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Handbook of Clinical Nutrition and Aging pp 215–236Cite as

Chronic Heart Failure

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Part of the book series: Nutrition and Health ((NH))

Abstract

Age-related changes in the cardiovascular system coupled with the increasing prevalence of cardiovascular disorders with advancing age, especially hypertension, coronary artery disease, and valvular heart disease, lead to a progressive rise in the prevalence of heart failure with increasing age. Nutritional factors may contribute to the development of heart failure and, conversely, heart failure may lead to nutritional deficiencies. Dietary factors also play a key role in heart failure management. This chapter provides an overview of the clinical features of heart failure and reviews the interactions between heart failure, nutrition, and aging. The chapter concludes with a summary of nutritional recommendations for management of older patients with heart failure.

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References

  1. Katz AM, Katz PB. Diseases of the heart in the work of Hippocrates. Br Heart J. 1961;24:257–64.

    Article  Google Scholar 

  2. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics—2012 update: a report from the American Heart Association. Circulation. 2012;125(1):e2–220.

    Article  PubMed  Google Scholar 

  3. Kannel WB. Incidence and epidemiology of heart failure. Heart Fail Rev. 2000;5(2):167–73.

    Article  CAS  PubMed  Google Scholar 

  4. DeFrances CJ, Podgornik MN. 2004 National hospital discharge survey. Adv Data. 2006;371:1–19.

    PubMed  Google Scholar 

  5. Kozak LJ, DeFrances CJ, Hall MJ. National hospital discharge survey: 2004 annual summary with detailed diagnosis and procedure data. Vital Health Stat 13. 2006;(162):1–209.

    Google Scholar 

  6. Lee WC, Chavez YE, Baker T, Luce BR. Economic burden of heart failure: a summary of recent literature. Heart Lung. 2004;33(6):362–71.

    Article  PubMed  Google Scholar 

  7. Heidenreich PA, Trogdon JG, Khavjou OA, Butler J, Dracup K, Ezekowitz MD, et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation. 2011;123(8):933–44.

    Article  PubMed  Google Scholar 

  8. Gottdiener JS, Arnold AM, Aurigemma GP, Polak JF, Tracy RP, Kitzman DW, et al. Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study. J Am Coll Cardiol. 2000;35(6):1628–37.

    Article  CAS  PubMed  Google Scholar 

  9. Levy D, Larson MG, Vasan RS, Kannel WB, Ho kalon KL. [The progression from hypertension to congestive heart failure]. JAMA. 1996;275(20):1557–62.

    Article  CAS  PubMed  Google Scholar 

  10. Kapila R, Mahajan RP. Diastolic dysfunction. Continuing education in anaesthesia. Crit Care Pain. 2009;9(1):29–33.

    Google Scholar 

  11. Vasan RS, Larson MG, Benjamin EJ, Evans JC, Reiss CK, Levy D. Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohort. J Am Coll Cardiol. 1999;33(7):1948–55.

    Article  CAS  PubMed  Google Scholar 

  12. Kitzman DW, Gardin JM, Gottdiener JS, Arnold A, Boineau R, Aurigemma G, et al. Importance of heart failure with preserved systolic function in patients ≥65 years of age. Am J Cardiol. 2001;87(4):413–9.

    Article  CAS  PubMed  Google Scholar 

  13. Croft JB, Giles WH, Pollard RA, Keenan NL, Casper ML, Anda RF. Heart failure survival among older adults in the United States. Arch Intern Med. 1999;159(5):505–10.

    Article  CAS  PubMed  Google Scholar 

  14. Mozaffarian D, Anker SD, Anand I, Linker DT, Sullivan MD, Cleland JG, et al. Prediction of mode of death in heart failure: the Seattle Heart Failure Model. Circulation. 2007;116(4):392–8.

    Article  PubMed  Google Scholar 

  15. Benbarkat H, Addetia K, Eisenberg MJ, Sheppard R, Filion KB, Michel C. Application of the Seattle Heart Failure Model in Patients >80 years of age enrolled in a tertiary care heart failure clinic. Am J Cardiol. 2012;110(11):1663–6.

    Article  PubMed  Google Scholar 

  16. Vinson JM, Rich MW, Sperry JC, Shah AS, McNamara T. Early readmission of elderly patients with congestive heart failure. J Am Geriatr Soc. 1991;39(10):1290–5.

    Google Scholar 

  17. Krumholz HM, Parent EM, Tu N, Vaccarino V, Wang Y, Radford MJ, et al. Readmission after hospitalization for congestive heart failure among medicare benificiaries. Arch Intern Med. 1997;157:99–104.

    Article  CAS  PubMed  Google Scholar 

  18. Ho KK, Anderson KM, Kannel WB, Grossman W, Levy D. Survival after the onset of congestive heart failure in Framingham Heart Study subjects. Circulation. 1993;88(1):107–15.

    Article  CAS  PubMed  Google Scholar 

  19. Pernenkil R, Vinson JM, Shaha S, Beckham V, Wittenberg C, Rich MW. Course and prognosis in patients > or =70 years of age with congestive heart failure and normal versus abnormal left ventricular ejection fraction. Am J Cardiol. 1997;79(2):216–9.

    Article  CAS  PubMed  Google Scholar 

  20. Senni M, Tribouilloy CM, Rodeheffer RJ, Jacobsen SJ, Evans JM, Bailey KR, et al. Congestive heart failure in the community: a study of all incident cases in Olmsted county, Minnesota, in 1991. Circulation. 1998;98(21):2282–9.

    Article  CAS  PubMed  Google Scholar 

  21. Chinnaiyan KM, Alexander D, Maddens M, McCullough PA. Curriculum in cardiology: integrated diagnosis and management of diastolic heart failure. Am Heart J. 2007;153(2):189–200.

    Article  PubMed  Google Scholar 

  22. Zile MR, Gaasch WH, Anand IS, Haass M, Little WC, Miller AB, et al. Mode of death in patients with heart failure and a preserved ejection fraction: results from the Irbesartan in Heart Failure with Preserved Ejection Fraction Study (I-Preserve) trial. Circulation. 2010;121(12):1393–405.

    Article  PubMed  Google Scholar 

  23. Heart Failure Society of America. HFSA 2010 comprehensive heart failure practice guideline. J Card Fail. 2010;16(6):e1–192.

    Article  Google Scholar 

  24. Rich MW, Beckham V, Wittenberg C, Leven CL, Freedland KE, Carney RM. A multidisciplinary intervention to prevent the readmission of elderly patients with congestive heart failure. N Engl J Med. 1995;333(18):1190–5.

    Article  CAS  PubMed  Google Scholar 

  25. McAlister FA, Lawson FM, Teo KK, Armstrong PW. A systematic review of randomized trials of disease management programs in heart failure. Am J Med. 2001;110(5):378–84.

    Article  CAS  PubMed  Google Scholar 

  26. Flather MD, Yusuf S, Køber L, Pfeffer M, Hall A, Murray G, et al. Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. Lancet. 2000;355(9215):1575–81.

    Article  CAS  PubMed  Google Scholar 

  27. Pitt B, Poole-Wilson PA, Segal R, Martinez FA, Dickstein K, Camm AJ, et al. Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial—the Losartan Heart Failure Survival Study ELITE II. Lancet. 2000;355(9215):1582–7.

    Article  CAS  PubMed  Google Scholar 

  28. Cohn JN, Archibald DG, Ziesche S, Franciosa JA, Harston WE, Tristani FE, et al. Effect of vasodilator therapy on mortality in chronic congestive heart failure. N Engl J Med. 1986;314(24):1547–52.

    Article  CAS  PubMed  Google Scholar 

  29. Cohn J, Johnson G, Ziesche S. A comparison of enalapril with hydralazine–isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med. 1991;325(5):303–10.

    Article  CAS  PubMed  Google Scholar 

  30. Cohn J, Tognoni G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med. 2001;345(23):1667–75.

    Article  CAS  PubMed  Google Scholar 

  31. CIBIS II Investigators and Committees. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet. 1999;353(9146):9–13.

    Article  Google Scholar 

  32. MERIT-HF study group. Effect of metoprolol CR/XL in chronic heart failure: metoprolol CR/Xl randomised intervention trial in congestive heart failure (MERIT-HF). Lancet. 1999;353(9169):2001–7.

    Article  Google Scholar 

  33. Flather MD, Shibata MC, Coats AJS, Van Veldhuisen DJ, Parkhomenko A, Borbola J, et al. Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS). Eur Heart J. 2005;26(3):215–25.

    Article  CAS  PubMed  Google Scholar 

  34. The Digitalis Investigation Group. The effect of digoxin on mortality and morbidity in patients with heart failure. N Engl J Med. 1997;336(8):525–33.

    Article  Google Scholar 

  35. Rich MW, McSherry F, Williford WO, Yusuf S. Effect of age on mortality, hospitalizations and response to digoxin in patients with heart failure: the DIG study. J Am Coll Cardiol. 2001;38(3):806–13.

    Article  CAS  PubMed  Google Scholar 

  36. Pitt B, Zannad F, Remme W. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med. 1999;341(10):709–17.

    Article  CAS  PubMed  Google Scholar 

  37. Zannad F, McMurray J. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med. 2011;364(1):11–21.

    Article  CAS  PubMed  Google Scholar 

  38. McMurray JJV, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart. Eur Heart J. 2012;33(14):1787–847.

    Article  PubMed  Google Scholar 

  39. Cleland JGF, Tendera M, Adamus J, Freemantle N, Polonski L, Taylor J. The perindopril in elderly people with chronic heart failure (PEP-CHF) study. Eur Heart J. 2006;27(19):2338–45.

    Article  CAS  PubMed  Google Scholar 

  40. Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362(9386):777–81.

    Article  CAS  PubMed  Google Scholar 

  41. Massie BM, Carson PE, McMurray JJ, Komajda M, McKelvie R, Zile MR, et al. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med. 2008;359(23):2456–67.

    Article  CAS  PubMed  Google Scholar 

  42. Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol [Internet]. 2013 [cited 2013 Jul 12]; J Am Coll. Available from: http://jvsmedicscorner.com/Medicine_files/ACCF%3AAHAGuideline for the Management of Heart Failure 2013.pdf

  43. Rose E, Gelijns A. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345(20):1435–43.

    Article  CAS  PubMed  Google Scholar 

  44. Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009;361(23):2241–51.

    Article  CAS  PubMed  Google Scholar 

  45. Adamson RM, Stahovich M, Chillcott S, Baradarian S, Chammas J, Jaski B, et al. Clinical strategies and outcomes in advanced heart failure patients older than 70 years of age receiving the HeartMate II left ventricular assist device: a community hospital experience. J Am Coll Cardiol. 2011;57(25):2487–95.

    Article  PubMed  Google Scholar 

  46. Anker SD, Rauchhaus M. Heart failure as a metabolic problem. Eur J Heart Fail. 1999;1(2):127–31.

    Article  CAS  PubMed  Google Scholar 

  47. Berry C. Catabolism in chronic heart failure. Eur Heart J. 2000;21(7):521–32.

    Article  CAS  PubMed  Google Scholar 

  48. Anker S, Rauchhaus M. Insights into the pathogenesis of chronic heart failure: immune activation and cachexia. Curr Opin Cardiol. 1999;14(3):211.

    Article  CAS  PubMed  Google Scholar 

  49. Anker S, Chua T, Ponikowski P. Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. Circulation. 1997;96(2):526–34.

    Article  CAS  PubMed  Google Scholar 

  50. Poehlman ET, Scheffers J, Gottlieb SS, Fisher ML, Vaitekevicius P. Brief communications increased resting metabolic rate in patients with congestive heart failure. Ann Intern Med. 2012;121(11):860–2.

    Article  Google Scholar 

  51. Freeman LM, Roubenoff R. The nutrition implications of cardiac cachexia. Nutr Rev. 2009;52(10):340–7.

    Article  Google Scholar 

  52. Anker SD, Ponikowski P, Varney S, Chua TP, Clark AL, Webb-Peploe KM, et al. Wasting as independent risk factor for mortality in chronic heart failure. Lancet. 1997;349(9058):1050–3.

    Article  CAS  PubMed  Google Scholar 

  53. von Haehling S, Lainscak M. Cardiac cachexia: a systematic overview. Pharmacol Ther. 2009;121(3):227–52.

    Article  CAS  Google Scholar 

  54. Murdoch DR, Rooney E, Dargie HJ, Shapiro D, Morton JJ, McMurray JJ. Inappropriately low plasma leptin concentration in the cachexia associated with chronic heart failure. Heart. 1999;82(3):352–6.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  55. Lund LH, Williams JJ, Freda P, LaManca JJ, LeJemtel TH, Mancini DM. Ghrelin resistance occurs in severe heart failure and resolves after heart transplantation. Eur J Heart Fail. 2009;11(8):789–94.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  56. Strassburg S, Anker SD. Metabolic and immunologic derangements in cardiac cachexia: where to from here? Heart Fail Rev. 2006;11(1):57–64.

    Article  CAS  PubMed  Google Scholar 

  57. Nagaya N, Moriya J, Yasumura Y, Uematsu M, Ono F, Shimizu W, et al. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation. 2004;110(24):3674–9.

    Article  CAS  PubMed  Google Scholar 

  58. Vila G, Grimm G, Resl M, Heinisch B, Einwallner E, Esterbauer H, et al. B-type natriuretic peptide modulates ghrelin, hunger, and satiety in healthy men. Diabetes. 2012;61(10):1–5.

    Article  CAS  Google Scholar 

  59. Zhao SP, Zeng LH. Elevated plasma levels of tumor necrosis factor in chronic heart failure with cachexia. Int J Cardiol. 1997;58(3):257–61.

    Article  CAS  PubMed  Google Scholar 

  60. Bobbert P, Jenke A, Bobbert T, Kühl U, Rauch U, Lassner D, et al. High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy. Eur J Heart Fail. 2012;14(11):1265–75.

    Article  CAS  PubMed  Google Scholar 

  61. Fukagawa N. Sarcopenia in aging humans: the impact of menopause and disease. J Gerontol A Biol Sci Med Sci. 1995;50A:73–7.

    Article  Google Scholar 

  62. King D, Smith ML, Chapman TJ, Stockdale HR, Lye M. Fat malabsorption in elderly patients with cardiac cachexia. Age Ageing. 1996;25(2):144–9.

    Article  CAS  PubMed  Google Scholar 

  63. King D, Smith ML, Lye M. Gastro-intestinal protein loss in elderly patients with cardiac cachexia. Age Ageing. 1996;25(3):221–3.

    Article  CAS  PubMed  Google Scholar 

  64. Gomes MER, Mulder A, Bellersen L, Verheugt FWA, Smits P, Tack CJ. Alpha-receptor blockade improves muscle perfusion and glucose uptake in heart failure. Eur J Heart Failure [Internet]. 2010 [cited 2013 Sep 15];12(10):1061–6. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2980999&tool=pmcentrez&rendertype=abstract

  65. Aquilani R, Opasich C, Verri M, Boschi F, Febo O, Pasini E, et al. Is nutritional intake adequate in chronic heart failure patients? J Am Coll Cardiol [Internet]. 2003 [cited 2013 Sep 15];42(7):1218–23. Available from: http://linkinghub.elsevier.com/retrieve/pii/S073510970300946X

  66. Anker SD, Negassa A, Coats AJS, Afzal R, Poole-Wilson PA, Cohn JN. Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study. Lancet. 2003;361:1077–83.

    Article  CAS  PubMed  Google Scholar 

  67. Hryniewicz K, Androne ANAS, Hudaihed A, Katz SD. Partial reversal of cachexia by b-adrenergic receptor blocker therapy in patients with chronic heart failure. J Card Fail. 2003;9(6):464–8.

    Article  CAS  PubMed  Google Scholar 

  68. Adigun A, Ajayi A. The effects of enalapril-digoxin-diuretic combination therapy on nutritional and anthropometric indices in chronic congestive heart failure: preliminary findings in cardiac cachexia. Eur J Heart Fail. 2001;3:359–63.

    Article  CAS  PubMed  Google Scholar 

  69. Mann DL, McMurray JJV, Packer M, Swedberg K, Borer JS, Colucci WS, et al. Targeted anticytokine therapy in patients with chronic heart failure: results of the Ranodimized Etanercept Worldwide Evaluation (RENEWAL). Circulation. 2004;109:1594–602.

    Article  CAS  PubMed  Google Scholar 

  70. Broqvist M, Arnqvist H. Nutritional assessment and muscle energy metabolism in severe chronic congestive heart failure—effects of long-term dietary supplementation. Eur Heart J. 1994;15:1641–50.

    CAS  PubMed  Google Scholar 

  71. Heymsfield B, Casper K. Congestive continuous heart failure: clinical management by use of continuous nasoenteric feeding. Am J Clin Nutr. 1989;50(3):539–44.

    CAS  PubMed  Google Scholar 

  72. Paccagnella A, Calò MA, Caenaro G, Salandin V, Jus P, Simini G, et al. Cardiac cachexia: preoperative and postoperative nutrition management. JPEN J Parenter Enteral Nutr. 1994;18(5):409–16.

    Article  CAS  PubMed  Google Scholar 

  73. Morrison W. Skeletal muscle and whole body protein turnover in cardiac cachexia: influence of branched-chain amino acid administration. Eur J Clin Invest. 1988;18(6):648–54.

    Article  CAS  PubMed  Google Scholar 

  74. Aquilani R, Viglio S, Iadarola P, Opasich C, Testa A, Dioguardi FS, et al. Oral amino acid supplements improve exercise capacities in elderly patients with chronic heart failure. Am J Cardiol. 2008;101(11A):104E–10.

    Article  CAS  PubMed  Google Scholar 

  75. Tavazzi L, Maggioni A, Marchioli R. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet. 2008;372(9645):1223–30.

    Article  PubMed  CAS  Google Scholar 

  76. Garza CA, Pellikka P, Somers VK, et al. Structural and functional changes in left and right ventricles after major weight loss following bariatric surgery for morbid obesity. Am J Cardiol. 2010;105(4):550–6.

    Article  PubMed  Google Scholar 

  77. Garza CA, Pellikka PA, Somers VK, Sarr MG, Seward JB, Collazo-Clavell ML, et al. Major weight loss prevents long-term left atrial enlargement in patients with morbid and extreme obesity. Eur J Echocardiogr. 2008;9(5):587–93.

    Article  PubMed Central  PubMed  Google Scholar 

  78. Lin CH, Kurup S, Herrero P, Schechtman KB, Eagon JC, Klein S, et al. Myocardial oxygen consumption change predicts left ventricular relaxation improvement in obese humans after weight loss. Obesity (Silver Spring, MD). 2011;19(9):1804–12.

    Article  CAS  Google Scholar 

  79. Varli M, Turhan S, Aras S, Atli T, Erdogan G. Effects of weight loss on ventricular systolic and diastolic functions and left ventricular mass assessed by tissue doppler imaging in obese geriatric women: preliminary report. Aging Clin Exp Res. 2010;22(3):206–11.

    Article  PubMed  Google Scholar 

  80. Horwich TB, Fonarow GC, Hamilton MA, MacLellan WR, Woo MA, Tillisch JH. The relationship between obesity and mortality in patients with heart failure. J Am Coll Cardiol. 2001;38(3):789–95.

    Article  CAS  PubMed  Google Scholar 

  81. Casas-Vara A, Santolaria F, Fernández-Bereciartúa A, González-Reimers E, García-Ochoa A, Martínez-Riera A. The obesity paradox in elderly patients with heart failure: analysis of nutritional status. Nutrition. 2012;28(6):616–22.

    Article  PubMed  Google Scholar 

  82. Huynh B, Rovner A, Rich M. Long-term survival in elderly patients hospitalized for heart failure: 14-year follow-up from a prospective randomized trial. Arch Intern Med. 2006;166:1892–8.

    Article  PubMed  Google Scholar 

  83. Konstam MA, Maggioni AP, Swedberg K, Udelson JE. Effects of oral tolvaptan in patients hospitalized for worsening heart failure The EVEREST outcome trial. JAMA. 2012;297(12):1319–31.

    Article  Google Scholar 

  84. Ghali J, Kadakia S, Cooper R, Ferlinz J. Precipitating factors leading to decompensation of heart failure. Arch Intern Med. 1988;148:20–3.

    Article  Google Scholar 

  85. Vinson JM, Rich MW, Sperry JC, Shah A, McNamara T. Early readmission of elderly patients with congestive heart failure. J Am Geriatr Soc. 1991;39(10):1045–6.

    Google Scholar 

  86. Witte KK, Clark AL. Micronutrients and their supplementation in chronic cardiac failure. An update beyond theoretical perspectives. Heart Fail Rev. 2006;11(1):65–74.

    Article  CAS  PubMed  Google Scholar 

  87. Gao X, Peng L, Adhikari C, Lin J, Zuo Z. Spironolactone reduced arrhythmia and maintained magnesium homeostasis in patients with congestive heart failure. J Card Fail. 2007;13(3):170–7.

    Article  CAS  PubMed  Google Scholar 

  88. Ramires FJ, Mansur A, Coelho O, Maranhão M, Gruppi CJ, Mady C, et al. Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. Am J Cardiol. 2000;85(10):1207–11.

    Article  CAS  PubMed  Google Scholar 

  89. Witte KK, Clark AL, Cleland JG. Chronic heart failure and micronutrients. J Am Coll Cardiol. 2001;37(7):1765–74.

    Article  CAS  PubMed  Google Scholar 

  90. Kopp SJ, Klevay LM, Feliksik JM, Feliksik JM. Physiological and metabolic characterization of a cardiomyopathy induced by chronic copper deficiency. Am J Physiol. 1983;245:h855–6.

    CAS  PubMed  Google Scholar 

  91. Lockitch G. Cardiomyopathy associated deficiency in a Caucasian with nonendemic. Am J Clin Nutr. 1990;52:572–7.

    CAS  PubMed  Google Scholar 

  92. Coudray C, Boucher F, Richard MJ, Arnaud J, De Leiris J, Favier A. Zinc deficiency, ethanol, and myocardial ischemia affect lipoperoxidation in rats. Biol Trace Elem Res. 1991;30(2):103–18.

    Article  CAS  PubMed  Google Scholar 

  93. Li Y, Huang T, Carlson E, Melov S. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet. 1995;11(4):376–81.

    Article  CAS  PubMed  Google Scholar 

  94. Golik A, Cohen N, Ramot Y, Maor J, Moses R, Weissgarten J, et al. Type II diabetes mellitus, congestive heart failure, and zinc metabolism. Biol Trace Elem Res. 1993;39(2–3):171–5.

    Article  CAS  PubMed  Google Scholar 

  95. Anker SD, Comin Colet J, Filippatos G, Willenheimer R, Dickstein K, Drexler H, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009;361(25):2436–48.

    Article  CAS  PubMed  Google Scholar 

  96. Liu P, Olivieri N. Iron overload cardiomyopathies: new insights into an old disease. Cardiovasc Drugs Ther. 1994;8(1):101–10.

    Article  CAS  PubMed  Google Scholar 

  97. Djoenaidi W, Notermans S, Dunda G. Beriberi cardiomyopathy. Eur J Clin Nutr. 1992;46(3):227–34.

    CAS  PubMed  Google Scholar 

  98. Shimon I, Almog S, Vered Z, Seligmann H, Shefi M, Peleg E, et al. Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy. Am J Med. 1995;98(5):485–90.

    Article  CAS  PubMed  Google Scholar 

  99. Seligmann H, Halkin H. Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study. Am J Med. 1991;91(2):151–5.

    Article  CAS  PubMed  Google Scholar 

  100. Zangen A, Botzer D, Zangen R, Shainberg A. Furosemide and digoxin inhibit thiamine uptake in cardiac cells. Eur J Pharmacol. 1998;361(1):151–5.

    Article  CAS  PubMed  Google Scholar 

  101. Ting HH, Timimi FK, Boles KS, Creager SJ, Ganz P, Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest. 1996;97(1):22–8.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  102. Gokce N, Keaney JF, Frei B, Holbrook M, Olesiak M, Zachariah BJ, et al. Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1999;99(25):3234–40.

    Article  CAS  PubMed  Google Scholar 

  103. Hornig B, Arakawa N, Kohler C, Drexler H. Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure. Circulation. 1998;97(4):363–8.

    Article  CAS  PubMed  Google Scholar 

  104. Khaw K-T, Bingham S, Welch A, Luben R, Wareham N, Oakes S, et al. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. Lancet. 2001;357(9257):657–63.

    Article  CAS  PubMed  Google Scholar 

  105. Gale C, Martyn C, Winter P, Cooper C. Vitamin C and risk of death from stroke and coronary heart disease in cohort of elderly people. BMJ. 1995;310(6994):1563–6.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  106. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology. 1992;3(3):194–202.

    Article  CAS  PubMed  Google Scholar 

  107. Calzada C, Bruckdorfer KR, Rice-Evans CA. The influence of antioxidant nutrients on platelet function in healthy volunteers. Atherosclerosis. 1997;128(1):97–105.

    Article  CAS  PubMed  Google Scholar 

  108. Stampfer M, Hennekens CH, Manson JE, Colditz G, Rosner B, Willett W. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med. 1993;328(20):1444–9.

    Article  CAS  PubMed  Google Scholar 

  109. Losonczy K, Harris B, Havlik R. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the established populations for epidemiologic studies of the elderly. Am J Clin Nutr. 1996;64:190–6.

    CAS  PubMed  Google Scholar 

  110. Kushi L, Folsom A. Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women. N Engl J Med. 1996;334(18):1156–62.

    Article  CAS  PubMed  Google Scholar 

  111. Eidelman RS, Hollar D, Hebert PR, Lamas GA, Hennekens CH. Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease. Arch Intern Med. 2004;164(14):1552–6.

    Article  CAS  PubMed  Google Scholar 

  112. Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142(1):37–47.

    Article  CAS  PubMed  Google Scholar 

  113. Lonn E, Bosch J, Yusuf S, Sheridan P, Pogue J, Arnold JM, et al. Effects of long-term vitamin E supplementation on cardiovascular events and cancer. JAMA. 2005;293(11):1338–47.

    Article  PubMed  Google Scholar 

  114. Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA. 1993;270(22):2693–8.

    Article  CAS  PubMed  Google Scholar 

  115. Bostom AG, Rosenberg IH, Silbershatz H, Jacques PF, Selhub J, D’Agostino RB, et al. Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the Framingham Study. Ann Intern Med. 1999;131(5):352–5.

    Article  CAS  PubMed  Google Scholar 

  116. Bots M, Launer L, Lindemans J. Homocysteine and short-term risk of myocardial infarction and stroke in the elderly: the Rotterdam Study. Arch Intern Med. 1999;159:38–44.

    Article  CAS  PubMed  Google Scholar 

  117. Eikelboom JW, Lonn E, Genest J, Hankey G, Yusuf S. Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence. Ann Intern Med. 1999;131(5):363–75.

    Article  CAS  PubMed  Google Scholar 

  118. Herrmann M, Taban-Shomal O, Hübner U, Böhm M, Herrmann W. A review of homocysteine and heart failure. Eur J Heart Fail. 2006;8(6):571–6.

    Article  CAS  PubMed  Google Scholar 

  119. Weishaar R, Simpson R. Involvement of vitamin D3 with cardiovascular function. II. Direct and indirect effects. Am J Physiol Endocrinol Metab. 1987;253:e675–86.

    CAS  Google Scholar 

  120. MacLaughlin J, Holick MF. Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest. 1985;76(4):1536–8.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  121. Field MH. Hyperparathyroidism in congestive heart failure. Am J Med. 1999;107(1):102–3.

    Article  CAS  PubMed  Google Scholar 

  122. Boxer R, Kenny A, Cheruvu V. Serum 25-hydroxyvitamin D concentration is associated with functional capacity in older adults with heart failure. Am Heart J. 2010;160(5):893–9.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  123. Witham MD, Crighton LJ, Gillespie ND, Struthers AD, McMurdo MET. The effects of vitamin D supplementation on physical function and quality of life in older patients with heart failure: a randomized controlled trial. Circ Heart Fail. 2010;3(2):195–201.

    Article  CAS  PubMed  Google Scholar 

  124. Boden W, Probstfield J, Anderson T. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med. 2011;365(24):2255–67.

    Article  PubMed  CAS  Google Scholar 

  125. Tavani A, Negri E, D’Avanzo B, La Vecchia C. Beta-carotene intake and risk of nonfatal acute myocardial infarction in women. Eur J Epidemiol. 1997;13(6):631–7.

    Article  CAS  PubMed  Google Scholar 

  126. Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B, Cook NR, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996;334(18):1145–9.

    Article  CAS  PubMed  Google Scholar 

  127. McMurray JJV, Dunselman P, Wedel H, Cleland JG, Lindberg M, Hjalmarson A, et al. Coenzyme Q10, rosuvastatin, and clinical outcomes in heart failure: a pre-specified substudy of CORONA (controlled rosuvastatin multinational study in heart failure). J Am Coll Cardiol. 2010;56(15):1196–204.

    Article  CAS  PubMed  Google Scholar 

  128. De Pinieux G, Chariot P, Ammi-Saïd M, Louarn F, Lejonc JL, Astier A, et al. Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio. Br J Clin Pharmacol. 1996;42(3):333–7.

    Article  CAS  PubMed  Google Scholar 

  129. Hofman-Bang C, Rehnqvist N, Swedberg K, Wiklund I, Aström H. Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. The Q10 Study Group. J Card Fail. 1995;1(2):101–7.

    Article  CAS  PubMed  Google Scholar 

  130. Watson PS, Scalia GM, Galbraith A, Burstow DJ, Bett N, Aroney CN. Lack of effect of coenzyme Q on left ventricular function in patients with congestive heart failure. J Am Coll Cardiol. 1999;33(6):1549–52.

    Article  CAS  PubMed  Google Scholar 

  131. Weant KA, Smith KM. The role of coenzyme Q10 in heart failure. Ann Pharmacother. 2005;39(9):1522–6.

    Article  CAS  PubMed  Google Scholar 

  132. Khatta M, Alexander BS, Krichten CM, Fisher ML, Freudenberger R, Robinson SW, et al. The effect of coenzyme Q10 in patients with congestive heart failure. Ann Intern Med. 2000;132(8):636–40.

    Article  CAS  PubMed  Google Scholar 

  133. Belardinelli R, Muçaj A, Lacalaprice F, Solenghi M, Seddaiu G, Principi F, et al. Coenzyme Q10 and exercise training in chronic heart failure. Eur Heart J. 2006;27(22):2675–81.

    Article  CAS  PubMed  Google Scholar 

  134. Nawarskas JJ. HMG-CoA reductase inhibitors and coenzyme Q10. Cardiol Rev. 2005;13(2):76–9.

    Article  PubMed  Google Scholar 

  135. Anand I, Chandrashekhan Y, De Giuli F, Pasini E, Mazzoletti A, Confortini R, et al. Acute and chronic effects of propionyl-L-carnitine on the hemodynamics, exercise capacity, and hormones in patients with congestive heart failure. Cardiovasc Drug Ther. 1998;12(3):291–9.

    Article  CAS  Google Scholar 

  136. Study on propionyl-L-carnitine in chronic heart failure. Eur Heart J. 1999;20(1):70–6.

    Google Scholar 

  137. Gordon A, Hultman E, Kaijser L, Kristjansson S, Rolf CJ, Nyquist O, et al. Creatine supplementation in chronic heart failure increases skeletal muscle creatine phosphate and muscle performance. Cardiovasc Res. 1995;30(3):413–8.

    Article  CAS  PubMed  Google Scholar 

  138. Witte KKA, Nikitin NP, Parker AC, von Haehling S, Volk HD, Anker SD, et al. The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure. Eur Heart J. 2005;26(21):2238–44.

    Article  CAS  PubMed  Google Scholar 

  139. Soukoulis V, Dihu JB, Sole M, Anker SD, Cleland J, Fonarow GC, et al. Micronutrient deficiencies an unmet need in heart failure. J Am Coll Cardiol. 2009;54(18):1660–73.

    Article  CAS  PubMed  Google Scholar 

  140. Holdy K, Dembitsky W, Eaton LL, Chillcott S, Stahovich M, Rasmusson B, et al. Nutrition assessment and management of left ventricular assist device patients. J Heart Lung Transplant. 2005;24(10):1690–6.

    Article  PubMed  Google Scholar 

  141. Otten JJ, Pitzi Hellwig J, Meyers LD. Dietary reference intakes essential guide nutrient requirements. Washington, DC: The National Academies Press; 2006.

    Google Scholar 

  142. Dinicolantonio JJ, DiPasquale P, Taylor RS, Hackam DG. Low sodium versus normal sodium diets in systolic heart failure: systematic review and meta-analysis. Heart. 2013;99(11):820.

    Article  Google Scholar 

  143. Aguilar D, Skali H, Moyé LA, Lewis EF, Gaziano JM, Rutherford JD, et al. Alcohol consumption and prognosis in patients with left ventricular systolic dysfunction after a myocardial infarction. J Am Coll Cardiol. 2004;43(11):2015–21.

    Article  CAS  PubMed  Google Scholar 

  144. Cooper HA, Exner DV, Domanski MJ. Light-to-moderate alcohol consumption and prognosis in patients with left ventricular systolic dysfunction. J Am Coll Cardiol. 2000;35(7):1753–9.

    Article  CAS  PubMed  Google Scholar 

  145. Mostofsky E, Rice MS, Levitan EB, Mittleman MA. Habitual coffee consumption and risk of heart failure: a dose-response meta-analysis. Circ Heart Fail. 2012;5(4):401–5.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  146. Notarius CF, Morris B, Floras JS. Caffeine prolongs exercise duration in heart failure. J Card Fail. 2006;12(3):220–6.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine, 660 South Euclid Ave., Campus Box 8086, St. Louis, MO, 63110, USA

    Justin M. Vader M.D.

  2. Cardiovascular Division, Department of Internal Medicine, Barnes-Jewish Hospital, 660 S. Euclid Avenue, Box 8086, St. Louis, MO, 63110, USA

    Christopher L. Holley M.D., Ph.D.

  3. Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8086, St. Louis, MO, 63110, USA

    Michael W. Rich M.D.

Authors
  1. Justin M. Vader M.D.
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  2. Christopher L. Holley M.D., Ph.D.
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  3. Michael W. Rich M.D.
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Correspondence to Michael W. Rich M.D. .

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Editors and Affiliations

  1. Geriatric Research, Education, and Clinical Center, Department of Medicine, Durham VA Medical Center, Duke University Medical Center, Durham, North Carolina, USA

    Connie Watkins Bales

  2. Departments of Medicine and Health Care Organization and Policy Translational Nutrition and Aging Program, University of Alabama at Birmingham, Birmingham, Alabama, USA

    Julie L. Locher

  3. Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA

    Edward Saltzman

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Vader, J.M., Holley, C.L., Rich, M.W. (2015). Chronic Heart Failure. In: Bales, C., Locher, J., Saltzman, E. (eds) Handbook of Clinical Nutrition and Aging. Nutrition and Health. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1929-1_13

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