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Protection by Glutamine After Ischemia/Reperfusion Injury

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Glutamine in Clinical Nutrition

Part of the book series: Nutrition and Health ((NH))

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Abstract

Ischemia/reperfusion (I/R) occurs in a wide range of clinical scenarios including trauma, shock, transplantation, stroke, myocardial infarction, coronary angioplasty, thrombolytic therapy, coronary revascularization, and autoimmune diseases. Ischemia can cause tissue and organ damage due to an insufficient oxygen and glucose, which are necessary for cellular metabolism, which subsequently results in tissue or organ dysfunction. Although reperfusion is necessary to attenuate injury of ischemic tissues, it can trigger a cascade of events leading to additional tissue injury and even remote organ injury. Therefore, I/R injury contributes to the pathophysiology of a wide range of clinical diseases and is associated with considerable morbidity and mortality.

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Authors and Affiliations

  1. Department of Surgery, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX, 77030, USA

    Kechen Ban Ph.D. & Rosemary A. Kozar M.D., Ph.D.

Authors
  1. Kechen Ban Ph.D.
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  2. Rosemary A. Kozar M.D., Ph.D.
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Corresponding author

Correspondence to Kechen Ban Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Intensive Care, Barnet and Chase Farm Hospitals, London, United Kingdom

    Rajkumar Rajendram

  2. Department of Nutrition and Dietetics, Diabetes and Nutritional Sciences, School of Medicine, King’s College London, London, United Kingdom

    Victor R. Preedy

  3. Department of Biomedical Sciences, University of Westminster, London, United Kingdom

    Vinood B. Patel

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Ban, K., Kozar, R.A. (2015). Protection by Glutamine After Ischemia/Reperfusion Injury. In: Rajendram, R., Preedy, V., Patel, V. (eds) Glutamine in Clinical Nutrition. Nutrition and Health. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1932-1_35

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  • DOI: https://doi.org/10.1007/978-1-4939-1932-1_35

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1931-4

  • Online ISBN: 978-1-4939-1932-1

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