Effects of Low Volume Aerobic Training on Muscle Desaturation During Exercise in Elderly Subjects

  • Shun TakagiEmail author
  • Ryotaro Kime
  • Norio Murase
  • Masatsugu Niwayama
  • Takuya Osada
  • Toshihito Katsumura
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 876)


Aging enhances muscle desaturation responses due to reduced O2 supply. Even though aerobic training enhances muscle desaturation responses in young subjects, it is unclear whether the same is true in elderly subjects. Ten elderly women (age: 62 ± 4 years) participated in 12-weeks of cycling exercise training. Training consisted of 30 min cycling exercise at the lactate threshold. The subjects exercised 15 ± 6 sessions during training. Before and after endurance training, the subjects performed ramp cycling exercise. Muscle O2 saturation (SmO2) was measured at the vastus lateralis by near infrared spectroscopy during the exercise. There were no significant differences in SmO2 between before and after training. Nevertheless, changes in peak pulmonary O2 uptake were significantly negatively related to changes in SmO2 (r = −0.67, p < 0.05) after training. Muscle desaturation was not enhanced by low volume aerobic training in this study, possibly because the training volume was too low. However, our findings suggest that aerobic training may potentially enhance muscle desaturation at peak exercise in elderly subjects.


Aging Cycling training Muscle oxygen saturation Near infrared spectroscopy Peak aerobic capacity 



The authors are grateful for revision of this manuscript by Andrea Hope. This study was supported in part by Grant-in-Aid for scientific research from Japan Society for the Promotion of Science (246298) to S.T. and Waseda University Grant for Special Research Projects (2014S-148) to S.T.


  1. 1.
    Kime R, Niwayama M, Fujioka M et al (2010) Unchanged muscle deoxygenation heterogeneity during bicycle exercise after 6 weeks of endurance training. Adv Exp Med Biol 662:353–358CrossRefPubMedGoogle Scholar
  2. 2.
    Takagi S, Kime R, Murase N et al (2013) Aging affects spatial distribution of leg muscle oxygen saturation during ramp cycling exercise. Adv Exp Med Biol 789:157–162CrossRefPubMedGoogle Scholar
  3. 3.
    Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60(6):2020–2027PubMedGoogle Scholar
  4. 4.
    Wasserman K, Whipp BJ, Koyl SN (1973) Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol 35(2):236–243PubMedGoogle Scholar
  5. 5.
    Niwayama M, Suzuki H, Yamashita T et al (2012) Error factors in oxygenation measurement using continuous wave and spatially resolved near-infrared spectroscopy. J Jpn Coll Angiol 52:211–215CrossRefGoogle Scholar
  6. 6.
    Mezzani A, Grassi B, Jones AM et al (2013) Speeding of pulmonary VO2 on-kinetics by light-to-moderate-intensity aerobic exercise training in chronic heart failure: clinical and pathophysiological correlates. Int J Cardiol 167(5):2189–2195CrossRefPubMedGoogle Scholar
  7. 7.
    Kime R, Osada T, Shiroishi K et al (2006) Muscle oxygenation heterogeneity in a single muscle at rest and during bicycle exercise. Jpn J Phys Fit Sports Med 55(Suppl):S19–S22CrossRefGoogle Scholar
  8. 8.
    Takagi S, Murase N, Kime R et al (2014) Skeletal muscle deoxygenation abnormalities in early post myocardial infarction. Med Sci Sports Exerc 46(11):2062–2069 doi: 10.1249/MSS.0000000000000334
  9. 9.
    Saltin B, Radegran G, Koskolou MD et al (1998) Skeletal muscle blood flow in humans and its regulation during exercise. Acta Physiol Scand 162:421–436CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, New York 2016

Authors and Affiliations

  • Shun Takagi
    • 1
    • 2
    Email author
  • Ryotaro Kime
    • 2
  • Norio Murase
    • 2
  • Masatsugu Niwayama
    • 3
  • Takuya Osada
    • 2
  • Toshihito Katsumura
    • 2
  1. 1.Faculty of Sport SciencesWaseda UniversityTokorozawaJapan
  2. 2.Department of Sports Medicine for Health PromotionTokyo Medical UniversityShinjukuJapan
  3. 3.Department of Electrical and Electronic EngineeringShizuoka UniversityHamamatsuJapan

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