Skip to main content

Uncertainty and Ambiguity in Health Decisions

  • Chapter
  • First Online:
Handbook of Health Decision Science

Abstract

Uncertainty is central to health decisions across the entire continuum of medical care—from disease prevention and screening, to disease treatment, to end-of-life care. For numerous decisions in all these domains, uncertainty is the omnipresent problem that makes decisions both possible and necessary. The current chapter provides an overview of important theoretical and empirical work on the effects of uncertainty in healthcare decisions. It first discusses the concept of uncertainty and provides a working definition to guide further analysis and discussion. It then reviews theory and evidence on the effects of one important type of uncertainty, known as “ambiguity” or “epistemic uncertainty,” on health decisions and patient well-being. The chapter puts forth the argument that ambiguity in healthcare decisions has important psychological effects that need to be better understood and accounted for, and suggests potentially fruitful directions for future research in this area.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Arlo-Costa, H., & Helzner, J. (2005). Comparative ignorance and the Ellsberg phenomenon. Paper presented at the 4th International Symposium on Imprecise Probabilities and their Applications.

    Google Scholar 

  • Beck, A. T., Emery, G., & Greenberg, R. C. (1986). Anxiety disorders and phobias: A cognitive perspective. New York: Guilford Press.

    Google Scholar 

  • Bier, V. M., & Connell, B. L. (1994). Ambiguity seeking in multi-attribute decisions: Effects of optimism and message framing. Journal of Behavioral Decision Making, 7, 169–182.

    Article  Google Scholar 

  • Budner, S. (1962). Intolerance of ambiguity as a personality variable. Journal of Personality, 30, 29–59.

    Article  PubMed  Google Scholar 

  • Buhr, K., & Dugas, M. (2002). Intolerance for uncertainty scale: Psychometric properties of the English version. Behaviour Research and Therapy, 40, 931–946.

    Article  PubMed  Google Scholar 

  • Cabantous, L. (2007). Ambiguity aversion in the field of insurance: Insurers’ attitude to imprecise and conflicting probability estimates. Theory and Decision, 62, 219–240.

    Article  Google Scholar 

  • Calvo, M. G., & Castillo, M. D. (1997). Mood-congruent bias in interpretation of ambiguity: Strategic processes and temporary activation. Quarterly Journal of Experimental Psychology, 50A(1), 163–182.

    Article  Google Scholar 

  • Camerer, C., & Weber, M. (1992). Recent developments in modeling preferences: Uncertainty and ambiguity. Journal of Risk and Uncertainty, 5, 325–370.

    Article  Google Scholar 

  • Chow, C. C., & Sarin, R. K. (2001). Comparative ignorance and the Ellsberg Paradox. Journal of Risk and Uncertainty, 22(2), 129–139.

    Article  Google Scholar 

  • Curley, S. P., & Yates, J. F. (1985). The center and range of the probability interval as factors affecting ambiguity preferences. Organizational Behavior and Human Decision Processes, 36, 273–287.

    Article  Google Scholar 

  • Curley, S. P., & Yates, J. F. (1989). An empirical evaluation of descriptive models of ambiguity reactions in choice situations. Journal of Mathematical Psychology, 33, 397–427.

    Article  Google Scholar 

  • Curley, S. P., Yates, J. F., & Abrams, R. A. (1986). Psychological sources of ambiguity avoidance. Organizational Behavior and Human Decision Processes, 38, 230–256.

    Article  Google Scholar 

  • Einhorn, H. J., & Hogarth, R. M. (1985). Ambiguity and uncertainty in probabilistic inference. Psychological Review, 92(4), 433–461.

    Article  Google Scholar 

  • Einhorn, H. J., & Hogarth, R. M. (1986). Decision making under ambiguity. Journal of Business, 59(4), S225–S250.

    Article  Google Scholar 

  • Ellsberg, D. (1961). Risk, ambiguity, and the savage axioms. Quarterly Journal of Economics, 75, 643–669.

    Article  Google Scholar 

  • Epstein, R. M., & Street, R. L. J. (2007). Patient-centered communication in cancer care: Promoting healing and reducing suffering (p. 07-6225). Bethesda, MD: NIH Publication.

    Google Scholar 

  • Fox, C. R., & Tversky, A. (1995). Ambiguity aversion and comparative ignorance. Quarterly Journal of Economics, 110, 585–603.

    Article  Google Scholar 

  • Fox, C. R., & Weber, M. (2002). Ambiguity aversion, comparative ignorance, and decision context. Organizational Behavior and Human Decision Processes, 88, 476–498.

    Article  Google Scholar 

  • Frewer, L. (2004). The public and effective risk communication. [Review]. Toxicology Letters, 149(1–3), 391–397.

    Article  PubMed  Google Scholar 

  • Frewer, L. J., Miles, S., Brennan, M., Kuznesof, S., Ness, M., & Ritson, C. (2002). Public preferences for informed choice under conditions of risk uncertainty. Public Understanding of Science, 11, 363–372.

    Article  Google Scholar 

  • Frisch, D., & Baron, J. (1988). Ambiguity and rationality. Journal of Behavioral Decision Making, 1, 149–157.

    Article  Google Scholar 

  • Frosch, D. L., Kaplan, R. M., & Felitti, V. J. (2003). A randomized controlled trial comparing internet and video to facilitate patient education for men considering the prostate specific antigen test. Journal of General Internal Medicine, 18(10), 781–787.

    Article  PubMed  PubMed Central  Google Scholar 

  • Furnham, A., & Ribchester, T. (1995). Tolerance of ambiguity: A review of the concept, its measurement and applications. Current Psychology, 14(3), 179–199.

    Article  Google Scholar 

  • Geller, G., Faden, R. R., & Levine, D. M. (1990). Tolerance for ambiguity among medical students: Implications for their selection, training and practice. Social Science and Medicine, 31(5), 619–624.

    Article  PubMed  Google Scholar 

  • Geller, G., Tambor, E. S., Chase, G. A., & Holtzman, N. A. (1993). Measuring physicians’ tolerance for ambiguity and its relationship to their reported practices regarding genetic testing. Medical Care, 31(11), 989–1001.

    Article  PubMed  Google Scholar 

  • Gerrity, M. S., DeVellis, R. F., & Earp, J. A. (1990). Physicians’ reactions to uncertainty in patient care. A new measure and new insights. Medical Care, 28(8), 724–736.

    Article  PubMed  Google Scholar 

  • Griffin, R. J., Dunwoody, S., & Neuwirth, K. (1999). Proposed model of the relationship of risk information seeking and processing to the development of preventive behaviors. [Research Support, Non-U.S. Gov’t]. Environmental Research, 80(2 Pt 2), S230–S245.

    Article  PubMed  Google Scholar 

  • Griffin, R. J., Neuwirth, K., Dunwoody, S., & Giese, J. (2004). Information sufficiency and risk communication. Media Psychology, 6, 23–61.

    Article  Google Scholar 

  • Gutscher, H., Earle, T., & Siegrist, M. (Eds.). (2012). Trust in cooperative risk management: Uncertainty and scepticism in the public mind. London: Routledge.

    Google Scholar 

  • Han, P. K., Klein, W. M., & Arora, N. K. (2011a). Varieties of uncertainty in health care: A conceptual taxonomy. An International Journal of the Society for Medical Decision Making, 31(6), 828–838.

    Article  Google Scholar 

  • Han, P. K., Klein, W. M., Lehman, T., Killam, B., Massett, H., & Freedman, A. N. (2011b). Communication of uncertainty regarding individualized cancer risk estimates: Effects and influential factors. [Research Support, N.I.H., Intramural]. An International Journal of the Society for Medical Decision Making, 31(2), 354–366.

    Article  Google Scholar 

  • Han, P. K., Kobrin, S. C., Klein, W. M., Davis, W. W., Stefanek, M., & Taplin, S. H. (2007a). Perceived ambiguity about screening mammography recommendations: Association with future mammography uptake and perceptions. Cancer Epidemiology Biomarkers and Prevention, 16(3), 458–466.

    Article  Google Scholar 

  • Han, P. K., Moser, R. P., & Klein, W. M. (2006). Perceived ambiguity about cancer prevention recommendations: Relationship to perceptions of cancer preventability, risk, and worry. Journal of Health Communication, 11(Suppl 1), 51–69.

    Article  PubMed  PubMed Central  Google Scholar 

  • Han, P. K., Moser, R. P., & Klein, W. M. (2007b). Perceived ambiguity about cancer prevention recommendations: Associations with cancer-related perceptions and behaviours in a US population survey. Health Expectations, 10(4), 321–336.

    Article  PubMed  PubMed Central  Google Scholar 

  • Han, P. K., Reeve, B. B., Moser, R. P., & Klein, W. M. (2009). Aversion to ambiguity regarding medical tests and treatments: Measurement, prevalence, and relationship to sociodemographic factors. Journal of Health Communication, 14(6), 556–572.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hazlett-Stevens, H., & Borkovec, T. D. (2004). Interpretive cues and ambiguity in generalized anxiety disorder. Behaviour Research and Therapy, 42(8), 881–892.

    Article  PubMed  Google Scholar 

  • Heath, C., & Tversky, A. (1991). Preference and belief: Ambiguity and competence in choice under uncertainty. Journal of Risk and Uncertainty, 4, 5–28.

    Article  Google Scholar 

  • Highhouse, S. (1994). A verbal protocol analysis of choice under ambiguity. J Economic Psychology, 15, 621–635.

    Article  Google Scholar 

  • Howard, R. A. (1988). Uncertainty about probability: A decision analysis perspective. Risk Analysis, 8(1), 91–98.

    Article  Google Scholar 

  • Johnson, B. B., & Slovic, P. (1995). Presenting uncertainty in health risk assessment: Initial studies of its effects on risk perception and trust. Risk Analysis, 15(4), 485–494.

    Article  PubMed  Google Scholar 

  • Kahn, B. E., & Sarin, R. K. (1988). Modeling ambiguity in decisions under uncertainty. Journal of Consumer Research, 15(2), 265–272.

    Article  Google Scholar 

  • Keren, G., & Gerritsen, L. E. M. (1999). On the robustness and possible accounts of ambiguity aversion. Acta Psychologica, 103, 149–172.

    Article  Google Scholar 

  • Klein, W. M. P., Cerully, J. L., Monin, M. M., & Moore, D. A. (2010). Ability, chance, and ambiguity aversion: Revisiting the competence hypothesis. Judgment and Decision Making, 5, 192–199.

    Google Scholar 

  • Kruglanski, A. W., & Webster, D. M. (1996). Motivated closing of the mind: “Seizing” and “freezing”. Psychological Review, 103(2), 263–283.

    Article  PubMed  Google Scholar 

  • Kuhberger, A., & Perner, J. (2003). The role of competition and knowledge in the Ellsberg task. Journal of Behavioral Decision Making, 16, 181–191.

    Article  Google Scholar 

  • Kuhn, K. M. (1997). Communicating uncertainty: Framing effects on responses to vague probabilities. Organizational Behavior and Human Decision Processes, 71(1), 55–83.

    Article  Google Scholar 

  • Kuhn, K. M., & Budescu, D. V. (1996). The relative importance of probabilities, outcomes, and vagueness in hazard risk decisions. Organizational Behavior and Human Decision Processes, 68(3), 301–317.

    Article  Google Scholar 

  • Ladouceur, R., Talbot, F., & Dugas, M. J. (1997). Behavioral expressions of intolerance of uncertainty in worry. Experimental findings. Behavior Modification, 21(3), 355–371.

    Article  PubMed  Google Scholar 

  • Lauriola, M., & Levin, I. P. (2001). Relating individual differences in attitude toward ambiguity to risky choices. Journal of Behavioral Decision Making, 14(2), 107–122.

    Article  Google Scholar 

  • Lawson, C., & MacLeod, C. (1999). Depression and the interpretation of ambiguity. Behaviour Research and Therapy, 37(5), 463–474.

    Article  PubMed  Google Scholar 

  • Lerner, J. S., & Keltner, D. (2000). Beyond valence: Toward a model of emotion-specific influences on judgement and choice. Cognition and Emotion, 14(4), 473–493.

    Article  Google Scholar 

  • Lerner, J. S., & Keltner, D. (2001). Fear, anger, and risk. Journal of Personality and Social Psychology, 81(1), 146–159.

    Article  PubMed  Google Scholar 

  • Leventhal, H., Brissette, I., & Leventhal, E. A. (2003). The common-sense model of self-regulation of health and illness. In L. D. Cameron & H. Leventhal (Eds.), The Self-regulation of health and illness behaviour (pp. 42–65). London: Routledge.

    Google Scholar 

  • MacLeod, C., & Cohen, I. L. (1993). Anxiety and the interpretation of ambiguity: A text comprehension study. Journal of Abnormal Psychology, 102(2), 238–247.

    Article  PubMed  Google Scholar 

  • Mathews, A. M., & MacLeod, C. (1994). Cognitive approaches to emotions and emotional disorders. Annual Review of Psychology, 45, 25–50.

    Article  PubMed  Google Scholar 

  • Miles, A., Voorwinden, S., Mathews, A., Hoppitt, L. C., & Wardle, J. (2009). Cancer fear and the interpretation of ambiguous information related to cancer. Cognition and Emotion, 23, 701–713.

    Article  Google Scholar 

  • Miller, S. M. (1987). Monitoring and blunting: Validation of a questionnaire to assess styles of information seeking under threat. Journal of Personality and Social Psychology, 52(2), 345–353.

    Article  PubMed  Google Scholar 

  • Morgan, G., Dowlatabadi, H., Henrion, M., Keith, D., Lempert, R., McBride, S., et al. (Eds.). (2009). Best practice approaches for characterizing, communicating, and incorporating scientific uncertainty in decision making. A Report by the U.S. Climate Change Science Program and the Subcommittee on Global Change Research (Synthesis and Assessment Product 5.2M). Washington, DC: National Oceanic and Atmospheric Administration, U.S. Climate Change Science Program.

    Google Scholar 

  • Politi, M. C., Clark, M. A., Ombao, H., Dizon, D., & Elwyn, G. (2011). Communicating uncertainty can lead to less decision satisfaction: A necessary cost of involving patients in shared decision making? Health Expectations, 14(1), 84–91.

    Article  PubMed  Google Scholar 

  • Pulford, B. D. (2009). Is luck on my side? Optimism, pessimism, and ambiguity aversion. The Quarterly Journal of Experimental Psychology (Hove), 62(6), 1079–1087.

    Article  Google Scholar 

  • Ritov, I., & Baron, J. (1990). Reluctance to vaccinate: Omission bias and ambiguity. Journal of Behavioral Decision Making, 3, 263–277.

    Article  Google Scholar 

  • Smithson, M. (1989). Ignorance and uncertainty: Emerging paradigms. New York: Springer.

    Book  Google Scholar 

  • Smithson, M. (1999). Conflict aversion: Preference for ambiguity versus conflict in sources and evidence. Organizational Behavior and Human Decision Processes, 79(3), 179–198.

    Article  PubMed  Google Scholar 

  • Sorrentino, R. M., Bobocel, D. R., Gitta, M. Z., Olson, J. M., & Hewitt, E. C. (1988). Uncertainty orientation and persuasion: Individual differences in the effects of personal relevance on social judgments. Journal of Personality and Social Psychology, 55(3), 357–371.

    Article  Google Scholar 

  • Trautman, S. T., Vielder, F. M., & Wakker, P. P. (2008). Causes of ambiguity aversion: Known versus unknown preferences. Journal of Risk and Uncertainty, 36, 225–243.

    Article  Google Scholar 

  • Viscusi, W. K. (1997). Alarmist decisions with divergent risk information. The Economic Journal, 107, 1657–1670.

    Article  Google Scholar 

  • Viscusi, W. K., & Chesson, H. (1999). Hopes and fears: The conflicting effects of risk ambiguity. Theory and Decision, 47, 157–184.

    Article  Google Scholar 

  • Viscusi, W. K., Magat, W. A., & Huber, J. (1991). Communication of ambiguous risk information. Theory and Decision, 31, 159–173.

    Article  Google Scholar 

  • Viscusi, W. K., Magat, W. A., & Huber, J. (1999). Smoking status and public responses to ambiguous scientific risk evidence. Southern Economic Journal, 66(2), 250–270.

    Article  Google Scholar 

  • Volk, R. J., Spann, S. J., Cass, A. R., & Hawley, S. T. (2003). Patient education for informed decision making about prostate cancer screening: A randomized controlled trial with 1-year follow-up. The Annals of Family Medicine, 1(1), 22–28.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Paul K. J. Han .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer Science+Business Media New York

About this chapter

Cite this chapter

Han, P.K.J. (2016). Uncertainty and Ambiguity in Health Decisions. In: Diefenbach, M., Miller-Halegoua, S., Bowen, D. (eds) Handbook of Health Decision Science. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3486-7_10

Download citation

Publish with us

Policies and ethics