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Practical Management of Pediatric Ocular Disorders and Strabismus pp 379–392Cite as

Retinoblastoma

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Abstract

This chapter considers general aspects and clinical features of retinoblastoma, an intraocular malignancy of primitive neuroendocrine origin that primarily affects young children. In the United States, the age-adjusted incidence of retinoblastoma is approximately 11.8 per million children aged 0–4 years, which represents 6.1 % of all childhood cancers under age 5 years. Depending on the classification of the tumor, globe-sparing treatment may be advised and should be performed by a clinician with experience in the treatment of retinoblastoma. A number of treatment options are available including local or systemic chemotherapy, chemoreduction, photocoagulation, thermotherapy, cryotherapy, brachytherapy, and enucleation. Treatment selection is complex and should be personalized to every case through a multidisciplinary approach. Genetic counseling is integral to the management of retinoblastoma patients.

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Author information

Authors and Affiliations

  1. Vitreoretinal Fellow, Bascom Palmer Eye Institute, 900 NW 17th Street, Miami, FL, 33136, USA

    Carlos A. Medina MD

  2. Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, i-20, Cleveland, OH, 44195, USA

    Priyanka Kumar MD & Arun D. Singh MD

Authors
  1. Carlos A. Medina MD
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  2. Priyanka Kumar MD
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  3. Arun D. Singh MD
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Corresponding author

Correspondence to Arun D. Singh MD .

Editor information

Editors and Affiliations

  1. Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA

    Elias Traboulsi

  2. Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital, Cincinnati, Ohio, USA

    Virginia Utz

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Medina, C.A., Kumar, P., Singh, A.D. (2016). Retinoblastoma. In: Traboulsi, E., Utz, V. (eds) Practical Management of Pediatric Ocular Disorders and Strabismus. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2745-6_37

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  • DOI: https://doi.org/10.1007/978-1-4939-2745-6_37

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2744-9

  • Online ISBN: 978-1-4939-2745-6

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