Abstract
Chronic abdominal pain (CAP) is a complex disorder whose optimal treatment requires an interdisciplinary team encompassing medical, interventional/surgical, and psychotherapy approaches. Current understanding of the neurophysiological, neuroanatomical, and behavioral components of CAP is still incomplete. The central focus of a successful treatment in CAP is the initial correct diagnosis of the predominant pain pathway/source. From the Pain Medicine perspective, besides a careful clinical impression and laboratory and radiological studies, it involves employing the utility of neural blocks as a diagnostic as well as a prognostic tool for subsequent neuro ablative or neuromodulatory procedures. The poorly delineated pathophysiology and variable clinical course/heterogeneity of CAP suggests that individualized strategies are required for optimal management. This overview presents a brief review of the nature and pathophysiology of CAP as well as various diagnostic approaches that have been found to be effective in Pain Medicine for treatment of CAP.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Houghton AK, Wang CC, Westlund KN. Do nociceptive signals from the pancreas travel in the dorsal column? Pain. 2001;89(2–3):207–20. Research Support, U.S. Gov’t, P.H.S.
Djouhri L, Lawson SN. Abeta-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals. Brain Res Brain Res Rev. 2004;46(2):131–45. Comparative Study Research Support, Non-U.S. Gov’t Review.
Djouhri L, Lawson SN. Differences in the size of the somatic action potential overshoot between nociceptive and non-nociceptive dorsal root ganglion neurones in the guinea-pig. Neuroscience. 2001;108(3):479–91. Research Support, Non-U.S. Gov’t.
Lawson SN. Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres. Exp Physiol. 2002;87(2):239–44. Research Support, Non-U.S. Gov’t Review.
Winnie A, Candido K. Differential neural blockade for the diagnosis of pain. In: Waldman S, editor. Pain management. Philadelphia: Saunders; 2007. p. 155–66.
Hogan QH, Abram SE. Neural blockade for diagnosis and prognosis. A review. Anesthesiology. 1997;86(1):216–41. Review.
Ford DJ, Raj PP, Singh P, Regan KM, Ohlweiler D. Differential peripheral nerve block by local anesthetics in the cat. Anesthesiology. 1984;60(1):28–33. Comparative Study.
Molloy R, Candido K. Diagnostic nerve blocks. In: Benzon H, Raja SN, Molloy R, editors. Essentials of Pain Medicine and Regional Anesthesia. 2nd ed. Philadelphia: Elsevier; 2005. p. 181–9.
Rosenberg PH, Heinonen E, Jansson SE, Gripenberg J. Differential nerve block by bupivacaine and 2-chloroprocaine. An experimental study. Br J Anaesth. 1980;52(12):1183–9. Comparative Study In Vitro Research Support, Non-U.S. Gov’t.
Fink BR. Mechanisms of differential axial blockade in epidural and subarachnoid anesthesia. Anesthesiology. 1989;70(5):851–8. Research Support, U.S. Gov’t, P.H.S.
Cherry DA, Gourlay GK, McLachlan M, Cousins MJ. Diagnostic epidural opioid blockade and chronic pain: preliminary report. Pain. 1985;21(2):143–52. Case Reports.
Kappis M. Erfahungen mit localanasthesie bie bauchoperationen. Verh Dtsch Gesellsch Chir. 1914;43:97–9.
Eisenberg E, Carr DB, Chalmers TC. Neurolytic celiac plexus block for treatment of cancer pain: a meta-analysis. Anesth Analg. 1995;80(2):290–5. Meta-Analysis Research Support, U.S. Gov’t, P.H.S.
Brown DL. A retrospective analysis of neurolytic celiac plexus block for nonpancreatic intra-abdominal cancer pain. Reg Anesth. 1989;14(2):63–5. Research Support, Non-U.S. Gov’t.
Loukas M, Klaassen Z, Merbs W, Tubbs RS, Gielecki J, Zurada A. A review of the thoracic splanchnic nerves and celiac ganglia. Clin Anat. 2010;23(5):512–22. Review.
Ward EM, Rorie DK, Nauss LA, Bahn RC. The celiac ganglia in man: normal anatomic variations. Anesth Analg. 1979;58(6):461–5.
Zhang XM, Zhao QH, Zeng NL, Cai CP, Xie XG, Li CJ, et al. The celiac ganglia: anatomic study using MRI in cadavers. AJR Am J Roentgenol. 2006;186(6):1520–3. Research Support, Non-U.S. Gov’t.
de Leon-Casasola O. Neurolysis of the sympathetic axis for cancer pain management. In: Benzon H, Rathmell J, Wu C, Turk D, Argoff C, editors. Raj’s Practical Management of Pain. Philadelphia: Mosby Elsevier; 2008.
Molloy RE, Benzon HT. Neurolytic blocking agents: Uses and complications. In: Benzon H, Rathmell J, Wu C, Turk D, Argoff C, editors. Raj’s Practical Management of Pain. Philadelphia: Mosby Elsevier; 2008.
Fine PG, Bubela C. Chylothorax following celiac plexus block. Anesthesiology. 1985;63(4):454–6. Case Reports.
Leung JW, Bowen-Wright M, Aveling W, Shorvon PJ, Cotton PB. Coeliac plexus block for pain in pancreatic cancer and chronic pancreatitis. Br J Surg. 1983;70(12):730–2.
Ischia S, Ischia A, Polati E, Finco G. Three posterior percutaneous celiac plexus block techniques. A prospective, randomized study in 61 patients with pancreatic cancer pain. Anesthesiology. 1992;76(4):534–40. Clinical Trial Randomized Controlled Trial.
Turker G, Basagan-Mogol E, Gurbet A, Ozturk C, Uckunkaya N, Sahin S. A new technique for superior hypogastric plexus block: the posteromedian transdiscal approach. Tohoku J Exp Med. 2005;206(3):277–81. Case Reports.
Wechsler RJ, Maurer PM, Halpern EJ, Frank ED. Superior hypogastric plexus block for chronic pelvic pain in the presence of endometriosis: CT techniques and results. Radiology. 1995;196(1):103–6.
Chan WS, Peh WC, Ng KF, Tsui SL, Yang JC. Computed tomography scan-guided neurolytic superior hypogastric block complicated by somatic nerve damage in a severely kyphoscoliotic patient. Anesthesiology. 1997;86(6):1429–30. Case Reports Letter.
Plancarte R, Amescua C, Patt RB, Aldrete JA. Superior hypogastric plexus block for pelvic cancer pain. Anesthesiology. 1990;73(2):236–9.
Bajwa ZH, Ho C, Grush A, Kleefield J, Warfield CA. Discitis associated with pregnancy and spinal anesthesia. Anesthesia Analg. 2002;94(2):415–6. Case Reports, Table of contents.
Osti OL, Fraser RD, Vernon-Roberts B. Discitis after discography. The role of prophylactic antibiotics. J Bone Joint Surg Br. 1990;72(2):271–4. Research Support, Non-U.S. Gov’t.
Carragee EJ, Don AS, Hurwitz EL, Cuellar JM, Carrino JA, Herzog R. 2009 ISSLS Prize Winner: Does discography cause accelerated progression of degeneration changes in the lumbar disc: a ten-year matched cohort study. Spine (Phila Pa 1976). 2009;34(21):2338–45. Comparative Study.
Lin CS, Cheng JK, Hsu YW, Chen CC, Lao HC, Huang CJ, et al. Ultrasound-guided ganglion impar block: a technical report. Pain Med. 2010;11(3):390–4.
Waldman S. Hypogastric plexus block and impar ganglion block. Philadelphia: Saunders Elsevier; 2007.
Reig E, Abejon D, del Pozo C, Insausti J, Contreras R. Thermocoagulation of the ganglion impar or ganglion of Walther: description of a modified approach. Preliminary results in chronic, nononcological pain. Pain Pract. 2005;5(2):103–10.
Wemm Jr K, Saberski L. Modified approach to block the ganglion impar (ganglion of Walther). Reg Anesth. 1995;20(6):544–5. Letter.
Nebab EG, Florence IM. An alternative needle geometry for interruption of the ganglion impar. Anesthesiology. 1997;86(5):1213–4. Letter.
Datir A, Connell D. CT-guided injection for ganglion impar blockade: a radiological approach to the management of coccydynia. Clin Radiol. 2010;65(1):21–5. Evaluation Studies.
Munir MA, Zhang J, Ahmad M. A modified needle-inside-needle technique for the ganglion impar block. Can J Anaesth. 2004;51(9):915–7.
R P, R V, RB P. Neurolytic blocks of the sympathetic axis. RB P, editor. Philadelphia: Lippincott; 1993.
Toshniwal GR, Dureja GP, Prashanth SM. Transsacrococcygeal approach to ganglion impar block for management of chronic perineal pain: a prospective observational study. Pain physician. 2007;10(5):661–6. Clinical Trial.
Bhatnagar S, Khanna S, Roshni S, Goyal GN, Mishra S, Rana SP, et al. Early ultrasound-guided neurolysis for pain management in gastrointestinal and pelvic malignancies: an observational study in a tertiary care center of urban India. Pain Pract. 2011;12(1):23–32.
Cramer GD, Darby SA, editors. Basics and clinical anatomy of the spine, spinal cord, and ANS. St. Louis: Mosby-Year Book; 1995.
Loev MA, Varklet VL, Wilsey BL, Ferrante FM. Cryoablation: a novel approach to neurolysis of the ganglion impar. Anesthesiology. 1998;88(5):1391–3. Case Reports.
Karmakar MK, Ho AM, Law BK, Wong AS, Shafer SL, Gin T. Arterial and venous pharmacokinetics of ropivacaine with and without epinephrine after thoracic paravertebral block. Anesthesiology. 2005;103(4):704–11. Randomized Controlled Trial.
Doi K, Nikai T, Sakura S, Saito Y. Intercostal nerve block with 5% tetracaine for chronic pain syndromes. J Clin Anesth. 2002;14(1):39–41.
Shir Y, Shapira S, Magora F. Continuous intercostal nerve block for chronic pain. Harefuah. 1989;116(9):461–3.
Benzon HT, Raj PP. Raj’s practical management of pain. 4th ed. Philadelphia: Mosby-Elsevier; 2008.
Shanti CM, Carlin AM, Tyburski JG. Incidence of pneumothorax from intercostal nerve block for analgesia in rib fractures. J Trauma. 2001;51(3):536–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer Science+Business Media New York
About this chapter
Cite this chapter
Veizi, I.E., Wynne, M., Hayek, S.M. (2015). Establishing Diagnosis of Chronic Abdominal Pain: Pain Medicine view. In: Kapural, L. (eds) Chronic Abdominal Pain. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1992-5_4
Download citation
DOI: https://doi.org/10.1007/978-1-4939-1992-5_4
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4939-1991-8
Online ISBN: 978-1-4939-1992-5
eBook Packages: MedicineMedicine (R0)