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Schizoaffective and Schizophreniform Disorders

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Abstract

The term “Schizoaffective Disorder” has been variously defined but has been generally applied to individuals in whom features of schizophrenia and a mood disorder coexist. Studies of phenomenology, clinical course, and heritability, have, when taken together, yielded results consistent with the view that a majority of individuals who meet criteria for schizoaffective disorder, in fact, have either schizophrenia or a mood disorder with psychotic features and that a minority suffer from a geneotypic concurrence of both illnesses. The treatment of individuals with schizoaffective disorder should initially assume the presence of a psychotic mood disorder, however.

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References

  1. Spitzer RL, Endicott J, Robins E. Research diagnostic criteria. Psychopharmacol Bull 1975;11:22–25.

    CAS  PubMed  Google Scholar 

  2. Coryell W, Endicott J, Keller M, Andreasen NC. Phenomenology and family history in DSM-III psychotic depression. J Affect Disord 1985;9:13–18.

    Article  CAS  PubMed  Google Scholar 

  3. Clayton PJ, Rodin L, Winokur G. Family history studies. 3. Schizoaffective disorder, clinical and genetic factors including a one to two year follow-up. Compr Psychiatry 1968;9:31–49.

    Article  CAS  PubMed  Google Scholar 

  4. Pope HG Jr, Lipinski JF, Cohen BM, Axelrod DT. “Schizoaffective disorder”: an invalid diagnosis? A comparison of schizoaffective disorder, schizophrenia, and affective disorder. Am J Psychiatry 1980;137:921–927.

    Article  PubMed  Google Scholar 

  5. Clayton PJ. Schizoaffective disorders. J Nerv Ment Dis 1982;170:646–650.

    Article  CAS  PubMed  Google Scholar 

  6. Coryell W, Keller M, Lavori P, Endicott J. Affective syndromes, psychotic features, and prognosis. I. Depression. Arch Gen Psychiatry 1990;47:651–657.

    Article  CAS  PubMed  Google Scholar 

  7. Coryell W, Keller M, Lavori P, Endicott J. Affective syndromes, psychotic features, and prognosis. II. Mania. Arch Gen Psychiatry 1990;47:658–662.

    Article  CAS  PubMed  Google Scholar 

  8. Coryell W, Leon AC, Turvey C, Akiskal HS, Mueller T, Endicott J. The significance of psychotic features in manic episodes: a report from the NIMH collaborative study. J Affect Disord 2001;67:79–88.

    Article  CAS  PubMed  Google Scholar 

  9. Angst J. The etiology and nosology of endogenous depressive psychoses. Foreign Psychiatry 1973;2:1–108.

    Google Scholar 

  10. Tsuang MT, Dempsey M, Rauscher F. A study of “atypical schizophrenia”. Comparison with schizophrenia and affective disorder by sex, age of admission, precipitant, outcome, and family history. Arch Gen Psychiatry 1976;33:11157–11160.

    Article  CAS  PubMed  Google Scholar 

  11. Suslak L, Shopsin B, Silbey E, Mendlewicz J, Gershon S. Genetics of affective disorders. I. Familial incidence study of bipolar, unipolar and schizo-affective illnesses. Neuropsychobiology 1976;2:18–27.

    Article  CAS  PubMed  Google Scholar 

  12. Tsuang MT, Dempsey GM, Dvoredsky A, Struss A. A family history study of schizo-affective disorder. Biol Psychiatry 1977;12:331–338.

    CAS  PubMed  Google Scholar 

  13. Mendlewicz J, Linkowski P, Wilmotte J. Relationship between schizoaffective illness and affective disorders or schizophrenia. Morbidity risk and genetic transmission. J Affect Disord 1980;2:289–302.

    Article  CAS  PubMed  Google Scholar 

  14. Scharfetter C. Subdividing the functional psychoses: a family hereditary approach. Psychol Med 1981;11:637–640.

    Article  CAS  PubMed  Google Scholar 

  15. Baron M, Gruen R, Asnis L, Kane J. Schizoaffective illness, schizophrenia and affective disorders: morbidity risk and genetic transmission. Acta Psychiatr Scand 1982;65:253–262.

    Article  CAS  PubMed  Google Scholar 

  16. Gershon ES, DeLisi LE, Hamovit J, Nurnberger JI Jr, Maxwell ME, Schreiber J, Dauphinais D, Dingman CW 2nd, Guroff JJ. A controlled family study of chronic psychoses. Schizophrenia and schizoaffective disorder. Arch Gen Psychiatry 1988;45:328–336.

    Article  CAS  PubMed  Google Scholar 

  17. Kendler KS, McGuire M, Gruenberg AM, Walsh D. Examining the validity of DSM-III-R schizoaffective disorder and its putative subtypes in the Roscommon Family Study. Am J Psychiatry 1995;152:755–764.

    Article  CAS  PubMed  Google Scholar 

  18. Maier W, Lichtermann D, Minges J, Hallmayer J, Heun R, Benkert O, Levinson DF. Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study. Arch Gen Psychiatry 1993;50:871–883.

    Article  CAS  PubMed  Google Scholar 

  19. Taylor MA, Berenbaum SA, Jampala VC, Cloninger CR. Are schizophrenia and affective disorder related? Preliminary data from a family study. Am J Psychiatry 1993;150:278–285.

    Article  CAS  PubMed  Google Scholar 

  20. Abrams R, Taylor MA. Mania and schizo-affective disorder, main type: a comparison. Am J Psychiatry 1976;133:445–447.

    Article  CAS  PubMed  Google Scholar 

  21. Rosenthal NE, Rosenthal LN, Stallone F, Dunner DL, Fieve RR. Toward the validation of RDC schizoaffective disorder. Arch Gen Psychiatry 1980;37:804–810.

    Article  CAS  PubMed  Google Scholar 

  22. Andreasen NC. The American concept of schizophrenia. Schizophr Bull 1989;15:519–531.

    Article  CAS  PubMed  Google Scholar 

  23. Bocchetta A, Bernardi F, Garau L, Migoni M, Mulas S, Pedditzi M, Del Zompo M. Familial rates of affective illness in Sardinia with special reference to schizoaffective disorder. Eur Arch Psychiatry Clin Neurosci 1990;240:16–20.

    Article  CAS  PubMed  Google Scholar 

  24. Conus P, Abdel-Baki A, Harrigan S, Lambert M, McGorry PD, Berk M. Pre-morbid and outcome correlates of first episode mania with psychosis: is a distinction between schizoaffective and bipolar I disorder valid in the early phase of psychotic disorders? J Affect Disord 2010;126:88–95.

    Article  PubMed  Google Scholar 

  25. Coryell W, Tsuang MT. DSM-III schizophreniform disorder. Comparisons with schizophrenia and affective disorder. Arch Gen Psychiatry 1982;39:66–69.

    Article  CAS  PubMed  Google Scholar 

  26. Abrams R, Taylor MA. The importance of mood-incongruent psychotic symptoms in melancholia. J Affect Disord 1983;5:179–181.

    Article  CAS  PubMed  Google Scholar 

  27. Andreasen NC, Rice J, Endicott J, Coryell W, Grove WM, Reich T. Familial rates of affective disorder. A report from the National Institute of Mental Health Collaborative Study. Arch Gen Psychiatry 1987;44:461–469.

    Article  CAS  PubMed  Google Scholar 

  28. Coryell W, Zimmerman M. The heritability of schizophrenia and schizoaffective disorder. A family study. Arch Gen Psychiatry 1988;45:323–327.

    Article  CAS  PubMed  Google Scholar 

  29. Maj M, Starace F, Pirozzi R. A family study of DSM-III-R schizoaffective disorder, depressive type, compared with schizophrenia and psychotic and nonpsychotic major depression. Am J Psychiatry 1991;148:612–616.

    Article  CAS  PubMed  Google Scholar 

  30. Coryell W, Tsuang MT, McDaniel J. Psychotic features in major depression. Is mood congruence important? J Affect Disord 1982;4:227–236.

    Article  CAS  PubMed  Google Scholar 

  31. Post RM, Uhde TW. Carbamazepine in bipolar illness. Psychopharmacol Bull 1985;21:10–17.

    CAS  PubMed  Google Scholar 

  32. Kendler KS, Gruenberg AM, Tsuang MT. Psychiatric illness in first-degree relatives of schizophrenic and surgical control patients. A family study using DSM-III criteria. Arch Gen Psychiatry 1985;42:770–779.

    Article  CAS  PubMed  Google Scholar 

  33. Cohen SM, Allen MG, Pollin W, Hrubec Z. Relationship of schizo-affective psychosis to manic depressive psychosis and schizophrenia. Findings in 15,909 veteran pairs. Arch Gen Psychiatry 1972;26:539–546.

    Article  CAS  PubMed  Google Scholar 

  34. Tsuang MT. Genetics of affective disorder. New York: Spectrum; 1975.

    Google Scholar 

  35. Cardno AG, Rijsdijk FV, Sham PC, Murray RM, McGuffin P. A twin study of genetic relationships between psychotic symptoms. Am J Psychiatry 2002;159:539–545.

    Article  PubMed  Google Scholar 

  36. Cardno AG, Sham PC, Farmer AE, Murray RM, McGuffin P. Heritability of Schneider’s first-rank symptoms. Br J Psychiatry 2002;180:35–38.

    Article  PubMed  Google Scholar 

  37. Laursen TM, Labouriau R, Licht RW, Bertelsen A, Munk-Olsen T, Mortensen PB. Family history of psychiatric illness as a risk factor for schizoaffective disorder: a Danish register-based cohort study. Arch Gen Psychiatry 2005;62:841–848.

    Article  PubMed  Google Scholar 

  38. Maziade M, Roy MA, Chagnon YC, Cliche D, Fournier JP, Montgrain N, Dion C, Lavallée JC, Garneau Y, Gingras N, Nicole L, Pirès A, Ponton AM, Potvin A, Wallot H, Mérette C. Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families. Mol Psychiatry 2005;10:486–499.

    Article  CAS  PubMed  Google Scholar 

  39. Wildenauer DB, Schwab SG, Maier W, Detera-Wadleigh SD. Do schizophrenia and affective disorder share susceptibility genes? Schizophr Res 1999;39:107–111. discussion 60.

    Article  CAS  PubMed  Google Scholar 

  40. Kendler KS, Gruenberg AM, Tsuang MT. A DSM-III family study of the nonschizophrenic psychotic disorders. Am J Psychiatry 1986;143:1098–1105.

    Article  CAS  PubMed  Google Scholar 

  41. Brockington IF, Leff JP. Schizo-affective psychosis: definitions and incidence. Psychol Med 1979;9:91–99.

    Article  CAS  PubMed  Google Scholar 

  42. Regier DA, Myers JK, Kramer M, Robins LN, Blazer DG, Hough RL, Eaton WW, Locke BZ. The NIMH Epidemiologic Catchment Area program. Historical context, major objectives, and study population characteristics. Arch Gen Psychiatry 1984;41:934–941.

    Article  CAS  PubMed  Google Scholar 

  43. Weissman MM, Myers JK. Affective disorders in a US urban community: the use of research diagnostic criteria in an epidemiological survey. Arch Gen Psychiatry 1978;35:1304–1311.

    Article  CAS  PubMed  Google Scholar 

  44. Vernon SW, Roberts RE. Use of the SADS-RDC in a tri-ethnic community survey. Arch Gen Psychiatry 1982;39:47–52.

    Article  CAS  PubMed  Google Scholar 

  45. Coryell W, Tsuang MT. Outcome after 40 years in DSM-III schizophreniform disorder. Arch Gen Psychiatry 1986;43:324–328.

    Article  CAS  PubMed  Google Scholar 

  46. Coryell W, Tsuang MT. Major depression with mood-congruent or mood-incongruent psychotic features: outcome after 40 years. Am J Psychiatry 1985;142:479–482.

    Article  CAS  PubMed  Google Scholar 

  47. Dysken MW, Kooser JA, Haraszti JS, Davis JM. Clinical usefulness of sodium amobarbital interviewing. Arch Gen Psychiatry 1979;36:789–794.

    Article  CAS  PubMed  Google Scholar 

  48. Angst J, Weis P, Grof P, Baastrup PC, Schou M. Lithium prophylaxis in recurrent affective disorders. Br J Psychiatry 1970;116:604–614.

    Article  CAS  PubMed  Google Scholar 

  49. Himmelhoch JM, Fuchs CZ, May SJ, Symons BJ, Neil JF. When a schizoaffective diagnosis has meaning. J Nerv Ment Dis 1981;169:277–282.

    Article  CAS  PubMed  Google Scholar 

  50. Johnson G. Differential response to lithium carbonate in manic depressive and schizo-affective disorders. Dis Nerv Syst 1970;31:613–615.

    CAS  PubMed  Google Scholar 

  51. Tsuang D, Coryell W. An 8-year follow-up of patients with DSM-III-R psychotic depression, schizoaffective disorder, and schizophrenia. Am J Psychiatry 1993;150:1182–1188.

    Article  CAS  PubMed  Google Scholar 

  52. Zall H, Therman PG, Myers JM. Lithium carbonate: a clinical study. Am J Psychiatry 1968;125:549–555.

    Article  CAS  PubMed  Google Scholar 

  53. Angst J. Course of unipolar depressive, bipolar manic-depressive, and schizoaffective disorders. Results of a prospective longitudinal study (author’s transl). Fortschr Neurol Psychiatr Grenzgeb 1980;48:3–30.

    Article  CAS  PubMed  Google Scholar 

  54. Moller HJ, Schmid-Bode W, Cording-Tommel C, Wittchen HU, Zaudig M, von Zerssen D. Psychopathological and social outcome in schizophrenia versus affective/schizoaffective psychoses and prediction of poor outcome in schizophrenia. Results from a 5–8 year follow-up. Acta Psychiatr Scand 1988;77:379–389.

    Article  CAS  PubMed  Google Scholar 

  55. Grossman LS, Harrow M, Goldberg JF, Fichtner CG. Outcome of schizoaffective disorder at two long-term follow-ups: comparisons with outcome of schizophrenia and affective disorders. Am J Psychiatry 1991;148:1359–1365.

    Article  CAS  PubMed  Google Scholar 

  56. Williams PV, McGlashan TH. Schizoaffective psychosis. I. Comparative long-term outcome. Arch Gen Psychiatry 1987;44:130–137.

    Article  CAS  PubMed  Google Scholar 

  57. Moller HJ, Bottlender R, Wegner U, Wittmann J, Strauss A. Long-term course of schizophrenic, affective and schizoaffective psychosis: focus on negative symptoms and their impact on global indicators of outcome. Acta Psychiatr Scand Suppl. 2000:54–57.

    Google Scholar 

  58. Sim K, Chan YH, Chong SA, Siris SG. A 24-month prospective outcome study of first-episode schizophrenia and schizoaffective disorder within an early psychosis intervention program. J Clin Psychiatry 2007;68:1368–1376.

    Article  PubMed  Google Scholar 

  59. Brockington IF, Wainwright S, Kendell RE. Manic patients with schizophrenic or paranoid symptoms. Psychol Med 1980;10:73–83.

    Article  CAS  PubMed  Google Scholar 

  60. van Praag HM, Nijo L. About the course of schizoaffective psychoses. Compr Psychiatry 1984;25:9–22.

    Article  PubMed  Google Scholar 

  61. Grossman LS, Harrow M, Fudala JL, Meltzer HY. The longitudinal course of schizoaffective disorders. A prospective follow-up study. J Nerv Ment Dis 1984;172:140–149.

    Article  CAS  PubMed  Google Scholar 

  62. Maj M, Arena F, Lovero N, Pirozzi R, Kemali D. Factors associated with response to lithium prophylaxis in DSM III major depression and bipolar disorder. Pharmacopsychiatry 1985;18:309–313.

    Article  CAS  PubMed  Google Scholar 

  63. Marneros A, Deister A, Rohde A. The concept of distinct but voluminous groups of bipolar and unipolar diseases. I. Bipolar diseases. Eur Arch Psychiatry Clin Neurosci 1990;240:77–84.

    Article  CAS  PubMed  Google Scholar 

  64. Tohen M, Tsuang MT, Goodwin DC. Prediction of outcome in mania by mood-congruent or mood-incongruent psychotic features. Am J Psychiatry 1992;149:1580–1584.

    Article  CAS  PubMed  Google Scholar 

  65. Marneros A, Rottig S, Rottig D, Tscharntke A, Brieger P. Bipolar I disorder with mood-incongruent psychotic symptoms: a comparative longitudinal study. Eur Arch Psychiatry Clin Neurosci 2009;259:131–136.

    Article  PubMed  Google Scholar 

  66. Moller HJ, Jager M, Riedel M, Obermeier M, Strauss A, Bottlender R. The Munich 15-year follow-up study (MUFUSSAD) on first-hospitalized patients with schizophrenic or affective disorders: comparison of psychopathological and psychosocial course and outcome and prediction of chronicity. Eur Arch Psychiatry Clin Neurosci 2010;260:367–384.

    Article  PubMed  Google Scholar 

  67. Schöttle D, Schimmelmann BG, Conus P, Cotton SM, Michel C, McGorry PD, Karow A, Naber D, Lambert M. Differentiating schizoaffective and bipolar I disorder in first-episode psychotic mania. Schizophr Res 2012;140:31–36.

    Article  PubMed  Google Scholar 

  68. Brockington IF, Kendell RE, Wainwright S. Depressed patients with schizophrenic or paranoid symptoms. Psychol Med 1980;10:665–675.

    Article  CAS  PubMed  Google Scholar 

  69. Coryell W, Zimmerman M. Demographic, historical, and symptomatic features of the nonmanic psychoses. J Nerv Ment Dis 1986;174:585–592.

    Article  CAS  PubMed  Google Scholar 

  70. Opjordsmoen S. Long-term course and outcome in unipolar affective and schizoaffective psychoses. Acta Psychiatr Scand 1989;79:317–326.

    Article  CAS  PubMed  Google Scholar 

  71. Marneros A, Rohde A, Deister A. The concept of distinct but voluminous groups of bipolar and unipolar diseases. II. Unipolar diseases. Eur Arch Psychiatry Clin Neurosci 1990;240:85–89.

    Article  CAS  PubMed  Google Scholar 

  72. Kendler KS. Mood-incongruent psychotic affective illness. A historical and empirical review. Arch Gen Psychiatry 1991;48:362–369.

    Article  CAS  PubMed  Google Scholar 

  73. Conus P, Abdel-Baki A, Harrigan S, Lambert M, McGorry PD. Schneiderian first rank symptoms predict poor outcome within first episode manic psychosis. J Affect Disord 2004;81:259–268.

    Article  PubMed  Google Scholar 

  74. Maj M. Lithium prophylaxis of schizoaffective disorders: a prospective study. J Affect Disord 1988;14:129–135.

    Article  CAS  PubMed  Google Scholar 

  75. Schou M, Juel-Nielsen N, Stromgren E, Voldby H. The treatment of manic psychoses by the administration of lithium salts. J Neurol Neurosurg Psychiatry 1954;17:250–260.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  76. Baastrup PC, Schou M. Lithium as a prophylactic agents. Its effect against recurrent depressions and manic-depressive psychosis. Arch Gen Psychiatry 1967;16:162–172.

    Article  CAS  PubMed  Google Scholar 

  77. Aronoff MS, Epstein RS. Factors associated with poor response to lithium carbonate: a clinical study. Am J Psychiatry 1970;127:472–480.

    Article  CAS  PubMed  Google Scholar 

  78. Prien RF, Caffey EM Jr, Klett CJ. Factors associated with treatment success in lithium carbonate prophylaxis. Report of the Veterans Administration and National Institute of Mental Health collaborative study group. Arch Gen Psychiatry 1974;31:189–192.

    Article  CAS  PubMed  Google Scholar 

  79. Yazici O, Kora K, Ucok A, Tunali D, Turan N. Predictors of lithium prophylaxis in bipolar patients. J Affect Disord 1999;55:133–142.

    Article  CAS  PubMed  Google Scholar 

  80. Sharma RP, Pandey GN, Janicak PG, Peterson J, Comaty JE, Davis JM. The effect of diagnosis and age on the DST: a metaanalytic approach. Biol Psychiatry 1988;24:555–568.

    Article  CAS  PubMed  Google Scholar 

  81. Altamura C, Guercetti G, Percudani M. Dexamethasone suppression test in positive and negative schizophrenia. Psychiatry Res 1989;30:69–75.

    Article  CAS  PubMed  Google Scholar 

  82. Newcomer JW, Faustman WO, Whiteford HA, Moses Jr JA, Csernansky JG. Symptomatology and cognitive impairment associate independently with post-dexamethasone cortisol concentrations in unmedicated schizophrenic patients. Biol Psychiatry 1991;29:855–864.

    Article  CAS  PubMed  Google Scholar 

  83. Saffer D, Metcalfe M, Coppen A. Abnormal dexamethasone suppression test in type II schizophrenia. Br J Psychiatry 1985;147:721–723.

    Article  CAS  PubMed  Google Scholar 

  84. Tandon R, Mazzara C, DeQuardo J, Craig KA, Meador-Woodruff JH, Goldman R, Greden JF. Dexamethasone suppression test in schizophrenia: relationship to symptomatology, ventricular enlargement, and outcome. Biol Psychiatry 1991;29:953–964.

    Article  CAS  PubMed  Google Scholar 

  85. Coryell W, Tsuang D. Hypothalamic–pituitary–adrenal axis hyperactivity and psychosis: recovery during an 8-year follow-up. Am J Psychiatry 1992;149:1033–1039.

    Article  CAS  PubMed  Google Scholar 

  86. Coryell WH, Zimmerman M. HPA axis hyperactivity and recovery from functional psychoses. Am J Psychiatry 1989;146:473–477.

    Article  CAS  PubMed  Google Scholar 

  87. Coryell W, Zimmermann M, Winokur G, Cadoret R. Baseline neuroendocrine function and diagnostic stability among patients with a nonmanic psychosis. Eur Arch Psychiatry Neurol Sci 1988;237:197–199.

    Article  CAS  PubMed  Google Scholar 

  88. Maj M, Starace F, Kemali D. Prediction of outcome by historical, clinical and biological variables in schizoaffective disorder, depressed type. J Psychiatr Res 1987;21:289–295.

    Article  CAS  PubMed  Google Scholar 

  89. Lewis DA, Smith RE. Steroid-induced psychiatric syndromes. A report of 14 cases and a review of the literature. J Affect Disord 1983;5:319–332.

    Article  CAS  PubMed  Google Scholar 

  90. Yago KB, Pitts Jr FN, Burgoyne RW, Aniline O, Yago LS, Pitts AF. The urban epidemic of phencyclidine (PCP) use: clinical and laboratory evidence from a public psychiatric hospital emergency service. J Clin Psychiatry 1981;42:193–196.

    CAS  PubMed  Google Scholar 

  91. Flor-Henry P. Psychosis and temporal lobe epilepsy. A controlled investigation. Epilepsia 1969;10:363–395.

    Article  CAS  PubMed  Google Scholar 

  92. Slater E, Beard AW, Glithero E. The schizophrenia-like psychoses of epilepsy. Br J Psychiatry 1963;109:95–150.

    Article  CAS  PubMed  Google Scholar 

  93. Farahani A, Correll CU. Are antipsychotics or antidepressants needed for psychotic depression? A systematic review and meta-analysis of trials comparing antidepressant or antipsychotic monotherapy with combination treatment. J Clin Psychiatry 2012;73:486–496.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  94. Keller MB, Shapiro RW, Lavori PW, Wolfe N. Relapse in major depressive disorder: analysis with the life table. Arch Gen Psychiatry 1982;39:911–915.

    Article  CAS  PubMed  Google Scholar 

  95. Dunner DL, Stallone F, Fieve RR. Prophylaxis with lithium carbonate: an update. Arch Gen Psychiatry 1982;39:1344–1345.

    CAS  PubMed  Google Scholar 

  96. Langfeldt G. The schizophreniform states. London: Oxford University Press; 1939.

    Google Scholar 

  97. Langfeldt G. Definition of “schizophreniform psychoses”. Am J Psychiatry 1982;139:703.

    CAS  PubMed  Google Scholar 

  98. Beiser M, Fleming JA, Iacono WG, Lin TY. Refining the diagnosis of schizophreniform disorder. Am J Psychiatry 1988;145:695–700.

    Article  CAS  PubMed  Google Scholar 

  99. Guldberg CA, Dahl AA, Hansen H, Bergem M. Predictive value of the four good prognostic features in DSM-III-R schizophreniform disorder. Acta Psychiatr Scand 1990;82:23–25.

    Article  CAS  PubMed  Google Scholar 

  100. Helzer JE, Brockington IF, Kendell RE. Predictive validity of DSM-III and Feighner definitions of schizophrenia. A comparison with research diagnosis criteria and CATEGO. Arch Gen Psychiatry 1981;38:791–797.

    Article  CAS  PubMed  Google Scholar 

  101. Targum SD. Neuroendocrine dysfunction in schizophreniform disorder: correlation with six-month clinical outcome. Am J Psychiatry 1983;140:309–313.

    Article  CAS  PubMed  Google Scholar 

  102. Weinberger DR, DeLisi LE, Perman GP, Targum S, Wyatt RJ. Computed tomography in schizophreniform disorder and other acute psychiatric disorders. Arch Gen Psychiatry 1982;39:778–783.

    Article  CAS  PubMed  Google Scholar 

  103. Makanjuola RO, Adedapo SA. The DSM-III concepts of schizophrenic disorder and schizophreniform disorder. A clinical and prognostic evaluation. Br J Psychiatry 1987;151:611–618.

    Article  CAS  PubMed  Google Scholar 

  104. Kendler KS, Walsh D. Schizophreniform disorder, delusional disorder and psychotic disorder not otherwise specified: clinical features, outcome and familial psychopathology. Acta Psychiatr Scand 1995;91:370–378.

    Article  CAS  PubMed  Google Scholar 

  105. Fennig S, Kovasznay B, Rich C, Ram R, Pato C, Miller A, Rubinstein J, Carlson G, Schwartz JE, Phelan J. Six-month stability of psychiatric diagnoses in first-admission patients with psychosis. Am J Psychiatry 1994;151:1200–1208.

    Article  CAS  PubMed  Google Scholar 

  106. Schimmelmann BG, Conus P, Edwards J, McGorry PD, Lambert M. Diagnostic stability 18 months after treatment initiation for first-episode psychosis. J Clin Psychiatry 2005;66:1239–1246.

    Article  PubMed  Google Scholar 

  107. Whitty P, Clarke M, McTigue O, Browne S, Kamali M, Larkin C, O’Callaghan E. Diagnostic stability four years after a first episode of psychosis. Psychiatr Serv 2005;56:1084–1088.

    Article  PubMed  Google Scholar 

  108. Naz B, Bromet EJ, Mojtabai R. Distinguishing between first-admission schizophreniform disorder and schizophrenia. Schizophr Res 2003;62:51–58.

    Article  PubMed  Google Scholar 

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Coryell, W. (2016). Schizoaffective and Schizophreniform Disorders. In: Fatemi, S., Clayton, P. (eds) The Medical Basis of Psychiatry. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2528-5_7

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