Abstract
Assessing bleeding risk for patients who are to undergo spinal/epidural or peripheral joint injections is patient dependent. As a physician through years of practice, you will encounter patients with varying medical comorbidities that can affect their susceptibility to bleed with spinal injections. It is important to keep an open line of communication with the physicians managing their medical bleeding conditions to determine the safest way to proceed.
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Abbreviations
- aPTT:
-
activated partial thromboplastin time
- DDAVP:
-
Desmopressin
- GP:
-
Glycoproteins
- HELLP:
-
H (hemolysis, which is the breaking down of red blood cells) EL (elevated liver enzymes) LP (low platelet count)
- INR:
-
International normalized ratio
- LMWHs:
-
Low molecular weight heparins
- PLT:
-
Platelet
- PT/INR:
-
Prothrombin time/international normalized ratio
- U:
-
Factor IX loading dose
- VWD:
-
von Willebrand’s disease
- VWF:
-
von Willebrand factor
References
Abram S. Complications associated with epidural, facet joint, and sacroiliac joint injections. In: Moore R, editor. Handbook of pain and palliative care. New York: Springer; 2012. p. 247–57.
Bush K, Hillier S. A controlled study of caudal epidural injections of triamcinolone plus procaine for the management of intractable sciatica. Spine. 1991;16:572–5.
Dilke TF, Burry HC, Grahame R. Extradural corticosteroid injection in management of lumbar nerve root compression. Br Med J. 1973;2:635.
Hollander JL, Brown Jr EM, Jessar RA, et al. Hydrocortisone and cortisone injected into arthritic joints; comparative effects of and use of hydrocortisone as a local antiarthritic agent. JAMA. 1951;147(17):1629–35.
Snibbe JC, Gambardella RA. Use of injections for osteoarthritis in joints and sports activity. Clin Sports Med. 2005;24(1):83–91.
Lavelle W, Lavelle E, Lavelle L. Intra-articular Injections. Anesthesiol Clin. 2007;25:853–62.
Derby R, et al. Complications following cervical epidural steroid injections by expert interventionalists in 2003. Pain Physician. 2004;7(4):445–9.
McGrath JM, Schaefer MP, Malkamaki DM. Incidence and characteristics of complications from epidural steroid injections. Pain Med. 2011;12(5):726–31.
Karaman H, et al. The complications of transforaminal lumbar epidural steroid injections. Spine. 2011;36(13):E819–24.
Botwin KP, Baskin M, Rao S. Adverse effects of fluoroscopically guided interlaminar thoracic epidural steroid injections. Am J Phys Med Rehabil. 2006;85(1):14–23.
Benny B, Azari P, Briones D. Complications of cervical transforaminal epidural steroid injections. Am J Phys Med Rehabil. 2010;89(7):601–7.
Reid D. Complications of low back pain therapies. Tech Reg Anesth Pain Manag. 1998;2(3):147–51.
Green L, Machin SJ. Managing anticoagulated patients during neuraxial anaesthesia. Br J Haematol. 2010;149(2):195–208. doi:10.1111/j.1365-2141.2010.08094.x. Epub 2010 Feb 8.
Vandermeulen EP, Van Aken H, Vermylen J. Anticoagulants and spinal-epidural anesthesia. Anesth Analg. 1994;79(6):1165–77.
Tehranzadeh J, Mossop EP, Golshan-Momeni M. Therapeutic arthrography and bursography. Orthop Clin North Am. 2006;37:393–408.
Creamer P. Intra-articular corticosteroid treatment in osteoarthritis. Curr Opin Rheumatol. 1999;11:417–21.
Saupe N, Zanetti M, Pfirrmann CWA, Weis T, Schwenke C, Hodler J. Pain and other side effects after MR arthrography: prospective evaluation in 1085 patients. Radiology. 2009;250:830–8.
Hugo III PC, Newberg AH, Newman JS, Wetzner SM. Complications of arthrography. Semin Musculoskelet Radiol. 1998;2:345–8.
Peterson C, Hodler J. Adverse events from diagnostic and therapeutic joint injections: a literature review. Skeletal Radiol. 2011;40:5–12.
Bettencourt RB, Linder MM. Arthrocentesis and therapeutic joint injection: an overview for the primary care physician. Prim Care. 2010;37:691–702.
Horlocker TT, Wedel DJ. Infectious complications of regional anesthesia. Best Pract Res Clin Anaesthesiol. 2008;22(3):451–75.
Shanthanna H, Park J. Acute epidural haematoma following epidural steroid injection in a patient with spinal stenosis. Anaesthesia. 2011;66(9):837–9.
Reitman CA, Watters III W. Subdural hematoma after cervical epidural steroid injection. Spine. 2002;27(6):E174–6.
Jansen NW, Roosendaal G, Wenting MJ, et al. Very rapid clearance after a joint bleed in the canine knee cannot prevent adverse effects on cartilage and synovial tissue. Osteoarthritis Cartilage. 2009;17:433–40.
Solimeno L, et al. Knee arthropathy: when things go wrong. Haemophilia. 2012;18 Suppl 4:105–11.
Mannucci PM, Tuddenham EGD. The hemophilias—from royal genes to gene therapy. N Engl J Med. 2001;344(23):1773–9.
Bolton-Maggs PHB. The rare inherited coagulation disorders. Pediatr Blood Cancer. 2013;60(S1):S37–40.
Englbrecht JS, Pogatzki-Zahn EM, Zahn P. [Spinal and epidural anesthesia in patients with hemorrhagic diathesis: decisions on the brink of minimum evidence?]. Anaesthesist. 2011;60(12):1126–34. Epub 2011/08/02. Ruckenmarknahe Regionalanasthesie bei Patienten mit hamorrhagischen Diathesen : Entscheidungen am Rande des Evidenzminimums?.
Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002;346(13):995–1008.
Peterson P, Hayes TE, Arkin CF, Bovill EG, Fairweather RB, Rock Jr WA, et al. The preoperative bleeding time test lacks clinical benefit: College of American Pathologists’ and American Society of Clinical Pathologists’ position article. Arch Surg. 1998;133(2):134–9.
Close HL, Kryzer TC, Nowlin JH, Alving BM. Hemostatic assessment of patients before tonsillectomy: a prospective study. Otolaryngol Head Neck Surg. 1994;111(6):733–8. Epub 1994/12/01.
Patel IJ, Davidson JC, Nikolic B, Salazar GM, Schwartzberg MS, Walker TG, et al. Consensus guidelines for periprocedural management of coagulation status and hemostasis risk in percutaneous image-guided interventions. J Vasc Interv Radiol. 2012;23(6):727–36.
Raj PP, Shah RV, Kaye AD, Denaro S, Hoover JM. Bleeding risk in interventional pain practice: assessment, management, and review of the literature. Pain Physician. 2004;7(1):3–51. Epub 2006/07/27.
Cobos E, Cruz J-C, Day M. Etiology and management of coagulation abnormalities in the pain management patient. Curr Rev Pain. 2000;4(5):413–9.
Soliman DE, Broadman LM. Coagulation defects. Anesthesiol Clin North America. 2006;24(3):549–78.
Mannucci PM, Federici AB. Management of inherited von Willebrand disease. Best Pract Res Clin Haematol. 2001;14(2):455–62.
Aldouri M. The use of recombinant factor VIIa in controlling surgical bleeding in non-haemophiliac patients. Pathophysiol Haemost Thromb. 2002;32 Suppl 1:41–6.
Shah RV, Kaye AD. Bleeding risk and interventional pain management. Curr Opin Anaesthesiol. 2008;21(4):433–8. Epub 2008/07/29.
Sallah S, Bobzien W. Bleeding problems in patients with liver disease. Ways to manage the many hepatic effects on coagulation. Postgrad Med. 1999;106(4):187–90. Epub 1999/10/26.
DeLoughery TG. Management of bleeding with uremia and liver disease. Curr Opin Hematol. 1999;6(5):329–33. Epub 1999/09/01.
Weigert AL, Schafer AI. Uremic bleeding: pathogenesis and therapy. Am J Med Sci. 1998;316(2):94–104.
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Riolo, T., Forzani, B.R., Levchenko, A. (2015). Injections in Patients with Bleeding Risks and Comorbid Conditions. In: Sackheim, K. (eds) Pain Management and Palliative Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2462-2_36
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