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Glutamine Supplementation in Multiple Trauma Patients

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Glutamine in Clinical Nutrition

Part of the book series: Nutrition and Health ((NH))

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Abstract

During stress conditions such as multiple trauma and critical illness, the demand for glutamine increases and its concentration in plasma and muscle falls dramatically. Therefore, glutamine has been re-classified as an essential amino acid under such catabolic conditions. The role of glutamine supplementation in trauma patients has been extensively studies. Despite the numerous clinical trials that investigated the effect of enteral and parenteral glutamine supplementation in multiple trauma patients, the results are inconclusive. Glutamine supplementation through parenteral route has been associated with reduced infectious complications, mortality, costs and hospital length of stay. However, glutamine supplementation in multiple trauma patients receiving enteral nutrition and its best route are still controversial. Although glutamine supplementation is recommended in multiple trauma patients, large well designed multi-centre trials are required to provide a confirmed conclusion.

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Authors and Affiliations

  1. Health and Nutrition Department, College of Food and Agriculture, United Arab Emirates University, 15551, Al Ain, United Arab Emirates

    Ruqaiya M. Al Balushi B.Sc., M.Sc., Ph.D.

  2. Department of Intensive Care Medicine, Royal Brisbane & Women’s Hospital, Brisbane, QLD, Australia

    Jennifer D. Paratz M.Phty., Ph.D., F.A.C.P. & Jeremy Cohen M.R.C.P., F.R.C.A., Ph.D.

  3. Trauma & Critical Care Research Centre, The University of Queensland, School of Medicine, Burns, Brisbane, QLD, Australia

    Jennifer D. Paratz M.Phty., Ph.D., F.A.C.P. & Jeremy Cohen M.R.C.P., F.R.C.A., Ph.D.

  4. Department of Nutrition and Dietetics, Royal Brisbane & Women’s Hospital, Brisbane, QLD, Australia

    Merrilyn Banks B.Sc., M. Hlth. Sc., Ph.D.

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  1. Ruqaiya M. Al Balushi B.Sc., M.Sc., Ph.D.
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  2. Jennifer D. Paratz M.Phty., Ph.D., F.A.C.P.
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  3. Jeremy Cohen M.R.C.P., F.R.C.A., Ph.D.
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  4. Merrilyn Banks B.Sc., M. Hlth. Sc., Ph.D.
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Correspondence to Ruqaiya M. Al Balushi B.Sc., M.Sc., Ph.D. .

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Editors and Affiliations

  1. Department of Intensive Care, Barnet and Chase Farm Hospitals, London, United Kingdom

    Rajkumar Rajendram

  2. Department of Nutrition and Dietetics, Diabetes and Nutritional Sciences, School of Medicine, King’s College London, London, United Kingdom

    Victor R. Preedy

  3. Department of Biomedical Sciences, University of Westminster, London, United Kingdom

    Vinood B. Patel

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Al Balushi, R.M., Paratz, J.D., Cohen, J., Banks, M. (2015). Glutamine Supplementation in Multiple Trauma Patients. In: Rajendram, R., Preedy, V., Patel, V. (eds) Glutamine in Clinical Nutrition. Nutrition and Health. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1932-1_14

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  • DOI: https://doi.org/10.1007/978-1-4939-1932-1_14

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