Impact of Oxygenation Status on 18F-FDG Uptake in Solid Tumors
The influence of changes in tumor oxygenation (monitored by EPR oximetry) on the uptake of 18F-FDG tracer was evaluated using micro-PET in two different human tumor models. The 18F-FDG uptake was higher in hypoxic tumors compared to tumors that present a pO2 value larger than 10 mmHg.
KeywordsEPR 18F-FDG PET Carbogen Tumor oxygenation
This study was supported by grants from the Belgian National Fund for Scientific Research (FNRS).
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