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Introduction to Pathogenic Escherichia coli

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Detection and Typing Strategies for Pathogenic Escherichia coli

Part of the book series: SpringerBriefs in Food, Health, and Nutrition ((BRIEFSFOOD))

Abstract

Escherichia coli is one of the predominant facultative anaerobes in the human gastrointestinal tract. However, several pathogenic E. coli strains have emerged that cause disease in humans. Pathogenic E. coli can be divided into intestinal pathogens causing diarrhea, and extra intestinal E. coli causing a variety of infections in both humans and animals. This review will concentrate on the E. coli pathotypes; Enterotoxigenic E. coli (ETEC), Shiga-toxin producing E. coli (STEC), which includes a subgroup known as Enterohemorrahagic E. coli (EHEC), Enteropathogenic E. coli (EPEC), Enteroaggregative E. coli (EAEC), Enteroinvasive E. coli (EIEC), and Diffusely Adherent E. coli (DAEC). The pathotypes of interest in this review are those that are associated with intestinal infections, with a particular focus on strains important for food safety and/or cause diarrheal disease. Foodborne diseases, particularly diarrheal diseases, are an important cause of morbidity and mortality and are a public health concern worldwide with STEC/EHEC group emerging as a significant cause of foodborne disease. An estimate of the global burden of foodborne disease, including E. coli, is unknown. Surveillance and outbreak investigations are vital in gaining valuable information on the epidemiology of these pathogens and identifying other “emerging” strains, which, in turn, will aid in formulating control and intervention measures with the food industry.

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References

  • Agbodaze D (1999) Verocytotoxins (Shiga-like toxins) produced by Escherichia coli: a minireview of their classification, clinical presentations and management of a heterogeneous family of cytotoxins. Comp Immunol Microbiol Infect Dis 22:221–230

    CAS  Google Scholar 

  • Ahmed N, Dobrindt U, Hacker J, Hasnain SE (2008) Genomic fluidity and pathogenic bacteria: applications in diagnostics, epidemiology and intervention. Nat Rev Microbiol 6(5):387–394

    CAS  Google Scholar 

  • Alexio JA, Aver, GP (1996) Prevalence of Enteropathogenic and Enterotoxigenic Escherichia coli in foods of animal origin in Southern Brazil. Ciencia Rural. Santa Maria 26(2):247–250

    Google Scholar 

  • Alonso MZ, Padola NL, Parma AE, Lucchesi PM (2011) Enteropathogenic Escherichia coli contamination at different stages of the chicken slaughtering process. Poult Sci 90(11):2638–2641

    CAS  Google Scholar 

  • Altekruse SF, Swerdlow DL (1996) The changing epidemiology of foodborne diseases. Am J Med Sci 311(1):23–29

    CAS  Google Scholar 

  • Althaus D, Hofer E, Corti S, Julmi A, Stephan R (2012) Bacteriological survey of ready-to-eat lettuce, fresh-cut fruit, and sprouts collected from the Swiss market. J Food Prot 75(7):1338–1341

    CAS  Google Scholar 

  • Armstrong GL, Hollingsworth J, Morris JG, Jr. (1996) Emerging foodborne pathogens: Escherichia coli O157:H7 as a model of entry of a new pathogen into the food supply of the developed world. Epidemiol Rev 18(1):29–51

    CAS  Google Scholar 

  • Arthur TM, Barkocy-Gallagher GA, Rivera-Betancourt M, Koohmaraie M (2002) Prevalence and characterization of non-O157 Shiga toxin-producing Escherichia coli on carcasses in commercial beef cattle processing plants. Appl Environ Microbiol 68(10):4847–4852

    CAS  Google Scholar 

  • Arthur TM, Brichta-Harhay DM, Bosilevac JM, Kalchayanand N, Shackelford SD, Wheeler TL, Koohmaraie M (2010) Super shedding of Escherichia coli O157:H7 by cattle and the impact on beef carcass contamination. Meat Sci 86:32–37

    Google Scholar 

  • Badri S, Fassouane A, Filliol I, Hassar M, Cohen N (2011) Detection of Shiga toxin-producing Escherichia coli in meat marketed in Casablanca (Morocco). Cell Mol Biol 57(Suppl):OL1476–1477.

    Google Scholar 

  • Barkocy-Gallagher GA, Arthur TM, Rivera-Betancourt M, Nou X, Shackelford SD, Wheeler TL, Koohmaraie M (2003) Seasonal prevalence of Shiga toxin-producing Escherichia coli, including O157:H7 and non-O157 serotypes, and Salmonella in commercial beef processing plants. J Food Prot 66(11):1978–1986

    Google Scholar 

  • Barlow RS, Mellor GE (2010) Prevalence of enterohemorrhagic Escherichia coli serotypes in Australian beef cattle. Foodborne Pathog Dis 7(10):1239–1245

    CAS  Google Scholar 

  • Barlow RS, Gobius KS, Desmarchelier PM (2006) Shiga toxin-producing Escherichia coli in ground beef and lamb cuts: results of a one-year study. Int J Food Microbiol 111(1):1–5

    CAS  Google Scholar 

  • Baylis C (2009) Raw milk and raw milk cheeses as vehicles for infection by Verocytotoxin-producing Escherichia coli. Int J Dairy Technol 62(3):293–307

    Google Scholar 

  • Beatty ME, Adcock PM, Smith SW, Quinlan K, Kamimoto LA, Rowe SY, Scott K, Conover C, Varchmin T, Bopp CA, Greene KD, Bibb B, Slutsker L, Mintz ED (2006) Epidemic diarrhea due to enterotoxigenic Escherichia coli. Clin Infect Dis 42(3):329–334.

    Google Scholar 

  • Belanger L, Garenaux A, Harel J, Boulianne M, Nadeau E, Dozois CM (2011) Escherichia coli from animal reservoirs as a potential source of human extraintestinal pathogenic E. coli. FEMS Immunol Med Microbiol 62(1):1–10

    CAS  Google Scholar 

  • Berg J, McAllister T, Bach S, Stilborn R, Hancock D, LeJeune J (2004) Escherichia coli O157:H7 excretion by commercial feedlot cattle fed either barley- or corn-based finishing diets. J Food Prot 67(4):666–671

    Google Scholar 

  • Berger CN, Sodha SV, Shaw RK, Griffin PM, Pink D, Hand P, Frankel G (2010) Fresh fruit and vegetables as vehicles for the transmission of human pathogens. Environ Microbiol 12(9):2385–2397

    Google Scholar 

  • Bernet-Camard MF, Coconnier MH, Hudault S, Servin AL (1996) Pathogenicity of the diffusely adhering strain Escherichia coli C1845: F1845 adhesin-decay accelerating factor interaction, brush border microvillus injury, and actin disassembly in cultured human intestinal epithelial cells. Infect Immun 64(6):1918–1928

    CAS  Google Scholar 

  • Best A, La Ragione RM, Sayers AR, Woodward MJ (2005) Role for flagella but not intimin in the persistent infection of the gastrointestinal tissues of specific-pathogen-free chicks by Shiga toxin-negative Escherichia coli O157:H7. Infect Immun 73(3):1836–1846

    CAS  Google Scholar 

  • Beuchat LR (2002) Ecological factors influencing survival and growth of human pathogens on raw fruits and vegetables. Microbes Infect. 4(4):413–423

    Google Scholar 

  • Blank TE, Nougaurede J-P, Donneberg MS (2002) Enteropathogenic Escherichia coli In: Donnenberg MS (ed) Escherichia coli: virulence mechanisms of a versatile pathogen. Elsevier Inc, San Diego, pp 81–118

    Google Scholar 

  • Bolton DJ (2011) Verocytotoxigenic (Shiga Toxin-Producing) Escherichia coli: virulence factors and pathogenicity in the farm to fork paradigm. Foodborne Pathog Dis 8(3):357–365

    CAS  Google Scholar 

  • Bolton DJ, Monaghan A, Byrne B, Fanning S, Sweeney T, McDowell DA (2011) Incidence and survival of non-O157 verocytotoxigenic Escherichia coli in soil. J Appl Microbiol 111(2):484–490

    CAS  Google Scholar 

  • Bosilevac JM, Koohmaraie M (2011) Prevalence and characterization of non-O157 Shiga toxin-producing Escherichia coli isolates from commercial ground beef in the United States. Appl Environ Microbiol 77(6):2103–2112

    CAS  Google Scholar 

  • Bouzari S, Jafari A, Zarepour M (2005) Distribution of virulence related genes among enteroaggregative Escherichia coli isolates: using multiplex PCR and hybridization. Infect Genet Evol 5(1):79–83

    CAS  Google Scholar 

  • Brooks HJ, Mollison BD, Bettelheim KA, Matejka K, Paterson KA, Ward VK (2001) Occurrence and virulence factors of non-O157 Shiga toxin-producing Escherichia coli in retail meat in Dunedin, New Zealand. Lett Appl Microbiol 32(2):118–122

    CAS  Google Scholar 

  • Brunder W, Karch H, Schmidt H (2006) Complete sequence of the large virulence plasmid pSFO157 of the sorbitol-fermenting enterohemorrhagic Escherichia coli O157:H- strain 3072/96. Int J Med. Microbiol 296(7):467–474

    CAS  Google Scholar 

  • Brzuszkiewicz E, Thurmer A, Schuldes J, Leimbach A, Liesegang H, Meyer FD, Boelter J, Petersen H, Gottschalk G, Daniel R (2011) Genome sequence analyses of two isolates from the recent Escherichia coli outbreak in Germany reveal the emergence of a new pathotype: Entero-Aggregative-Haemorrhagic Escherichia coli (EAHEC). Arch Microbiol 193(12):883–891

    CAS  Google Scholar 

  • Burland V, Shao Y, Perna NT, Plunkett G, Sofia HJ, Blattner FR (1998) The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7. Nucleic Acids Res 26(18):4196–4204

    CAS  Google Scholar 

  • Cagney C, Crowley H, Duffy G, Sheridan JJ, O'Brien S, Carney E, Anderson W, McDowell DA (2004) Prevalence of Escherichia coli O157:H7 in minced beef and beef burgers from butcher shops and supermarkets in the Republic of Ireland. Food Microbiol 21:203–212

    Google Scholar 

  • Callaway TR, Anderson RC, Tellez G, Rosario C, Nava GM, Eslava C, Blanco MA, Quiroz MA, Olguin A, Herradora M, Edrington TS, Genovese KJ, Harvey RB, Nisbet DJ (2004) Prevalence of Escherichia coli O157 in cattle and swine in central Mexico. J Food Prot 67(10):2274–2276.

    CAS  Google Scholar 

  • Callaway TR, Carr MA, Edrington TS, Anderson RC, Nisbet DJ (2009) Diet, Escherichia coli O157:H7, and cattle: a review after 10 years. Curr Issues Mol Biol 11(2):67–79.

    CAS  Google Scholar 

  • Campos L, Franzolin M, Trabulsi L (2004) Diarrheagenic Escherichia coli categories among the traditional enteropathogenic E. coli O serogroups—a review. Mem Inst Oswaldo Cruz, Rio de Janeiro 99(6):545–552

    Google Scholar 

  • CDC (1994) Foodborne outbreaks of Enterotoxigenic Escherichia coli—Rhode Island and New Hampshire, 1993. Morb Mortal Wkly Rep 43(5):87–88

    Google Scholar 

  • CDC (2006) Update on multi-state outbreak of E. coli O157:H7 infections from fresh spinach, October 6, 2006. http://www.cdc.gov/ecoli/2006/september/updates/100606.htm. Accessed 30 Sept 2014

  • CDC (2007) Irrigation water issues potentially related to 2006 E. coli O157:H7 in spinach outbreak. http://www.cdc.gov/nceh/ehs/Docs/Investigation_of_an_E_Coli_Outbreak_Associated_with_Dole_Pre-Packaged_Spinach.pdf. Accessed 30 Sept 2014

  • CDC (2009a) Multistate outbreak of E. coli O157:H7 infections associated with beef from Fairbank Farms. http://www.cdc.gov/ecoli/2009/1124.html. Accessed 30 Sept 2014

  • CDC (2009b) Multistate outbreak of E. coli O157:H7 infections associated with beef from JBS Swift Beef Company. http://www.cdc.gov/ecoli/2009/0701.html. Accessed 30 Sept 2014

  • CDC (2010) Investigation update: multistate outbreak of E. coli O157:H7 infections associated with cheese. http://www.cdc.gov/ecoli/2010/cheese0157/index.html. Accessed 30 Sept 2014

  • CDC (2011) Estimates of foodborne illness in the United States. http://www.cdc.gov/foodborneburden/. Accessed 30 Sept 2014

  • CDC (2012a) Multistate outbreak of Shiga Toxin-producing Escherichia coli O26 infections linked to raw clover sprouts at Jimmy John’s restaurants (final update). http://www.cdc.gov/ecoli/2012/O26-02-12/index.html. Accessed 30 Sept 2014

  • CDC (2012b) Multistate outbreak of Shiga Toxin-producing Escherichia coli O157:H7 infections linked to organic spinach and spring mix blend (final update). http://www.cdc.gov/ecoli/2012/O157H7-11-12/index.html. Accessed 30 Sept 2014

  • CDC (2013a) Multistate outbreak of Shiga toxin-producing Escherichia coli O121 infections linked to farm rich brand frozen food products (final update). http://www.cdc.gov/ecoli/2013/O121-03-13/. Accessed 30 Sept 2014

  • CDC (2013b) Multistate outbreak of Shiga toxin-producing Escherichia coli O157:H7 infections linked to ready-to-eat salads (final update). http://www.cdc.gov/ecoli/2013/o157h7-11-13/index.html. Accessed 30 Sept 2014

  • CDC (2013c) Outbreak of Escherichia coli O104:H4 infections associated with sprout consumption—Europe and North America, May-July 2011. Morb Mortal Wkly Rep 62(50):1029–1031

    Google Scholar 

  • Chapman PA, Cerdan Malo AT, Ellin M, Ashton R, Harkin (2001) Escherichia coli O157 in cattle and sheep at slaughter, on beef and lamb carcasses and in raw beef and lamb products in South Yorkshire, UK. Int J Food Microbiol 64(1–2):139–150

    CAS  Google Scholar 

  • Chaudhuri RR, Sebaihia M, Hobman JL, Webber MA, Leyton DL, Goldberg MD, Cunningham AF, Scott-Tucker A, Ferguson PR, Thomas CM, Frankel G, Tang CM, Dudley EG, Roberts IS, Rasko DA, Pallen MJ, Parkhill J, Nataro JP, Thomson NR, Henderson IR (2010) Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain O42. PloS One 5(1):e8801

    Google Scholar 

  • Chinen I, Tanaro JD, Miliwebsky E, Lound LH, Chillemi G, Ledri S, Baschkier A, Scarpin M, Manfredi E, Rivas M (2001) Isolation and characterization of Escherichia coli O157:H7 from retail meats in Argentina. J Food Prot 64(9):1346–1351

    CAS  Google Scholar 

  • Cho S, Diez-Gonzalez F, Fossler CP, Wells SJ, Hedberg CW, Kaneene JB, Ruegg PL, Warnick LD, Bender JB (2006) Prevalence of Shiga toxin-encoding bacteria and Shiga toxin-producing Escherichia coli isolates from dairy farms and county fairs. Vet Microbiol 118(3–4):289–298

    CAS  Google Scholar 

  • Clark S (2001) Diarrheagenic Escherichia coli—an emerging problem? Diagn Microbiol Infect Dis 41:93–98

    Google Scholar 

  • Clarke S, Haigh R, Freestone P, Williams P (2003) Virulence of enteropathogenic Escherichia coli, a global pathogen. Clin Microbiol Rev 16(3):365–378

    CAS  Google Scholar 

  • Coburn B, Sekirov I, Finlay BB (2007) Type III secretion systems and disease. Clin Microbiol Rev 20(4):535–549

    CAS  Google Scholar 

  • Comery R, Thanabalasuriar A, Garneau P, Portt A, Boerlin P, Reid-Smith RJ, Harel J, Manges AR, Gruenheid S (2013) Identification of potentially diarrheagenic atypical enteropathogenic Escherichia coli strains present in Canadian food animals at slaughter and in retail meats. Appl Environ Microbiol 79(12):3892–3896

    CAS  Google Scholar 

  • Conedera G, Dalvit P, Martini M, Galiero G, Gramaglia M, Goffredo E, Loffredo G, Morabito S, Ottaviani D, Paterlini F, Pezzotti G, Pisanu M, Semprini P, Caprioli A (2004) Verocytotoxin-producing Escherichia coli O157 in minced beef and dairy products in Italy. Int J Food Microbiol 96(1):67–73

    CAS  Google Scholar 

  • Cookson AL, Taylor SCS, Bennett J, Thomson-Carter F, Attwood GT (2011) Serotypes and analysis of distribution of Shiga toxin producing Escherichia coli from cattle and sheep in the lower North Island, New Zealand. NZ Vet J 54(2):78–84

    Google Scholar 

  • Coombes BK, Wickham ME, Mascarenhas M, Gruenheid S, Finlay BB, Karmali MA (2008) Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains. Appl Environ Microbiol 74(7):2153–2160

    CAS  Google Scholar 

  • Croxen MA, Law RJ, Scholz R, Keeney KM, Wlodarska M, Finlay BB (2013) Recent advances in understanding enteric pathogenic Escherichia coli. Clin Microbiol Rev 26(4):822–880

    CAS  Google Scholar 

  • Daniels NA, Neimann J, Karpati A, Parashar UD, Greene KD, Wells JG, Srivastava A, Tauxe RV, Mintz ED, Quick R (2000) Traveler’s diarrhea at sea: three outbreaks of waterborne enterotoxigenic Escherichia coli on cruise ships. J Infect Dis 181(4):1491–1495

    CAS  Google Scholar 

  • Desmarchelier P, Fegan N (2003) Enteropathogenic Escherichia coli. In: Hocking A (ed) Foodborne microorganisms of public health significance, 6th edn. Australian Institute of Food Science and Technology Incorporated, NSW Branch, Food Microbiology Group, Waterloo DC, pp 267–310.

    Google Scholar 

  • Doane CA, Pangloli P, Richards HA, Mount JR, Golden DA, Draughon FA (2007) Occurrence of Escherichia coli O157:H7 in diverse farm environments. J Food Prot 70(1):6–10.

    CAS  Google Scholar 

  • Duffy G, Burgess CM, Bolton DJ (2014) A review of factors that affect transmission and survival of verocytotoxigenic Escherichia coli in the European farm to fork beef chain. Meat Sci 97(3):375–383.

    Google Scholar 

  • EFSA (2013) Panel on Biological Hazards (BIOHAZ); Scientific Opinion on VTEC-seropathotype and scientific criteria regarding pathogenicity assessment. EFSA J 11(4):3138

    Google Scholar 

  • Ejidokun OO, Walsh A, Barnett J, Hope Y, Ellis S, Sharp MW, Paiba GA, Logan M, Willshaw GA, Cheasty T (2006) Human Vero cytotoxigenic Escherichia coli (VTEC) O157 infection linked to birds. Epidemiol Infect 134(2):421–423

    CAS  Google Scholar 

  • Elder RO, Keen JE, Siragusa GR, Barkocy-Gallagher GA, Koohmaraie M, Laegreid WW (2000) Correlation of enterohemorrhagic Escherichia coli O157 prevalence in feces, hides, and carcasses of beef cattle during processing. Proc Natl Acad Sci U S A 97(7):2999–3003

    CAS  Google Scholar 

  • Elsinghorst EA (2002) Enterotoxigenic Escherichia coli In: Donnenberg MS (ed) Escherichia coli: virulence mechanisms of a versatile pathogen. Academic, San Diego, pp 155–187

    Google Scholar 

  • Eppinger M, Daugherty S, Agrawal S, Galens K, Sengamalay N, Sadzewicz L, Tallon L, Cebula TA, Mammel MK, Feng P, Soderlund R, Tarr PI, Debroy C, Dudley EG, Fraser CM, Ravel J (2013) Whole-genome draft sequences of 26 Enterohemorrhagic Escherichia coli O157:H7 strains. Genome Announc 1(2):e0013412

    Google Scholar 

  • Erickson MC, Doyle MP (2007) Food as a vehicle for transmission of Shiga Toxin–Producing Escherichia coli. J Food Prot 740:2426–2449

    Google Scholar 

  • Escher M, Scavia G, Morabito S, Tozzoli R, Maugliani A, Cantoni S, Fracchia S, Bettati A, Casa R, Gesu GP, Torresani E, Caprioli A (2014) A severe foodborne outbreak of diarrhoea linked to a canteen in Italy caused by enteroinvasive Escherichia coli, an uncommon agent. Epidemiol Infect 13:1–8

    Google Scholar 

  • Ethelberg S, Smith B, Torpdahl M, Lisby M, Boel J, Jensen T, Molbak K (2007) An outbreak of Verocytotoxin-producing Escherichia coli O26:H11 caused by beef sausage, Denmark 2007. Euro Surveill 12(22):3208

    Google Scholar 

  • European Centre for Disease Prevention and Control, European Food Safety Authority (2011) Shiga toxin/verotoxin-producing Escherichia coli in humans, food and animals in the EU/EEA, with special reference to the German outbreak strain STEC O104. ECDC, Stockholm

    Google Scholar 

  • Eurosurveillance Editorial Team (2013) The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2011 has been published. Euro Surveill 18(15):20449

    Google Scholar 

  • Evans J, Knight H, McKendrick IJ, Stevenson H, Varo Barbudo A, Gunn GJ, Low JC (2011) Prevalence of Escherichia coli O157: H7 and serogroups O26, O103, O111 and O145 in sheep presented for slaughter in Scotland. J Med Microbiol 60(Pt 5):653–660

    Google Scholar 

  • Fegan N, Higgs G, Vanderlinde P, Desmarchelier P (2005) An investigation of Escherichia coli O157 contamination of cattle during slaughter at an abattoir. J Food Prot 68(3):451–457

    Google Scholar 

  • Ferens W, Hovde C (2011) Escherichia coli O157:H7: animal reservoir and sources of human infection. Foodborne Pathog Dis 8(4):465–487

    Google Scholar 

  • Flint JA, Van Duynhoven T, Angulo FJ, DeLong SM, Braun P, Kirk M, Scallan E, Fitzgerald M, Adak GK, Sockett P, Ellis A, Hall G, Gargouri N, Walke H, Braam P (2005) Estimating the burden of acute gastroenteritis, foodborne disease and pathogens commonly transmitted by food: an international review. J Food Safety 41:698–704

    Google Scholar 

  • Frank C, Werber D, Cramer JP, Askar M, Faber M, an der Heiden M, Bernard H, Fruth A, Prager R, Spode A, Wadl M, Zoufaly A, Jordan S, Kemper MJ, Follin P, Muller L, King LA, Rosner B, Buchholz U, Stark K, Krause G (2011) Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany. New Engl J Med 365(19):1771–1780

    CAS  Google Scholar 

  • Fratamico P, Smith J, Buchanan R (2002) Escherichia coli. In: Cliver D, Riemann H (eds) Foodborne diseases. Academic, Amsterdam, pp 79–101

    Google Scholar 

  • Fratamico PM, Yan X, Caprioli A, Esposito G, Needleman DS, Pepe T, Tozzoli R, Cortesi ML, Morabito S (2011) The complete DNA sequence and analysis of the virulence plasmid and of five additional plasmids carried by Shiga toxin-producing Escherichia coli O26:H11 strain H30. Int J Med Microbiol 301(3):192–203

    CAS  Google Scholar 

  • Gault G, Weill FX, Mariani-Kurkdjian P, Jourdan-da Silva N, King L, Aldabe B, Charron M, Ong N, Castor C, Mace M, Bingen E, Noel H, Vaillant V, Bone A, Vendrely B, Delmas Y, Combe C, Bercion R, d’Andigne E, Desjardin M, de Valk H, Rolland P (2011) Outbreak of haemolytic uraemic syndrome and bloody diarrhoea due to Escherichia coli O104:H4, south-west France, June 2011. Euro Surveill 16(26):19905

    Google Scholar 

  • Gill A, Gill CO (2010) Non-O157 verotoxigenic Escherichia coli and beef: a Canadian perspective. Can J Vet Res 74(3):161–169

    Google Scholar 

  • Grant MA, Hedberg C, Johnson R, Harris J, Logue CM, Meng J, Sofos JN, Dickson JS (2011) The significance of non-O157 Shiga toxin-producing Escherichia coli in food. Food Prot Trends Jan:33–45

    Google Scholar 

  • Greenland K, de Jager C, Heuvelink A, van der Zwaluw K, Heck M, Notermans D, van Pelt W, Friesema I (2009) Nationwide outbreak of STEC O157 infection in the Netherlands, December 2008-January 2009: continuous risk of consuming raw beef products. Euro Surveill 14(8):19129

    Google Scholar 

  • Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB (2004) Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol 51(5):1233–1249

    CAS  Google Scholar 

  • Gunn GJ, McKendrick IJ, Ternent HE, Thomson-Carter F, Foster G, Synge BA (2007) An investigation of factors associated with the prevalence of verocytotoxin producing Escherichia coli O157 shedding in Scottish beef cattle. Vet J 174(3):554–564

    CAS  Google Scholar 

  • Gyles CL (2007) Shiga toxin-producing Escherichia coli: an overview. J Anim Sci 85(13 Suppl):E45–62

    Google Scholar 

  • Harrington SM, Dudley EG, Nataro JP (2006) Pathogenesis of enteroaggregative Escherichia coli infection. FEMS Microbiol Lett 254(1):12–18

    CAS  Google Scholar 

  • Health Protection Agency UK (2011) UK E. coli O157 outbreak associated with soil on vegetables. http://www.hpa.org.uk/webw/HPAweb&HPAwebStandard/HPAweb_C/1317130880441. Accessed 22 July 2014

  • Heuvelink AE, Zwartkruis-Nahuis JT, Beumer RR, de Boer E (1999) Occurrence and survival of verocytotoxin-producing Escherichia coli O157 in meats obtained from retail outlets in The Netherlands. J Food Prot 62(10):1115–1122

    CAS  Google Scholar 

  • Ho WS, Tan LK, Ooi PT, Yeo CC, Thong KL (2013) Prevalence and characterization of verotoxigenic-Escherichia coli isolates from pigs in Malaysia. BMC Vet Res 9:109

    Google Scholar 

  • Huang DB, Nataro JP, DuPont HL, Kamat PP, Mhatre AD, Okhuysen PC, Chiang T (2006) Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis. Clin Infect Dis 43(5):556–563

    Google Scholar 

  • Hunt JM (2010) Shiga toxin-producing Escherichia coli (STEC). Clin Lab Med 30(1):21–45

    Google Scholar 

  • Hutchison ML, Walters LD, Avery SM, Synge BA, Moore A (2004) Levels of zoonotic agents in British livestock manures. Lett Appl Microbiol 39(2):207–214

    CAS  Google Scholar 

  • Hutchison ML, Walters LD, Avery SM, Munro F, Moore A (2005) Analyses of livestock production, waste storage, and pathogen levels and prevalences in farm manures. Appl Environ Microbiol 71(3):1231–1236

    CAS  Google Scholar 

  • Ihekweazu C, Carroll K, Adak B, Smith G, Pritchard GC, Gillespie IA, Verlander NQ, Harvey-Vince L, Reacher M, Edeghere O, Sultan B, Cooper R, Morgan G, Kinross PT, Boxall NS, Iversen A, Bickler G (2012) Large outbreak of verocytotoxin-producing Escherichia coli O157 infection in visitors to a petting farm in South East England, 2009. Epidemiol Infect 140(8):1400–1413

    CAS  Google Scholar 

  • Itoh Y, Nagano I, Kunishima M, Ezaki T (1997) Laboratory investigation of enteroaggregative Escherichia coli O untypeable:H10 associated with a massive outbreak of gastrointestinal illness. J Clin Microbiol 35(10):2546–2550

    CAS  Google Scholar 

  • Jaros P, Cookson AL, Campbell DM, Besser TE, Shringi S, Mackereth GF, Lim E, Lopez L, Dufour M, Marshall JC, Baker MG, Hathaway S, Prattley DJ, French NP (2013) A prospective case-control and molecular epidemiological study of human cases of Shiga toxin-producing Escherichia coli in New Zealand. BMC Infect Dis 13:450

    Google Scholar 

  • Jo MY, Kim JH, Lim JH, Kang MY, Koh HB, Park YH, Yoon DY, Chae JS, Eo SK, Lee JH (2004) Prevalence and characteristics of Escherichia coli O157 from major food animals in Korea. Int J Food Microbiol 95(1):41–49

    CAS  Google Scholar 

  • Johnson KE, Thorpe CM, Sears CL (2006) The emerging clinical importance of non-O157 Shiga toxin-producing Escherichia coli. Clin Infect Dis 43(12):1587–1595

    Google Scholar 

  • Ju W, Cao G, Rump L, Strain E, Luo Y, Timme R, Allard M, Zhao S, Brown E, Meng J (2012a) Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing. J Clin Microbiol 50(12):4123–4127

    Google Scholar 

  • Ju W, Shen J, Li Y, Toro MA, Zhao S, Ayers S, Najjar MB, Meng J (2012b) Non-O157 Shiga toxin-producing Escherichia coli in retail ground beef and pork in the Washington D.C. area. Food Microbiol 32(2):371–377

    Google Scholar 

  • Kalchayanand N, Arthur TM, Bosilevac JM, Wells JE, Wheeler TL (2013) Chromogenic agar medium for detection and isolation of Escherichia coli serogroups O26, O45, O103, O111, O121, and O145 from fresh beef and cattle feces. J Food Prot 76(2):192–199

    Google Scholar 

  • Kaper JB, Nataro JP, Mobley HL (2004) Pathogenic Escherichia coli. Nat Rev Microbiol 2(2):123–140

    CAS  Google Scholar 

  • Karch H, Tarr PI, Bielaszewska M (2005) Enterohaemorrhagic Escherichia coli in human medicine. Int J Med Microbiol 295(6–7):405–418

    CAS  Google Scholar 

  • Karch H, Denamur E, Dobrindt U, Finlay BB, Hengge R, Johannes L, Ron EZ, Tonjum T, Sansonetti PJ, Vicente M (2012) The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak. EMBO Mol Med 4(9):841–848

    CAS  Google Scholar 

  • Karmali M, Mascarenhas M, Shen S, Ziebell K, Johnson S, Reid-Smith R, Isaac-Renton J, Clark C, Rahn K, Kaper J (2003) Association of genomic O Island 122 of Escherichia coli EDL 933 with verocytotoxin-producing Escherichia coli seropathotypes that are linked to epidemic and/or serious disease. J Clin Microbiol 41(11):4930–4940

    CAS  Google Scholar 

  • Karmali MA, Gannon V, Sargeant JM (2010) Verocytotoxin-producing Escherichia coli (VTEC). Vet Microbiol 140(3–4):360–370

    CAS  Google Scholar 

  • Kaspar C, Doyle, M.E., Archer, J. (2010) White paper on non-O157:H7 Shiga toxin-producing E. coli from mean and non-meat sources. http://fri.wisc.edu/docs/pdf/FRI_Brief_NonO157STEC_4_10.pdf. Accessed 30 Sept 2014

  • Kaur P, Chakraborti A, Asea A (2010) Enteroaggregative Escherichia coli: an emerging enteric food borne pathogen. Interdiscip Perspect Infect Dis 2010:254159

    CAS  Google Scholar 

  • Keithlin J, Sargeant J, Thomas MK, Fazil A (2014) Chronic sequelae of E. coli O157: systematic review and meta-analysis of the proportion of E. coli O157 cases that develop chronic sequelae. Foodborne Pathog Dis 11(2):79–95

    Google Scholar 

  • Kijima-Tanaka M, Ishihara K, Kojima A, Morioka A, Nagata R, Kawanishi M, Nakazawa M, Tamura Y, Takahashi T (2005) A national surveillance of Shiga toxin-producing Escherichia coli in food-producing animals in Japan. J Vet Med B Infect Dis Vet Public Health 52(5):230–237

    CAS  Google Scholar 

  • King LA, Nogareda F, Weill FX, Mariani-Kurkdjian P, Loukiadis E, Gault G, Jourdan-DaSilva N, Bingen E, Mace M, Thevenot D, Ong N, Castor C, Noel H, Van Cauteren D, Charron M, Vaillant V, Aldabe B, Goulet V, Delmas G, Couturier E, Le Strat Y, Combe C, Delmas Y, Terrier F, Vendrely B, Rolland P, de Valk H (2012) Outbreak of Shiga toxin-producing Escherichia coli O104:H4 associated with organic fenugreek sprouts, France, June 2011. Clin Infect Dis 54(11):1588–1594

    CAS  Google Scholar 

  • King LJ (2012) One health and food safety. In: Institute of Medicine (ed) Improving food safety through a one health approach. vol A8. The National Academies Press, pp 218–225

    Google Scholar 

  • Kuhnert P, Dubosson CR, Roesch M, Homfeld E, Doherr MG, Blum JW (2005) Prevalence and risk-factor analysis of Shiga toxigenic Escherichia coli in faecal samples of organically and conventionally farmed dairy cattle. Vet Microbiol 109(1–2):37–45

    Google Scholar 

  • Launders N, Byrne L, Adams N, Glen K, Jenkins C, Tubin-Delic D, Locking M, Williams C, Morgan D (2013) Outbreak of Shiga toxin-producing E. coli O157 associated with consumption of watercress, United Kingdom, August to September 2013. Euro Surveill 18(44)

    Google Scholar 

  • Law D (2000) Virulence factors of Escherichia coli O157 and other Shiga toxin-producing E. coli. J Appl Microbiol 88(5):729–745

    CAS  Google Scholar 

  • Law D, Chart H (1998) Enteroaggregative Escherichia coli. J Appl Microbiol 84(5):685–697

    CAS  Google Scholar 

  • LeBlanc JJ (2003) Implication of virulence factors in Escherichia coli O157:H7 pathogenesis. Crit Rev Microbiol 29(4):277–296

    CAS  Google Scholar 

  • Lee DW, Gwack J, Youn SK (2012) Enteropathogenic Escherichia coli outbreak and its incubation period: is it short or long? Osong Public Health Res Perspect 3(1):43–47

    Google Scholar 

  • LeJeune JT, Hancock D, Wasteson Y, Skjerve E, Urdahl AM (2006) Comparison of E. coli O157 and Shiga toxin-encoding genes (stx) prevalence between Ohio, USA and Norwegian dairy cattle. Int J Food Microbiol 109(1–2):19–24

    CAS  Google Scholar 

  • Levine MM, Edelman R (1984) Enteropathogenic Escherichia coli of classic serotypes associated with infant diarrhea: epidemiology and pathogenesis. Epidemiol Rev 6:31–51

    CAS  Google Scholar 

  • Locking ME, O'Brien SJ, Reilly WJ, Wright EM, Campbell DM, Coia JE, Browning LM, Ramsay CN (2001) Risk factors for sporadic cases of Escherichia coli O157 infection: the importance of contact with animal excreta. Epidemiol Infect 127(2):215–220

    CAS  Google Scholar 

  • López-Campos G, Martínez-Suárez JV, Aguado-Urda M, López-Alonso V (2012) Introduction to foodborne diseases. In: Hartel RW (ed) Microarray detection and characterization of bacterial foodborne pathogens. Springer, New York, pp 1–10

    Google Scholar 

  • Low JC, McKendrick IJ, McKechnie C, Fenlon D, Naylor SW, Currie C, Smith DG, Allison L, Gally DL (2005) Rectal carriage of enterohemorrhagic Escherichia coli O157 in slaughtered cattle. Appl Environ Microbiol 71(1):93–97

    CAS  Google Scholar 

  • Luna-Gierke RE, Griffin PM, Gould LH, Herman K, Bopp CA, Strockbine N, Mody RK (2014) Outbreaks of non-O157 Shiga toxin-producing Escherichia coli infection: USA. Epidemiol Infect:1–11

    Google Scholar 

  • Luzader DH, Clark DE, Gonyar LA, Kendall MM (2013) EutR is a direct regulator of genes that contribute to metabolism and virulence in Enterohemorrhagic Escherichia coli O157:H7. J Bacteriol 195(21):4947–4953

    CAS  Google Scholar 

  • Mainil J (2013) Escherichia coli virulence factors. Vet Immunol Immunopathol 152(1–2):2–12

    CAS  Google Scholar 

  • Mainil JG, Daube G (2005) Verotoxigenic Escherichia coli from animals, humans and foods: who’s who? J Appl Microbiol 98(6):1332–1344

    CAS  Google Scholar 

  • Mathusa EC, Chen Y, Enache E, Hontz L (2010) Non-O157 Shiga toxin-producing Escherichia coli in foods. J Food Prot 73(9):1721–1736

    Google Scholar 

  • McDaniel TK, Jarvis KG, Donnenberg MS, Kaper JB (1995) A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc Natl Acad Sci U S A 92(5):1664–1668

    CAS  Google Scholar 

  • McGee P, Bolton DJ, Sheridan JJ, Earley B, Kelly G, Leonard N (2002) Survival of Escherichia coli O157:H7 in farm water: its role as a vector in the transmission of the organism within herds. J Appl Microbiol 93(4):706–713

    CAS  Google Scholar 

  • Mead P, Slutsker L, Dietz V, McCaig L, Bresee J, Shapiro C, Griffin P, Tauxe R (1999) Food-related illness and death in the United States. Emerg Infect Dis 5(5):607–625

    CAS  Google Scholar 

  • Mellmann A, Harmsen D, Cummings CA, Zentz EB, Leopold SR, Rico A, Prior K, Szczepanowski R, Ji Y, Zhang W, McLaughlin SF, Henkhaus JK, Leopold B, Bielaszewska M, Prager R, Brzoska PM, Moore RL, Guenther S, Rothberg JM, Karch H (2011) Prospective genomic characterization of the German enterohemorrhagic Escherichia coli O104:H4 outbreak by rapid next generation sequencing technology. PloS One 6(7):e22751

    CAS  Google Scholar 

  • Mellor GE, Besser TE, Davis MA, Beavis B, Jung W, Smith HV, Jennison AV, Doyle CJ, Chandry PS, Gobius KS, Fegan N (2013) Multilocus genotype analysis of Escherichia coli O157 isolates from Australia and the United States provides evidence of geographic divergence. Appl Environ Microbiol 79(16):5050–5058

    CAS  Google Scholar 

  • Mingle LA, Garcia DL, Root TP, Halse TA, Quinlan TM, Armstrong LR, Chiefari AK, Schoonmaker-Bopp DJ, Dumas NB, Limberger RJ, Musser KA (2012) Enhanced identification and characterization of non-O157 Shiga toxin-producing Escherichia coli: a six-year study. Foodborne Pathog Dis 9(11):1028–1036

    CAS  Google Scholar 

  • Mitsuda T, Muto T, Yamada M, Kobayashi N, Toba M, Aihara Y, Ito A, Yokota S (1998) Epidemiological study of a food-borne outbreak of enterotoxigenic Escherichia coli O25:NM by pulsed-field gel electrophoresis and randomly amplified polymorphic DNA analysis. J Clin Microbiol 36(3):652–656

    CAS  Google Scholar 

  • Monaghan A, Byrne B, Fanning S, Sweeney T, McDowell D, Bolton DJ (2013) Serotypes and virulence profiles of atypical enteropathogenic Escherichia coli (EPEC) isolated from bovine farms and abattoirs. J Appl Microbiol 114(2):595–603

    CAS  Google Scholar 

  • Nataro JP, Kaper JB (1998) Diarrheagenic Escherichia coli. Clin Microbiol Rev 11(1):142–201

    CAS  Google Scholar 

  • Nataro JP, Levine MM (1994) Escherichia coli disease in humans. In: Gyles CL (ed) Escherichia coli in domestic animals and humans. CAB International, Wallingford, pp 285–333

    Google Scholar 

  • Nataro JP, Mai V, Johnson J, Blackwelder WC, Heimer R, Tirrell S, Edberg SC, Braden CR, Glenn Morris J Jr, Hirshon JM (2006) Diarrheagenic Escherichia coli infection in Baltimore, Maryland, and New Haven, Connecticut. Clin Infect Dis 43(4):402–407

    Google Scholar 

  • Naugle AL, Holt KG, Levine P, Eckel R (2005) Food safety and inspection service regulatory testing program for Escherichia coli O157:H7 in raw ground beef. J Food Prot 68(3):462–468

    Google Scholar 

  • Neil KP, Biggerstaff G, MacDonald JK, Trees E, Medus C, Musser KA, Stroika SG, Zink D, Sotir MJ (2012) A novel vehicle for transmission of Escherichia coli O157:H7 to humans: multistate outbreak of E. coli O157:H7 infections associated with consumption of ready-to-bake commercial prepackaged cookie dough–United States, 2009. Clin Infect Dis 54(4):511–518

    Google Scholar 

  • Newell D, Koopmans M, Verhoef L, Duizer E, Aidara-Kane A, Sprong H, Opsteegh M, Langelaar M, Threfall J, Scheutz F, van der Giessen J, Kruse H (2010) Food-borne diseases—The challenges of 20 years ago still persist while new ones continue to emerge. Int J Food Microbiol 139:S3–S15.

    Google Scholar 

  • Newton HJ, Sloan J, Bulach DM, Seemann T, Allison CC, Tauschek M, Robins-Browne RM, Paton JC, Whittam TS, Paton AW, Hartland EL (2009) Shiga toxin-producing Escherichia coli strains negative for locus of enterocyte effacement. Emerg Infect Dis 15(3):372–380

    CAS  Google Scholar 

  • O’Sullivan J, Bolton DJ, Duffy G, Baylis C, Tozzoli R, Wasteson Y, Lofdahl S (2007) Methods for detection and molecular characterisation of pathogenic Escherichia coli. Pathogenic Escherichia coli Network. Teagasc, Ashtown Food Research Centre, Dublin

    Google Scholar 

  • Oporto B, Esteban JI, Aduriz G, Juste RA, Hurtado A (2008) Escherichia coli O157:H7 and non-O157 Shiga toxin-producing E. coli in healthy cattle, sheep and swine herds in Northern Spain. Zoonoses and Public Health 55(2):73–81

    CAS  Google Scholar 

  • Park S, Szonyi B, Gautam R, Nightingale K, Anciso J, Ivanek R (2012) Risk factors for microbial contamination in fruits and vegetables at the preharvest level: a systematic review. J Food Prot 75(11):2055–2081

    CAS  Google Scholar 

  • Paton A, Srimanote P, Woodrow M, Paton J (2001) Characterization of Saa, a novel autoagglutinating adhesin produced by locus of enterocyte effacement-negative shiga-toxigenic Escherichia coli strains that are virulent for humans. Infect Immun 69(11):6999–7009

    CAS  Google Scholar 

  • Phillips D, Sumner J, Alexander JF, Dutton KM (2001a) Microbiological quality of Australian beef. J Food Prot 64(5):692–696

    CAS  Google Scholar 

  • Phillips D, Sumner J, Alexander JF, Dutton KM (2001b) Microbiological quality of Australian sheep meat. J Food Prot 64(5):697–700

    CAS  Google Scholar 

  • Pierard D, De Greve H, Haesebrouck F, Mainil J (2012) O157:H7 and O104:H4 Vero/Shiga toxin-producing Escherichia coli outbreaks: respective role of cattle and humans. Vet Res 43:13

    Google Scholar 

  • Preussel K, Hohle M, Stark K, Werber D (2013) Shiga toxin-producing Escherichia coli O157 is more likely to lead to hospitalization and death than non-O157 serogroups–except O104. PloS One 8(11):e78180

    Google Scholar 

  • Qadri F, Svennerholm AM, Faruque AS, Sack RB (2005) Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention. Clin Microbiol Rev 18(3):465–483

    Google Scholar 

  • Rangel JM, Sparling PH, Crowe C, Griffin PM, Swerdlow DL (2005) Epidemiology of Escherichia coli O157:H7 outbreaks, United States, 1982–2002. Emerg Infect Dis 11(4):603–609

    Google Scholar 

  • Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, Scheutz F, Paxinos EE, Sebra R, Chin CS, Iliopoulos D, Klammer A, Peluso P, Lee L, Kislyuk AO, Bullard J, Kasarskis A, Wang S, Eid J, Rank D, Redman JC, Steyert SR, Frimodt-Moller J, Struve C, Petersen AM, Krogfelt KA, Nataro JP, Schadt EE, Waldor MK (2011) Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. N Engl J Med 365(8):709–717

    CAS  Google Scholar 

  • Reid SD, Herbelin CJ, Bumbaugh AC, Selander RK, Whittam TS (2000) Parallel evolution of virulence in pathogenic Escherichia coli. Nature 406(6791):64–67

    CAS  Google Scholar 

  • Reis MH, Vasconcelos JC, Trabulsi LR (1980) Prevalence of enterotoxigenic Escherichia coli in some processed raw food from animal origin. Appl Environ Microbiol 39(1):270–271

    CAS  Google Scholar 

  • Rosin P, Niskanen T, Palm D, Struelens M, Takkinen J (2013) Laboratory preparedness for detection and monitoring of Shiga toxin 2-producing Escherichia coli O104:H4 in Europe and response to the 2011 outbreak. Euro Surveill 18(25):20508

    Google Scholar 

  • Sack RB, Sack DA, Mehlman IJ, Orskov F, Orskov I (1977) Enterotoxigenic Escherichia coli isolated from food. J Infect Dis 135(2):313–317

    CAS  Google Scholar 

  • Sakkejha H, Byrne L, Lawson AJ, Jenkins C (2013) An update on the microbiology and epidemiology of enteropathogenic Escherichia coli in England 2010–2012. J Med Microbiol 62(10):1531–1534

    CAS  Google Scholar 

  • Samadpour M, Kubler M, Buck FC, Depavia GA, Mazengia E, Stewart J, Yang P, Alfi D (2002) Prevalence of Shiga toxin-producing Escherichia coli in ground beef and cattle feces from King County, Washington. J Food Prot 65(8):1322–1325

    Google Scholar 

  • Sargeant JM, Sanderson MW, Smith RA, Griffin DD (2003) Escherichia coli O157 in feedlot cattle feces and water in four major feeder-cattle states in the USA. Prev Vet Med 61 (2):127–135

    CAS  Google Scholar 

  • Scaletsky IC, Souza TB, Aranda KR, Okeke IN (2010) Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil. BMC Microbiol 10:25

    Google Scholar 

  • Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson M-A, Roy SL, Jones JL, Griffin PM (2011) Foodborne illness acquired in the United Sates—major pathogens. Emerg Infect Dis 17(1):7–15

    Google Scholar 

  • Scavia G, Staffolani M, Fisichella S, Striano G, Colletta S, Ferri G, Escher M, Minelli F, Caprioli A (2008) Enteroaggregative Escherichia coli associated with a foodborne outbreak of gastroenteritis. J Med Microbiol 57(9):1141–1146

    Google Scholar 

  • Scheutz F, Nielsen EM, Frimodt-Moller J, Boisen N, Morabito S, Tozzoli R, Nataro JP, Caprioli A (2011) Characteristics of the enteroaggregative Shiga toxin/verotoxin-producing Escherichia coli O104:H4 strain causing the outbreak of haemolytic uraemic syndrome in Germany, May to June 2011. Euro Surveill 16(24):19890

    Google Scholar 

  • Schmidt H, Beutin L, Karch H (1995) Molecular analysis of the plasmid-encoded hemolysin of Escherichia coli O157:H7 strain EDL 933. Infect Immun 63(3):1055–1061

    CAS  Google Scholar 

  • Servin AL (2005) Pathogenesis of Afa/Dr diffusely adhering Escherichia coli. Clin Microbiol Rev 18(2):264–292

    CAS  Google Scholar 

  • Seto EY, Soller JA, Colford JM Jr. (2007) Strategies to reduce person-to-person transmission during widespread Escherichia coli O157:H7 outbreak. Emerg Infect Dis 13(6):860–866

    Google Scholar 

  • Slayton RB, Turabelidze G, Bennett SD, Schwensohn CA, Yaffee AQ, Khan F, Butler C, Trees E, Ayers TL, Davis ML, Laufer AS, Gladbach S, Williams I, Gieraltowski LB (2013) Outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 associated with romaine lettuce consumption, 2011. PloS One 8(2):e55300

    CAS  Google Scholar 

  • Stampi S, Caprioli A, De Luca G, Quaglio P, Sacchetti R, Zanetti F (2004) Detection of Escherichia coli O157 in bovine meat products in northern Italy. Int J Food Microbiol 90(3):257–262

    Google Scholar 

  • Steiner TS, Theilman, N.M., Guerrant., R.L. (2006) Enteric Escherichia coli infections. In: Guerrant RL, Walker DH, Weller, PF (ed) Tropical infectious diseases—principles, pathogens and practice, vol 1. Churchill Livingstone, pp 201–219

    Google Scholar 

  • Talukdar PK, Rahman M, Rahman M, Nabi A, Islam Z, Hoque MM, Endtz HP, Islam MA (2013) Antimicrobial resistance, virulence factors and genetic diversity of Escherichia coli isolates from household water supply in Dhaka, Bangladesh. PloS One 8(4):e61090

    CAS  Google Scholar 

  • Tarr PI, Bilge SS, Vary JC Jr, Jelacic S, Habeeb RL, Ward TR, Baylor MR, Besser TE (2000) Iha: a novel Escherichia coli O157:H7 adherence-conferring molecule encoded on a recently acquired chromosomal island of conserved structure. Infect Immun 68(3):1400–1407

    CAS  Google Scholar 

  • Taylor WR, Schell WL, Wells JG, Choi K, Kinnunen DE, Heiser PT, Helstad AG (1982) A foodborne outbreak of enterotoxigenic Escherichia coli diarrhea. N Engl J Med 306(18):1093–1095

    CAS  Google Scholar 

  • Thomas KM, McCann MS, Collery MM, Logan A, Whyte P, McDowell DA, Duffy G (2012) Tracking verocytotoxigenic Escherichia coli O157, O26, O111, O103 and O145 in Irish cattle. Int J Food Microbiol 153(3):288–296

    CAS  Google Scholar 

  • Thomas MK, Majowicz SE, Sockett P, Fazil A, Pollari F, Dore K, Flint JA, Edge VL (2006) Estimated numbers of community cases of illness due to Salmonella, Campylobacter and verotoxigenic Escherichia coli: Pathogen-specific community rates. Can J Infect Dis Med Microbiol 17(4):229–234

    Google Scholar 

  • Torres AG, Payne SM (1997) Haem iron-transport system in enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol 23(4):825–833

    CAS  Google Scholar 

  • Trabulsi L, Keller R, Tardelli Gomes T (2002) Typical and atypical enteropathogenic Escherichia coli. Emerg Infect Dis 8 (5):508–513

    Google Scholar 

  • Trotz-Williams LA, Mercer NJ, Walters JM, Maki AM, Johnson RP (2012) Pork implicated in a Shiga toxin-producing Escherichia coli O157:H7 outbreak in Ontario, Canada. Can J Public Health 103(5):e322–326

    Google Scholar 

  • Tsen HY, Jian LZ (1998) Development and use of a multiplex PCR system for the rapid screening of heat labile toxin I, heat stable toxin II and shiga-like toxin I and II genes of Escherichia coli in water. J Appl Microbiol 84(4):585–592

    CAS  Google Scholar 

  • Tseng M, Fratamico PM, Manning SD, Funk JA (2014) Shiga toxin-producing Escherichia coli in swine: the public health perspective. Animal health research reviews/Conference of Research Workers in Animal Diseases:1–13

    Google Scholar 

  • Tubbs RC, Hurd HS, Dargatz N, Hill G (1993) Preweaning morbidity and mortality in the United States swine herd. Swine Health Prod 1:21–28

    Google Scholar 

  • Turner SM, Scott-Tucker A, Cooper LM, Henderson IR (2006) Weapons of mass destruction: virulence factors of the global killer enterotoxigenic Escherichia coli. FEMS Microbiol Lett 263(1):10–20

    CAS  Google Scholar 

  • Uhitil S, Jaksic S, Petrak T, Botka-Petrak K (2001) Presence of Escherichia coli O157:H7 in ground beef and ground baby beef meat. J Food Prot 64(6):862–864

    CAS  Google Scholar 

  • USDA-FSIS (2014) Microbiological results of raw ground beef and raw ground beef components analyzed for Escherichia coli O157:H7 and non-O157 STEC, calendar year 2012. http://www.fsis.usda.gov/wps/portal/fsis/topics/data-collection-and-reports/microbiology/ec/summary-data/summary-data. Accessed 30 Sept 2014

  • Vally H, Hall G, Dyda A, Raupach J, Knope K, Combs B, Desmarchelier P (2012) Epidemiology of Shiga toxin producing Escherichia coli in Australia, 2010. BMC Public Health 21(12):63

    Google Scholar 

  • van den Beld M, Reubsaet F (2012) Differentiation between Shigella, enteroinvasive Escherichia coli (EIEC) and noninvasive Escherichia coli. Eur J Clin Microbiol Infect Dis 31(6):899–904

    Google Scholar 

  • Vernozy-Rozand C, Ray-Gueniot S, Ragot C, Bavai C, Mazuy C, Montet MP, Bouvet J, Richard Y (2002) Prevalence of Escherichia coli O157:H7 in industrial minced beef. Lett Appl Microbiol 35(1):7–11

    CAS  Google Scholar 

  • Viazis S, Diez-Gonzalez F (2011) Enterohemorrhagic Escherichia coli: the twentieth century’s emergingfoodborne pathogen: a review. Adv Agronom 111:1–50

    CAS  Google Scholar 

  • Wang F, Yang Q, Kase JA, Meng J, Clotilde LM, Lin A, Ge B (2013a) Current trends in detecting non-O157 Shiga toxin-producing Escherichia coli in food. Foodborne Pathog Dis 10(8):665–677

    Google Scholar 

  • Wang X, Taylor M, Hoang L, Ekkert J, Nowakowski C, Stone J, Tone G, Trerise S, Paccagnella A, Wong T, Galanis E (2013b) Comparison of clinical and epidemiological features of Shiga toxin-producing Escherichia coli O157 and non-O157 infections in British Columbia, 2009 to 2011. Can J Infect Dis Med Microbiol 24(4):e102–106

    Google Scholar 

  • Wasteson Y, Johannessen GS, Bruheim T, Urdahl AM, O'Sullivan K, Rorvik LM (2005) Fluctuations in the occurrence of Escherichia coli O157:H7 on a Norwegian farm. Lett Appl Microbiol 40(5):373–377

    CAS  Google Scholar 

  • Wedley AL, Elajnef HM, Fletcher JN (2013) Characterization of a novel EAST-negative enteropathogenic E. coli strain implicated in a food-borne outbreak of diarrhoea in adults. APMIS 121(6):494–502

    CAS  Google Scholar 

  • Wells JE, Shackelford SD, Berry ED, Kalchayanand N, Bosilevac JM, Wheeler TL (2011) Impact of reducing the level of wet distillers grains fed to cattle prior to harvest on prevalence and levels of Escherichia coli O157:H7 in feces and on hides. J Food Prot 74(10):1611–1617

    CAS  Google Scholar 

  • Wells JE, Kim M, Bono JL, Kuehn LA, Benson AK (2014) Escherichia coli O157:H7, diet, and fecal microbiome in beef cattle. J Anim Sci 92(4):1345–1355

    CAS  Google Scholar 

  • Wenneras C, Erling V (2004) Prevalence of enterotoxigenic Escherichia coli-associated diarrhoea and carrier state in the developing world. J Health Popul Nutr 22(4):370–382

    Google Scholar 

  • Werber D, Fruth A, Buchholz U, Prager R, Kramer MH, Ammon A, Tschape H (2003) Strong association between shiga toxin-producing Escherichia coli O157 and virulence genes stx 2 and eae as possible explanation for predominance of serogroup O157 in patients with haemolytic uraemic syndrome. Eur J Clin Microbiol Infect Dis 22(12):726–730

    CAS  Google Scholar 

  • Wilson A, Evans J, Chart H, Cheasty T, Wheeler JG, Tompkins D, Smith HR (2001) Characterisation of strains of enteroaggregative Escherichia coli isolated during the infectious intestinal disease study in England. Eur J Epidemiol 17(12):1125–1130

    CAS  Google Scholar 

  • World Health Organisation (2008) WHO Initiative to Estimate the Global Burden of Foodborne Diseases. Paper presented at the First formal meeting of the Foodborne Disease Burden Epidemiology Reference Group (FERG), Geneva

    Google Scholar 

  • World Health Organisation (2011) Outbreaks of E. coli O104:H4 infection. http://www.euro.who.int/en/health-topics/emergencies/international-health-regulations/outbreaks-of-e.-coli-o104h4-infection. Accessed 30 Sept 2014

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  1. Institute of Environmental Science and Research, Riccarton, Christchurch, New Zealand

    Lucia Rivas

  2. CSIRO Food and Nutrition Flagship, Archerfield, Queensland, Australia

    Glen E. Mellor

  3. CSIRO Food and Nutrition Flagship, Werribee VIC, Victoria, Australia

    Kari Gobius & Narelle Fegan

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  1. Lucia Rivas
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Rivas, L., Mellor, G., Gobius, K., Fegan, N. (2015). Introduction to Pathogenic Escherichia coli . In: Detection and Typing Strategies for Pathogenic Escherichia coli. SpringerBriefs in Food, Health, and Nutrition. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2346-5_1

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