Abstract
Advanced endoscopic imaging incorporates several methods to enhance visualization of the upper gastrointestinal tract. It is an evolving field within advanced endoscopy and particularly important for the endoscopist performing ESD, as these modalities can aid all stages of ESD. Advanced imaging involves several different techniques, from chromoendoscopy (e.g. Lugol’s solution, methylene blue, indigo carmine), to optical enhancement methods (e.g. magnified endoscopy, narrow band imaging, confocal endomicroscopy) and electronic methods (e.g. spectrometry, optical coherence tomography). Frequently, a combination of techniques is utilized to maximize visualization of the lesion and surrounding mucosa. The endoscopist performing ESD needs to be familiarized with these tools. As these technologies continue to improve our visualization of the mucosa and ongoing research standardizes and validates lesion pattern recognition, it is only a matter of time before these imaging modalities become standard practice.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Qumseya BJ, Wang H, Badie N, et al. Advanced imaging technologies increase detection of dysplasia and neoplasia in patients with Barrett’s esophagus: a meta-analysis and systematic review. Clin Gastroenterol Hepatol. 2013;11:1562–70.e1-2.
Canto MI, Anandasabapathy S, Brugge W, et al. In vivo endomicroscopy improves detection of Barrett’s esophagus-related neoplasia: a multicenter international randomized controlled trial (with video). Gastrointest Endosc. 2014;79:211–21.
Jang JY. The usefulness of magnifying endoscopy and narrow-band imaging in measuring the depth of invasion before endoscopic submucosal dissection. Clin Endosc. 2012;45:379–85.
Kaltenbach T, Sano Y, Friedland S, Soetikno R. American Gastroenterological Association (AGA) Institute technology assessment on image-enhanced endoscopy. Gastroenterology. 2008;134:327–40.
Capelle LG, Haringsma J, de Vries AC, et al. Narrow band imaging for the detection of gastric intestinal metaplasia and dysplasia during surveillance endoscopy. Dig Dis Sci. 2010;55:3442–8.
Shahid MW, Buchner AM, Coron E, et al. Diagnostic accuracy of probe-based confocal laser endomicroscopy in detecting residual colorectal neoplasia after EMR: a prospective study. Gastrointest Endosc. 2012;75:525–33.
Wong Kee Song LM, Adler DG, Chand B, et al. Chromoendoscopy. Gastrointest Endosc. 2007;66:639–49.
Tanaka S, Kaltenbach T, Chayama K, Soetikno R. High-magnification colonoscopy (with videos). Gastrointest Endosc. 2006;64:604–13.
Saxena P, Canto MI. Red flag imaging techniques in Barrett’s esophagus. Gastrointest Endosc Clin N Am. 2013;23:535–47.
Sakai Y, Eto R, Kasanuki J, et al. Chromoendoscopy with indigo carmine dye added to acetic acid in the diagnosis of gastric neoplasia: a prospective comparative study. Gastrointest Endosc. 2008;68:635–41.
Yamashita H, Kitayama J, Ishigami H, et al. Endoscopic instillation of indigo carmine dye with acetic acid enables the visualization of distinct margin of superficial gastric lesion; Usefulness in endoscopic treatment and diagnosis of gastric cancer. Dig Liver Dis. 2007;39:389–91.
Buchner AM, Wallace MB. Future expectations in digestive endoscopy: competition with other novel imaging techniques. Best Pract Res Clin Gastroenterol. 2008;22:971–87.
Wolfsen HC, Crook JE, Krishna M, et al. Prospective, controlled tandem endoscopy study of narrow band imaging for dysplasia detection in Barrett’s Esophagus. Gastroenterology. 2008;135:24–31.
Sharma P, Hawes RH, Bansal A, et al. Standard endoscopy with random biopsies versus narrow band imaging targeted biopsies in Barrett’s oesophagus: a prospective, international, randomised controlled trial. Gut. 2013;62:15–21.
Li HY, Ge ZZ, Fujishiro M, Li XB. Current clinical applications of magnifying endoscopy with narrow band imaging in the stomach. Diagn Ther Endosc. 2012;2012:271914.
Kiyotoki S, Nishikawa J, Satake M, et al. Usefulness of magnifying endoscopy with narrow-band imaging for determining gastric tumor margin. J Gastroenterol Hepatol. 2010;25:1636–41.
Nagahama T, Yao K, Maki S, et al. Usefulness of magnifying endoscopy with narrow-band imaging for determining the horizontal extent of early gastric cancer when there is an unclear margin by chromoendoscopy (with video). Gastrointest Endosc. 2011;74:1259–67.
Hayashi N, Tanaka S, Hewett DG, et al. Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. Gastrointest Endosc. 2013;78:625–32.
Boerwinkel DF, Holz JA, Kara MA, et al. Effects of autofluorescence imaging on detection and treatment of early neoplasia in patients with Barrett’s esophagus. Clin Gastroenterol Hepatol. 2014;12:774.
Hanaoka N, Uedo N, Shiotani A, et al. Autofluorescence imaging for predicting development of metachronous gastric cancer after Helicobacter pylori eradication. J Gastroenterol Hepatol. 2010;25:1844–9.
Kato M, Uedo N, Ishihara R, et al. Analysis of the color patterns of early gastric cancer using an autofluorescence imaging video endoscopy system. Gastric Cancer. 2009;12:219–24.
Goetz M, Malek NP, Kiesslich R. Microscopic imaging in endoscopy: endomicroscopy and endocytoscopy. Nat Rev Gastroenterol Hepatol. 2014;11:11–8.
Kumagai Y, Kawada K, Yamazaki S, et al. Endocytoscopic observation for esophageal squamous cell carcinoma: can biopsy histology be omitted? Dis Esophagus. 2009;22:505–12.
Wallace MB, Meining A, Canto MI, et al. The safety of intravenous fluorescein for confocal laser endomicroscopy in the gastrointestinal tract. Aliment Pharmacol Ther. 2010;31:548–52.
Sharma P, Meining AR, Coron E, et al. Real-time increased detection of neoplastic tissue in Barrett’s esophagus with probe-based confocal laser endomicroscopy: final results of an international multicenter, prospective, randomized, controlled trial. Gastrointest Endosc. 2011;74:465–72.
Jeon SR, Cho WY, Jin SY, Cheon YK, Choi SR, Cho JY. Optical biopsies by confocal endomicroscopy prevent additive endoscopic biopsies before endoscopic submucosal dissection in gastric epithelial neoplasias: a prospective, comparative study. Gastrointest Endosc. 2011;74:772–80.
ASGE Technology Committee. Enhanced imaging in the GI tract: spectroscopy and optical coherence tomography. Gastrointest Endosc. 2013;78:568–73.
Georgakoudi I, Jacobson BC, Van Dam J, et al. Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett’s esophagus. Gastroenterology. 2001;120:1620–9.
Wallace MB, Perelman LT, Backman V, et al. Endoscopic detection of dysplasia in patients with Barrett’s esophagus using light-scattering spectroscopy. Gastroenterology. 2000;119:677–82.
Douplik A, Zanati S, Saiko G, et al. Diffuse reflectance spectroscopy in Barrett’s Esophagus: developing a large field-of-view screening method discriminating dysplasia from metaplasia. J Biophotonics. 2014;7:304.
Pohl J, Nguyen-Tat M, Pech O, May A, Rabenstein T, Ell C. Computed virtual chromoendoscopy for classification of small colorectal lesions: a prospective comparative study. Am J Gastroenterol. 2008;103:562–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer Science+Business Media New York
About this chapter
Cite this chapter
Berzosa, M., Wallace, M.B. (2015). Advanced Endoscopic Imaging in the Upper Gastrointestinal Tract. In: Fukami, N. (eds) Endoscopic Submucosal Dissection. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2041-9_5
Download citation
DOI: https://doi.org/10.1007/978-1-4939-2041-9_5
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4939-2040-2
Online ISBN: 978-1-4939-2041-9
eBook Packages: MedicineMedicine (R0)