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The Future of Erectile Dysfunction Therapy I: Implementation of Translational Research

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Management of Sexual Dysfunction in Men and Women

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Abstract

The treatment of erectile dysfunction (ED) was radically altered following the introduction of oral phosphodiesterase type 5 inhibitors and direct penile injections of vasoactive compounds. However, a large number of men have a poor response to these traditional treatments and require additional management strategies. Currently, novel, minimally invasive strategies are being developed with the hope of delaying placement of an inflatable penile prosthesis, which represents the final phase of ED treatment. This chapter examines the development and role of nanoparticles, the use of stem cells, tissue engineering, and gene therapy for the treatment of ED.

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Acknowledgments

JRK is an NIH K12 Scholar supported by a Male Reproductive Health Research Career (MRHR) Development Physician-Scientist Award (HD073917-01) from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Program.

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Authors and Affiliations

  1. Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA

    Michael Pan M.D.

  2. Urology of Indiana, 12188-A North Meridian Street, Suite 200, Carmel, IN, 46032, USA

    Jason R. Kovac M.D., Ph.D.

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  1. Michael Pan M.D.
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Correspondence to Jason R. Kovac M.D., Ph.D. .

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Editors and Affiliations

  1. Chief, Division of Male Reproductive Medicine and Surgery; Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA

    Larry I. Lipshultz

  2. Assistant Professor; Division of Male Reproductive Medicine and Surgery; Center for Reproductive Medicine; Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA

    Alexander W. Pastuszak

  3. Department of Obstetrics and Gynecology; George Washington University; School of Medicine and Health Sciences, The Center for Vulvovaginal Disorders, Washington, District of Columbia, USA

    Andrew T. Goldstein

  4. Psychiatric Center Copenhagen; Institute of Clinical Medicine; University of Copenhagen, Sexological Clinic, Copenhagen, Denmark

    Annamaria Giraldi

  5. Weill Medical College Cornell University; Co-Director, Human Sexuality Program; The New York Presbyterian Hospital; Founder, MAP Education and Research Fund, Clinical Professor of Psychiatry, Reproductive Medicine and Urology, NEW YORK, New York, USA

    Michael A. Perelman

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Pan, M., Kovac, J.R. (2016). The Future of Erectile Dysfunction Therapy I: Implementation of Translational Research. In: Lipshultz, L., Pastuszak, A., Goldstein, A., Giraldi, A., Perelman, M. (eds) Management of Sexual Dysfunction in Men and Women. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3100-2_11

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