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Sleep Disorders Medicine pp 41–53Cite as

Effects of Sleep Deprivation and Sleepiness on Society and Driving

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Abstract

Sleep deprivation represents a major public health issue, and increasing the proportion of the population that achieves adequate sleep has been identified as a national health priority. Despite this, insufficient habitual sleep duration is still highly prevalent, with approximately a third of US adults achieving less than 6 h of sleep on average. Habitual short sleep duration cuts across all segments of the population and is associated with weight gain and obesity, heart disease, diabetes, poor cognitive performance, stress, and other adverse outcomes, including mortality. This chapter begins by conceptualizing the effects of sleep in the context of society. This is done largely through a social–ecological framework. Then, this chapter aims to summarize the health effects of sleep deprivation across dimensions of cardiometabolic disease risk, neurocognitive function, and psychological well-being. Then, the chapter will further explore these effects across age, race/ethnicity, gender/sex, relationship status, and occupation. A section will devote specific attention to the role of sleep deprivation in driving accidents. Finally, the chapter ends with a summary and conclusions, with recommendations for future directions.

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References

  1. Colten HR, Altevogt BM, Institute of Medicine Committee on Sleep Medicine and Research (2006) Sleep disorders and sleep deprivation: an unmet public health problem. Institute of Medicine, National Academies Press, Washington, DC

    Google Scholar 

  2. Ulmer C, Wolman DM, Johns MME, Institute of Medicine Committee on Optimizing Graduate Medical Trainee (Resident) Hours and Work Schedules to Improve Patient Safety (2009) Resident duty hours: enhancing sleep, supervision, and safety. National Academies Press, Washington, DC

    Google Scholar 

  3. Office of Disease Prevention and Health Promotion (2011) Healthy people 2020 objective topic areas. US Department of Health and Human Services, Washington, DC

    Google Scholar 

  4. Zee PC, Badr MS, Kushida C et al (2014) Strategic opportunities in sleep and circadian research: report of the joint task force of the sleep research society and american academy of sleep medicine. Sleep 37(2):219–227

    Article  PubMed Central  PubMed  Google Scholar 

  5. Grandner MA, Patel NP, Hale L, Moore M (2010) Mortality associated with sleep duration: the evidence, the possible mechanisms, and the future. Sleep Med Rev 14:191–203

    Article  PubMed  Google Scholar 

  6. Bronfenbrenner U (1977) Toward an experimental ecology of human development. Am Psychol 32:513–531

    Article  Google Scholar 

  7. Minkel JD, Banks S, Htaik O et al (2012) Sleep deprivation and stressors: evidence for elevated negative affect in response to mild stressors when sleep deprived. Emotion 12(5):1015–1020

    Article  PubMed Central  PubMed  Google Scholar 

  8. Minkel J, Htaik O, Banks S, Dinges D (2011) Emotional expressiveness in sleep-deprived healthy adults. Behav Sleep Med 9(1):5–14

    Article  PubMed Central  PubMed  Google Scholar 

  9. van der Helm E, Gujar N, Walker MP (2010) Sleep deprivation impairs the accurate recognition of human emotions. Sleep 33(3):335–342

    Article  PubMed Central  PubMed  Google Scholar 

  10. Grandner MA, Patel NP, Gehrman PR, Perlis ML, Pack AI (2010) Problems associated with short sleep: bridging the gap between laboratory and epidemiological studies. Sleep Med Rev 14:239–247

    Article  PubMed  Google Scholar 

  11. Knutson KL (2010) Sleep duration and cardiometabolic risk: a review of the epidemiologic evidence. Best Pract Res Clin Endocrinol Metab. 24(5):731–743

    Article  PubMed Central  PubMed  Google Scholar 

  12. Altman NG, Izci-Balserak B, Schopfer E et al (2012) Sleep duration versus sleep insufficiency as predictors of cardiometabolic health outcomes. Sleep Med 13(10):1261–1270

    Article  PubMed Central  PubMed  Google Scholar 

  13. Patel SR, Blackwell T, Redline S et al (2008) The association between sleep duration and obesity in older adults. Int J Obes (Lond). 32(12):1825–1834

    Article  CAS  PubMed Central  Google Scholar 

  14. Patel SR, Hu FB (2008) Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring). 16(3):643–653

    Article  PubMed Central  PubMed  Google Scholar 

  15. Grandner MA, Buxton OM, Jackson N, Sands-Lincoln M, Pandey A, Jean-Louis G (2013) Extreme sleep durations and increased C-reactive protein: effects of sex and ethnoracial group. Sleep 36(5):769–779

    PubMed Central  PubMed  Google Scholar 

  16. Meng L, Zheng Y, Hui R (2013) The relationship of sleep duration and insomnia to risk of hypertension incidence: a meta-analysis of prospective cohort studies. Hypertens Res 36(11):985–995. PubMed PMID: 24005775; PubMed Central PMCID: PMC3819519

    Google Scholar 

  17. Cappuccio FP, Cooper D, D’Elia L, Strazzullo P, Miller MA (2011) Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J 32(12):1484–1492

    Article  PubMed  Google Scholar 

  18. Cappuccio FP, Miller MA (2011) Are short bad sleep nights a hindrance to a healthy heart? Sleep 34(11):1457–1458

    Article  PubMed Central  PubMed  Google Scholar 

  19. Sands MR, Lauderdale DS, Liu K et al (2012) Short sleep duration is associated with carotid intima-media thickness among men in the coronary artery risk development in young adults (CARDIA) study. Stroke 43(11):2858–2864

    Article  PubMed Central  PubMed  Google Scholar 

  20. Buxton OM, Marcelli E (2010) Short and long sleep are positively associated with obesity, diabetes, hypertension, and cardiovascular disease among adults in the United States. Soc Sci Med 71(5):1027–1036

    Article  PubMed  Google Scholar 

  21. Vgontzas AN, Fernandez-Mendoza J, Liao D, Bixler EO (2013) Insomnia with objective short sleep duration: the most biologically severe phenotype of the disorder. Sleep Med Rev 17(4):241–254

    Article  PubMed Central  PubMed  Google Scholar 

  22. Morselli LL, Guyon A, Spiegel K (2012) Sleep and metabolic function. Pflugers Arch 463(1):139–160

    Article  CAS  PubMed  Google Scholar 

  23. Lucassen EA, Rother KI, Cizza G (2012) Interacting epidemics? Sleep curtailment, insulin resistance, and obesity. Ann N Y Acad Sci 1264(1):110–134

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  24. Barone MT, Menna-Barreto L (2011) Diabetes and sleep: a complex cause-and-effect relationship. Diabetes Res Clin Pract 91(2):129–137

    Article  PubMed  Google Scholar 

  25. Zizi F, Jean-Louis G, Brown CD, Ogedegbe G, Boutin-Foster C, McFarlane SI (2010) Sleep duration and the risk of diabetes mellitus: epidemiologic evidence and pathophysiologic insights. Curr Diab Rep. 10(1):43–47

    Article  PubMed Central  PubMed  Google Scholar 

  26. Chaput JP, Leblanc C, Perusse L, Despres JP, Bouchard C, Tremblay A (2009) Risk factors for adult overweight and obesity in the Quebec Family Study: have we been barking up the wrong tree? Obesity (Silver Spring). 17(10):1964–1970

    Article  PubMed  Google Scholar 

  27. Tuomilehto H, Peltonen M, Partinen M et al (2009) Sleep duration, lifestyle intervention, and incidence of type 2 diabetes in impaired glucose tolerance: the finnish diabetes prevention study. Diabetes Care 32(11):1965–1971

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  28. Grandner MA, Kripke DF, Naidoo N, Langer RD (2010) Relationships among dietary nutrients and subjective sleep, objective sleep, and napping in women. Sleep Med 11(2):180–184

    Article  PubMed  Google Scholar 

  29. Reynolds CF 3rd, Serody L, Okun ML et al (2010) Protecting sleep, promoting health in later life: a randomized clinical trial. Psychosom Med 72(2):178–186

    Article  CAS  PubMed  Google Scholar 

  30. Knutson KL, Spiegel K, Penev P, Van Cauter E (2007) The metabolic consequences of sleep deprivation. Sleep Med Rev 11(3):163–178

    Article  PubMed Central  PubMed  Google Scholar 

  31. Shechter A, Grandner MA, St-Onge MP (2014) The role of sleep in the control of food intake. Am J Lifestyle Med 8(6):371–374. PubMed PMID: 27065757; PubMed Central PMCID: PMC4824633

    Google Scholar 

  32. St-Onge MP, Roberts AL, Chen J et al (2011) Short sleep duration increases energy intakes but does not change energy expenditure in normal-weight individuals. Am J Clin Nutr 94(2):410–416

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  33. Spaeth AM, Dinges DF, Goel N (2014) Sex and race differences in caloric intake during sleep restriction in healthy adults. Am J Clin Nutr 100(2):559–566

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  34. Spaeth AM, Dinges DF, Goel N (2013) Effects of experimental sleep restriction on weight gain, caloric intake, and meal timing in healthy adults. Sleep 36(7):981–990

    Article  PubMed Central  PubMed  Google Scholar 

  35. Markwald RR, Melanson EL, Smith MR et al (2013) Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci U S A. 110(14):5695–5700

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  36. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372(6505):425–432

    Article  CAS  PubMed  Google Scholar 

  37. Considine RV, Sinha MK, Heiman ML et al (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334(5):292–295

    Article  CAS  PubMed  Google Scholar 

  38. Caro JF, Sinha MK, Kolaczynski JW, Zhang PL, Considine RV (1996) Leptin: the tale of an obesity gene. Diabetes 45(11):1455–1462

    Article  CAS  PubMed  Google Scholar 

  39. Boeke CE, Storfer-Isser A, Redline S, Taveras EM (2014) Childhood sleep duration and quality in relation to leptin concentration in two cohort studies. Sleep 37(3):613–620

    Article  PubMed Central  PubMed  Google Scholar 

  40. Hart CN, Carskadon MA, Considine RV et al (2013) Changes in children’s sleep duration on food intake, weight, and leptin. Pediatrics 132(6):e1473–e1480

    Article  PubMed  Google Scholar 

  41. Taheri S, Lin L, Austin D, Young T, Mignot E (2004) Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 1(3):e62

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  42. Stern JH, Grant AS, Thomson CA, et al (2013) Short sleep duration is associated with decreased serum leptin, increased energy intake, and decreased diet quality in postmenopausal women. Obesity (Silver Spring)

    Google Scholar 

  43. Charles LE, Gu JK, Andrew ME, Violanti JM, Fekedulegn D, Burchfiel CM (2011) Sleep duration and biomarkers of metabolic function among police officers. J Occup Environ Med 53(8):831–837

    Article  PubMed  Google Scholar 

  44. Moraes W, Poyares D, Zalcman I et al (2013) Association between body mass index and sleep duration assessed by objective methods in a representative sample of the adult population. Sleep Med 14(4):312–318

    Article  CAS  PubMed  Google Scholar 

  45. Hayes AL, Xu F, Babineau D, Patel SR (2011) Sleep duration and circulating adipokine levels. Sleep 34(2):147–152

    Article  PubMed Central  PubMed  Google Scholar 

  46. Koo M, Lai NS, Chiang JK (2013) Short duration of sleep is associated with hyperleptinemia in Taiwanese adults. J Clin Sleep Med 9(10):1049–1055

    PubMed Central  PubMed  Google Scholar 

  47. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402(6762):656–660

    Article  CAS  PubMed  Google Scholar 

  48. Nakazato M, Murakami N, Date Y et al (2001) A role for ghrelin in the central regulation of feeding. Nature 409(6817):194–198

    Article  CAS  PubMed  Google Scholar 

  49. Ueno H, Shiiya T, Nakazato M (2010) Translational research of ghrelin. Ann N Y Acad Sci 1200:120–127

    Article  CAS  PubMed  Google Scholar 

  50. Heppner KM, Tong J (2014) Regulation of glucose metabolism by the ghrelin system: multiple players and multiple actions. Eur J Endocrinol

    Google Scholar 

  51. Tschop M, Smiley DL, Heiman ML (2000) Ghrelin induces adiposity in rodents. Nature 407(6806):908–913

    Article  CAS  PubMed  Google Scholar 

  52. Littman AJ, Vitiello MV, Foster-Schubert K et al (2007) Sleep, ghrelin, leptin and changes in body weight during a 1-year moderate-intensity physical activity intervention. Int J Obes (Lond). 31(3):466–475

    Article  CAS  Google Scholar 

  53. Al-Disi D, Al-Daghri N, Khanam L et al (2010) Subjective sleep duration and quality influence diet composition and circulating adipocytokines and ghrelin levels in teen-age girls. Endocr J 57(10):915–923

    Article  CAS  PubMed  Google Scholar 

  54. Spiegel K, Knutson K, Leproult R, Tasali E, Van Cauter E (2005) Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. J Appl Physiol 99(5):2008–2019

    Article  CAS  PubMed  Google Scholar 

  55. Spiegel K, Leproult R, L’Hermite-Baleriaux M, Copinschi G, Penev PD, Van Cauter E (2004) Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. J Clin Endocrinol Metab 89(11):5762–5771

    Article  CAS  PubMed  Google Scholar 

  56. Spiegel K, Leproult R, Van Cauter E (1999) Impact of sleep debt on metabolic and endocrine function. Lancet 354(9188):1435–1439

    Article  CAS  PubMed  Google Scholar 

  57. Tasali E, Leproult R, Spiegel K (2009) Reduced sleep duration or quality: relationships with insulin resistance and type 2 diabetes. Prog Cardiovasc Dis. Mar-Apr 51(5):381–391

    Article  CAS  Google Scholar 

  58. Broussard JL, Ehrmann DA, Van Cauter E, Tasali E, Brady MJ (2012) Impaired insulin signaling in human adipocytes after experimental sleep restriction: a randomized, crossover study. Ann Intern Med 157(8):549–557

    Article  PubMed Central  PubMed  Google Scholar 

  59. Van Cauter E (2011) Sleep disturbances and insulin resistance. Diabet Med 28(12):1455–1462

    Article  CAS  PubMed  Google Scholar 

  60. Buxton OM, Pavlova M, Reid EW, Wang W, Simonson DC, Adler GK (2010) Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes 59(9):2126–2133

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  61. Grandner MA, Chakravorty S, Perlis ML, Oliver L, Gurubhagavatula I (2014) Habitual sleep duration associated with self-reported and objectively determined cardiometabolic risk factors. Sleep Med 15(1):42–50

    Article  PubMed  Google Scholar 

  62. Libby P (2006) Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr 83(2):456S–460S

    CAS  PubMed  Google Scholar 

  63. Vgontzas AN, Zoumakis E, Bixler EO et al (2004) Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab 89(5):2119–2126

    Article  CAS  PubMed  Google Scholar 

  64. Irwin MR, Wang M, Campomayor CO, Collado-Hidalgo A, Cole S (2006) Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation. Arch Intern Med 166(16):1756–1762

    Article  CAS  PubMed  Google Scholar 

  65. Haack M, Sanchez E, Mullington JM (2007) Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep 30(9):1145–1152

    Article  PubMed Central  PubMed  Google Scholar 

  66. van Leeuwen WM, Lehto M, Karisola P et al (2009) Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP. PLoS ONE 4(2):e4589

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  67. Meier-Ewert HK, Ridker PM, Rifai N et al (2004) Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol 43(4):678–683

    Article  CAS  PubMed  Google Scholar 

  68. Patel SR, Zhu X, Storfer-Isser A et al (2009) Sleep duration and biomarkers of inflammation. Sleep 32(2):200–204

    Article  PubMed Central  PubMed  Google Scholar 

  69. von Kanel R, Ancoli-Israel S, Dimsdale JE et al (2010) Sleep and biomarkers of atherosclerosis in elderly Alzheimer caregivers and controls. Gerontology. 56(1):41–50

    Article  CAS  Google Scholar 

  70. Taveras EM, Rifas-Shiman SL, Rich-Edwards JW, Mantzoros CS (2011) Maternal short sleep duration is associated with increased levels of inflammatory markers at 3 years postpartum. Metabolism. 60(7):982–986

    Article  CAS  PubMed  Google Scholar 

  71. Matthews KA, Zheng H, Kravitz HM et al (2010) Are inflammatory and coagulation biomarkers related to sleep characteristics in mid-life women?: study of Women’s health across the nation sleep study. Sleep 33(12):1649–1655

    Article  PubMed Central  PubMed  Google Scholar 

  72. Albert MA (2011) Biomarkers and heart disease. J Clin Sleep Med 7(5 Suppl):S9–S11

    PubMed Central  PubMed  Google Scholar 

  73. Nilsson PM, Viljoen A, Wierzbicki AS (2010) Cardiovascular risk factors. In: Holt RIG, Cockram C, Flyvbjerg A, Goldstein BJ (eds) Textbook of diabetes, 4th edn. Wiley-Blackwell, Chichester, pp 657–683

    Google Scholar 

  74. Ivy JR, Bailey MA (2014) Pressure natriuresis and the renal control of arterial blood pressure. J Physiol 592(Pt 18):3955–3967

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  75. Hart EC, Charkoudian N (2014) Sympathetic neural regulation of blood pressure: influences of sex and aging. Physiology 29(1):8–15

    Article  CAS  PubMed  Google Scholar 

  76. Meng L, Zheng Y, Hui R (2013) The relationship of sleep duration and insomnia to risk of hypertension incidence: a meta-analysis of prospective cohort studies. Hypertens Res 36(11):985–995

    Article  PubMed Central  PubMed  Google Scholar 

  77. Bjorvatn B, Sagen IM, Oyane N et al (2007) The association between sleep duration, body mass index and metabolic measures in the Hordaland Health Study. J Sleep Res 16(1):66–76

    Article  PubMed  Google Scholar 

  78. Ayala DE, Moya A, Crespo JJ et al (2013) Circadian pattern of ambulatory blood pressure in hypertensive patients with and without type 2 diabetes. Chronobiol Int 30(1–2):99–115

    Article  PubMed  Google Scholar 

  79. Hori H, Teraishi T, Sasayama D et al (2011) Poor sleep is associated with exaggerated cortisol response to the combined dexamethasone/CRH test in a non-clinical population. J Psychiatr Res 45(9):1257–1263

    Article  PubMed  Google Scholar 

  80. Lattova Z, Keckeis M, Maurovich-Horvat E et al (2011) The stress hormone system in various sleep disorders. J Psychiatr Res 45(9):1223–1228

    PubMed  Google Scholar 

  81. Bose M, Olivan B, Laferrere B (2009) Stress and obesity: the role of the hypothalamic-pituitary-adrenal axis in metabolic disease. Curr Opin Endocrinol Diabetes Obes 16(5):340–346

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  82. Vgontzas AN, Bixler EO, Chrousos GP (2006) Obesity-related sleepiness and fatigue: the role of the stress system and cytokines. Ann N Y Acad Sci 1083:329–344

    Article  CAS  PubMed  Google Scholar 

  83. Vgontzas AN, Mastorakos G, Bixler EO, Kales A, Gold PW, Chrousos GP (1999) Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications. Clin Endocrinol (Oxf). 51(2):205–215

    Article  CAS  PubMed  Google Scholar 

  84. Vgontzas AN, Tsigos C, Bixler EO, et al (1998) Chronic insomnia and activity of the stress system: a preliminary study. J Psychosom Res 45(1 Spec no):21–31

    Google Scholar 

  85. Robertson MD, Russell-Jones D, Umpleby AM, Dijk DJ (2013) Effects of three weeks of mild sleep restriction implemented in the home environment on multiple metabolic and endocrine markers in healthy young men. Metabolism. 62(2):204–211

    Article  CAS  PubMed  Google Scholar 

  86. Gangwisch JE, Malaspina D, Babiss LA et al (2010) Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent Health. Sleep 33(7):956–961

    Article  PubMed Central  PubMed  Google Scholar 

  87. Gangwisch JE, Heymsfield SB, Boden-Albala B, et al (2008) Sleep duration as a risk factor for diabetes incidence in a large U.S. sample. Sleep 30(12):1667–1673. Epub 2008/02/06. PubMed PMID: 18246976; PubMed Central PMCID: PMC2276127

    Google Scholar 

  88. Specker BL, Binkley T, Vukovich M, Beare T (2007) Volumetric bone mineral density and bone size in sleep-deprived individuals. Osteoporos Int J Established Result Cooperation Eur Found Osteopor Natl Osteopor Found USA 18(1):93–99

    Article  CAS  Google Scholar 

  89. Fallone G, Acebo C, Seifer R, Carskadon MA (2005) Experimental restriction of sleep opportunity in children: effects on teacher ratings. Sleep 28(12):1561–1567

    Article  PubMed  Google Scholar 

  90. Touchette E, Petit D, Seguin JR, Boivin M, Tremblay RE, Montplaisir JY (2007) Associations between sleep duration patterns and behavioral/cognitive functioning at school entry. Sleep 30(9):1213–1219

    Article  PubMed Central  PubMed  Google Scholar 

  91. Friedman NP, Corley RP, Hewitt JK, Wright KP Jr (2009) Individual differences in childhood sleep problems predict later cognitive executive control. Sleep 32(3):323–333

    Article  PubMed Central  PubMed  Google Scholar 

  92. Corkum P, Tannock R, Moldofsky H (1998) Sleep disturbances in children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 37(6):637–646

    Article  CAS  PubMed  Google Scholar 

  93. Liu X, Hubbard JA, Fabes RA, Adam JB (2006) Sleep disturbances and correlates of children with autism spectrum disorders. Child psychiatry and human development. Winter 37(2):179–191

    Article  Google Scholar 

  94. Patzold LM, Richdale AL, Tonge BJ (1998) An investigation into sleep characteristics of children with autism and Asperger’s Disorder. J Paediatr Child Health 34(6):528–533

    Article  CAS  PubMed  Google Scholar 

  95. Polimeni MA, Richdale AL, Francis AJ (2005) A survey of sleep problems in autism, Asperger’s disorder and typically developing children. J Intellect Disabil Res JIDR 49(Pt 4):260–268

    Article  CAS  PubMed  Google Scholar 

  96. Wiggs L, Stores G (2004) Sleep patterns and sleep disorders in children with autistic spectrum disorders: insights using parent report and actigraphy. Dev Med Child Neurol 46(6):372–380

    Article  PubMed  Google Scholar 

  97. Goodlin-Jones BL, Tang K, Liu J, Anders TF (2008) Sleep patterns in preschool-age children with autism, developmental delay, and typical development. J Am Acad Child Adolesc Psychiatry 47(8):930–938

    Article  PubMed  Google Scholar 

  98. Krakowiak P, Goodlin-Jones B, Hertz-Picciotto I, Croen LA, Hansen RL (2008) Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study. J Sleep Res 17(2):197–206

    Article  PubMed Central  PubMed  Google Scholar 

  99. Richdale AL, Prior MR (1995) The sleep/wake rhythm in children with autism. Eur Child Adolesc Psychiatry 4(3):175–186

    Article  CAS  PubMed  Google Scholar 

  100. Goldman SE, Richdale AL, Clemons T, Malow BA (2012) Parental sleep concerns in autism spectrum disorders: variations from childhood to adolescence. J Autism Dev Disord 42(4):531–538

    Article  PubMed  Google Scholar 

  101. Weiss R, Bremer AA, Lustig RH (2013) What is metabolic syndrome, and why are children getting it? Ann N Y Acad Sci 1281:123–140

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  102. Sokolovic N, Kuriyan R, Kurpad AV, Thomas T (2013) Sleep and birthweight predict visceral adiposity in overweight/obese children. Pediatric obesity 8(3):e41–e44

    Article  CAS  PubMed  Google Scholar 

  103. Webb WB, Agnew HW Jr (1974) The effects of a chronic limitation of sleep length. Psychophysiology 11(3):265–274

    Article  CAS  PubMed  Google Scholar 

  104. Webb WB, Agnew HW Jr (1975) The effects on subsequent sleep of an acute restriction of sleep length. Psychophysiology 12(4):367–370

    Article  CAS  PubMed  Google Scholar 

  105. McKnight-Eily LR, Eaton DK, Lowry R, Croft JB, Presley-Cantrell L, Perry GS (2011) Relationships between hours of sleep and health-risk behaviors in US adolescent students. Prev Med 53(4–5):271–273

    Article  PubMed  Google Scholar 

  106. Jenni OG, Carskadon MA (2007) Sleep behavior and sleep regulation from infancy through adolescence: normative aspects. Sleep medicine clinics. 9;2(3):321–329

    Google Scholar 

  107. Wolfson AR, Carskadon MA (1998) Sleep schedules and daytime functioning in adolescents. Child Dev 69(4):875–887

    Article  CAS  PubMed  Google Scholar 

  108. Williams JA, Zimmerman FJ, Bell JF (2013) Norms and trends of sleep time among US children and adolescents. JAMA pediatrics. 167(1):55–60

    Article  PubMed  Google Scholar 

  109. Jenni OG (2013) How much sleep is “normal” in children and adolescents? JAMA pediatrics 167(1):91–92

    Article  PubMed  Google Scholar 

  110. Peigneux P, Laureys S, Delbeuck X, Maquet P (2001) Sleeping brain, learning brain. The role of sleep for memory systems. NeuroReport 12(18):A111–A124

    Article  CAS  PubMed  Google Scholar 

  111. Laureys S, Peigneux P, Phillips C et al (2001) Experience-dependent changes in cerebral functional connectivity during human rapid eye movement sleep. Neuroscience 105(3):521–525

    Article  CAS  PubMed  Google Scholar 

  112. Curcio G, Ferrara M, De Gennaro L (2006) Sleep loss, learning capacity and academic performance. Sleep Med Rev 10(5):323–337

    Article  PubMed  Google Scholar 

  113. Alhola P, Polo-Kantola P (2007) Sleep deprivation: Impact on cognitive performance. Neuropsychiatric disease and treatment. 3(5):553–567

    PubMed Central  PubMed  Google Scholar 

  114. Talbot LS, McGlinchey EL, Kaplan KA, Dahl RE, Harvey AG (2010) Sleep deprivation in adolescents and adults: changes in affect. Emotion 10(6):831–841

    Article  PubMed Central  PubMed  Google Scholar 

  115. Lee YJ, Cho SJ, Cho IH, Kim SJ (2012) Insufficient sleep and suicidality in adolescents. Sleep 35(4):455–460

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  116. Ruiter ME, Decoster J, Jacobs L, Lichstein KL (2011) Normal sleep in African-Americans and Caucasian-Americans: a meta-analysis. Sleep Med 12(3):209–214

    Article  PubMed  Google Scholar 

  117. Hong S, Mills PJ, Loredo JS, Adler KA, Dimsdale JE (2005) The association between interleukin-6, sleep, and demographic characteristics. Brain Behav Immun 19(2):165–172

    Article  CAS  PubMed  Google Scholar 

  118. Mokhlesi B, Pannain S, Ghods F, Knutson KL (2012) Predictors of slow-wave sleep in a clinic-based sample. J Sleep Res 21(2):170–175

    Article  PubMed  Google Scholar 

  119. Mezick EJ, Matthews KA, Hall M et al (2008) Influence of race and socioeconomic status on sleep: Pittsburgh SleepSCORE project. Psychosom Med 70(4):410–416

    Article  PubMed Central  PubMed  Google Scholar 

  120. Redline S, Kirchner HL, Quan SF, Gottlieb DJ, Kapur V, Newman A (2004) The effects of age, sex, ethnicity, and sleep-disordered breathing on sleep architecture. Arch Intern Med 164(4):406–418

    Article  PubMed  Google Scholar 

  121. Hall MH, Matthews KA, Kravitz HM et al (2009) Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep study. Sleep 32(1):73–82

    PubMed Central  PubMed  Google Scholar 

  122. Jean-Louis G, Kripke DF, Ancoli-Israel S, Klauber MR, Sepulveda RS (2000) Sleep duration, illumination, and activity patterns in a population sample: effects of gender and ethnicity. Biol Psychiatry 47(10):921–927

    Article  CAS  PubMed  Google Scholar 

  123. Lauderdale DS, Knutson KL, Yan LL et al (2006) Objectively measured sleep characteristics among early-middle-aged adults: the CARDIA study. Am J Epidemiol 164(1):5–16

    Article  PubMed  Google Scholar 

  124. Ertel KA, Berkman LF, Buxton OM (2011) Socioeconomic status, occupational characteristics, and sleep duration in African/Caribbean immigrants and US White health care workers. Sleep 34(4):509–518

    Article  PubMed Central  PubMed  Google Scholar 

  125. Hale L, Do DP (2007) Racial differences in self-reports of sleep duration in a population-based study. Sleep 30(9):1096–1103

    Article  PubMed Central  PubMed  Google Scholar 

  126. Nunes J, Jean-Louis G, Zizi F et al (2008) Sleep duration among black and white Americans: results of the National Health Interview Survey. J Natl Med Assoc 100(3):317–322

    Article  PubMed  Google Scholar 

  127. Stamatakis KA, Kaplan GA, Roberts RE (2007) Short sleep duration across income, education, and race/ethnic groups: population prevalence and growing disparities during 34 years of follow-up. Ann Epidemiol 17(12):948–955

    Article  PubMed Central  PubMed  Google Scholar 

  128. Whinnery J, Jackson N, Rattanaumpawan P, Grandner MA (2014) Short and long sleep duration associated with race/ethnicity, sociodemographics, and socioeconomic position. Sleep 37(3):601–611

    Article  PubMed Central  PubMed  Google Scholar 

  129. Knutson KL, Van Cauter E, Rathouz PJ et al (2009) Association between sleep and blood pressure in midlife: the CARDIA sleep study. Arch Intern Med 169(11):1055–1061

    Article  PubMed Central  PubMed  Google Scholar 

  130. Natal CL, Lourenco TJ, Silva LA et al (2009) Gender differences in the sleep habits of 11–13 year olds. Revista brasileira de psiquiatria. 31(4):358–361

    Article  PubMed  Google Scholar 

  131. Arber S, Bote M, Meadows R (2009) Gender and socio-economic patterning of self-reported sleep problems in Britain. Soc Sci Med 68(2):281–289

    Article  PubMed  Google Scholar 

  132. Rodriiguez-Munoz A, Moreno-Jimenez B, Fernandez-Mendoza JJ, Olavarrieta-Bernardino S, de la Cruz-Troca JJ, Vela-Bueno A (2008) [Insomnia and quality of sleep among primary care physicians: a gender perspective]. Revista de neurologia 47(3):119–123

    Google Scholar 

  133. Goel N, Kim H, Lao RP (2005) Gender differences in polysomnographic sleep in young healthy sleepers. Chronobiol Int 22(5):905–915

    Article  PubMed  Google Scholar 

  134. Bixler EO, Vgontzas AN, Lin HM, Vela-Bueno A, Kales A (2002) Insomnia in central Pennsylvania. J Psychosom Res 53(1):589–592

    Article  CAS  PubMed  Google Scholar 

  135. Zhang B, Wing YK (2006) Sex differences in insomnia: a meta-analysis. Sleep 29(1):85–93

    Article  PubMed  Google Scholar 

  136. Morrish E, Shneerson JM, Smith IE (2008) Why does gender influence survival in obstructive sleep apnoea? Respir Med 102(9):1231–1236

    Article  CAS  PubMed  Google Scholar 

  137. Johnson EO, Roth T, Schultz L, Breslau N (2006) Epidemiology of DSM-IV insomnia in adolescence: lifetime prevalence, chronicity, and an emergent gender difference. Pediatrics 117(2):e247–e256

    Article  PubMed  Google Scholar 

  138. Troxel WM, Buysse DJ, Matthews KA et al (2010) Marital/cohabitation status and history in relation to sleep in midlife women. Sleep 33(7):973–981

    Article  PubMed Central  PubMed  Google Scholar 

  139. Hale L (2005) Who has time to sleep? J Public Health (Oxf) 27(2):205–211

    Article  Google Scholar 

  140. Troxel WM, Buysse DJ, Hall M, Matthews KA (2009) Marital happiness and sleep disturbances in a multi-ethnic sample of middle-aged women. Behav Sleep Med 7(1):2–19

    Article  PubMed Central  PubMed  Google Scholar 

  141. Troxel WM, Cyranowski JM, Hall M, Frank E, Buysse DJ (2007) Attachment anxiety, relationship context, and sleep in women with recurrent major depression. Psychosom Med. Sep–Oct 69(7):692–699

    Article  Google Scholar 

  142. Wang X-S, Armstrong MEG, Cairns BJ, Key TJ, Travis RC (2011) Shift work and chronic disease: the epidemiological evidence. Occupational medicine 61(2):78–89

    Google Scholar 

  143. Frost P, Kolstad HA, Bonde JP (2009) Shift work and the risk of ischemic heart disease—a systematic review of the epidemiologic evidence. Scand J Work, Environ Health 35(3):163–179

    Google Scholar 

  144. Brown DL, Feskanich D, Sánchez BN, Rexrode KM, Schernhammer ES, Lisabeth LD (2009) Rotating night shift work and the risk of ischemic stroke. Am J Epidemiol 169(11):1370–1377

    Article  PubMed Central  PubMed  Google Scholar 

  145. Drake CL, Roehrs T, Richardson G, Walsh JK, Roth T (2004) Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. Sleep 27(8):1453–1462

    Google Scholar 

  146. Karlsson B, Knutsson A, Lindahl B (2001) Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 people. Occup Environ Med 58(11):747–752

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  147. Knutsson A, Boggild H (2010) Gastrointestinal disorders among shift workers. Scand J Work Environ Health 36(2):85–95

    Article  PubMed  Google Scholar 

  148. Hansen J (2006) Risk of breast cancer after night- and shift work: current evidence and ongoing studies in Denmark. Cancer Causes Control: CCC 17(4):531–537

    Article  PubMed  Google Scholar 

  149. Kubo T, Ozasa K, Mikami K et al (2006) Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study. Am J Epidemiol 164(6):549–555

    Article  PubMed  Google Scholar 

  150. Bushnell PT, Colombi A, Caruso CC, Tak S (2010) Work schedules and health behavior outcomes at a large manufacturer. Ind Health 48(4):395–405

    Article  PubMed  Google Scholar 

  151. Mahoney MM (2010) Shift work, jet lag, and female reproduction. Int J Endocrinol. 2010:813764

    Article  PubMed Central  PubMed  Google Scholar 

  152. Bonzini M, Palmer KT, Coggon D, Carugno M, Cromi A, Ferrario MM (2011) Shift work and pregnancy outcomes: a systematic review with meta-analysis of currently available epidemiological studies. BJOG: Int J Obstet Gynaecol 118(12):1429–1437

    Article  CAS  Google Scholar 

  153. Akerstedt T, Wright KP Jr (2009) Sleep loss and fatigue in shift work and shift work disorder. Sleep Med Clin 4(2):257–271

    Article  PubMed Central  PubMed  Google Scholar 

  154. Ohayon MM, Smolensky MH, Roth T (2010) Consequences of shiftworking on sleep duration, sleepiness, and sleep attacks. Chronobiol Int 27(3):575–589

    Article  PubMed  Google Scholar 

  155. Johnson AL, Brown K, Weaver MT (2010) Sleep deprivation and psychomotor performance among night-shift nurses. AAOHN J Off J Am Assoc Occup Health Nurses 58(4):147–154; quiz 155–146

    Google Scholar 

  156. Connor J, Norton R, Ameratunga S, et al (2002) Driver sleepiness and risk of serious injury to car occupants: population based case control study. BMJ 324(7346):1125

    Google Scholar 

  157. Dinges DF (1995) An overview of sleepiness and accidents. J Sleep Res 4(S2):4–14

    Article  CAS  PubMed  Google Scholar 

  158. Hublin C, Kaprio J, Partinen M, Koskenvuo M (2001) Insufficient sleep–a population-based study in adults. Sleep 24(4):392–400

    Article  CAS  PubMed  Google Scholar 

  159. Breslau N, Roth T, Rosenthal L, Andreski P (1997) Daytime sleepiness: an epidemiological study of young adults. Am J Public Health 87(10):1649–1653

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  160. Roehrs T, Merlotti L, Petrucelli N, Stepanski E, Roth T (1994) Experimental sleep fragmentation. Sleep 17(5):438–443

    Article  CAS  PubMed  Google Scholar 

  161. Roehrs T, Timms V, Zwyghuizen-Doorenbos A, Roth T (1989) Sleep extension in sleepy and alert normals. Sleep 12(5):449–457

    Article  CAS  PubMed  Google Scholar 

  162. Pack AI, Pack AM, Rodgman E, Cucchiara A, Dinges DF, Schwab CW. Characteristics of crashes attributed to the driver having fallen asleep. Accid Anal Prev 27(6):769–775

    Google Scholar 

  163. Leger D (1994) The cost of sleep-related accidents: a report for the national commission on sleep disorders research. Sleep 17(1):84–93

    Article  CAS  PubMed  Google Scholar 

  164. McCartt AT, Ribner SA, Pack AI, Hammer MC (1996) The scope and nature of the drowsy driving problem in New York State. Accid Anal Prev 28(4):511–517

    Article  CAS  PubMed  Google Scholar 

  165. Horne J, Reyner L (1999) Vehicle accidents related to sleep: a review. Occup Environ Med 56(5):289–294

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  166. Mitler MM, Carskadon MA, Czeisler CA, Dement WC, Dinges DF, Graeber RC (1988) Catastrophes, sleep, and public policy: consensus report. Sleep 11(1):100–109

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  167. Stutts JC, Wilkins JW (2003) Scott Osberg J, Vaughn BV. Driver risk factors for sleep-related crashes. Accid Anal Prev 35(3):321–331

    Article  PubMed  Google Scholar 

  168. Stoohs RA, Guilleminault C, Itoi A, Dement WC (1994) Traffic accidents in commercial long-haul truck drivers: the influence of sleep-disordered breathing and obesity. Sleep 17(7):619–623

    Google Scholar 

  169. McCartt AT, Rohrbaugh JW, Hammer MC, Fuller SZ (2000) Factors associated with falling asleep at the wheel among long-distance truck drivers. Accid Anal Prev 32(4):493–504

    Google Scholar 

  170. Lyznicki JM, Doege TC, Davis RM, Williams MA (1998) Sleepiness, driving, and motor vehicle crashes. Council on scientific affairs, american medical association. JAMA 279(23):1908–1913

    Article  CAS  PubMed  Google Scholar 

  171. Marcus CL, Loughlin GM (1996) Effect of sleep deprivation on driving safety in housestaff. Sleep 19(10):763–766

    Google Scholar 

  172. Steele MT, Ma OJ, Watson WA, Thomas HA Jr, Muelleman RL (1999) The occupational risk of motor vehicle collisions for emergency medicine residents. Acad Emer Med: Off J Soc Acad Emer Med 6(10):1050–1053

    Article  CAS  Google Scholar 

  173. Hastings MH, Reddy AB, Maywood ES (2003) A clockwork web: circadian timing in brain and periphery, in health and disease. Nat Rev Neurosci 4(8):649–661

    Google Scholar 

  174. Neri DF, Oyung RL, Colletti LM, Mallis MM, Tam PY, Dinges DF (2002) Controlled breaks as a fatigue countermeasure on the flight deck. Aviation, space, and environmental medicine 73(7):654–664

    Google Scholar 

  175. Price WJ, Holley DC (1990) Shiftwork and safety in aviation. Occup Med 5(2):343–377

    CAS  PubMed  Google Scholar 

  176. Bourgeois-Bougrine S, Carbon P, Gounelle C, Mollard R, Coblentz A (2003) Perceived fatigue for short- and long-haul flights: a survey of 739 airline pilots. Aviat Space Environ Med 74(10):1072–1077

    PubMed  Google Scholar 

  177. Dawson D, Reid K (1997) Fatigue, alcohol and performance impairment. Nature 388(6639):235

    Google Scholar 

  178. Fairclough SH, Graham R (1999) Impairment of driving performance caused by sleep deprivation or alcohol: a comparative study. Hum Factors 41(1):118–128

    Google Scholar 

  179. Williamson AM, Feyer AM (2000) Moderate sleep deprivation produces impairments in cognitive and motor performance equivalent to legally prescribed levels of alcohol intoxication. Occup Environ Med 57(10):649–655

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  180. Maia Q, Grandner MA, Findley J, Gurubhagavatula I (2013) Short and long sleep duration and risk of drowsy driving and the role of subjective sleep insufficiency. Accid Anal Prev 59:618–622

    Article  PubMed Central  PubMed  Google Scholar 

  181. Banks S, Dinges DF (2007) Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med 3(5):519–528

    PubMed Central  PubMed  Google Scholar 

  182. Grandner MA, Pack AI (2011) Sleep disorders, public health, and public safety. JAMA 306(23):2616–2617

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  183. Rosekind MR, Gregory KB, Mallis MM, Brandt SL, Seal B, Lerner D (2010) The cost of poor sleep: workplace productivity loss and associated costs. J Occup Environ Med 52(1):91–98

    Article  PubMed  Google Scholar 

  184. Grandner MA (2012) Sleep duration across the lifespan: implications for health. Sleep Med Rev 16(3):199–201

    Article  PubMed Central  PubMed  Google Scholar 

  185. Grandner MA, Patel NP, Gooneratne NS (2012) Difficulties sleeping: a natural part of growing older? Aging Health 8(3):219–221

    Article  CAS  Google Scholar 

  186. Grandner MA, Martin JL, Patel NP et al (2012) Age and sleep disturbances among american men and women: data from the U.S. Behavioral risk factor surveillance system. Sleep 35(3):395–406

    PubMed Central  PubMed  Google Scholar 

  187. Zee P (2009) Gender, age and the risk of insomnia. CNS Spectr 13(12 Suppl 17):7–9

    Google Scholar 

  188. Grandner MA, Petrov MER, Rattanaumpawan P, Jackson N, Platt A, Patel NP (2013) Sleep symptoms, race/ethnicity, and socioeconomic position. J Clin Sleep Med 9(9):897–905

    PubMed Central  PubMed  Google Scholar 

  189. Troxel WM, Germain A (2011) Insecure attachment is an independent correlate of objective sleep disturbances in military veterans. Sleep Med 12(9):860–865

    Article  PubMed Central  PubMed  Google Scholar 

  190. Troxel WM (2010) It’s more than sex: exploring the dyadic nature of sleep and implications for health. Psychosom Med 72(6):578–586

    Article  PubMed Central  PubMed  Google Scholar 

  191. Troxel WM, Buysse DJ, Monk TH, Begley A, Hall M (2010) Does social support differentially affect sleep in older adults with versus without insomnia? J Psychosom Res 69(5):459–466

    Article  PubMed Central  PubMed  Google Scholar 

  192. Williams S (2005) Sleep and society: sociological ventures into the (un)known. Taylor & Francis, London

    Google Scholar 

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Authors and Affiliations

  1. College of Medicine, University of Arizona, 1501 N. Campbell Avenue, AHSC Room 7326A, PO Box 245002, Tucson, AZ, 85724-5002, USA

    Michael A. Grandner

  2. Internal Medicine, The Wright Center for Graduate Medical Education, 501 Madison Avenue, Scranton, PA, 18510, USA

    Raza Mian

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  1. School of Graduate Medical Education, Seton Hall University, South Orange, New Jersey, USA

    Sudhansu Chokroverty

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Grandner, M.A., Mian, R. (2017). Effects of Sleep Deprivation and Sleepiness on Society and Driving. In: Chokroverty, S. (eds) Sleep Disorders Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-6578-6_4

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