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Comparison of Cerebral Oxygen Saturation and Cerebral Perfusion Computed Tomography in Cerebral Blood Flow in Patients with Brain Injury

  • Alexey O. TrofimovEmail author
  • George Kalentiev
  • Oleg Voennov
  • Vera Grigoryeva
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 876)

Abstract

The purpose of this study was to determine the relationship between cerebral tissue oxygen saturation and cerebral blood volume in patients with traumatic brain injury. Perfusion computed tomography of the brain was performed in 25 patients with traumatic brain injury together with simultaneous SctO2 level measurement using cerebral near-infrared oxymetry. The mean age of the injured persons was 34.5 ± 15.6 years (range 15–65); 14 men, 11 women. The Injury Severity Score (ISS) values were 44.4 ± 9.7 (range 25–81). The Glasgow Coma Score (GCS) mean value before the study was 10.6 ± 2.1 (range 5–13). SctO2 ranged from 51 to 89 %, mean 62 ± 8.2 %. Cerebral blood volume (CBV) values were 2.1 ± 0.67 ml/100 g (min 1.1; max 4.3 ml/100 g). Cerebral blood flow (CBF) was 31.99 ± 13.6 ml/100 g × min. Mean transit time (MTT) values were 5.7 ± 4.5 s (min 2.8; max 34.3 s). The time to peak (TTP) was 22.2 ± 3.1 s. A statistically significant correlation was found between SctO2 level and cerebral blood volume (CBV) level (R = 0.9; p < 0.000001). No other significant correlations were found between brain tissue oxygenation and other parameters of brain perfusion.

Keywords

Head injury NIRS Perfusion CT 

References

  1. 1.
    Taussky P (2012) Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood. Neurosurg Focus 32:1–6CrossRefGoogle Scholar
  2. 2.
    Hoeffner E, Case I, Jain R (2004) Cerebral perfusion CT: technique and clinical applications. Radiology 231:632–644CrossRefPubMedGoogle Scholar
  3. 3.
    Wintermark M, Albers G, Alexandrov A (2008) Acute stroke imaging research roadmap. Am J Neuroradiol 29:23–30CrossRefGoogle Scholar
  4. 4.
    Constantoyannis C, Sakellaropoulos G (2007) Transcranial cerebral oximetry and transcranial doppler sonography in patients with ruptured cerebral aneurysms and delayed cerebral vasospasm. Med Sci Monit 13(10):35–40Google Scholar
  5. 5.
    Potapov A, Kornienko V, Zakharova N (2012) Peculiarities of regional cerebral blood flow, indices of intracranial and cerebral perfusion pressure in case of severe brain injury. Radio Diagn Ther 3:79–92Google Scholar

Copyright information

© Springer Science+Business Media, New York 2016

Authors and Affiliations

  • Alexey O. Trofimov
    • 1
    Email author
  • George Kalentiev
    • 1
  • Oleg Voennov
    • 1
  • Vera Grigoryeva
    • 1
  1. 1.Department of NeurosurgeryNizhniy Novgorod State Medical AcademyNizhniy NovgorodRussia

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