Clinical Scenario: Bladder Preservation

  • Albert J. ChangEmail author
  • Maurice Marcel Garcia
  • Mack RoachIII


Multi-modality bladder preservation with maximal transurethral resection of the bladder tumor (TURBT) followed by definitive chemoradiation is becoming increasingly popular and an attractive option to radical cystectomy for treatment of muscle invasive bladder cancer. Ideal candidates are patients with unifocal, T2 disease undergoing maximal TURBT with no gross residual, patients with tumors <5 cm, and patients with good bladder function. Bladder preservation treatment is well-tolerated, offers similar survival outcomes to radical cystectomy (5y OS 40–60 %), and approximately two-thirds of patients are cured 5 years after treatment. Studies have demonstrated that the majority of patients undergoing bladder preservation are satisfied with their quality of life with minimal urinary distress.


Bladder Radiation Chemotherapy Cystectomy TURBT 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Albert J. Chang
    • 1
    Email author
  • Maurice Marcel Garcia
    • 2
  • Mack RoachIII
    • 1
  1. 1.Department of Radiation Oncology, Helen Diller Family Comprehensive Cancer CenterUniversity of California, San FranciscoSan FranciscoUSA
  2. 2.Department of Urology, (Moffit-Long, Mount Zion), San Francisco General Hospital and The San Francisco Veteran’s Adminstration HospitalUniversity of California San FranciscoSan FranciscoUSA

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