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Onconephrology pp 47–63Cite as

Glomerular Diseases Seen with Solid Tumors and Hematological Malignancies

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Abstract

Several types of cancers have been associated with various glomerular diseases. Membranous nephropathy is the most common glomerular pathology reported in patients with solid tumors. While minimal-change disease has been classically associated with Hodgkin’s lymphoma, membranoproliferative glomerulonephritis has been recognized in patients with chronic lymphocytic leukemia (CLL). Several reports and studies in the literature suggest that treating the cancer leads to resolution of the glomerular disease. This chapter reviews the association of glomerular diseases with solid tumors and hematological malignancies.

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Abbreviations

MN:

Membranous nephropathy

PLA2R:

Podocyte transmembrane glycoprotein M-type phospholipase A2 receptor

KDIGO:

Kidney Disease: Improving Global Outcomes

CT:

Computed tomography

MCD:

Minimal change disease

HIV:

Human immunodeficiency virus

ACEI:

Angiotensin converting enzyme inhibitor

ARB:

Angiotensin 2 receptor blocker

PET:

Positron emission tomography

FSGS:

Focal segmental glomerulosclerosis

HPS:

Hemophagocytic syndrome

MPN:

Myeloproliferative neoplasms

TMA:

Thrombotic microangiopathy

CML:

Chronic myelogenous leukemia

PV:

Polycythemia vera

ET:

Essential thrombocythemia

PMF:

Primary myelofibrosis

MPGN:

Membranoproliferative glomerulonephritis

CLL:

Chronic lymphocytic leukemia

MGUS:

Monoclonal gammopathy of undetermined significance

IgAN:

Immunoglobulin A nephropathy

HSP:

Henoch–Schonlein purpura

CGN:

Crescentic glomerulonephritis

ANCA:

Antineutrophil cytoplasmic antibody

FGN:

Fibrillary glomerulonephritis

ITG:

Immunotactoid glomerulopathy

AAA:

AA amyloidosis

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Authors and Affiliations

  1. Division of Kidney Diseases and Hypertension, North Shore University Hospital and Long Island Jewish Medical Center, Hofstra North Shore LIJ School of Medicine, 100 Community Drive, 2nd Floor, 11021, Great Neck, NY, USA

    Hitesh H. Shah MD

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  1. Hitesh H. Shah MD
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Correspondence to Hitesh H. Shah MD .

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Editors and Affiliations

  1. Department of Medicine, Division of Kidney Diseases and Hypertension, North Shore University Hospital and Long Island Jewish Medical Center, Hofstra North Shore LIJ School of Medicine, Great Neck, New York, USA

    Kenar D. Jhaveri

  2. Nephrology Section, General Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

    Abdulla K. Salahudeen

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Shah, H. (2015). Glomerular Diseases Seen with Solid Tumors and Hematological Malignancies. In: Jhaveri, K., Salahudeen, A. (eds) Onconephrology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2659-6_3

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  • DOI: https://doi.org/10.1007/978-1-4939-2659-6_3

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  • Print ISBN: 978-1-4939-2658-9

  • Online ISBN: 978-1-4939-2659-6

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