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DTI in Neurosurgical Planning

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Abstract

While noninvasive and invasive cortical and subcortical electrophysiologic measurements for clinical mapping of brain function have been available for decades, multiple noninvasive techniques are now increasingly available for routine neurosurgical planning. These include cortical mapping using magnetoencephalography (MEG) and BOLD functional magnetic resonance imaging (fMRI) and subcortical mapping using diffusion-based methods such as diffusion tensor imaging (DTI). Intraoperative electrophysiologic mapping remains the gold standard for most applications, but limitations do exist including intraindividual and interindividual variability and inaccuracy from penetration of current; and thus, noninvasive mapping provides at least complementary information. This chapter reviews potential neurosurgical applications of DTI, important limitations of the technique in this context, and the practical aspects of using DTI in neurosurgical planning.

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Authors and Affiliations

  1. Neuroradiology Section, Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce St., Philadelphia, PA, 19104, USA

    Ronald L. Wolf MD, PhD & Paolo G. Nucifora MD, PhD

  2. Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland Medical Center, Baltimore, MD, USA

    Elias R. Melhem MD, PhD

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  1. Ronald L. Wolf MD, PhD
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  2. Paolo G. Nucifora MD, PhD
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  3. Elias R. Melhem MD, PhD
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Correspondence to Ronald L. Wolf MD, PhD .

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Editors and Affiliations

  1. icometrix; Department of Radiology, Department of Radiology, Antwerp University Hospital, Leuven, Antwerpen, Belgium

    Wim Van Hecke

  2. Departments of Translational MRI and Radiology, KU Leuven and University Hospitals Leuven, Leuven, Belgium

    Louise Emsell

  3. Departments of Translational MRI and Radiology, KU Leuven and University Hospitals Leuven, Leuven, Belgium

    Stefan Sunaert

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Wolf, R.L., Nucifora, P.G., Melhem, E.R. (2016). DTI in Neurosurgical Planning. In: Van Hecke, W., Emsell, L., Sunaert, S. (eds) Diffusion Tensor Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3118-7_14

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