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Gene-Environment Interplay in Parenting Young Children

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Part of the book series: Advances in Behavior Genetics ((AIBG,volume 3))

Abstract

Early parenting is rooted in a complex social system where parental characteristics, contextual factors and child characteristics interact over time. A comprehensive study of early parenting should thus consider a variety of factors, including those associated with the infant (so called “child effects”). Understanding such a complex developmental system is a daunting task, and behaviour-genetic studies, because they are designed to test hypotheses regarding gene-environment processes, are very useful in that endeavour. In the past decade, studies using a variety of genetically informative designs, including twin, adoption, step-family and linkage (i.e., molecular) designs, have shed new light on early parenting and the nature of its association with child socio-emotional development. In this chapter, we review this emerging evidence. Specifically, the chapter examines and discusses environmental and genetic influences, as well as their interplay, on infant attachment and various parenting behaviours. Data pointing to “child effects” on parenting behaviours (i.e. gene-environment correlations) are reviewed, as well as evidence of parental influence on child outcomes and its possible mediation through child heritable characteristics. We discuss the significance of these findings for our understanding of the developmental role of early parenting. We conclude with a discussion of methodological concerns, gaps, and future directions regarding behaviour-genetics research in early parenting.

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References

  • Ainsworth, M. D. (1985). Attachments across the life span. Bulletin of the New York Academy of Medicine, 61, 792–812.

    PubMed Central  PubMed  Google Scholar 

  • Ainsworth, M. D., Blehar, M. C., Waters, E., & Wall, S. (1978). Patterns of attachment: A psychological study of the strange situation. Hillsdale, IN: Erlbaum.

    Google Scholar 

  • Alemany, S., Rijsdijk, F. V., Haworth, C. M., Fañanás, L., & Plomin, R. (2013). Genetic origin of the relationship between parental negativity and behavior problems from early childhood to adolescence: A longitudinal genetically sensitive study. Development and Psychopathology, 25, 487–500.

    PubMed  Google Scholar 

  • Asbury, K., Dunn, J. F., Pike, A., & Plomin, R. (2003). Nonshared environmental influences on individual differences in early behavioral development: A monozygotic twin differences study. Child Development, 74, 933–943.

    PubMed  Google Scholar 

  • Asbury, K., Wachs, F. P., & Plomin, R. (2005). Environmental moderators of genetic influence on verbal and nonverbal abilities in early childhood. Intelligence, 33(6), 643–661.

    Google Scholar 

  • Asbury, K. J., Wachs, F. P., & Plomin, R. (2006). Birthweight-discordance and differences in early parenting relate to monozygotic twin differences in behavior problems and academic achievement at age 7. Developmental Science, 9, F22–F31.

    PubMed  Google Scholar 

  • Atkinson, L., Chisholm, V. C., Scott, B. G., Goldberg, S., Vaughn, B. E., Blackwell, J., et al. (1999). Maternal sensitivity, child functional level, and attachment in Down syndrome. Monographs of the Society for Research in Child Development, 64(3), 45–66.

    PubMed  Google Scholar 

  • Avinun, R., Ebstein, R. P., & Knafo, A. (2012). Human maternal behaviour is associated with arginine vasopressin receptor 1A gene. Biology Letters, 8, 894–896.

    PubMed Central  PubMed  Google Scholar 

  • Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2004). No association of the dopamine D4 receptor (DRD4) and -521 C/T promoter polymorphisms with infant attachment disorganization. Attachment & Human Development, 6(3), 211–222.

    Google Scholar 

  • Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2006). Gene-environment interaction of the dopamine D4 receptor (DRD4) and observed maternal insensitivity predicting externalizing behavior in preschoolers. Developmental Psychobiology, 48(5), 406–409.

    PubMed  Google Scholar 

  • Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2008). Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting. Social Cognitive and Affective Neuroscience, 3(2), 128–134.

    PubMed Central  PubMed  Google Scholar 

  • Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Bokhorst, C. L., & Schuengel, C. (2004). The importance of shared environment in infant–father attachment. A behavioral genetic study of the Attachment Q-Sort. Journal of Family Psychology, 18, 545–549.

    Google Scholar 

  • Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Mesman, J., Alink, L. R., & Juffer, F. (2008a). Effects of an attachment-based intervention on daily cortisol moderated by dopamine receptor D4: A randomized control trial on 1- to 3-year-olds screened for externalizing behavior. Development and Psychopathology, 20(3), 805–820.

    PubMed  Google Scholar 

  • Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Pijlman, F. T. A., Mesman, J., & Juffer, F. (2008b). Experimental evidence for differential susceptibility: Dopamine D4 receptor polymorphism (DRD4 VNTR) moderates intervention effects on toddlers’ externalizing behavior in a randomized controlled trial. Developmental Psychology, 44(1), 293–300.

    PubMed  Google Scholar 

  • Barry, R. A., Kochanska, G., & Philibert, R. A. (2008). G x E interaction in the organization of attachment: mothers’ responsiveness as a moderator of children’s genotypes. Journal of Child Psychology and Psychiatry and Allied Disciplines, 49(12), 1313–1320.

    Google Scholar 

  • Becker, K. D., Ginsburg, G. S., Domingues, J., & Tein, J.-Y. (2010). Maternal control behavior and locus of control: Examining mechanisms in the relation between maternal anxiety disorders and anxiety symptomatology in children. Journal of Abnormal Child Psychology, 38, 533–543.

    PubMed Central  PubMed  Google Scholar 

  • Belsky, J. (1984). The determinants of parenting: A process model. Child Development, 55, 83–96.

    PubMed  Google Scholar 

  • Belsky, J., & Jaffee, S. R. (2006). The multiple determinants of parenting. In D. Cicchetti & D. J. Donald (Eds.), Developmental Psychopathology, Vol. 3: Risk, Disorder, and Adaptation (pp. 38–85). Hoboken, NJ: Wiley.

    Google Scholar 

  • Belsky, J., & Pluess, M. (2009). Beyond diathesis stress: Differential susceptibility to environmental influences. Psychological Bulletin, 135(6), 885–908.

    PubMed  Google Scholar 

  • Benjamin, J., Li, L., Patterson, C., Greenberg, B. D., Murphy, D. L., & Hamer, D. H. (1996). Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking. Nature Genetics, 2(1), 81–84.

    Google Scholar 

  • Boeldt, D. L., Rhee, S. H., DiLalla, L. F., Mullineaux, P. Y., Schulz, H. R., et al. (2012). The association between positive parenting and externalizing behavior. Infant and Child Development, 21(1), 85–106.

    PubMed Central  PubMed  Google Scholar 

  • Boivin, M., Pérusse, D., Dionne, G., Saysset, V., Zoccolillo, M., Tarabulsy, G., et al. (2005). Parent’s perceptions and self-assessed behaviors toward their 5-month-old infants in a large twin and singleton sample. Journal of Child Psychology and Psychiatry and Allied Disciplines, 46, 612–630.

    Google Scholar 

  • Bokhorst, C. L., Bakermans-Kranenburg, M. J., Fearon, R. M., van IJzendoorn, M. H., Fonagy, P., & Schuengel, C. (2003). The importance of shared environment in mother–infant attachment security: A behavioral genetic study. Child Development, 74, 1769–1782.

    PubMed  Google Scholar 

  • Bornstein, M. C. (2002). Handbook of parenting (Vol. 1–4). Mahwah, NJ: Erlbaum.

    Google Scholar 

  • Bowlby, J. (1982). Attachment and loss (vol. 1): Attachment (2nd ed.). London, UK: Hogarth Press.

    Google Scholar 

  • Bradley, R. H., & Corwyn, R. F. (2007). Externalizing problems in fifth grade: Relations with productive activity, maternal sensitivity, and harsh parenting from infancy through middle childhood. Developmental Psychology, 43(6), 1390–1401.

    PubMed  Google Scholar 

  • Braungart-Rieker, J. M., Fulker, D. W., & Plomin, R. (1992). Genetic mediation of the home environment during infancy: A sibling adoption study of the HOME. Developmental Psychology, 28(6), 1048–1055.

    Google Scholar 

  • Braungart-Rieker, J. M., Rende, R. D., Plomin, R., & DeFries, J. C. (1995). Genetic mediation of longitudinal associations between family environment and childhood behavior problems. Development and Psychopathology, 7, 233–245.

    Google Scholar 

  • Bretherton, I., & Waters, E. (Eds.). (1985). Growing points of attachment theory and research. Monographs of the Society for Research in Child Development. Serial No. 209.

    Google Scholar 

  • Brown, S. M., & Hariri, A. R. (2006). Neuroimaging studies of serotonin gene polymorphisms: Exploring the interplay of genes, brain, and behavior. Cognitive, Affective & Behavioral Neuroscience, 6(1), 44–52.

    Google Scholar 

  • Brunner, H. G., & Nelen, M. (1993). Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science, 262(5133), 578–781.

    PubMed  Google Scholar 

  • Campbell, S. B., Brownell, C. A., Hugerford, A., Spieker, S. I., Mohan, R., & Blessing, J. S. (2004). The course of maternal depressive symptoms and maternal sensitivity as predictors of attachment security at 36 months. Development and Psychopathology, 16, 231–252.

    Google Scholar 

  • Campbell, S. B., Matestic, P., von Stauffenberg, C., Mohan, R., & Kirchner, T. (2007). Trajectories of maternal depressive symptoms, maternal sensitivity, and children’s functioning at school entry. Developmental Psychology, 43(5), 1202–1215.

    PubMed  Google Scholar 

  • Canli, T., & Lesch, K.-P. (2007). Long story short: The serotonin transporter in emotion regulation and social cognition. Nature Neuroscience, 10, 1103–1109.

    PubMed  Google Scholar 

  • Carpenter, L. L., Shattuck, T. T., Tyrka, A. R., Geracioti, T. D., & Price, L. H. (2011). Effect of childhood physical abuse on cortisol stress response. Psychopharmacology (Berl), 214, 367–375.

    Google Scholar 

  • Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851–854.

    PubMed  Google Scholar 

  • Caspi, A., Moffit, T. E., Morgan, J., Rutter, M., Taylor, A., Arseneault, L., et al. (2004). Maternal expressed emotion predicts children’s antisocial behavior problems: Using monozygotic-twin differences to identify environmental effects on behavioral development. Developmental Psychology, 40, 149–161.

    PubMed  Google Scholar 

  • Champagne, F. A., Chretien, P., Stevenson, C. W., Zhang, T. Y., Gratton, A., & Meaney, M. J. (2004). Variations in nucleus accumbens dopamine associated with individual differences maternal behavior in the rat. Journal of Neuroscience, 24, 4113–4123.

    PubMed  Google Scholar 

  • Cheah, C. S. L., Leung, C. Y. Y., Tahseen, M., & Schultz, D. (2009). Authoritative parenting among immigrant Chinese mothers of preschoolers. Journal of Family Psychology, 23(3), 311–320.

    PubMed Central  PubMed  Google Scholar 

  • Chen, F. S., Barth, M. E., Johnson, S. L., Gotlib, I. H., & Johnson, S. C. (2011). Oxytocin receptor (OXTR) polymorphisms and attachment in human infants. Frontiers in Psychology, 2, 200–206.

    PubMed Central  PubMed  Google Scholar 

  • Cicchetti, D., Rogosch, F. A., & Toth, S. L. (2011). The effects of child maltreatment and polymorphisms of the serotonin transporter and dopamine D4 receptor genes on infant attachment and intervention efficacy. Development and Psychopathology, 23(2), 357–372.

    PubMed  Google Scholar 

  • Collins, W. A., Maccoby, E. E., Steinberg, L., Hetherington, E. M., & Bornstein, M. H. (2000). Contemporary research on parenting: The case for nature and nurture. American Psychologist, 55, 218–232.

    PubMed  Google Scholar 

  • Comings, D. E. (1998). Polygenic inheritance and micro/minisatellites. Molecular Psychiatry, 3(1), 21–32.

    PubMed  Google Scholar 

  • Comings, D. E., Gonzalez, N., Wu, S., Gade, R., Muhleman, D., Saucier, G., et al. (1999). Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse. American Journal of Medical Genetics, 88(4), 358–368.

    PubMed  Google Scholar 

  • Cummings, E. M., & Davies, P. T. (2002). Effects of marital conflict on children: recent advances and emerging themes in process-oriented research. Journal of Child Psychology and Psychiatry and Allied Disciplines, 43(1), 31–64.

    Google Scholar 

  • Deater-Deckard, K. (2000). Parenting and child behavioral adjustment in early childhood: A quantitative genetic approach to studying family processes. Child Development, 71, 468–484.

    PubMed  Google Scholar 

  • Deater-Deckard, K. (2001). Nonshared environmental processes in social-emotional development: an observational study of identical twin differences in the preschool period. Developmental Science, 4(2), F1–F6.

    Google Scholar 

  • Deater-Deckard, K., Dunn, J., O’Connor, T. G., Davies, L., & Golding, J. (2001). Using the stepfamily genetic design to examine gene-environment processes in child and family functioning. Marriage and Family Review, 33, 131–156.

    Google Scholar 

  • Deater-Deckard, K., & O’Connor, T. G. (2000). Parent–child mutuality in early childhood: Two behavioral genetic studies. Developmental Psychology, 36, 561–570.

    PubMed  Google Scholar 

  • Derijk, R. H., & de Kloet, E. R. (2008). Corticosteroid receptor polymorphims: determinants of vulnerability and resilience. European Journal of Pharmacology, 583(2–3), 303–311.

    PubMed  Google Scholar 

  • De Wolff, M. S., & van IJzendoorn, M. H. (1997). Sensitivity and attachment: A meta-analysis on parental antecedents of infant attachment. Child Development, 68, 571–591.

    Google Scholar 

  • DiLalla, L. F., & Bishop, E. G. (1996). Differential maternal treatment of infant twins: Effects of infant behaviors. Behavior Genetics, 26(6), 535–542.

    PubMed  Google Scholar 

  • DiLalla, L. F., Elam, K. K., & Smolen, A. (2009). Genetic and gene-environment interaction effects on preschoolers’ social behaviors. Developmental Psychobiology, 51(6), 451–464.

    PubMed  Google Scholar 

  • Dodge, K. A. (1990). Nature versus nurture in childhood conduct disorder: Is it time to ask a different question? Developmental Psychology, 26, 698–701.

    Google Scholar 

  • Dozier, M., Stovall, K. C., Albus, K. E., & Bates, B. (2001). Attachment for infants in foster care: The role of caregiver state of mind. Child Development, 72, 1467–1477.

    PubMed  Google Scholar 

  • Drabant, E. M., Hariri, A. R., Meyer-Lindenberg, A., Munoz, K. E., Mattay, V. S., Kolachana, B. S., et al. (2006). Catechol O-methyltransferase val(158)met genotype and neural mechanisms related to affective arousal and regulation. Archives of General Psychiatry, 63, 1396–1406.

    PubMed  Google Scholar 

  • Easterbrooks, M. A., & Goldberg, W. A. (1984). Toddler development in the family: Impact of father involvement and parenting characteristics. Child Development, 55, 740–752.

    PubMed  Google Scholar 

  • Ebstein, R. P. (2006). The molecular genetic architecture of human personality: Beyond self-report questionnaires. Molecular Psychiatry, 11, 427–445.

    PubMed  Google Scholar 

  • Elam, K. K., Harold, G. T., Neiderhiser, J. M., Reiss, D., Shaw, D. S., Natsuaki, M. N., Gaysina, D., Barrett, D., & Leve, L. D. (2013, December 23). Adoptive parent hostility and children’s peer behavior problems: Examining the role of genetically informed child attributes on adoptive parent behavior. Developmental Psychology. Advance online publication. doi: 10.1037/a0035470.

  • Enoch, M.-A., Steer, C. D., Newman, T. K., Gibson, N., & Goldman, N. (2012). Early life stress, MAOA, and gene-environment interactions predict behavioral disinhibition in children. Genes, Brain, and Behavior, 9(1), 65–74.

    Google Scholar 

  • Faraone, S. V., & Khan, S. A. (2006). Candidate gene studies of attention-deficit/hyperactivity disorder. The Journal of Clinical Psychiatry, 67(Suppl 8), 13–20.

    PubMed  Google Scholar 

  • Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005). Molecular genetics of attention-deficit/hyperactivity disorder. Biological Psychiatry, 57(11), 1313–1323.

    PubMed  Google Scholar 

  • Fearon, R. M., van IJzendoorn, M. H., Fonagy, P., Bakermans-Kranenburg, M. J., Schuengel, C., & Bokhorst, C. L. (2006). In search of shared and nonshared environmental factors in security of attachment: A behavior-genetic study of the association between sensitivity and attachment security. Developmental Psychology, 42(6), 1026–1040.

    PubMed  Google Scholar 

  • Feldman, R., Zagoory-Sharon, O., Weisman, O., Schneiderman, I., Gordon, I., Maoz, R., et al. (2012). Sensitive parenting is associated with plasma oxytocin and polymorphisms in the OXTR and CD38 genes. Biological Psychiatry, 72(3), 175–181.

    PubMed  Google Scholar 

  • Finkel, D., & Matheny, A. P. (2000). Genetic and environmental influences on a measure of infant attachment security. Twin Research, 3, 242–250.

    PubMed  Google Scholar 

  • Finkel, D., Wille, D. E., & Matheny, A. P. (1998). Preliminary results from a twin study of infant-caregiver attachment. Behavior Genetics, 28(1), 1–8.

    PubMed  Google Scholar 

  • Forget-Dubois, N., Boivin, M., Dionne, G., Pierce, T., Tremblay, R. E., & Pérusse, D. (2007). A longitudinal twin study of the genetic and environmental etiology of maternal hostile-reactive behavior during infancy and toddlerhood. Infant Behavior & Development, 30(3), 453–465.

    Google Scholar 

  • Frigerio, A., Ceppi, E., Rusconi, M., Giodra, R., Raggi, M. E., & Fearon, P. (2009). The role played by the interaction between genetic factors and attachment in the stress response in infancy. Journal of Child Psychology and Psychiatry, 50(12), 1513–1522.

    PubMed  Google Scholar 

  • Garai, E. M., Forehand, R. L., Colletti, C. J. M., Reeslund, K., Potts, J., & Compas, B. (2009). The relation of maternal sensitivity to children’s internalizing and externalizing problems within the context of maternal depressive symptoms. Behavior Modification, 33(5), 559–582.

    PubMed Central  PubMed  Google Scholar 

  • Gervai, J. (2009). Environmental and genetic influences on early attachment. Child and Adolescent Psychiatry and Mental Health, 25(3), 1–12.

    Google Scholar 

  • Gervai, J., Nemoda, Z., Lakatos, K., Ronai, Z., Toth, I., Ney, K., & Sasvari-Szekely, M. (2005). Transmission disequilibrium tests confirm the link between DRD4 gene polymorphism and infant attachment. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics, 132B(1), 126–130.

    Google Scholar 

  • Gervai, J., Novak, A., Lakatos, K., Toth, I., Danis, I., et al. (2007). Infant genotype may moderate sensitivity to maternal affective communications: Attachment disorganization, quality of care, and the DRD4 polymorphism. Social Neuroscience, 2(3–4), 307–319.

    PubMed Central  PubMed  Google Scholar 

  • Gilissen, R., Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., & Linting, M. (2008). Electrodermal reactivity during the Trier Social Stress Test for children: interaction between the serotonin transporter polymorphism and children’s attachment representation. Developmental Psychobiology, 50(6), 615–625.

    PubMed  Google Scholar 

  • Gray, C., Carter, R., & Silverman, W. (2011). Anxiety symptoms in African American Children: Relations with ethnic pride, anxiety sensitivity, and parenting. Journal of Child and Family Studies, 20(2), 205–213.

    Google Scholar 

  • Grienenberger, J., Kelly, K., & Slade, A. (2005). Maternal reflective functioning, mother-infant affective communication and infant attachment: Exploring the link between mental states and observed caregiving behavior in the intergenerational transmission of attachment. Attachment and Human Development, 7(3), 299–311.

    PubMed  Google Scholar 

  • Grossmann, K., Grossmann, K. E., Spangler, G., Suess, G., & Unzner, L. (1985). Maternal sensitivity and newborns orientation responses as related to quality of attachment in northern Germany. Monographs of the Society for Research in Child Development, 50, 233–256.

    PubMed  Google Scholar 

  • Guimond, F.-A., Brendgen, M., Forget-Dubois, N., Dionne, G., Vitaro, F., Tremblay, R. E., & Boivin, M. (2012). Associations of mother’s and father’s parenting practices with children’s observed social reticence in a competitive situation: A monozygotic twin difference study. Journal of Abnormal Child Psychology, 40(3), 391–402.

    PubMed  Google Scholar 

  • Jaffee, S. R., Caspi, A., Moffitt, T. E., Dodge, K. A., Rutter, M., Taylor, A., & Tully, L. (2005). Nature X nurture: Genetic vulnerabilities interact with child maltreatment to promote behavior problems. Development and Psychopathology, 17, 67–84.

    PubMed Central  PubMed  Google Scholar 

  • Jaffee, S. R., Caspi, A., Moffit, T. E., Polo-Tomas, M., Price, T., & Taylor, A. (2004a). The limits of child effects: Evidence for genetically mediated child effects on corporal punishment but not on physical maltreatment. Developmental Psychology, 40, 1047–1058.

    PubMed  Google Scholar 

  • Jaffee, S. R., Caspi, A., Moffitt, T. E., & Taylor, A. (2004b). Physical maltreatment victim to antisocial child: Evidence of an environmentally mediated process. Journal of Abnormal Psychology, 113, 44–55.

    PubMed  Google Scholar 

  • Kaitz, M., Shalev, I., Sapir, N., Devor, N., Samet, Y., Mankuta, D., & Ebstein, R. P. (2010). Mothers’ dopamine receptor polymorphism modulates the relation between infant fussiness and sensitive parenting. Developmental Psychobiology, 52(2), 149–157.

    PubMed  Google Scholar 

  • Kiff, C., Lengua, L., & Zalewski, M. (2011). Nature and nurturing: Parenting in the context of child temperament. Clinical Child and Family Psychology Review, 14(3), 251–301.

    PubMed Central  PubMed  Google Scholar 

  • Kim, E. (2011). Korean American parental depressive symptoms and parental acceptance-rejection and control. Issues in Mental Health Nursing, 32(2), 114–120.

    PubMed  Google Scholar 

  • Klahr, A. M., & Burt, A. S. (2013). Elucidating the etiology of individual differences in parenting: A meta-analysis of behavior genetic research. Psychological Bulletin, 140, 544–586. doi:10.1037/a0034205.

    PubMed  Google Scholar 

  • Kochanska, G., Philibert, R. A., & Barry, R. A. (2009). Interplay of genes and early mother-child relationship in the development of self-regulation from toddler to preschool age. Journal of Child Psychology and Psychiatry and Allied Disciplines, 50(11), 1331–1338.

    Google Scholar 

  • Knafo, A., & Plomin, R. (2006). Parental discipline and affection and children’s prosocial behavior: Genetic and environmental links. Journal of Personality and Social Psychology, 90(1), 147–164.

    PubMed  Google Scholar 

  • Lakatos, K., Nemoda, Z., Birkas, E., Ronai, Z., Kovacs, E., Ney, K., et al. (2003). Association of D4 dopamine receptor gene and serotonin transporter promoter polymorphisms with infants’ response to novelty. Molecular Psychiatry, 8(1), 90–98.

    PubMed  Google Scholar 

  • Lakatos, K., Nemoda, Z., Toth, I., Ronai, Z., Ney, K., Sasvari-Szekely, M., & Gervai, J. (2002). Further evidence for the role of dopamine D4 receptor (DRD4) gene in attachment disorganization: interaction of the exon III 48-bp repeat and the -521 C/T promoter polymorphisms. Molecular Psychiatry, 7(1), 27–31.

    PubMed  Google Scholar 

  • Lakatos, K., Toth, I., Nemoda, Z., Ney, K., Sasvari-Szekely, M., & Gervai, J. (2000). Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants. Molecular Psychiatry, 5(6), 633–638.

    PubMed  Google Scholar 

  • Larsson, H., Viding, E., Risjdijk, F. V., & Plomin, R. (2008). Relationships between parental negativity and childhood antisocial behavior over time: a bidirectional effects model in a longitudinal genetically informative design. Journal of Abnormal Child Psychology, 36(5), 633–645.

    PubMed  Google Scholar 

  • Lee, S. S., Chronis-Tuscano, A., Keenan, K., Pelham, W. E., Loney, J., et al. (2010). Association of maternal dopamine transporter genotype with negative parenting: Evidence for gene x environment interaction with child disruptive behavior. Molecular Psychiatry, 15, 548–558.

    PubMed  Google Scholar 

  • Lee, C.-Y. S., Lee, J., & August, G. J. (2011). Financial stress, parental depressive symptoms, parenting practices, and children’s externalizing problem behaviors: Underlying processes. Family Relations: An Interdisciplinary Journal of Applied Family Studies, 60(4), 476–490.

    Google Scholar 

  • Lesch, K.-P., & Bengel, D. (1996). Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulator. Science, 274(5292), 1527–1532.

    PubMed  Google Scholar 

  • Leve, L. D., Harold, G. T., Ge, X., Neiderhiser, J. M., Shaw, J. M., et al. (2009). Structured parenting of toddlers at high versus low genetic risk: two pathways to child problems. Journal of the American Academy of Child and Adolescent Psychiatry, 48(11), 1102–1109.

    PubMed Central  PubMed  Google Scholar 

  • Leve, L. D., Kerr, D. C. R., Shaw, D. S., Ge, X., Neiderhiser, J. M., Scaramella, L. V., et al. (2010). Infant pathways to externalizing behavior: Evidence of genotype x environment interactions. Child Development, 31, 340–356.

    Google Scholar 

  • Lieb, R., Wittchen, H.-U., Höfer, M., Fuetsch, M., Stein, M. B., & Merikangas, K. R. (2000). Parental psychopathology, parenting styles, and the risk of social phobia in offspring: A prospective-longitudinal community study. Archives of General Psychiatry, 57(9), 859–866.

    PubMed  Google Scholar 

  • Lipscomb, S. T., Leve, L. D., Shaw, D. S., Neiderhiser, J. D., et al. (2012). Negative emotionality and externalizing problems in toddlerhood: Overreactive parenting as a moderator of genetic influences. Development and Psychopathology, 24(1), 167–179.

    PubMed Central  PubMed  Google Scholar 

  • Losoya, S. H., Callor, S., Rowe, D. C., & Goldsmith, H. H. (1997). Origins of familial similarity in parenting: A study of twins and adoptive siblings. Developmental Psychology, 33(6), 1012–1023.

    PubMed  Google Scholar 

  • Lucki, I. (1998). The spectrum of behaviors influenced by serotonin. Biological Psychiatry, 44(3), 151–162.

    PubMed  Google Scholar 

  • Luijk, M. P. C. M., Roisman, G. I., Haltigan, J. D., et al. (2011a). Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects. Journal of Child Psychology and Psychiatry, 52(12), 1295–1307.

    PubMed Central  PubMed  Google Scholar 

  • Luijk, M. P. C. M., Tharner, A., Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Jaddoe, V. W., Hofman, A., et al. (2011b). The association between parenting and attachment security is moderated by a polymorphism in the mineralocorticoid receptor gene: Evidence for differential susceptibility. Biological Psychology, 88(1), 37–40.

    PubMed  Google Scholar 

  • Luijk, M. P. C. M., Velders, F. P., Tharner, A., et al. (2010). FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene–environment interaction. Psychoneuroendocrinology, 35(10), 1454–1461.

    PubMed  Google Scholar 

  • Lytton, H. (1977). Do parents create, or respond to, differences in twins? Developmental Psychology, 13(5), 456–459.

    Google Scholar 

  • Lytton, H., Martin, N. G., & Eaves, L. (1977). Environmental and genetical causes of variation in ethological aspects of behavior in two-year-old boys. Social Biology, 24(3), 200–211.

    PubMed  Google Scholar 

  • Main, M., & Goldwyn, R. (1998). Adult attachment classification system. London, UK: University College.

    Google Scholar 

  • Martini, T. S., Root, C. A., & Jenkins, J. M. (2004). Low and middle income mother’s regulation of negative emotion: Effects of children’s temperament and situational emotional responses. Social Development, 13(4), 515–530.

    Google Scholar 

  • Martins, C., & Gaffan, E. A. (2000). Effects of early maternal depression on patterns of infant-mother attachment: A meta-analytic investigation. Journal of Child Psychology and Psychiatry and Allied Disciplines, 41(6), 737–747.

    Google Scholar 

  • Matheny, A. P., Wilson, R. S., & Nuss, S. M. (1984). Toddler temperament: Stability across settings and over ages. Child Development, 55, 1200–1211.

    Google Scholar 

  • McConnell, D., Breitkreuz, D., & Savage, A. (2011). From financial hardship to child difficulties: main and moderating effects of perceived social support. Child: Care, Health and Development, 37(5), 679–691.

    Google Scholar 

  • McElwain, N. L., & Booth-LaForce, C. (2006). Maternal sensitivity to infant distress and nondistress as predictors of infant-mother attachment security. Journal of Family Psychology, 20, 247–255.

    PubMed  Google Scholar 

  • McGowan, P. O., Sasaki, A., D’Alessio, A. C., Dymov, S., Labonté, B., Szyf, M., et al. (2009). Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nature Neuroscience, 12, 342–348.

    PubMed Central  PubMed  Google Scholar 

  • McLoyd, V. C. (1998). Children in poverty: Development, public policy, and practice. In W. Damon (Ed.), Handbook of child psychology (5th ed., Vol. 4, pp. 4–135). New York, NY: Wiley.

    Google Scholar 

  • Mileva-Seitz, V., Kennedy, J., Atkinson, L., Steiner, M., Levitan, R., et al. (2011). Serotonin transporter allelic variation in mothers predicts maternal sensitivity, behavior and attitudes toward 6-month-old infants. Genes, Brain and Behavior, 10, 325–333.

    Google Scholar 

  • Mills-Koonce, W. R., Propper, C. B., Gariepy, J.-L., Blair, C., Garrett-Peters, P., & Cox, M. J. (2007). Bidirectional genetic and environmental influences of mother and child behavior: The family system as the unit of analyses. Development and Psychopathology, 19(4), 1073–1087.

    PubMed  Google Scholar 

  • Morley, T., Bailey, H., Pederson, D., & Moran, G. (2011). Exploring the development of adolescent mother-infant attachment relationships: The contribution of ecological factors”. Psychology Presentations. Paper 31. http://ir.lib.uwo.ca/psychologypres/31.

  • Murray, L. (1992). The impact of postnatal depression on infant development. Journal of Child Psychology and Psychiatry, 33, 543–561.

    PubMed  Google Scholar 

  • Nair, H., & Murray, A. D. (2005). Predictors of attachment security in preschool children from intact and divorced families. Journal of Genetic Psychology, 166(3), 245–263.

    PubMed  Google Scholar 

  • Natsuaki, M. N., Ge, X., Leve, L. D., Neiderhiser, J. D., et al. (2010). Genetic liability, environment, and the development of fussiness in toddlers: The roles of maternal depression and parental responsiveness. Developmental Psychology, 46(5), 1147–1158.

    PubMed Central  PubMed  Google Scholar 

  • Nishikawa, S., Sundbom, E., & Hägglöf, B. (2010). Influence of perceived parental rearing on adolescent self-concept and internalizing and externalizing problems in Japan. Journal of Child and Family Studies, 19(1), 57–66.

    Google Scholar 

  • Noble, E. P., Ozkaragoz, T. Z., Ritchie, T., Zhang, X., Bekin, T. R., & Sparkes, R. S. (1998). D2 and D4 dopamine receptor polymorphisms and personality. American Journal of Medical Genetics, 81, 257–267.

    PubMed  Google Scholar 

  • Numan, M. (2007). Motivational systems and the neural circuitry of maternal behavior in the rat. Developmental Psychobiology, 49, 12–21.

    PubMed  Google Scholar 

  • O’Connor, T. G., & Croft, C. M. (2000). A twin study of attachment in preschool children. Child Development, 72, 1501–1511.

    Google Scholar 

  • Oosterman, M., & Schuengel, C. (2007). Physiological effects of separation and reunion in relation to attachment and temperament in young children. Developmental Psychobiology, 49, 119–128.

    PubMed  Google Scholar 

  • Oscar-Berman, M., & Bowirrat, A. (2005). Genetic influences in emotional dysfunction and alcoholism-related brain damage. Neuropsychiatric Disease and Treatment, 1(3), 211–229.

    PubMed Central  PubMed  Google Scholar 

  • Ouellet-Morin, I., Boivin, M., Dionne, G., Lupien, S. J., Arsenault, L., Barr, R. G., et al. (2008). Variations in heritability of cortisol reactivity to stress as a function of early familial adversity among 19-month-old twins. Archives of General Psychiatry, 65(2), 211–218.

    PubMed  Google Scholar 

  • Ouellet-Morin, I., Dionne, G., Pérusse, D., Lupien, S. J., Arseneault, L., Barr, R. G., et al. (2009). Daytime cortisol secretion in 6-month-old twins: Genetic and environmental contributions as a function of early familial adversity. Biological Psychiatry, 65(5), 409–416.

    PubMed  Google Scholar 

  • Palusci, V. J., & Loeb, F. L. (2011). Risk factors and services for child maltreatment among infants and young children. Children and Youth Services Review, 33(8), 1374–1382.

    Google Scholar 

  • Parrish, J. W., Young, M. B., Perham-Hester, K. A., & Gessner, B. D. (2011). Identifying risk factors for child maltreatment in Alaska: A population-based approach. American Journal of Preventive Medicine, 40(6), 666–673.

    PubMed  Google Scholar 

  • Pauli-Pott, U., Friedel, S., Hinney, A., & Hebebrand, J. (2009). Serotonin transporter gene polymorphism (5-HTTLPR), environmental conditions, and developing negative emotionality and fear in early childhood. Journal of Neural Transmission, 116(4), 503–512.

    PubMed  Google Scholar 

  • Petrill, S. A., & Deater-Deckard, K. (2004). Task orientation, parental warmth and SES account for a significant proportion of the shared environmental variance in general cognitive ability in early childhood: Evidence from a twin study. Developmental Science, 7(1), 25–32.

    PubMed  Google Scholar 

  • Plomin, R., DeFries, J. C., & Loehlin, J. C. (1977). Genotype-environment interaction and correlation in the analysis of human behavior. Psychological Bulletin, 84(2), 309–322.

    PubMed  Google Scholar 

  • Posner, M. I., Rothbart, M. K., & Sheese, B. E. (2007). Attention genes. Developmental Science, 10(1), 24–29.

    PubMed  Google Scholar 

  • Propper, C., Moore, G. A., Mills-Koonce, W. R., Halpern, C., Hill-Soderlund, A. L., Calkins, S., et al. (2008). Gene–environment contributions to the development of infant vagal reactivity: The interaction of dopamine and maternal sensitivity. Child Development, 79, 1377–1394.

    PubMed  Google Scholar 

  • Propper, C., Willoughby, M., Halpern, C. T., Carbone, M. A., et al. (2007). Parenting quality, DRD4, and the prediction of externalizing and internalizing behaviors in early childhood. Developmental Psychobiology, 49(6), 619–632.

    PubMed  Google Scholar 

  • Putnam, S. P., Sanson, A. V., & Rothbart, M. K. (2002). Child temperament and parenting. In M. H. Bornstein (Ed.), Handbook of parenting: Vol. 1: Children and parenting (2nd ed). Mahwah, NJ: Erlbaum.

    Google Scholar 

  • Rhoades, K. A., Leve, L. D., Harold, G. T., Neiderhiser, J. D., et al. (2009). Longitudinal pathways from marital hostility to child anger during toddlerhood: genetic susceptibility and indirect effects via harsh parenting. Journal of Family Psychology: JFP: Journal of the Division of Family Psychology of the American Psychological Association (Division 43), 25(2), 282–291.

    Google Scholar 

  • Ricciuti, A. E. (1993). Child–mother attachment: A twin study. Dissertation Abstracts International, 54, 3364.

    Google Scholar 

  • Roisman, G. I., & Fraley, R. C. (2006). The limits of genetic influence: A behavior—genetic analysis of infant—caregiver relationship quality and temperament. Child Development, 77, 1656–1667.

    PubMed  Google Scholar 

  • Roisman, G. I., & Fraley, R. C. (2008). A behavior-genetic study of parenting quality, infant attachment security, and their covariation in a nationally representative sample. Developmental Psychology, 44(3), 831–839.

    PubMed  Google Scholar 

  • Rubin, K. H., Burgess, K. B., Dwyer, K. M., & Hastings, P. D. (2003). Predicting preschoolers’ externalizing behaviors from toddler temperament, conflict, and maternal negativity. Developmental Psychology, 39, 164–176.

    PubMed  Google Scholar 

  • Rutter, M., & Silberg, J. (2002). Gene-environment interplay in relation to emotional and behavioral disturbance. Annual Review of Psychology, 53, 463–490.

    PubMed  Google Scholar 

  • Scarr, S., & McCartney, K. (1983). How people make their own environments: A theory of genotype-environment effects. Child Development, 54, 424–435.

    PubMed  Google Scholar 

  • Sheese, B. E., Voelker, P. M., Rothbart, M. K., & Posner, M. I. (2007). Parenting quality interacts with genetic variation in dopamine receptor D4 to influence temperament in early childhood. Development and Psychopathology, 19, 1039–1046.

    PubMed  Google Scholar 

  • Shih, J. C., Chen, K., & Ridd, M. J. (1999). Monoamine oxidase: From genes to behavior. Annual Review of Neuroscience, 22(1), 197–218.

    PubMed Central  PubMed  Google Scholar 

  • Slade, A. (2006). Reflective parenting programs: Theory and development. Psychoanalytic Inquiry, 26, 640–657.

    Google Scholar 

  • Smolka, M. N., Schumann, G., Wrase, J., Grüsser, S. M., et al. (2005). Catechol-O-methyltransferase val 158 met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex. The Journal of Neuroscience, 25(4), 836–842.

    PubMed  Google Scholar 

  • Spangler, G., Fremmer-Bombik, E., & Grossmann, K. (1996). Social and individual determinants of infant attachment security and disorganization. Infant Mental Health Journal, 17, 127–139.

    Google Scholar 

  • Spangler, G., Johann, M., Ronai, Z., & Zimmerman, P. (2009). Genetic and environmental influence on attachment disorganization. Journal of Child Psychology and Psychiatry and Allied Disciplines, 50(8), 952–961.

    Google Scholar 

  • Spielewoy, C., Roubert, C., Hamon, M., Nosten-Bertrand, M., Betancur, C., & Giros, B. (2000). Behavioral disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice. Behavioral Pharmacology, 11, 279–290.

    Google Scholar 

  • Spinath, F. M., & O’Connor, T. G. (2003). A Behavioral Genetic Study of the Overlap Between Personality and Parenting. Journal of Personality, 71(5), 785–811.

    PubMed  Google Scholar 

  • Spokas, M., & Heimberg, R. G. (2009). Overprotective Parenting, Social Anxiety, and External Locus of Control: Cross-sectional and Longitudinal Relationships. Cognitive Therapy & Research, 33(6), 543–551.

    Google Scholar 

  • Steele, M., Hodges, J., Kaniuk, J., Hillman, S., & Henderson, K. (2003). Attachment representations and adoption: associations between maternal states of mind and emotion narratives in previously maltreated children. Journal of Child Psychotherapy, 29(2), 187–205.

    Google Scholar 

  • Steptoe, A., van Jaarzveld, C. H., Semmler, C., Plomin, R., & Wardle, J. (2009). Heritability of daytime cortisol levels and cortisol reactivity in children. Psychoneuroendocrinology, 34, 273–280.

    PubMed Central  PubMed  Google Scholar 

  • Suhara, T., Yasuno, F., Sudo, Y., Yamamoto, M., Inoue, M., Okubo, Y., & Suzuki, K. (2001). Dopamine D2 receptors in the insular cortex and the personality trait of novelty seeking. Neuroimage, 13, 891–895.

    PubMed  Google Scholar 

  • Summer, G., & Spietz, A. L. (1995). NCAST caregiver/parent-child interaction teaching manual (2nd ed.). Seattle, WA: NCAST Publications.

    Google Scholar 

  • Tarabulsy, G. M., Pascuzzo, K., Moss, E., St-Laurent, D., Bernier, A., Cyr, C., & Dubois-Comtois, K. (2008). Attachment-based intervention for maltreating families. American Journal of Orthopsychiatry, 78(3), 322–332.

    PubMed  Google Scholar 

  • Turkheimer, E., & Waldron, M. (2000). Statistical analysis, experimental method, and causal inference in developmental behavioral genetics. Human Development, 43(1), 51–52.

    Google Scholar 

  • van IJzendoorn, M. H., & Bakermans-Kranenburg, M. J. (2006). DRD47-repeat polymorphism moderates the association between maternal unresolved loss or trauma and infant disorganization. Attachment & Human Development, 8(4), 291–307.

    Google Scholar 

  • van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., & Mesman, J. (2008). Dopamine system genes associated with parenting in the context of daily hassles. Genes, Brain, and Behavior, 7(4), 403–410.

    PubMed  Google Scholar 

  • Vaughn, B. E., & Waters, E. (1990). Attachment behavior at home and in the laboratory: Q-Sort observations and strange situation classifications of one-year-olds. Child Development, 61, 1965–1973.

    PubMed  Google Scholar 

  • Verissimo, M., & Salvaterra, F. (2006). Maternal secure-base scripts and children’s attachment security in an adopted sample. Attachment & Human Development, 8, 261–273.

    Google Scholar 

  • Vondra, J. S., Sysko, J., & Belsky, J. (2005). Developmental origins of parenting: Personality and relationship factors. In T. Luster & L. Okagaki (Eds.), Parenting: An ecological perspective. Mahwah, NJ: Erlbaum.

    Google Scholar 

  • Wahlstrom, D., White, T., & Luciana, M. (2010). Neurobehavioral evidence for changes in dopamine system activity during adolescence. Neuroscience and Biobehavioral Reviews, 34, 631–648.

    PubMed Central  PubMed  Google Scholar 

  • Watson, K. K., Ghodasra, J. H., & Platt, M. L. (2009). Serotonin transporter genotype modulates social reward and punishment in rhesus macaques. PLoS ONE, 4, e4156.

    PubMed Central  PubMed  Google Scholar 

  • Zohsel, K., Buchmann, A. F., Blomeyer, D., Hohm, E., Schmidt, M. H., Esser, G., et al. (2014). Mothers’ prenatal stress and their children’s antisocial outcomes—a moderating role for the Dopamine D4 Receptor (DRD4) gene. Journal of Child Psychology and Psychiatry, 55, 69–76. doi: 10.1111/jcpp.12138.

  • Zuckerman, M. (1999). Diathesis-stress models. In M. Zuckerman (Ed.), Vulnerability to psychopathology: A biosocial model. Washington, DC: American Psychological Association.

    Google Scholar 

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Henry, J., Boivin, M., Tarabulsy, G. (2015). Gene-Environment Interplay in Parenting Young Children. In: Horwitz, B., Neiderhiser, J. (eds) Gene-Environment Interplay in Interpersonal Relationships across the Lifespan. Advances in Behavior Genetics, vol 3. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2923-8_2

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