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Analgesic Effects of Botulinum Neurotoxins: Data from Animal Studies

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Botulinum Toxin Treatment of Pain Disorders

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Abstract

The availability of novel technologies has been crucial in the discovery and description of new pain receptors and modulators expanding our knowledge of the pathophysiology of pain. Data generated from animal models indicate that botulinum toxins can modify and subdue a variety of mechanisms that generate or maintain pain.

The first part of this chapter provides a brief overview of the pathophysiology of pain in light of some of the new developments. The second part provides a focused review of the literature on how botulinum neurotoxins improve and modify animals’ response to pain as well as the therapeutic influence of these toxins on pain receptors, channels, and mediators.

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Authors and Affiliations

  1. Botulinum Toxin Treatment Program, Yale School of Medicine, New Haven, CT, USA

    Bahman Jabbari (Professor of Neurology and Director)

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  1. Bahman Jabbari
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Jabbari, B. (2015). Analgesic Effects of Botulinum Neurotoxins: Data from Animal Studies. In: Botulinum Toxin Treatment of Pain Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2501-8_2

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  • DOI: https://doi.org/10.1007/978-1-4939-2501-8_2

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2500-1

  • Online ISBN: 978-1-4939-2501-8

  • eBook Packages: MedicineMedicine (R0)

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