Abstract
Substance use is often associated with motor vehicle accidents, falls, drownings, thermal injuries, homicide, and suicide. In the United States half of the trauma beds are occupied by patients involved in alcohol-related traffic accidents. Cocaine and cannabis use place the patient at a higher risk of all types of injuries. Patients who stay in the ICU may develop withdrawal syndromes; these are physiologic responses to abrupt withdrawal or reduction of drug use and complicate the management of these patients.
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References
Hoffmann JR, Schriger DL, Luo JS. The empiric use of naloxone in patients with altered mental status: a reappraisal. Ann Emerg Med. 1991;20:246–52.
Nelsen J, Marraffa J, Jones L, Grant W. Management considerations follow overdoses of modified-release morphine preparations. World J Emerg Med. 2010;1:75–6.
Jaffe JH. Drug addiction and drug abuse. In: Gilman AG, Rall TW, Nies AS, et al., editors. Goodman and Gilman’s the pharmacological basis of therapeutics. 8th ed. New York: Pergamon Press; 1990. p. 522–73.
O’Connor PG, Kosten TR, Stine SM. Management of opioid intoxication and withdrawal. In: Graham AW, Schultz TK, Mayo-Smith MF, et al., editors. Principles of addiction medicine. 3rd ed. Chevy Chase: American Society of Addiction Medicine; 2003. p. 651–68.
American Psychiatric Association. Practice guideline for the treatment of patients with substance use disorders. 2nd ed. Washington, DC: American Psychiatric Association; 2006.
Fiellin DA, O’Connor PG. Office-based treatment of opioid-dependent patients. New Engl J Med. 2002;347(11):817–23.
Gouldin WM, Kennedy DT, Small RE. Methadone: history and recommendations for use in analgesia. Am Pain Soc Bull. 2000;10(5):1–11.
Fiellin DA, O’Connor PG. New federal initiatives to enhance the medical treatment of opioid dependence. Ann Intern Med. 2002;137(8):688–92.
Loimer N, Schmid R, Presslich O, et al. Naloxone treatment for opiate withdrawal syndrome. Br J Psychiatry. 1988;153:851–2.
Amass L, Ling W, Freese TE, et al. Bringing buprenorphine–naloxone detoxification to community treatment providers: the NIDA clinical trials network field experience. Am J Addict. 2004;13 Suppl 1:S42–66.
http://reference.medscape.com/drug/romazicon-flumazenil-343731
Kosten TR, O’Connor PG. Management of drug and alcohol withdrawal. N Engl J Med. 2003;348(18):1786–95.
Mas-Morey P, Visser MHM, Winkelmolen L, et al. Clinical toxicology and management of intoxications with synthetic cathinones (“Bath Salts”). J Pharm Pract. 2013;26(4):353–7. doi:10.1177/0897190012465949.
Carhart-Harris RL, et al. A web-based survey on mephedrone. Drug Alcohol Depend. 2011;118(1):19–22. doi:10.1016/j.drugalcdep.2011.02.011.
Nelson L, Lewin N, Howland MR, Hoffman R, Goldfrank L, Flomenbaum N, editors. Goldfrank’s toxicologic emergencies. 9th ed. New York: McGraw-Hill Professional; 2010.
http://www.erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_dose.shtml
Awissi D, Lebrun G, Coursin DB, Riker RR, Skrobik Y. Alcohol withdrawal and delirium tremens in the critically ill: a systemic review and commentary. Intensive Care Med. 2013;39(1):16–30. doi:10.1007/s00134-012-2758-y [Epub 27 Nov 2012].
Carlson RW, Kumar NN, Wong-Mckinstry E, et al. Alcohol withdrawal syndrome. Crit Care Clin. 2012;28(4):549–85. doi:10.1016/j.ccc.2012.07.004. Review.
Al-Sanouri I, Dikin M, Soubani AO. Critical care aspects of alcohol abuse. South Med J. 2005;98(3):372–81.
Tetrault, J, O’Connor PG. Substance abuse and withdrawal in the critical care setting. Crit Care Clin. 2008;24(4):767–88, viii. doi:10.1016/j.ccc.2008.05.005
Corfee F. Alcohol withdrawal in the critical care unit. Aust Crit Care. 2011;24(2):110–6. doi:10.1016/j.aucc.2010.08.005 [Epub 25 Sep 2010].
Jenkins DH. Substance abuse and withdrawal in the intensive care unit. Surg Clin North Am. 2000;80(3):1033–53.
Sarff M, Gold JA. Alcohol withdrawal syndromes in the intensive care unit. Crit Care Med. 2010;38(9 Suppl):S494–501. doi:10.1097/CCM.0b013e3181ec5412.
Honisett TD. Nicotine replacement therapy for smokers admitted to intensive care. Intensive Crit Care Nurs. 2001;17(6):318–21.
Lucidarme O, Seguin A, Daubin C, et al. Nicotine withdrawal and agitation in ventilated critically ill patients. Crit Care. 2010;14(2):R58. doi:10.1186/cc8954 [Epub 9 Apr 2010].
Padula C, Willey C. Tobacco withdrawal in CCU patients. Dimens Crit Care Nurs. 1993;12(6):305–12.
Shiffman S, Waters A, Hickcox M. The nicotine dependence syndrome scale: a multidimensional measure of nicotine dependence. Nicotine Tob Res. 2004;6(2):327–48.
Wong G, Irwin MG. Poisoning with ilicit substances: toxicology for the anaesthetist. Anaesthesia. 2013;68 Suppl 1:117–24. doi:10.1111/anae.12053.
Chang W. Amphetamines. In: Nelson L, Lewin N, Howland MR, Hoffman R, Goldfrank L, Flomenbaum N, editors. Goldfrank’s toxicologic emergencies. 9th ed. New York: McGraw-Hill Professional; 2010.
Gawin F, Ellinwood Jr EH. Cocaine and other stimulants. N Engl J Med. 1988;318(18):1173–82.
Shoptaw SJ, Kao U, Heinzerling K, Ling W. Treatment for amphetamine withdrawal (review). Cochrane Database Syst Rev. 2009;2:CD003021. doi:10.1002/14651858.CD003021.pub2.
Hoskins MH, Leleiko RM, Ramos JJ, Sola S, Caneer PM, Khan BV. Effects of labetalol on hemodynamic parameters and soluble biomarkers of inflammation in acute coronary syndrome in patients with active cocaine use. J Cardiovasc Pharmacol Ther. 2010;15(1):47–52. doi:10.1177/1074248409358409.
Damodaran S. Cocaine and beta-blockers: the paradigm. Eur J Intern Med. 2010;21(2):84–6. doi:10.1016/j.ejim.2009.11.010 [Epub 16 Dec 2009].
Friedmann PD. Alcohol use in adults. N Engl J Med. 2013;368(17):1655–6. doi:10.1056/NEJMc1302445.
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Deshpande, R., Gong, J., Chadha, R., Haddadin, A. (2015). Management of the Drug Abusing Patient in the ICU. In: Kaye, A., Vadivelu, N., Urman, R. (eds) Substance Abuse. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1951-2_31
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DOI: https://doi.org/10.1007/978-1-4939-1951-2_31
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