Abstract
This textbook has described innovative technologies for achieving the controlled release of therapeutic agents; such drug delivery platforms rely on advances in multiple fields, including polymer science, molecular biology, nanotechnology, and chemical engineering. Novel structures for drug delivery incorporate hydrogels, micelles, liposomes, and thin films with unique mechanical and biological properties. These structures can be designed for responsiveness to internal or external stimuli, creating “smart” environmentally triggered systems. These structures can also be modified with immunomodulating polymers, creating “stealth” systems that can circulate through the body for extended periods of time. The kinetics of drug release can be tailored to achieve zero-order, first-order, diffusion-controlled, or erosion-controlled delivery, or a combination of these mechanisms. Virtually every clinical discipline can benefit from new drug delivery strategies.
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Holowka, E.P., Bhatia, S.K. (2014). Conclusion. In: Drug Delivery. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1998-7_8
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DOI: https://doi.org/10.1007/978-1-4939-1998-7_8
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Online ISBN: 978-1-4939-1998-7
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