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Arteriovenous Malformations of the Brain

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Neurointervention in the Medical Specialties

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Arteriovenous malformations (AVM) of the brain (also known as pial or parenchymal AVMs) are defined as intracranial space-occupying lesions composed of feeding arteries, draining veins, and a nidus of tangled vessels without an intervening capillary bed. There is no normal interposed brain tissue, but there can be surrounding gliosis. Morphology can vary, but AVMs are typically triangular in shape with the base towards the cortex and the apex towards the ventricular system [Brown et al. Mayo Clin Proc 80(2):269–81, 2005; Winn. Youmans neurological surgery. 6th edn. Elsevier, Philadelphia, PA, 2011; Moftakhar et al. Neurosurg Focus 26(5):E10, 2009]. While much of the pathophysiology, epidemiology, and natural history remain unclear, there has been successful advancement in the understanding and management of these complex lesions, especially with regard to the application of microsurgical, radiosurgical, and endovascular therapies.

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Authors and Affiliations

  1. Department of Neurology and Ophthamology, Michigan State University, B401 MSU Clinical Center, 804 Service Road, East Lansing, MI, 48824, USA

    Anmar Razak M.D. & Syed I. Hussain M.D.

  2. Department of Neurosurgery, Saint Louis University, 3635 Vista Avenue, St. Louis, MO, 63104, USA

    Joanna Kemp M.D. & Jeroen R. Coppens M.D.

Authors
  1. Anmar Razak M.D.
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  2. Syed I. Hussain M.D.
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  3. Joanna Kemp M.D.
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  4. Jeroen R. Coppens M.D.
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Correspondence to Jeroen R. Coppens M.D. .

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Editors and Affiliations

  1. Department of Neurology and Psychiatry, Saint Louis University, St. Louis, Missouri, USA

    Randall C. Edgell

  2. Department of Neurology, University of Texas Health Science Center, UT-HEALTH, Houston, Texas, USA

    Sean I. Savitz

  3. Department of Neurosurgery, Albany Medical Center, Albany, New York, USA

    John Dalfino

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Razak, A., Hussain, S.I., Kemp, J., Coppens, J.R. (2015). Arteriovenous Malformations of the Brain. In: Edgell, R., Savitz, S., Dalfino, J. (eds) Neurointervention in the Medical Specialties. Current Clinical Neurology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1942-0_12

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