Skip to main content
SpringerLink
Log in
Book cover

Dermatological Manifestations of Kidney Disease pp 97–100Cite as

Calcinosis Cutis

  • Chapter

  • 1065 Accesses

Abstract

Calcinosis cutis, or insoluble calcium salt deposition in the skin and subcutaneous tissue, results from local or systemic insults which disturb the factors regulating calcium. The condition is classified into four subtypes based on the presumed mechanism of calcium deposition: dystrophic, metastatic, iatrogenic, and idiopathic. This chapter expands on the subtype of calcification most commonly seen in renal disease: metastatic calcification.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   159.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Nassim JR, Connolly CK. Treatment of calcinosis universalis with aluminum hydroxide. Arch Dis Child. 1970;45:118–21.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Park YM, Lee SJ, Kang H, Cho SH. Large subcutaneous calcification in systemic lupus erythematosus: treatment with oral aluminum hydroxide administration followed by surgical excision. J Korean Med Sci. 1999;14:589–92.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Cukierman T, Elinav E, Korem M, Chajek-Shaul T. Low dose warfarin treatment for calcinosis in patients with systemic sclerosis. Ann Rheum Dis. 2004;63:1341–3.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Lassoued K, Saiag P, Anglade MC, Roujeau JC, Touraine RL. Failure of warfarin in treatment of calcinosis universalis. Am J Med. 1988;84:795–6.

    Article  CAS  PubMed  Google Scholar 

  5. Valdatta L, Buoro M, Thione A, et al. Idiopathic circumscripta calcinosis cutis of the knee. Dermatol Surg. 2003;29:1222–4.

    PubMed  Google Scholar 

  6. Wang WJ, Lo WL, Wong CK. Calcinosis cutis in juvenile dermatomyositis: remarkable response to aluminum hydroxide therapy. Arch Dermatol. 1988;124:1721–2.

    Article  CAS  PubMed  Google Scholar 

  7. Sparsa A, Lesaux N, Kessler E, Bonnetblanc JM, Blaise S, Lebrun-Ly V, et al. Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shock wave lithotripsy. J Am Acad Dermatol. 2005;53:263–5.

    Article  Google Scholar 

  8. Smith LH, Drach G, Hall P, Lingeman J, Preminger G, Resnick MI, Segura JW. National High Blood Pressure Education Program (NHBPEP) review paper on complications of shock wave lithotripsy for urinary calculi. Am J Med. 1991;91(6):635.

    Article  CAS  PubMed  Google Scholar 

  9. Robertson LP, Marshall RW, Hickling P. Treatment of cutaneous calcinosis in limited systemic sclerosis with minocycline. Ann Rheum Dis. 2003;62:267–9.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  10. Ruiz-Genao DP, Rios-Buceta L, Herrero L, Fraga J, Aragues M, Garcia-Diez A. Massive scrotal calcinosis. Dermatol Surg. 2002;28:745–7.

    CAS  PubMed  Google Scholar 

  11. Block GA. Prevalence and clinical consequences of elevated Ca x P product in hemodialysis patients. Clin Nephrol. 2000;54:318–24.

    CAS  PubMed  Google Scholar 

  12. Mukamel M, Horev G, Mimouni M. New insight into calcinosis of juvenile dermatomyositis: a study of composition and treatment. J Pediatr. 2001;138:763–6.

    Article  CAS  PubMed  Google Scholar 

  13. Rabens SF, Bethune JE. Disodium etidronate therapy for dystrophic cutaneous calcification. Arch Dermatol. 1975;111:357–61.

    Article  CAS  PubMed  Google Scholar 

  14. Abdallah-Lotf M, Grasland A, Vinceneux P, Sigal-Grinberg M. Regression of cutis calcinosis with diltiazem in adult dermatomyositis. Eur J Dermatol. 2005;15:102–4.

    CAS  PubMed  Google Scholar 

  15. Ichiki Y, Akiyama T, Shimozawa N, Suzuki Y, Kondo N, Kitajima Y. An extremely severe case of cutaneous calcinosis with juvenile dermatomyositis, and successful treatment with diltiazem. Br J Dermatol. 2001;144:894–7.

    Article  CAS  PubMed  Google Scholar 

  16. Vayssairat M, Hidouche D, Abdoucheli-Baudot N, Gaitz JP. Clinical significance of subcutaneous calcinosis in patients with systemic sclerosis. Does diltiazem induce its regression? Ann Rheum Dis. 1998;57:252–4.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  17. Chan AYK, Li E. Electric shock wave lithotripsy (ESWL) as a pain control measure in dermatomyositis with calcinosis cutis—old method, new discovery. Clin Rheumatol. 2005;24:172–3.

    Article  PubMed  Google Scholar 

  18. Wu JJ, Metz BJ. Calcinosis cutis of juvenile dermatomyositis treated with incision and drainage. Dermatol Surg. 2008;34:575–7.

    CAS  PubMed  Google Scholar 

  19. Cousins MA, Jones DB, Whyte MP, Monafo WW. Surgical management of calcinosis cutis universalis in systemic lupus erythematosus. Arthritis Rheum. 1997;40:570–2.

    Article  CAS  PubMed  Google Scholar 

  20. Saddic N, Mille JJ, Miller F, Clarke JT. Surgical debridement of painful fingertip calcinosis cutis in CREST syndrome. Arch Dermatol. 2009;145:212–3.

    PubMed  Google Scholar 

  21. Bottomley WW, Goodfield MJD, Sheehan-Dare RA. Digital calcification in systemic sclerosis: effective treatment with good tissue preservation using the carbon dioxide laser. Br J Dermatol. 1996;135:302–4.

    Article  CAS  PubMed  Google Scholar 

  22. Reiter N, El-Shabrawi L, Leinweber B, Berghold A, Aberer E. Calcinosis cutis: part II. Treatment options. J Am Acad Dermatol. 2011;65:15–22. quiz 23–4.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Dermatology, Massachusetts General Hospital, 345 Franklin St., Apt. 404, Cambridge, MA, 02139, USA

    Mitalee P. Christman A.B., M.D.

  2. Massachusetts General Hospital, Harvard Medical School, 50 Staniford Street, Boston, MA, 02114, USA

    Daniela Kroshinsky M.D., M.P.H.

Authors
  1. Mitalee P. Christman A.B., M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Daniela Kroshinsky M.D., M.P.H.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Daniela Kroshinsky M.D., M.P.H. .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Nelson Clinic, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

    Julia R. Nunley

  2. Department of Medicine, Section of Nephrology, University of Illinois at Chicago / Advocate Christ Medical Center, Oak Lawn, Illinois, USA

    Edgar V. Lerma

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Christman, M.P., Kroshinsky, D. (2015). Calcinosis Cutis. In: Nunley, J., Lerma, E. (eds) Dermatological Manifestations of Kidney Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2395-3_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-2395-3_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2394-6

  • Online ISBN: 978-1-4939-2395-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation