi CS. Benign mucocele-like lesions of the breast: revisited. Mod Pathol. 2011;24:683–7.
Rakha EA, Shaaban AM, Haider SA, Jenkins J, Menon S, Johnson C, Yamaguchi R, Murphy A, Liston J, Cornford E, Hamilton L, James J, Ellis IO, Lee AH. Outcome of pure mucocele-like lesions diagnosed on breast core biopsy. Histopathology. 2013;62:894–8.
Sutton B, Davion S, Feldman M, Siziopikou K, Mendelson E, Sullivan M. Mucocele-like lesions diagnosed on breast core biopsy: assessment of upgrade rate and need for surgical excision. Am J Clin Pathol. 2012;138:783–8.
Begum SM, Jara-Lazaro AR, Thike AA, Tse GM, Wong JS, Ho JT, Tan PH. Mucin extravasation in breast core biopsies—clinical significance and outcome correlation. Histopathology. 2009;55:609-17.
Barbashina V, Corben AD, Akram M, Vallejo C, Tan LK. Mucinous micropapillary carcinoma of the breast: an aggressive counterpart to conventional pure mucinous tumors. Hum Pathol. 2013;44:1577–85.
Bussolati G, Sapino A. Mucinous carcinomas and carcinoma with signet-ring-cell differentiation. In: Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, van de Vijver MJ, editors. WHO classification of tumours of the breast. Lyon: IARC; 2012. p. 60.
Tan PH, Schnitt SJ, van de Vijver MJ, Ellis IO, Lakhani SR. Papillary and neuroendocrine breast lesions: the WHO stance. Histopathology. 2015;66:761–70.
Tan BY, Thike AA, Ellis IO, Tan PH. Clinicopathologic characteristics of solid papillary carcinoma of the breast. Am J Surg Pathol. 2016;40:1334–42.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Science+Business Media LLC
About this chapter
Cite this chapter
Tan, P.H., Sahin, A.A. (2017). Mucinous Lesions. In: Atlas of Differential Diagnosis in Breast Pathology. Atlas of Anatomic Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-6697-4_6
Download citation
DOI: https://doi.org/10.1007/978-1-4939-6697-4_6
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4939-6695-0
Online ISBN: 978-1-4939-6697-4
eBook Packages: MedicineMedicine (R0)