Abstract
The first decade of the twenty-first century brought significant changes, and a more stable fiscal outlook, to the MDIBL. It became clear early in the decade that the time had come for real strategic planning, including resurrecting a year-round research program with the potential of having a year-round Director on site. The fund-raising campaign associated with the Centennial had raised significant dollars (and partially paid for the new Conference Center), but it was clear that continued fiscal health and plans for expansion of the research program and administration would require very substantial increases in extramural funding, at the individual, state, and federal levels. Initial success came, after heavy lobbying in Maine’s capital by MDIBL administrators, with a grant from the Maine State Technology Foundation for a DNA Sequencing Center at the Laboratory, followed by other significant state bond issues that generated nearly $5M for the MDIBL. In addition and thanks to a very strategic hire of a new Administrative Director, the Laboratory was able to secure multimillion dollar NIH grants (BRIN then INBRE) to coordinate research and teaching throughout the state and support significant expansion of the administration of the Laboratory and a year-round research program by the end of the decade. A new, three-story research building was built with significant donated funds and a bank loan, after the NIH was unable to provide funds. However, the American Recovery and Reimbursement Act of 2009 provided funds for a second building, which was constructed after 2010. Two new dormitories, Spruce and Birch Halls, were also built during this period, using grants from NSF and significant donations from two Investigator families. The successful fund-raising, state bond issues, and significant overhead return from the BRIN/INBRE grants provided funds for the hiring of a cadre of year-round Investigators, as well as the first year-round Director by the end of the decade.
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Notes
- 1.
Minutes of the Meeting of the Board of Trustees, November 16, 1998, p. 1
- 2.
Ibid.
- 3.
Minutes of the Meeting of the Board of Trustees, November 16, 1998, p. 2
- 4.
Op. Cit., p. 3
- 5.
Ibid. As noted in Chap. 11, the Maren Auditorium had been constructed with a $250,000 donation from Tom and Emily Maren and a $200,000 construction loan from the First National Bank of Bar Harbor.
- 6.
Minutes of the Meeting of the Board of Trustees, November 16, 1998, p. 3
- 7.
This shortfall was recalculated to be $17,000 by the meeting the next spring (Minutes of the Meeting of the Meeting of the Board of Trustees, April 17, 1999, p. 2).
- 8.
Op. Cit., pp. 3–4
- 9.
The LRPC had proposed that the Laboratory needed to develop “a master plan to establish a year-round scientific presence within the next four years” at the Trustees meeting the previous July (Minutes of the Annual Trustees’ Meeting, July 23, 1998, p. 2).
- 10.
This would actually come to pass in 2014.
- 11.
Minutes of the Meeting of the Board of Trustees, November 16, 1998, p. 4. Thus, after years of prodding by Bodil Schmidt-Nielsen, Rolf Kinne, and others, the Board of Trustees of the MDIBL made a firm commitment to at least develop the plans necessary to implement a year-round scientific program, with a full-time, resident Director. The Laboratory was entering its twenty-first century and its future, but it would take another decade for a year-round Director to arrive.
- 12.
Minutes of the Meeting of the Board of Trustees, November 16, 1998, pp. 4–5
- 13.
Op. Cit., p. 5
- 14.
Ibid.
- 15.
Ibid. The inquiry must have led to the expected response, because Senator Goldthwait never served on the Board of Trustees. She did, however, present the keynote address at the 2001 Annual Corporation Meeting, and, as long-term resident of Bar Harbor, now former Senator Goldthwait remains a friend and supporter of the Laboratory.
- 16.
Minutes of the Meeting of the Board of Trustees, April 17, 1999, p. 1
- 17.
Op. Cit., p. 2
- 18.
Op. Cit., pp. 3–4. Unfortunately, there was never any complete resolution of this problem, so the air-conditioning system still makes more noise than expected.
- 19.
Minutes of the Meeting of the Board of Trustees, April 17, 1999, p. 4
- 20.
The Laboratory intended to apply to the State of Maine’s Science and Technology Fund for half of these costs.
- 21.
This was projected for Lewis, Halsey, and Forster laboratories, but the Laboratory intended to apply to the NSF for matching funds.
- 22.
Minutes of the Meeting of the Board of Trustees, April 17, 1999, p. 5
- 23.
Ibid.
- 24.
Signal transduction pathways are protein-based pathways (cell membrane receptors, enzymes, etc.) that transduce extracellular signals (toxins, hormones, neurotransmitters, etc.) into cellular responses. This had been a focus of the MDIBL in general for generations, as had the transport of solutes across cellular membranes. Xenobiotics are foreign chemicals that are not normally found in cells. Pharmaceuticals are xenobiotics, as are environmental pollutants. See: http://en.wikipedia.org/wiki/Xenobiotic).
- 25.
Minutes of the Meeting of the Board of Trustees, April 17, 1999, pp. 5–6
- 26.
Op. Cit., p. 6
- 27.
Op. Cit., pp. 6–7
- 28.
Op. Cit., pp. 7–8
- 29.
Op. Cit., p. 8
- 30.
Ibid.
- 31.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, pp. 2 and 8–10
- 32.
It also included short obituaries for Roy Forster and Carl Gottschalk (who had passed away in 1997).
- 33.
The new website for the Bulletin (with issues starting in 1997) had been designed and implemented by J. B. Claiborne and is available currently at http://mdibl.org/research/visiting/bulletin/.
- 34.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, p. 2
- 35.
Op. Cit. pp. 2–3
- 36.
Op. Cit., p. 3
- 37.
Towle had been a summer Investigator since 1983.
- 38.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, pp. 3–4. Clearly the onset of the molecular era at the MDIBL was having major consequences for the inventory of equipment necessary for suitable studies at the Laboratory.
- 39.
The dormitory was named after Spruce Point, where the Lewis Cottage was built in the early 1930s (on the old McCagg Tract; see Chap. 3) and still stands.
- 40.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, p. 4
- 41.
Ibid.
- 42.
Op. Cit., p. 5. MDIBL’s boundaries were/are extensive, so encroachment from neighbors, fishermen, and winter residents of MDI has been a routine for 90 years since the Laboratory came to Salisbury Cove. This would be the last recorded report from this Committee, which no longer exists.
- 43.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, p. 5
- 44.
This week-long course, as well as one for the University of Pittsburgh medical students, is still given each year in late May or early June. See http://mdibl.org/education/courses/.
- 45.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, p. 5
- 46.
Director’s Report, 1999, p. 1
- 47.
Fran Van Dolah, from the University of South Carolina, had hosted a workshop on “Advances in Detection Methods for Fungal and Algal Toxins” and Simon Watkins, from the University of Pittsburgh, had led a course in quantitative fluorescence microscopy, which had been taught by six faculty members (three MDIBL Investigators) and attracted 24 students and 14 industrial faculty members, who had brought over $3 million in equipment for the course. The QFM course is still offered each May at the MDIBL.
- 48.
Director’s Report, 1999, p. 2
- 49.
Op. Cit., pp. 2–3
- 50.
Op. Cit., p. 3
- 51.
Minutes of the Annual Meeting of the Corporation, July 22, 1999, pp. 6–7
- 52.
Op. Cit., p. 7
- 53.
Ibid. The Pot and Kettle Club, on the shore between Salisbury Cove and Hull’s Cove, is a venerable, and very private, men’s club that had been organized in approximately 1900. (See http://query.nytimes.com/mem/archive-free/pdf?res=F2081FFE345417738DDDA90B94DE405B878CF1D3 for a 1907 New York Times article about the club, which notes a visitor, Dr. S. Weir Mitchell, whose name was initially given to the tract of land on which the MDIBL now resides—see Chap. 2.)
- 54.
Minutes of the Annual Meeting of the Board of Trustees, July 22, 1999, pp. 1–2
- 55.
This was, in fact, the first $1 million pledge the MDIBL had ever received.
- 56.
Minutes of the Annual Meeting of the Board of Trustees, July 22, 1999, p. 2
- 57.
Op. Cit., p. 3
- 58.
Ibid.
- 59.
Ibid. Krogh, the father of MDIBL’s Bodil Schmidt-Nielsen and a Nobel Laureate (1920), had first iterated his famous principle in (Krogh 1929). (See also http://en.wikipedia.org/wiki/Krogh's_principle.)
- 60.
Minutes of the Annual Meeting of the Board of Trustees, July 22, 1999, pp. 3–4
- 61.
Op. Cit., p. 4
- 62.
Op. Cit., pp. 4–5
- 63.
Op. Cit., pp. 5–6
- 64.
Op. Cit., p. 6
- 65.
Rall’s legacy was the Toxicology Center (CMTS) at the MDIBL, because he had initiated the Marine and Freshwater Biomedical Science Centers when he was Director of the NIEHS. (See Chap. 7.)
- 66.
LaCasse brought mathematical, business, and personal skills to the Business Office that allowed the timely control and expansion of the MDIBL’s income/expense reporting that took place over the next decade.
- 67.
Minutes of the Meeting of the Board of Trustees, November 30, 1999, p. 1
- 68.
Op. Cit., p. 2
- 69.
Op.Cit., pp. 2–3
- 70.
Op. Cit., p. 3
- 71.
Op. Cit., p. 2
- 72.
Op. Cit., p. 3
- 73.
Ibid.
- 74.
Benz actually proposed the following goal statement: “Our overarching goal is to establish the MDIBL as the international center for excellence for the functional genomics of marine organisms and its application to human health. This excellence will be expressed through basic ad applied research, educational activities, conferences, and programs that foster interchange and collaboration among diverse groups of scholars and learners representing the relevant disciplines to achieve this goal.”
- 75.
Minutes of the Meeting of the Board of Trustees, November 30, 1999, pp. 3–4
- 76.
Op. Cit., p. 4
- 77.
Ibid.
- 78.
Ibid.
- 79.
Op.Cit., pp. 4–5
- 80.
Smith had been a Research Fellow in Jim Boyer’s lab in the 1980s.
- 81.
Minutes of the Meeting of the Board of Trustees, April 8, 2000, p. 1
- 82.
Op. Cit., pp. 1–2
- 83.
Op. Cit., pp. 2–3
- 84.
Op. Cit., p. 3. Towle would become, therefore, the first of the new cadre of year-round Investigators that was being recruited to the MDIBL.
- 85.
Minutes of the Meeting of the Board of Trustees, April 8, 2000, p. 3. Miller had come to the MDIBL as Bill Kinter’s postdoctoral fellow in the 1970s and has continued to work at the Laboratory most summers since.
- 86.
Minutes of the Meeting of the Board of Trustees, April 8, 2000, p. 3
- 87.
Op. Cit., pp. 3–4
- 88.
Even an evening with past and current Directors was auctioned off (Fig. 13.1).
- 89.
Op. Cit., p. 4
- 90.
Op. Cit., p. 5
- 91.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, p. 2
- 92.
There had actually been a net negative balance of income vs. expenses of nearly $20,000, but funds had been transferred into the operating budget from the endowment (Minutes of the Annual Meeting of the Corporation, July 27, 2000, p. 10).
- 93.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, p. 2
- 94.
To the consternation of long-time members of the Corporation, the more sophisticated accounting of the Laboratory’s finances provided a more opaque statement about income vs. expense for various aspects of the operation, viz., laboratory and cottage rental, dining hall, specimen collecting, etc. Thus, there was no way for MDIBL Investigators to gauge the fiscal status of various “cost centers” as they had in the past years.
- 95.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, pp. 2 and 8–10
- 96.
Op. Cit., pp. 3–4
- 97.
Op. Cit., pp. 4–5
- 98.
As he had shared with the Trustees earlier, this Nonprofit Biomedical Research Coalition had included MDIBL, Jackson Laboratory, Foundation for Blood Research, Maine Medical Center, and the University of Maine.
- 99.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, pp. 5–6. Starting in 2000, the Director’s Report was no longer printed as a separate part of the yearly Corporation Minutes, as it had been for the previous five decades.
- 100.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, p. 6. Forrest then projected a photo of the author’s new grandson (born July 14) asleep in his grandfather’s lap. Forrest had begun the tradition of presenting the Director’s Report using Microsoft’s PowerPoint.
- 101.
In 2000, the federal and private initiatives to sequence the human genome were still underway and relatively controversial. (See http://en.wikipedia.org/wiki/Human_Genome_Project and http://www.genome.gov/12011238.)
- 102.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, pp. 6–7. The content and tone of this first keynote address by a Laboratory PI suggests, correctly, that the Annual Meeting was evolving into a development event. Since the 1930s, the Annual Meeting of the MDIBL Corporation was largely attended by PIs and their spouses and intended to be a “town meeting” to hear what was going on and examine (and discuss in great detail) the yearly budget. It was now becoming an event, for promoting the Laboratory to the public and potential donors.
- 103.
Minutes of the Annual Meeting of the Corporation, July 27, 2000, p. 7
- 104.
Minutes of the Annual Meeting of the Board of Trustees, July 27, 2000, p. 1
- 105.
The Maren Foundation was also providing $50,000 per year during the initial years when the SCRF was growing.
- 106.
Op. Cit., pp. 1–2. As one might expect, this proviso has become increasingly difficult over the ensuing 15 years, since research interests and approaches have changed drastically in the early twenty-first century, as has the MDIBL’s ability to recruit Investigators with a particular research program.
- 107.
Minutes of the Annual Meeting of the Board of Trustees, July 27, 2000, p. 2
- 108.
Op. Cit., p. 3
- 109.
Ibid.
- 110.
Op. Cit., pp. 3–4
- 111.
Op. Cit., p. 4
- 112.
Ibid.
- 113.
Op. Cit., p. 5
- 114.
Minutes of the Meeting of the Board of Trustees, November 18, 2000, p. 1. After receiving her Ph.D. from George Washington University, Dr. Hand had been a Research Associate in the Laboratory of Viral Carcinogenesis of the National Cancer Institute and Research Scientist in the Laboratory of Cellular and Molecular Biology and then Laboratory of Tumor Immunology and Biology of the NCI from 1980 to 1998. For the two years before coming to the MDIBL, she had served as the Scientific Review Administrator in the Oncological Sciences Initial Review Group at the NIH.
- 115.
Minutes of the Meeting of the Board of Trustees, November 18, 2000, pp. 1–2
- 116.
Op. Cit., p. 2
- 117.
The BRIN Program was part of the NIH EPSCoR program which, like its counterpart at the NSF (which had funded the MDIBL previously; see Chap. 10), was intended to provide funding for collaborative research among institutions in states which had not been successful in securing their fair share of federal funding. The specifics will be discussed later in this chapter.
- 118.
Minutes of the Meeting of the Board of Trustees, November 18, 2000, pp. 2–3
- 119.
Op. Cit., p. 3
- 120.
Op. Cit., pp. 3–4
- 121.
Op. Cit., pp. 4–5
- 122.
Minutes of the Meeting of the Board of Trustees, April 7, 2001, p. 1
- 123.
Op. Cit., p. 2
- 124.
Op. Cit., pp. 2–3
- 125.
Op. Cit., p. 3. This was an entirely new development effort by the MDIBL; we will soon see how very successful this was. In fact, the funding that would come from this effort provided the foundation with the extraordinary expansion of the MDIBL during the first decade of the twenty-first century.
- 126.
Minutes of the Meeting of the Board of Trustees, April 7, 2001, p. 3
- 127.
Op. Cit., p. 4
- 128.
Minutes of the Meeting of the Board of Trustees, April 7, 2001, p. 4
- 129.
Ibid.
- 130.
Op.Cit., pp. 4–5
- 131.
Op. Cit., p. 5
- 132.
Minutes of the Annual Meeting of the Corporation, July 26, 2001, p. 2
- 133.
Op. Cit., pp. 17–18; compare with Minutes of the Annual Meeting of the Corporation, July 27, 2000, pp. 8–10. Although Jim McFarland had been pleased with the new format, most of the members of the Corporation, who were used to a more logical (and less formal) presentation, were confused.
- 134.
Minutes of the Annual Meeting of the Corporation, July 26, 2001, pp. 2–3
- 135.
Op. Cit., pp. 4–5
- 136.
Op. Cit., pp. 5–6
- 137.
Op. Cit. pp. 7–8
- 138.
As outlined in Forrest’s earlier reports for the year and the report by Patricia Hand, so they will not be repeated here.
- 139.
Minutes of the Annual Meeting of the Corporation, July 26, 2001, pp. 8–9
- 140.
Op. Cit., p. 9
- 141.
Op. Cit., p. 10
- 142.
Op. Cit., pp. 10–11
- 143.
Op. Cit., p. 12
- 144.
Ibid.
- 145.
Goldthwait, an RN, had worked in the emergency room at MDI hospital and served on and chaired the Bar Harbor Town Council for nine years, before serving four terms in the Maine Senate. She was Chair of the Appropriations Committee.
- 146.
Minutes of the Annual Meeting of the Corporation, July 26, 2001, pp. 13–14
- 147.
Op. Cit., pp. 14–16
- 148.
Op. Cit., pp. 16–17
- 149.
Op. Cit., p. 17
- 150.
Minutes of the Annual Meeting of the Corporation, July 26, 2001, pp. 1–2
- 151.
Op. Cit., p. 2
- 152.
Op. Cit., p. 3
- 153.
Op. Cit., p. 4
- 154.
Op. cit., p. 5. At the Director’s party, tribute was paid to Ray and Barbara Rappaport for their 52 years at the MDIBL by naming the old Union Station Laboratory (which Ray had designed) the Rappaport Laboratory.
- 155.
Minutes of the Meeting of the Board of Trustees, December 8, 2001, pp. 1–2
- 156.
Minutes of the Meeting of the Board of Trustees, December 8, 2001, pp. 2–3
- 157.
Op. Cit., p. 3
- 158.
Op. Cit., p. 4. Since the Board of Trustees had added nonscientist members and strengthened its position with the administrative restructuring in the late 1990s, the Board had started to want more control of the budget and administration of the Laboratory. The minutes of the 2002 meeting of the Board show the increasing tension that was developing between the new members of the Board and the scientific administration of the MDIBL.
- 159.
Minutes of the Meeting of the Board of Trustees, December 8, 2001, p. 5
- 160.
Ibid.
- 161.
Ibid.
- 162.
Op. Cit., p. 6
- 163.
Minutes of the Meeting of the Board of Trustees, April 6, 2001, p. 1
- 164.
Phoebe Boyer, Jr., eldest daughter of Jim and Phoebe Boyer, would soon join the Board of Trustees.
- 165.
Minutes of the Meeting of the Board of Trustees, April 6, 2001, pp. 1–2
- 166.
Op. Cit., p. 2
- 167.
Op. Cit., p. 3
- 168.
Op. Cit., p. 4
- 169.
Op. Cit., pp. 4–5
- 170.
Op. Cit., p. 5
- 171.
Op. Cit., pp. 5–6
- 172.
Op. Cit., p. 6
- 173.
Ibid.
- 174.
Minutes of the Annual Meeting of the Corporation, July 25, 2002, p. 2
- 175.
Op. Cit., pp. 3 and 24–25
- 176.
Op. Cit., p. 4
- 177.
A retired banker, Opdyke was the son of Dr. David Opdyke, who had worked at the MDIBL from the late 1960s to the middle 1990s.
- 178.
Minutes of the Annual Meeting of the Corporation, July 25, 2002, pp. 4–5; Mattingly’s research will be introduced in the next chapter.
- 179.
Op. Cit., p. 6
- 180.
Op. Cit., pp. 6–8
- 181.
Op. Cit., p. 8
- 182.
Birch Hall, another new dormitory had been built in 2002, with a new construction grant from the NSF and substantial donations from the Claiborne family, in memory of Eloise Claiborne, mother of long-time MDIBL PI, J. B. Claiborne (Fig. 13.7).
- 183.
Minutes of the Annual Meeting of the Corporation, July 25, 2002, pp. 8–10
- 184.
Barnes and Sato had been Director and Associate Director, respectively, of the National Stem Cell Resource at the American Type Culture Collection (ATCC) in Manassas, VA. They will be introduced in the next chapter.
- 185.
Minutes of the Annual Meeting of the Corporation, July 25, 2002, pp. 10–12
- 186.
Op. Cit., p. 13
- 187.
Op. Cit., pp. 13–14. From this and previous statements, it was clear that Forest and other members of the MDIBL community were increasingly concerned about the potential strain between the necessary evolution of the science, administration, and culture of the Laboratory and the established traditions of the institution.
- 188.
Minutes of the Annual Meeting of the Corporation, July 25, 2002, p. 14
- 189.
Op. Cit., pp. 14–23. The address was comprehensive and detailed, so only a very brief overview of topic headings has been given, in the interest of space.
- 190.
Minutes of the Annual Meeting of the Corporation, July 25, 2002, pp. 23–24
- 191.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, pp. 1–2
- 192.
Op. Cit., pp. 2–3
- 193.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, pp. 4–5. It is clear from this presentation that, now that many of their past suggestions were contained in the new Strategic Plan and the DAC had taken over many of their advisory functions, the Long Range Planning Committee was seeking a new role in the governance of the MDIBL.
- 194.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, p. 5
- 195.
Op. Cit., p. 6
- 196.
Op. Cit., pp. 6–7
- 197.
Op. Cit., p. 7
- 198.
The problem had been that the bond issue had been “highly criticized because it was loaded with everything from home security to highway improvements.” The Bar Harbor Times “was quoted as saying ‘vote for #2, but hold your nose.’” Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, p. 10.
- 199.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, pp. 7–9. In 2000, the Board had set a goal of raising $800,000 from its members, 20 % of the campaign goal. To date, it had only raised $371,000 in gifts and pledges.
- 200.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, pp. 8–9
- 201.
Op. Cit., p. 9
- 202.
Op. Cit., p. 10. This was the beginning of a process that would result, in less than a decade, in the initial funding of what is now the Kathryn W. Davis Center for Regenerative Biology and Medicine.
- 203.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, pp. 10–11
- 204.
Op. Cit., pp. 11–13. A notable exception was the University of Florida, which made approximately $8 M per year until the patent for the glaucoma drug Trusopt, which Tom Maren had helped to discover, ended. This was even greater than the royalty income per year of Gatorade, which had been discovered by a UF researcher, Robert Cade, in the 1960s.
- 205.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2002, p. 13
- 206.
Minutes of the meeting of the Board of Trustees, December 14, 2002, p. 1
- 207.
Op. Cit., pp. 2–3
- 208.
Op. Cit., p. 3
- 209.
By this time, the MDIBL staff seems to have forgotten that the main administrative building had been named Kingsley, with Smith a later addition on the rear. In fact, the new addition would be put onto Kingsley, not Smith.
- 210.
Minutes of the meeting of the Board of Trustees, December 14, 2002, pp. 3–4. The new gas fireplace inserts were required after a summer student attempted to light a fire in the unused and boarded up fireplace in the Oaks dormitory, despite warnings from fellow students. The ensuing, small but smoky, fire brought the local Fire Marshall to the Laboratory, prompting an inspection of all the fireplaces in MDIBL’s cottages and dormitories, which resulted in an order to refit all Laboratory fireplaces. Subsequent cottage dwellers missed the ambience of a wood fire but enjoyed the convenience of a remote-controlled gas fire on those early and late summer mornings and evenings.
- 211.
Minutes of the meeting of the Board of Trustees, December 14, 2002, p. 5
- 212.
Op. Cit., pp. 5–6
- 213.
Op. Cit., p. 6
- 214.
Op. Cit., p. 7
- 215.
Minutes of the Meeting of the Board of Trustees, April 12, 2003, pp. 1–2
- 216.
It is interesting to note that net balance that was transferred was some 50 % of the total budget of the MDIBL a decade before. Thus, the recent influx of major state and grant funds had put the Laboratory on a whole new fiscal plane.
- 217.
Minutes of the Meeting of the Board of Trustees, April 12, 2003, pp. 2–3
- 218.
Op. Cit., pp. 3–4
- 219.
Op. Cit., pp. 4–5
- 220.
Op. Cit., p. 5
- 221.
Op. Cit., pp. 5–6
- 222.
Op. Cit., pp. 6–7
- 223.
Op. Cit., pp. 7–8
- 224.
Op. Cit., p. 8
- 225.
Op. Cit., p. 9
- 226.
Minutes of the Annual Meeting of the Corporation, July 24, 2003, pp. 2–4 and 22
- 227.
Op. Cit., pp. 4–5
- 228.
Op. Cit., pp. 6–7
- 229.
Bernice Silk, widow of former Trustee Leonard Silk and a Julliard-trained pianist and teacher, had presented a concert in Maren that summer. See http://www.northjersey.com/obituaries/bernice-silk-83-1.310332.
- 230.
Minutes of the Annual Meeting of the Corporation, July 24, 2003, pp. 7–9
- 231.
Op. Cit., pp. 9–10
- 232.
Op. Cit., pp. 10–11
- 233.
Op. Cit., p. 12
- 234.
Op. Cit., p. 13
- 235.
Op. Cit., pp. 13–18
- 236.
Op. Cit., p. 19
- 237.
Op. Cit., pp. 19–20
- 238.
Op. Cit., pp. 20–21
- 239.
Op. Cit., p. 21
- 240.
Minutes of the Annual Meeting of the Board of Trustees, July 24, 2003, pp. 1–2
- 241.
Op. Cit., pp. 2–3
- 242.
Op. Cit., p. 3
- 243.
Note the term “funded scientists.” Forrest was well aware that the payback of construction costs and upkeep of the new building would have to be supported by direct and indirect income from new grants awarded to year-round Investigators.
- 244.
Minutes of the Annual Meeting of the Board of Trustees, July 24, 2003, pp. 4–5
- 245.
Op. Cit., pp. 5–6
- 246.
Op. Cit., p. 6
- 247.
This perspective was, of course, an outcome of the molecular biology that was now firmly part of the MDIBL’s research program. Benz went on to say, “It’s not just the equipment, and it’s not just the facilities. It’s the people who have to be here to provide the connections needed in genomics, proteomics, particularly in informatics, to draw on our electronic communications with our home institutions and with colleagues around the country or around the world.” In short, before the molecular age, individual research groups at the MDIBL were much more self-contained during the summer research period.
- 248.
Minutes of the Annual Meeting of the Board of Trustees, July 24, 2003, pp. 6–8
- 249.
Op. Cit., pp. 7–9
- 250.
Op. Cit., pp. 9–10
- 251.
Op. Cit., pp. 10–11
- 252.
Op. Cit., pp. 11–12
- 253.
Minutes of the meeting of the Board of Trustees, December 13, 2003, p. 1
- 254.
Averaged over the past two years, however, the MDIBL’s investment portfolio was still in negative territory.
- 255.
Minutes of the meeting of the Board of Trustees, December 13, 2003, pp. 1–2
- 256.
The MDIBL match for this NSF grant estimated to be $50,000 to $60,000, and Emily Maren had agreed to donate the necessary funds.
- 257.
Institutional Development Award
- 258.
Minutes of the meeting of the Board of Trustees, December 13, 2003, pp. 2–3
- 259.
Op. Cit., p. 3
- 260.
As mentioned previously (Fig. 6.5), the Wilde Cottage burned down two years later. The Byrnes Cottage remained less than optimal and was finally listed for public sale in 2013 and sold in the summer of 2014.
- 261.
Minutes of the meeting of the Board of Trustees, December 13, 2003, pp. 3–4. Unfortunately, no major renovations of the Investigator cottages ever took place, so they remain rather primitive—but have Internet access! The lack of modernized cottages has been a recruiting problem for the past 50 years of the MDIBL.
- 262.
Minutes of the meeting of the Board of Trustees, December 13, 2003, p. 4
- 263.
Op. Cit., pp. 4–5
- 264.
Op. Cit., p. 5
- 265.
$125,000 had been raised to date, with another $50,000 expected by the end of December.
- 266.
Minutes of the meeting of the Board of Trustees, December 13, 2003, p. 6
- 267.
Minutes of the meeting of the Board of Trustees, December 13, 2003, pp. 6–7
- 268.
Op. Cit., pp. 7
- 269.
Op. Cit., pp. 7–8
- 270.
Minutes of the meeting of the Board of Trustees, April 3, 2004, p. 1
- 271.
Op. Cit., pp. 1–2
- 272.
Op. Cit., p. 2
- 273.
Op. Cit., pp. 2–3
- 274.
Op. Cit., pp. 3–4
- 275.
A noted hematologist, Jessica Lewis was the daughter of Warren and Margaret Lewis, who had worked at both the Harpswell Laboratory and the MDIBL in the first half of the twentieth century. She had recently donated funds to construct the Myers Aquarium at the Laboratory. Roger Chagnon was the husband of Bodil Schmidt-Nielsen and had been involved in fund-raising at the Laboratory in the early 1980s and in the formation of the “Friends of the Laboratory,” an early attempt to interest local nonscientists in the MDIBL.
- 276.
Minutes of the Annual Meeting of the Corporation, July 22, 2004, p. 2
- 277.
Op. Cit., pp. 2–3 and 18
- 278.
Op. Cit., pp. 3–4
- 279.
- 280.
Minutes of the Annual Meeting of the Corporation, July 22, 2004, pp. 7–8
- 281.
Op. Cit., pp. 7–9
- 282.
Boyer and Carolyn Mattingly were planning to submit a proposal to the NIEHS for continued funding of the CTD.
- 283.
Minutes of the Annual Meeting of the Corporation, July 22, 2004, pp. 9–10
- 284.
Op. Cit., pp. 11–13
- 285.
Op. Cit., pp. 13–14
- 286.
The grant has already been introduced in this narrative, so only some new facts will be presented here.
- 287.
Minutes of the Annual Meeting of the Corporation, July 22, 2004, pp. 14–16
- 288.
Op. Cit., p. 17
- 289.
Ibid.
- 290.
Minutes of the Annual Meeting of the Board of Trustees, July 22, 2004, pp. 1–2
- 291.
Op. Cit., pp. 2–4. To this end, the LRPC, in particular Ed Benz and Ray Frizzell (with the assistance of John Forrest and Patricia Hand), convened a series of “town meetings” with current MDIBL Investigators at the end of that summer to “discern the major trends that should influence recommendations concerning scientific content of the next long-range plan.” Participants “were asked to make projections about the major trends in their broader areas of science, opportunities for federal funding, and ways that their area might interact with other areas to give the lab the right balance of breadth and focus. The areas chosen were: membrane transport, neuroscience, toxicology, and development biology.” Only the minutes of the membrane biology group are available in MDIBL Archives. That group concluded that there was “need for the lab to focus on, and provide support for, a more ‘cell biological’ approach to membrane biology. Whereas many members of the lab have successfully focused on understanding the property and behavior of one or a small set of transport molecules, it is now clear that the physiologic impact of these molecules involves participation in multi-molecular complexes, interactions with sub-cellular organelles, and regulation and function based on both pathology and molecular interactions. Thus, understanding the physiologic importance of these molecules will require new capability and tracking multi-molecular complexes, imaging cells and molecules, and manipulating high order molecular complexes simultaneously in tissue culture or whole animals.”
- 292.
Minutes of the Annual Meeting of the Board of Trustees, July 22, 2004, p. 3
- 293.
Op. Cit., pp. 4–6. Forrest reminded the Board that the IC rate would drop to 36 % from the current 62 % unless the Laboratory received the grant or borrowed the money.
- 294.
Minutes of the Annual Meeting of the Board of Trustees, July 22, 2004, p. 6
- 295.
Op, Cit., pp. 6–7
- 296.
Op. Cit., p. 8
- 297.
This would prove to be a very strategic addition to the Board. The Morris family would make several substantial gifts to the MDIBL in the next decade, and Wistar Morris continues to be the only non-scientist member of the Board who routinely attends most Laboratory seminars during July each summer.
- 298.
Minutes of the meeting of the Board of Trustees, December 11, 2004, pp. 1–2. Read had been CEO of Bar Harbor Banking and Trust and had been recruited onto the MDIBL’s Finance Committee, as a non-Board member.
- 299.
The new proposal “addressed critiques [of the first proposal] that MDIBL is not big enough for a year-round program, and described in more detail scientific resources at the Lab.”
- 300.
Minutes of the meeting of the Board of Trustees, December 11, 2004, p. 3
- 301.
Ibid.
- 302.
Op. Cit., pp. 4
- 303.
Ibid.
- 304.
Planchart will be introduced in the next chapter.
- 305.
Op. Cit., pp. 5–6
- 306.
In fact, fishes do not have a significantly simpler body organization, biochemistry, or physiology, but they do provide a window to the evolution of structure and function, and regulations for their use for various protocols are not as restrictive as they are for mammals.
- 307.
Op. Cit., p. 6
- 308.
Op. Cit., pp. 6–7
- 309.
Op. Cit., pp. 7–8
- 310.
Op. Cit., pp. 8–9
- 311.
Op. Cit., p. 9
- 312.
Op. Cit., p. 10. Subsequently, the land donation was approved by the Board.
- 313.
Enacted in 2002, Sarbanes-Oxley (known as “Public Company Accounting Reform and Investor Protection Act” in the Senate and “Corporate and Auditing Accountability and Responsibility Act” in the House) “set new or enhanced standards for all U.S. public company boards, management and public accounting firms.” At this point, Sarbanes-Oxley’s potential impact on nonprofit corporations was unclear. (See http://en.wikipedia.org/wiki/Sarbanes–Oxley_Act and http://www.soxlaw.com.)
- 314.
Minutes of the Meeting of the Board of Trustees, April 2, 2005, p. 2
- 315.
Op. Cit., pp. 2–3
- 316.
Op. Cit., p. 4
- 317.
The lower the score, the better in NIH proposals, and a score above 150–160 was often the cutoff for funding in those years.
- 318.
This was during the height of the war in Iraq.
- 319.
Minutes of the Meeting of the Board of Trustees, April 2, 2005, pp. 5–6
- 320.
Op. Cit. p. 7
- 321.
Coffman will be introduced in the next chapter.
- 322.
Minutes of the Meeting of the Board of Trustees, April 2, 2005, p. 7
- 323.
The genome of the zebra fish (Danio rerio) and the fugu (Takifugu rubripes; puffer fish) had been sequenced by this point.
- 324.
Minutes of the Meeting of the Board of Trustees, April 2, 2005, pp. 8–9
- 325.
Op. Cit., p. 9. This confluence of funding problems and changed family dynamics has been noted in a previous chapter, but it is worth repeating, because the trend has continued and has had a significant impact on the summer (seasonal) research at the MDIBL for the past two decades. Starting at the end of the twentieth century, the days were simply gone when a new Investigator could bring his/her young children and trailing spouse to the MDIBL for most of the summer.
- 326.
Minutes of the Meeting of the Board of Trustees, April 2, 2005, p. 9
- 327.
Op. Cit., pp. 9–10
- 328.
Op. Cit., pp. 10–11
- 329.
The results of these efforts can be seen at http://skatebase.org.
- 330.
Minutes of the Meeting of the Board of Trustees, April 2, 2005, pp. 11–14
- 331.
Op. Cit., pp. 14–15
- 332.
Op. Cit., p. 16
- 333.
Minutes of the Annual Meeting of the Corporation, July 28, 2005, pp. 2–3 and 16
- 334.
Op. Cit. p. 3. Despite yearly withdrawals of approximately $80,000 for fellowships, the SCRF had nearly $1.7 M in assets as of the summer of 2015, when it was still providing the majority of funds for new Investigator fellowships at the MDIBL.
- 335.
Minutes of the Annual Meeting of the Corporation, July 28, 2005, pp. 3–4
- 336.
Op. Cit., pp. 5–6
- 337.
See Chap. 2.
- 338.
Minutes of the Annual Meeting of the Corporation, July 28, 2005, pp. 7–9
- 339.
Op. Cit., p. 9
- 340.
Op. Cit., pp. 9–10
- 341.
Since most of her comments are not directly relevant to this narrative or repeated what has already been noted about the IDeA Program, the address will not be discussed further. It can be read at Minutes of the Annual Meeting of the Corporation, July 28, 2005, pp. 10–13.
- 342.
Minutes of the Annual Meeting of the Corporation, July 28, 2005, pp. 13–14
- 343.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2005, pp. 1–3
- 344.
Op. Cit., pp. 4–6
- 345.
Hays was referring to the general consensus that an investigator who was supporting his/her research group on federal funds needed at least two grants to provide the direct and indirect costs necessary for that group to have year-round research space at the MDIBL.
- 346.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2005, pp. 6–8
- 347.
Op. Cit., p. 8
- 348.
As mentioned previously, estimates were that Maine’s previous investment of $42 M in biomedical research had resulted in $279 M in outside funding.
- 349.
Minutes of the Annual Meeting of the Board of Trustees, July 25, 2005, pp. 8–10
- 350.
Op. Cit., p. 10
- 351.
Op. Cit., pp. 10–11
- 352.
Op. Cit., pp. 11–12
- 353.
Op. Cit., pp. 12–13
- 354.
Op. Cit., p. 13
- 355.
Op. Cit., p. 14
- 356.
Op. Cit., pp. 15–16
- 357.
Minutes of the Meeting of the Board of Trustees, December 3, 2005, pp. 1–2
- 358.
Leadership in Energy and Environmental Design (LEED) is “a third-party certification program…for design, operation, and construction of high performance green buildings” (http://www.leed.net).
- 359.
Minutes of the Meeting of the Board of Trustees, December 3, 2005, pp. 2–3
- 360.
Op. Cit., pp. 4–5
- 361.
Op. Cit., pp. 5–6
- 362.
Minutes of the Meeting of the Board of Trustees, December 3, 2005, pp. 6–7
- 363.
Hartline is the son of Haldan Hartline, who shared the Nobel Prize in Physiology and Medicine with Ragnar Granit and George Wald, for their studies of the electrophysiology of vision. Interestingly, the senior Hartline had received his M.D. from Johns Hopkins in 1927, where he studied with E. K. Marshall, who had just started to work at the MDIBL. (See http://www.nobelprize.org/nobel_prizes/medicine/laureates/1967/hartline-bio.html.)
- 364.
Copepods are small crustaceans that dominate in the oceans’ planktonic biomass and are, therefore, vital to marine food webs. The local species is Calanus finmarchicus. (See http://www.gma.org/herring/biology/ecology/copepods.asp.)
- 365.
Minutes of the Meeting of the Board of Trustees, December 3, 2005, p. 7
- 366.
Op. Cit., pp. 7–8
- 367.
Minutes of the Meeting of the Board of Trustees, December 3, 2005, pp. 8–9
- 368.
Op. Cit., pp. 9–10. Obviously, this exchange had been yet another chapter in the historical tension between MDIBL’s Director and Board of Trustees, but it had ended amicably. The tension still exists and is probably just a character of this type of administrative structure in a nonprofit organization.
- 369.
Minutes of the Meeting of the Board of Trustees, December 3, 2005, pp. 10–12
- 370.
Op. Cit., pp. 13–14
- 371.
Op. Cit., pp. 14–15
- 372.
Op. Cit., pp. 15–16
- 373.
Op. Cit., pp. 16–17
- 374.
Op. Cit., p. 17
- 375.
Op. Cit., pp. 17–18
- 376.
Op. Cit., pp. 18–19
- 377.
Minutes of the Meeting of the Board of Trustees, April 1, 2006, p. 2. The author, of course, appreciates this decision.
- 378.
The operating budget of the MDIBL was now approximately $7.5 M per year.
- 379.
Minutes of the Meeting of the Board of Trustees, April 1, 2006, pp. 2–3
- 380.
Op. Cit., pp. 3–4
- 381.
Op. Cit., p. 4
- 382.
Op. Cit., pp. 4–6
- 383.
Op. Cit.. p. 6
- 384.
This is the first indication that the staff had started to work on getting a special federal appropriation (often termed an “earmark”) for the Laboratory. As we shall see, within four years these efforts were successful, with significant impacts on the future of the MDIBL.
- 385.
Minutes of the Meeting of the Board of Trustees, April 1, 2006, pp. 6–7
- 386.
Op. Cit., p. 7
- 387.
Op. Cit., p. 8
- 388.
Op. Cit., pp. 8–10. Hand’s Report was, of course, much more detailed than what is warranted for this story.
- 389.
Minutes of the Meeting of the Board of Trustees, April 1, 2006, p. 10
- 390.
Since 2002, under the leadership of a new Director (Elias Zerhouni, M.D.), the NIH had shifted its focus of interest (and funding) from “bench to bedside” (translational research—the application of basic scientific findings to disease prevention and cure) to “bedside to bench” (the focus on the study of a particular disease). See http://www.nih.gov/news/health/sep2008/od-24.htm.
- 391.
Minutes of the Meeting of the Board of Trustees, April 1, 2006, p. 11
- 392.
Op. Cit., pp. 11–12
- 393.
Op. Cit., p. 12
- 394.
Op. Cit., pp. 12–13
- 395.
Op. Cit., pp. 13–15
- 396.
At this point, the operating revenue and expenses were approximately $7.5 M per year.
- 397.
Minutes of the Annual Meeting of the Corporation, July 27, 2006, pp. 1–4, 12–13
- 398.
Disney (Fig. 13.11) had received her Ph.D. in Zoology from Washington State University, taught at MDI High School and College of the Atlantic, and worked with the MDI Water Quality Coalition before joining the MDIBL staff as an Outreach Educator in 2009.
- 399.
The Squalus, the Laboratory’s original collecting boat, had been purchased in 1958 and scrapped in 1986.
- 400.
Minutes of the Annual Meeting of the Corporation, July 27, 2006, pp. 5–6
- 401.
Op. Cit., pp. 6–7
- 402.
- 403.
Minutes of the Annual Meeting of the Corporation, July 27, 2006, p. 7
- 404.
As of 2015, the MDIBL was ranked with three stars: http://www.charitynavigator.org/index.cfm?bay=search.summary&orgid=5954#.U-kMiVZmtj4.
- 405.
Minutes of the Annual Meeting of the Corporation, July 27, 2006, pp. 7–8
- 406.
Op. Cit., p. 8
- 407.
Op. Cit., pp. 6 and 8
- 408.
Op. Cit., p. 8
- 409.
Op. Cit., pp. 8–10
- 410.
Minutes of the Annual Meeting of the Board of Trustees, July 27, 2006, pp. 1–2
- 411.
Op. Cit., pp. 2–3
- 412.
Op. Cit., pp. 3–4
- 413.
Op. Cit., p. 4
- 414.
Op. Cit., pp. 5–6
- 415.
Benz was using “leverage’ in the sense of collaborating with extramural institutions, departments, and colleagues to increase the research and administrative scope of the MDIBL. A case in point was the subsequent collaboration with Dartmouth Medical School to allow access to online journals, something which the MDIBL could not provide.
- 416.
Minutes of the Annual Meeting of the Board of Trustees, July 27, 2006, pp. 6–7
- 417.
Op. Cit., p. 7
- 418.
Op. Cit., p. 8
- 419.
Op. Cit., p. 9
- 420.
Op. Cit., pp. 9–10
- 421.
Dan Smith had been a Research Fellow in Jim Boyer’s Laboratory at the MDIBL in the early 1980s.
- 422.
As noted earlier, an “earmark” is an addendum to a congressional bill allocating money for a specific need in a congressman’s home district. As one might expect, the emerging use of (non-peer-reviewed) earmarks for funding institutional construction and research was controversial, but, nevertheless, practiced by many US research institutions.
- 423.
Minutes of the Annual Meeting of the Board of Trustees, July 27, 2006, pp. 10–11
- 424.
- 425.
Minutes of the Meeting of the Board of Trustees, December 2, 2006, p. 1. Kathryn Davis (1907–2013), a noted philanthropist and peace advocate, had summered on MDI for many years. (See http://en.wikipedia.org/wiki/Kathryn_Wasserman_Davis.)
- 426.
Minutes of the Meeting of the Board of Trustees, December 2, 2006, pp. 2–3
- 427.
Op. Cit., p. 3
- 428.
Op. Cit., pp. 3–4
- 429.
Op. Cit., p. 4
- 430.
Minutes of the Meeting of the Board of Trustees, December 2, 2006, p. 4
- 431.
Op. Cit., p. 5
- 432.
Op. Cit., p. 6
- 433.
Ibid.
- 434.
Minutes of the Meeting of the Board of Trustees, April 14, 2007, p. 1. The “high-profile” speaker had been former Senator George Mitchell.
- 435.
Minutes of the Meeting of the Board of Trustees, April 14, 2007, p. 1
- 436.
Op. Cit., p. 2
- 437.
Op. Cit., pp. 2–3
- 438.
Op. Cit., p. 3
- 439.
Unfortunately, the event never took place.
- 440.
Minutes of the Meeting of the Board of Trustees, April 14, 2007, pp. 3–4
- 441.
Op. Cit., p. 4
- 442.
Ibid.
- 443.
Op. Cit., p. 5
- 444.
Ibid.
- 445.
Minutes of the Annual Meeting of the Corporation, July 26, 2007, p. 1
- 446.
Op. Cit., pp. 2, 10–11
- 447.
Op. Cit., p. 2
- 448.
Op. Cit., pp. 8–9
- 449.
The current protocol used by the Nominating Committee was to request a curriculum vitae, letter of intent, and letters of recommendation before presenting the candidate to the Board of Trustees and Corporation. The MDIBL By-Laws had not been changed since Trustees, who had always been Investigators at the MDIBL and therefore known to all, were merely nominated from the floor at the Annual Corporation Meeting. The new protocol was necessary since many Trustees now were not members of the MDIBL community.
- 450.
Op. Cit., p. 4
- 451.
Op. Cit., pp. 4–5
- 452.
Op. Cit., p. 5
- 453.
Fellner was a relatively new Investigator at the MDIBL; her research will be introduced in the next chapter.
- 454.
Minutes of the Annual Meeting of the Corporation, July 26, 2007, p. 5
- 455.
Op. Cit., p. 6
- 456.
Ibid.
- 457.
Op. Cit., pp. 6–7
- 458.
Op. Cit., p. 7
- 459.
Minutes of the Annual Meeting of the Board of Trustees, July 26, 2007, pp. 1–2
- 460.
Smithies, a geneticist at the University of North Carolina, Chapel Hill, was awarded the Nobel Prize in Physiology and Medicine later that year, for his work “introducing specific gene modifications in mice by the use of embryonic stem cells.” (See http://www.nobelprize.org/nobel_prizes/medicine/laureates/2007/smithies-facts.html.)
- 461.
Op. Cit., p. 2
- 462.
Op. Cit., p. 3
- 463.
Minutes of the Annual Meeting of the Board of Trustees, July 26, 2007, p. 3
- 464.
The Laboratory still held 20 shares of MariCal stock and received an Annual Report from the company each year. In 2006, they had reported $2 M in revenue and a loss of $1.5 M. Unfortunately, by 2015, MariCal appeared to be out of business (Google search).
- 465.
Minutes of the Annual Meeting of the Board of Trustees, July 26, 2007, p. 4
- 466.
Minutes of the Meeting of the Board of Trustees, December 1, 2007, p. 1
- 467.
Op. Cit., pp. 2–3
- 468.
The STEER proposal, which had received a score of 125 (and would be funded in January 2008), would provide $40,000 for the support of high school students; the animal facilities proposal, which had received a score of 130, would renovate the animal holding facilities in Marshall laboratory and the Fish Shed (across from Marshall).
- 469.
Minutes of the Meeting of the Board of Trustees, December 1, 2007, pp. 3–4. The
Wilde Cottage had not been replaced as of 2015.
- 470.
Op. Cit., p. 4
- 471.
Minutes of the Meeting of the Board of Trustees, December 1, 2007, p. 4
- 472.
Ibid.
- 473.
Current funding rates for Investigator-generated proposals to many sections of the NIH and NSF are generally considered to be approximately 10 %, although success rates in specialized programs are usually higher.
- 474.
Minutes of the Meeting of the Board of Trustees, December 1, 2007, p. 5
- 475.
Ibid.
- 476.
Op. Cit., pp. 5–6
- 477.
Op. Cit., p. 6
- 478.
Op. Cit., pp. 6–7
- 479.
Op. Cit., p. 7. Mrs. Davis passed away in 2013, at the age of 106.
- 480.
Minutes of the Meeting of the Board of Trustees, December 1, 2007, p. 7
- 481.
Ibid.
- 482.
Minutes of the Meeting of the Board of Trustees, April 5, 2008, pp. 1–2
- 483.
Op. Cit., p. 2
- 484.
Op. Cit., pp. 2–3
- 485.
Op. Cit., p. 3. Wistar Morris commented that coming in under budget “was quite an achievement, given rising prices for construction materials.”
- 486.
Minutes of the Meeting of the Board of Trustees, April 5, 2008, p. 3
- 487.
Op. Cit., p. 4
- 488.
Op. Cit., pp. 4–5
- 489.
Op. Cit., p. 5
- 490.
Op. Cit., p. 6
- 491.
Op. Cit., pp. 6–7
- 492.
Op. Cit., pp. 7–8
- 493.
Op. Cit., pp. 8–9
- 494.
Op. Cit., p. 9
- 495.
Op. Cit., pp. 9–10
- 496.
As mentioned earlier, the NIH was focusing more on translational science than basic science at this point. The MDIBL, of course, did not have a clinical component, but potential collaboration with Dartmouth, which did, could help future MDIBL grant proposals to the NIH.
- 497.
Minutes of the Meeting of the Board of Trustees, April 5, 2008, p. 10
- 498.
Op. Cit., pp. 10–11
- 499.
Op. Cit., pp. 11–12
- 500.
Minutes of the Annual Meeting of the Corporation, July 24, 2008, p. 1
- 501.
Op. Cit., pp. 2–3
- 502.
Op. Cit., p. 3
- 503.
Op. Cit., p. 4
- 504.
Op. Cit., pp. 4–5
- 505.
Op. Cit., p. 5
- 506.
Ibid.
- 507.
Op. Cit., pp. 5–6
- 508.
Op. Cit., p. 6
- 509.
Ibid.
- 510.
Op. Cit. pp. 6–7
- 511.
- 512.
Minutes of the Annual Meeting of the Corporation, July 24, 2008, p. 7
- 513.
Op. Cit., p. 8
- 514.
Minutes of the Annual Meeting of the Trustees, July 24, 2008, pp. 1–2
- 515.
Op. Cit., pp. 2–3
- 516.
Op. Cit., p. 3
- 517.
The economic downturn, now termed the “Great Recession” of 2007–2008, was underway. See http://en.wikipedia.org/wiki/Great_Recession and http://news.bbc.co.uk/2/hi/business/8242825.stm.
Ironically, as we shall see later in this chapter, one outcome of the Great Recession, the American Recovery and Reinvestment Act of 2009, actually produced an unexpected, substantial windfall for the MDIBL’s infrastructure.
- 518.
Always au courant, the MDIBL had now entered the Facebook and Twitter generation. There was no turning back.
- 519.
Minutes of the Annual Meeting of the Trustees, July 24, 2008, p. 4
- 520.
- 521.
Minutes of the Meeting of the Board of Trustees, December 4, 2008, p. 1
- 522.
Op. Cit. p. 2. Uncharacteristically, but understandable because of the usual confidentiality of academic searches, there had been no previous mention of the Board’s deliberations or selection. There had been extensive interviews of Dr. Strange during the previous summer, and the vote of the Trustees was presumably by mail. Dr. Strange, who had worked at the MDIBL in the summer of 1994, will be more formally introduced when he gives his first report to the Board at the spring 2009 meeting.
- 523.
Minutes of the Meeting of the Board of Trustees, December 4, 2008, p. 2
- 524.
Op. Cit., p. 3
- 525.
Ibid.
- 526.
Op. Cit., p. 4
- 527.
Ibid.
- 528.
Op. Cit., pp. 4–5
- 529.
Op. Cit., p. 5: Christie and Dahn will be introduced in the next chapter.
- 530.
Op. Cit., pp. 5–6
- 531.
Op. Cit., p. 6
- 532.
Op. Cit., pp. 6–7. Clearly, the success rate of the New Investigator Program was not as high as expected. Explanations abounded, but it was clear that societal changes (working spouses) and decreased federal grant funding levels played significant roles.
- 533.
Op. Cit., p. 7
- 534.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, pp. 3–4. There are no pages 1 and 2 in the published Corporation Minutes for April 2009 to January 2010.
- 535.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, pp. 4–5
- 536.
Op. Cit., p. 5
- 537.
Op. Cit., p. 6
- 538.
Op. Cit., pp. 6–7
- 539.
Op. Cit., pp. 7–8
- 540.
Op. Cit., p. 8
- 541.
Op. Cit., pp. 8–9
- 542.
This attempt to secure a federal appropriation, or “earmark,” had begun in 2006. It had gained momentum when Michaud had visited Randy Dahn’s new laboratory at the MDIBL in the winter of 2009 and become extremely impressed with the potential (for wounded veterans) of the regeneration studies that Dahn had begun on skates while a postdoctoral fellow at the University of Chicago and planned to continue at the MDIBL.
- 543.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, p. 9
- 544.
Op. Cit, pp. 9–10
- 545.
Op. Cit., p. 10
- 546.
Strange (Fig. 13.14) had received his Ph.D. from the University of British Columbia in 1983, been a postdoctoral fellow in the Laboratory of Kidney and Electrolyte Metabolism at the NIH, and held faculty positions at Wright State University, Harvard Medical School, and Vanderbilt University School of Medicine before becoming the first year-round Director of the MDIBL in 2009.
- 547.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, pp. 10–11
- 548.
Op. Cit., pp. 11–12
- 549.
Op. Cit. p. 12; for more on the Aspirnaut program, see http://www.aspirnaut.org.
- 550.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, p. 12
- 551.
Ibid.
- 552.
Although plans has already been made for the announcement of the renewal at the statehouse in Augusta, with Governor Baldacci and the Associate Director of the NCRR attending
- 553.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, p. 13
- 554.
Ibid.
- 555.
Op. Cit., pp. 13–14. Unfortunately, there are some 150 nonprofit organizations on MDI, all asking for support, and many holding Annual Galas. The MDIBL started holding an Annual Gala two years later.
- 556.
Minutes of the Meeting of the Board of Trustees, April 4, 2009, p. 14
- 557.
Ibid.
- 558.
Op. Cit., pp. 14–15
- 559.
Op. Cit., p. 15
- 560.
Op. Cit., pp. 15–16
- 561.
Minutes of the Annual Meeting of the Corporation, July 23, 2009, p. 2
- 562.
Op. Cit., pp. 2–3
- 563.
Op. Cit., p. 3
- 564.
After spending most of his summer’s growing up at the MDIBL, the younger Dr. Forrest was then a Fellow in Cardiology at Yale University School of Medicine, where he is currently an Assistant Professor in Cardiovascular Medicine.
- 565.
Minutes of the Annual Meeting of the Corporation, July 23, 2009, p. 4
- 566.
Op. Cit., pp. 4–5
- 567.
Op. Cit., pp. 5–6
- 568.
Op. Cit., p. 6
- 569.
Op. Cit., pp. 6–7
- 570.
Op. Cit., p. 7
- 571.
Op. Cit., p. 8
- 572.
There were those in the audience, of course, who felt that the MDIBL had begun to be a “world-class institution” in the 1920s.
- 573.
Minutes of the Annual Meeting of the Corporation, July 23, 2009, p. 8
- 574.
As mentioned earlier, Strange had been elected by the Trustees in November, 2008. Academic transitions, however, take time, so he would not arrive to work full time at the MDIBL until early 2010. Forrest had agreed to help with the transition during the fall of 2009.
- 575.
Minutes of the Annual Meeting of the Corporation, July 23, 2009, pp. 8–9
- 576.
The Howard Hughes Medical Institute had just released a report “encouraging more laboratory training for physicians.”
- 577.
Minutes of the Annual Meeting of the Corporation, July 23, 2009, p. 9
- 578.
Op. Cit., pp. 9–10
- 579.
Op. Cit., p. 10
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Evans, D.H. (2015). The MDIBL in the Early Twenty-First Century: A New Beginning. In: Marine Physiology Down East: The Story of the Mt. Desert Island Biological Laboratory. Perspectives in Physiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2960-3_13
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