Abstract
Ampullary adenomatous lesions may present sporadically or in patients with polyposis syndromes such as FAP. The management approach for these two groups differs, with FAP lesions less likely to become malignant and thus generally surveyed over time, while sporadic lesions typically require resection. The diagnostic evaluation of these lesions involves endoscopic examination as well as radiology, histology, and newer techniques including endoscopic ultrasound and intraductal ultrasound. In sporadic adenomas, an endoscopic approach to resection involving endoscopic ampullectomy or papillotomy is increasingly being used with equivalent efficacy and decreased morbidity compared to surgical techniques including pancreaticoduodenectomy and transduodenal ampullectomy.
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Video 18.1 Endoscopic ampullectomy
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Storm, A., Thompson, C. (2015). Ampullectomy. In: Lee, L. (eds) ERCP and EUS. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2320-5_18
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