Skip to main content

Establishing Diagnosis of Chronic Abdominal Pain: Pain Medicine view

  • Chapter
  • First Online:

Abstract

Chronic abdominal pain (CAP) is a complex disorder whose optimal treatment requires an interdisciplinary team encompassing medical, interventional/surgical, and psychotherapy approaches. Current understanding of the neurophysiological, neuroanatomical, and behavioral components of CAP is still incomplete. The central focus of a successful treatment in CAP is the initial correct diagnosis of the predominant pain pathway/source. From the Pain Medicine perspective, besides a careful clinical impression and laboratory and radiological studies, it involves employing the utility of neural blocks as a diagnostic as well as a prognostic tool for subsequent neuro ablative or neuromodulatory procedures. The poorly delineated pathophysiology and variable clinical course/heterogeneity of CAP suggests that individualized strategies are required for optimal management. This overview presents a brief review of the nature and pathophysiology of CAP as well as various diagnostic approaches that have been found to be effective in Pain Medicine for treatment of CAP.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Houghton AK, Wang CC, Westlund KN. Do nociceptive signals from the pancreas travel in the dorsal column? Pain. 2001;89(2–3):207–20. Research Support, U.S. Gov’t, P.H.S.

    Article  CAS  PubMed  Google Scholar 

  2. Djouhri L, Lawson SN. Abeta-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals. Brain Res Brain Res Rev. 2004;46(2):131–45. Comparative Study Research Support, Non-U.S. Gov’t Review.

    Article  PubMed  Google Scholar 

  3. Djouhri L, Lawson SN. Differences in the size of the somatic action potential overshoot between nociceptive and non-nociceptive dorsal root ganglion neurones in the guinea-pig. Neuroscience. 2001;108(3):479–91. Research Support, Non-U.S. Gov’t.

    Article  CAS  PubMed  Google Scholar 

  4. Lawson SN. Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres. Exp Physiol. 2002;87(2):239–44. Research Support, Non-U.S. Gov’t Review.

    Article  CAS  PubMed  Google Scholar 

  5. Winnie A, Candido K. Differential neural blockade for the diagnosis of pain. In: Waldman S, editor. Pain management. Philadelphia: Saunders; 2007. p. 155–66.

    Chapter  Google Scholar 

  6. Hogan QH, Abram SE. Neural blockade for diagnosis and prognosis. A review. Anesthesiology. 1997;86(1):216–41. Review.

    Article  CAS  PubMed  Google Scholar 

  7. Ford DJ, Raj PP, Singh P, Regan KM, Ohlweiler D. Differential peripheral nerve block by local anesthetics in the cat. Anesthesiology. 1984;60(1):28–33. Comparative Study.

    Article  CAS  PubMed  Google Scholar 

  8. Molloy R, Candido K. Diagnostic nerve blocks. In: Benzon H, Raja SN, Molloy R, editors. Essentials of Pain Medicine and Regional Anesthesia. 2nd ed. Philadelphia: Elsevier; 2005. p. 181–9.

    Chapter  Google Scholar 

  9. Rosenberg PH, Heinonen E, Jansson SE, Gripenberg J. Differential nerve block by bupivacaine and 2-chloroprocaine. An experimental study. Br J Anaesth. 1980;52(12):1183–9. Comparative Study In Vitro Research Support, Non-U.S. Gov’t.

    Article  CAS  PubMed  Google Scholar 

  10. Fink BR. Mechanisms of differential axial blockade in epidural and subarachnoid anesthesia. Anesthesiology. 1989;70(5):851–8. Research Support, U.S. Gov’t, P.H.S.

    Article  CAS  PubMed  Google Scholar 

  11. Cherry DA, Gourlay GK, McLachlan M, Cousins MJ. Diagnostic epidural opioid blockade and chronic pain: preliminary report. Pain. 1985;21(2):143–52. Case Reports.

    Article  CAS  PubMed  Google Scholar 

  12. Kappis M. Erfahungen mit localanasthesie bie bauchoperationen. Verh Dtsch Gesellsch Chir. 1914;43:97–9.

    Google Scholar 

  13. Eisenberg E, Carr DB, Chalmers TC. Neurolytic celiac plexus block for treatment of cancer pain: a meta-analysis. Anesth Analg. 1995;80(2):290–5. Meta-Analysis Research Support, U.S. Gov’t, P.H.S.

    CAS  PubMed  Google Scholar 

  14. Brown DL. A retrospective analysis of neurolytic celiac plexus block for nonpancreatic intra-abdominal cancer pain. Reg Anesth. 1989;14(2):63–5. Research Support, Non-U.S. Gov’t.

    CAS  PubMed  Google Scholar 

  15. Loukas M, Klaassen Z, Merbs W, Tubbs RS, Gielecki J, Zurada A. A review of the thoracic splanchnic nerves and celiac ganglia. Clin Anat. 2010;23(5):512–22. Review.

    Article  PubMed  Google Scholar 

  16. Ward EM, Rorie DK, Nauss LA, Bahn RC. The celiac ganglia in man: normal anatomic variations. Anesth Analg. 1979;58(6):461–5.

    Article  CAS  PubMed  Google Scholar 

  17. Zhang XM, Zhao QH, Zeng NL, Cai CP, Xie XG, Li CJ, et al. The celiac ganglia: anatomic study using MRI in cadavers. AJR Am J Roentgenol. 2006;186(6):1520–3. Research Support, Non-U.S. Gov’t.

    Article  PubMed  Google Scholar 

  18. de Leon-Casasola O. Neurolysis of the sympathetic axis for cancer pain management. In: Benzon H, Rathmell J, Wu C, Turk D, Argoff C, editors. Raj’s Practical Management of Pain. Philadelphia: Mosby Elsevier; 2008.

    Google Scholar 

  19. Molloy RE, Benzon HT. Neurolytic blocking agents: Uses and complications. In: Benzon H, Rathmell J, Wu C, Turk D, Argoff C, editors. Raj’s Practical Management of Pain. Philadelphia: Mosby Elsevier; 2008.

    Google Scholar 

  20. Fine PG, Bubela C. Chylothorax following celiac plexus block. Anesthesiology. 1985;63(4):454–6. Case Reports.

    Article  CAS  PubMed  Google Scholar 

  21. Leung JW, Bowen-Wright M, Aveling W, Shorvon PJ, Cotton PB. Coeliac plexus block for pain in pancreatic cancer and chronic pancreatitis. Br J Surg. 1983;70(12):730–2.

    Article  CAS  PubMed  Google Scholar 

  22. Ischia S, Ischia A, Polati E, Finco G. Three posterior percutaneous celiac plexus block techniques. A prospective, randomized study in 61 patients with pancreatic cancer pain. Anesthesiology. 1992;76(4):534–40. Clinical Trial Randomized Controlled Trial.

    Article  CAS  PubMed  Google Scholar 

  23. Turker G, Basagan-Mogol E, Gurbet A, Ozturk C, Uckunkaya N, Sahin S. A new technique for superior hypogastric plexus block: the posteromedian transdiscal approach. Tohoku J Exp Med. 2005;206(3):277–81. Case Reports.

    Article  PubMed  Google Scholar 

  24. Wechsler RJ, Maurer PM, Halpern EJ, Frank ED. Superior hypogastric plexus block for chronic pelvic pain in the presence of endometriosis: CT techniques and results. Radiology. 1995;196(1):103–6.

    Article  CAS  PubMed  Google Scholar 

  25. Chan WS, Peh WC, Ng KF, Tsui SL, Yang JC. Computed tomography scan-guided neurolytic superior hypogastric block complicated by somatic nerve damage in a severely kyphoscoliotic patient. Anesthesiology. 1997;86(6):1429–30. Case Reports Letter.

    Article  CAS  PubMed  Google Scholar 

  26. Plancarte R, Amescua C, Patt RB, Aldrete JA. Superior hypogastric plexus block for pelvic cancer pain. Anesthesiology. 1990;73(2):236–9.

    Article  CAS  PubMed  Google Scholar 

  27. Bajwa ZH, Ho C, Grush A, Kleefield J, Warfield CA. Discitis associated with pregnancy and spinal anesthesia. Anesthesia Analg. 2002;94(2):415–6. Case Reports, Table of contents.

    Google Scholar 

  28. Osti OL, Fraser RD, Vernon-Roberts B. Discitis after discography. The role of prophylactic antibiotics. J Bone Joint Surg Br. 1990;72(2):271–4. Research Support, Non-U.S. Gov’t.

    CAS  PubMed  Google Scholar 

  29. Carragee EJ, Don AS, Hurwitz EL, Cuellar JM, Carrino JA, Herzog R. 2009 ISSLS Prize Winner: Does discography cause accelerated progression of degeneration changes in the lumbar disc: a ten-year matched cohort study. Spine (Phila Pa 1976). 2009;34(21):2338–45. Comparative Study.

    Article  Google Scholar 

  30. Lin CS, Cheng JK, Hsu YW, Chen CC, Lao HC, Huang CJ, et al. Ultrasound-guided ganglion impar block: a technical report. Pain Med. 2010;11(3):390–4.

    Article  PubMed  Google Scholar 

  31. Waldman S. Hypogastric plexus block and impar ganglion block. Philadelphia: Saunders Elsevier; 2007.

    Google Scholar 

  32. Reig E, Abejon D, del Pozo C, Insausti J, Contreras R. Thermocoagulation of the ganglion impar or ganglion of Walther: description of a modified approach. Preliminary results in chronic, nononcological pain. Pain Pract. 2005;5(2):103–10.

    Article  PubMed  Google Scholar 

  33. Wemm Jr K, Saberski L. Modified approach to block the ganglion impar (ganglion of Walther). Reg Anesth. 1995;20(6):544–5. Letter.

    PubMed  Google Scholar 

  34. Nebab EG, Florence IM. An alternative needle geometry for interruption of the ganglion impar. Anesthesiology. 1997;86(5):1213–4. Letter.

    Article  CAS  PubMed  Google Scholar 

  35. Datir A, Connell D. CT-guided injection for ganglion impar blockade: a radiological approach to the management of coccydynia. Clin Radiol. 2010;65(1):21–5. Evaluation Studies.

    Article  CAS  PubMed  Google Scholar 

  36. Munir MA, Zhang J, Ahmad M. A modified needle-inside-needle technique for the ganglion impar block. Can J Anaesth. 2004;51(9):915–7.

    Article  PubMed  Google Scholar 

  37. R P, R V, RB P. Neurolytic blocks of the sympathetic axis. RB P, editor. Philadelphia: Lippincott; 1993.

    Google Scholar 

  38. Toshniwal GR, Dureja GP, Prashanth SM. Transsacrococcygeal approach to ganglion impar block for management of chronic perineal pain: a prospective observational study. Pain physician. 2007;10(5):661–6. Clinical Trial.

    PubMed  Google Scholar 

  39. Bhatnagar S, Khanna S, Roshni S, Goyal GN, Mishra S, Rana SP, et al. Early ultrasound-guided neurolysis for pain management in gastrointestinal and pelvic malignancies: an observational study in a tertiary care center of urban India. Pain Pract. 2011;12(1):23–32.

    Article  PubMed  Google Scholar 

  40. Cramer GD, Darby SA, editors. Basics and clinical anatomy of the spine, spinal cord, and ANS. St. Louis: Mosby-Year Book; 1995.

    Google Scholar 

  41. Loev MA, Varklet VL, Wilsey BL, Ferrante FM. Cryoablation: a novel approach to neurolysis of the ganglion impar. Anesthesiology. 1998;88(5):1391–3. Case Reports.

    Article  CAS  PubMed  Google Scholar 

  42. Karmakar MK, Ho AM, Law BK, Wong AS, Shafer SL, Gin T. Arterial and venous pharmacokinetics of ropivacaine with and without epinephrine after thoracic paravertebral block. Anesthesiology. 2005;103(4):704–11. Randomized Controlled Trial.

    Article  CAS  PubMed  Google Scholar 

  43. Doi K, Nikai T, Sakura S, Saito Y. Intercostal nerve block with 5% tetracaine for chronic pain syndromes. J Clin Anesth. 2002;14(1):39–41.

    Article  CAS  PubMed  Google Scholar 

  44. Shir Y, Shapira S, Magora F. Continuous intercostal nerve block for chronic pain. Harefuah. 1989;116(9):461–3.

    CAS  PubMed  Google Scholar 

  45. Benzon HT, Raj PP. Raj’s practical management of pain. 4th ed. Philadelphia: Mosby-Elsevier; 2008.

    Google Scholar 

  46. Shanti CM, Carlin AM, Tyburski JG. Incidence of pneumothorax from intercostal nerve block for analgesia in rib fractures. J Trauma. 2001;51(3):536–9.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Salim M. Hayek M.D., Ph.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Veizi, I.E., Wynne, M., Hayek, S.M. (2015). Establishing Diagnosis of Chronic Abdominal Pain: Pain Medicine view. In: Kapural, L. (eds) Chronic Abdominal Pain. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1992-5_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1992-5_4

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1991-8

  • Online ISBN: 978-1-4939-1992-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics