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Silicon Probe Techniques for Large-Scale Multiunit Recording

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Analysis and Modeling of Coordinated Multi-neuronal Activity

Part of the book series: Springer Series in Computational Neuroscience ((NEUROSCI,volume 12))

Abstract

Chapter 1 laid the groundwork for extracellular electrophysiology and the history of microelectrode and microdrive development. However, one of the most technically advanced areas of electrode fabrication is found in the microprobe (e.g., silicon probes) industry where nanoscale fabrication techniques are used to increase recorded neuron yield. To date, these probes have the highest number of contacts per probe and can be combined with integrated circuits, optogenetic control, and drug delivery. This chapter will review a history of development in this field, emphasizing technical advances and what it means for the investigation of neurons.

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Acknowledgments

Special thanks to Mary Steenland, Erik Hopkins, and Dr. Masami Tatsuno for a careful editing of this chapter.

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Authors and Affiliations

  1. Department of Neuroscience, University of Lethbridge, 440l University Drive W, Lethbridge, AB, Canada, TlK3M4

    Hendrik W. Steenland Ph.D. & Bruce L. McNaughton Ph.D.

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  1. Hendrik W. Steenland Ph.D.
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  2. Bruce L. McNaughton Ph.D.
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Corresponding author

Correspondence to Bruce L. McNaughton Ph.D. .

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Editors and Affiliations

  1. The University of Lethbridge, Lethbridge, Alberta, Canada

    Masami Tatsuno

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Steenland, H.W., McNaughton, B.L. (2015). Silicon Probe Techniques for Large-Scale Multiunit Recording. In: Tatsuno, M. (eds) Analysis and Modeling of Coordinated Multi-neuronal Activity. Springer Series in Computational Neuroscience, vol 12. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1969-7_2

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