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Understanding the Pathophysiology of Penile Cancer and Its Preneoplastic Lesions

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Part of the Current Clinical Urology book series (CCU)

Abstract

Squamous cell carcinoma of the penis is a rare malignancy that can develop anywhere on the penis. The epidemiology, risk factors, and pathophysiology of penile carcinoma are described here. Human papillomavirus has been proven to play a pivotal role in a significant subset of cases and is discussed in detail. Penile intraepithelial neoplasia refers to the penile preneoplastic lesions. These lesions demonstrate variable risk to progression to invasive cancer and are reviewed in completeness.

Keywords

  • Penile cancer
  • Squamous cell carcinoma
  • Human papillomavirus
  • Penile intraepithelial neoplasia

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Correspondence to Anna R. Giuliano Ph.D. .

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Baumgarten, A.S., McCormick, B.Z., Ashouri, K.B., Dhillon, J., Giuliano, A.R., Spiess, P.E. (2017). Understanding the Pathophysiology of Penile Cancer and Its Preneoplastic Lesions. In: Spiess, P. (eds) Penile Cancer. Current Clinical Urology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6679-0_1

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  • DOI: https://doi.org/10.1007/978-1-4939-6679-0_1

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