Abstract
You, as an assistant professor, are invited to participate in a multicenter trial evaluating a new antiemetic. You are not aware of all the advantages and disadvantages of multicenter trials. But you do know that if you are the principal investigator (PI) in a multicenter trial, you have full control of the study execution and you will be the first author. It is well known that these trials generate a lot of research dollars. The funds go mainly to pay several research nurses to help do the study. The excess money is often used for other unfunded studies.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
White PF. The importance of transparency in industry-sponsored multicenter clinical studies. Anesth Analg. 2007;105:1861.
Gan TJ, Apfel CC, Kovac A, Philip BK, Singla N, Minkowitz H, Habib AS, Carides A, Horgan KJ, Evans JK, Lawsson FC. The importance of transparency in industry-sponsored multicenter clinical studies. Anesth Analg. 2007;105:1861–2.
Saidman LJ. Unresolved issues relating to peer review, industry support of research, and conflict of interest. Anesthesiology. 1994;80:491–2.
Peterson FJ. Industry support of research and conflict of interest. Anesthesiology. 1994;81:270.
Eger EI. Motivation, bias and scientific integrity. Anesthesiology. 1994;81:270–1.
Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Hojgaard L, Horton R, Nicholls MG, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship and accountability. Lancet. 2001;358:854–6.
Brennan TA, Rothman DJ, Blank L, Blumenthal D, Chimonas SC, Cohen JJ, Goldman J, Kassirer JP, Kimball H, Naughton J, Smelser N. Health industry practices that create conflicts of interest: a policy proposal for academic medical centers. JAMA. 2006;295:429–33.
Newcombe JP, Kerridge IH. Assessment of human research ethics committees of potential conflicts of interest arising from pharmaceutical sponsorship of clinical research. Intern Med J. 2007;37:12–7.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer Science+Business Media New York
About this chapter
Cite this chapter
Brock-Utne, J.G. (2015). Case 33: Multicenter Trials. In: Clinical Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2516-2_33
Download citation
DOI: https://doi.org/10.1007/978-1-4939-2516-2_33
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4939-2515-5
Online ISBN: 978-1-4939-2516-2
eBook Packages: MedicineMedicine (R0)