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Microcystic Adnexal Carcinoma

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Rare Malignant Skin Tumors

Abstract

Microcystic adnexal carcinoma (MAC), first described by Goldstein et al. in 1982, represents a distinctive malignant neoplasm with an indolent, locally destructive behavior. The neoplasm has a predilection for the face and is composed of cornifying cystic structures in the upper portion, columnar and solid aggregations of pale or slightly dark eosinophilic epithelial cells in the middle, and duct-like or tubular structures in the lower part. The neoplasm manifests both sweat gland and follicular differentiation.

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Bibliography

  • Boos MD, Elenitsas R, Seykora J, et al. Benign subclinical syringomatous proliferations adjacent to a microcystic adnexal carcinoma: A tumor mimic with significant patient implications. Am J Dermatopathol 2014;36:174–8.

    Google Scholar 

  • Chiller K, Passaro D, Scheuller M, et al. Microcystic adnexal carcinoma: forty-eight cases, their treatment, and their outcome. Arch Dermatol. 2000;136:1355–9.

    CAS  PubMed  Google Scholar 

  • Pujol RM, LeBoit PE, Su WP. Microcystic adnexal carcinoma with extensive sebaceous differentiation. Am J Dermatopathol. 1997;19:358–62.

    Article  CAS  PubMed  Google Scholar 

  • Goldstein DJ, Barr RJ, Santa Cruz DJ. Microcystic adnexal carcinoma: a distinct clinicopathologic entity. Cancer. 1982;50:566–72.

    Article  CAS  PubMed  Google Scholar 

  • Requena L, Kiryu H, Ackerman A, et al. Neoplasms with apocrine differentiation. Philadelphia: Lippincott-Raven; 1998.

    Google Scholar 

  • Rongioletti F, Grosshans E, Rebora A. Microcystic adnexal carcinoma. Br J Dermatol. 1986;115:101–4.

    Article  CAS  PubMed  Google Scholar 

  • Wick MR, Cooper PH, Swanson PE, et al. Microcystic adnexal carcinoma. An immunohistochemical comparison with other cutaneous appendage tumors. Arch Dermatol. 1990;126:189–94.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Irina Margaritescu M.D., DipRCPath .

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Margaritescu, I., Chirita, A.D. (2015). Microcystic Adnexal Carcinoma. In: Rare Malignant Skin Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2023-5_22

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  • DOI: https://doi.org/10.1007/978-1-4939-2023-5_22

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2022-8

  • Online ISBN: 978-1-4939-2023-5

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