Skip to main content

Prevention of Stricture Formation After Esophageal Endoscopic Submucosal Dissection

  • Chapter
Endoscopic Submucosal Dissection

Abstract

Endoscopic balloon dilatation (EBD) is a technique that is primarily performed for the prevention of postoperative strictures after endoscopic submucosal dissection (ESD) of semi-circumferential and circumferential esophageal carcinoma. This procedure is initiated early on in postoperative course. However, this imposes a long-term burden on the patient and carries the risk of perforation of the healing stricture. Local injection of a steroid drug was recently introduced, as it has been used for esophageal inflammation or after esophageal dilatation, and is injected into the resection plane as a preventive measure for postoperative strictures after ESD. With this therapy, additional EBD was unnecessary in approximately 80 % of the semi-circumferential resection cases, and it was possible to reduce the number of additional EBD for circumferential resection cases. Thus, local steroid injection therapy may be an alternative to EBD for preventing postoperative strictures.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Muto M, et al. Multicenter prospective randomized controlled study on the detection and diagnosis of superficial squamous cell carcinoma by back-to-back endoscopic examination of narrowband imaging and white light observation. Gastrointest Endosc. 2007;65:AB110.

    Google Scholar 

  2. Inoue H, Honda T, Nagai K, et al. Ultra-high magnification endoscopic observation of carcinoma in situ of the esophagus. Dig Endosc. 1997;9:16–8.

    Article  Google Scholar 

  3. Arima M, Tada M, Arima H. Evaluation of microvascular patterns of superficial esophageal cancers by magnifying endoscopy. Esophagus. 2005;4:191–7.

    Article  Google Scholar 

  4. Oyama T, Kikuchi Y. Aggressive endoscopic mucosal resection in the upper GI tract – hook knife EMR method. Min Invas Ther All Technol. 2002;11:291–5.

    Google Scholar 

  5. Japan Esophageal Association. Guidelines of diagnosis and treatment for esophageal cancer. 10th ed. Tokyo: Kanehara; 2008 (Revised version) (Japanese).

    Google Scholar 

  6. Hironaka S, Ohtsu A, Boku N, et al. Nonrandomized comparison between definitive chemoradiotherapy and radical surgery in patients with T2-3NanyM0 squamous cell carcinoma of the esophagus. Int J Radiat Oncol Biol Phys. 2003;57:425–33.

    Article  PubMed  Google Scholar 

  7. Katada C, Muto M, Manabe T, et al. Esophageal stenosis after endoscopic mucosal resection of superficial esophageal lesions. Gastrointest Endosc. 2003;57:165–9.

    Article  PubMed  Google Scholar 

  8. Hashimoto S, Kobayashi M, Takeuchi M, et al. The efficacy of endoscopic triamcinolone injection for the prevention of esophageal stricture after endoscopic submucosal dissection. Gastrointest Endosc. 2011;74:1389–93.

    Article  PubMed  Google Scholar 

  9. Inoue H, Minami H, Sato Y, et al. Technical feasibility of circumferential ESD and preventive balloon dilation. Stom Intest. 2009;44:394–7.

    Google Scholar 

  10. Takeuchi M, Kobayashi M, Oyama T, et al. Complications in ESD for early esophageal carcinoma. Stom Intest. 2009;44:384–93.

    Google Scholar 

  11. Ohki T, Yamamoto M, Murakami D, et al. Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model. Gut. 2007;56(3):313–4.

    Article  Google Scholar 

  12. Takagi R, Murakami D, Kondo M, et al. Fabrication of human oral mucosal epithelial cell sheets for treatment of esophageal ulceration by endoscopic submucosal dissection. Gastrointest Endosc. 2010;72:1253–9.

    Article  PubMed  Google Scholar 

  13. Saito Y, Tanaka T, Andoh A, et al. Novel biodegradable stents for benign esophageal strictures following endoscopic submucosal dissection. Dig Dis Sci. 2008;53(2):330–3.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Manabu Takeuchi M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Takeuchi, M. (2015). Prevention of Stricture Formation After Esophageal Endoscopic Submucosal Dissection. In: Fukami, N. (eds) Endoscopic Submucosal Dissection. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2041-9_14

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-2041-9_14

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2040-2

  • Online ISBN: 978-1-4939-2041-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics