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Understanding Interventional Bronchoscopy

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Book cover Diagnostic Tests in Pediatric Pulmonology

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Abstract

Pediatric flexible bronchoscopy as a diagnostic modality has become a standard tool in the armamentarium of the modern pediatric pulmonologist. However the feasibility of interventions through flexible bronchoscopy is emerging slowly as it is limited not only by the size of the pediatric bronchoscope and its working channel but also by the demarcation lines between flexible and rigid bronchoscopy.

We organize this chapter on interventional bronchoscopy into the following broad topics:

  1. 1.

    Use of flexible bronchoscopy for acquisition of diagnostic material.

  2. 2.

    Bronchoscopy for removal of obstructive, noxious, or damaging materials from the airway or the lung.

  3. 3.

    Management of the narrowed or obstructed airway: debridement, dilation, and stenting.

  4. 4.

    Use of bronchoscopy for other procedures including: sealing of fistulae and pneumothorax, control of diffuse alveolar hemorrhage, and segmental bronchography.

  5. 5.

    New horizons: a discussion on recent reports on fetal bronchoscopy as a novel interventional approach.

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References

  1. Donato LL, Mai Hong Tran T, Ammouche C, Musani AI. Pediatric interventional bronchoscopy. Clin Chest Med. 2013;34:569–82.

    Article  PubMed  Google Scholar 

  2. Colin AA, Walz DA. Techniques and technical issues: special procedures. In: Priftis KN, Anthracopoulos MB, Eber E, Koumbourlis A, Wood RE, editors. Paediatric bronchoscopy. Basel: Karger AG; 2010. p. 42–53.

    Chapter  Google Scholar 

  3. Nicolai T. The role of rigid and flexible bronchoscopy in children. Paediatr Respir Rev. 2011;12:190–5.

    Article  CAS  PubMed  Google Scholar 

  4. Salva PS, Theroux C, Schwartz D. Safety of endobronchial biopsy in 170 children with chronic respiratory symptoms. Thorax. 2003;58:1058–60.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  5. Colin AA, Ali-Dinar T. Endobronchial biopsy in childhood. Chest. 2007;131:1626–7.

    Article  PubMed  Google Scholar 

  6. Greene CL, Reemtsen B, Polimenakos A, Horn M, Wells W. Role of clinically indicated transbronchial lung biopsies in the management of pediatric post-lung transplant patients. Ann Thorac Surg. 2008;86:198–203.

    Article  PubMed  Google Scholar 

  7. Whitehead B, Scott JP, Helms P, et al. Technique and use of transbronchial biopsy in children and adolescents. Pediatr Pulmonol. 1992;12:240–6.

    Article  CAS  PubMed  Google Scholar 

  8. Fan LL, Kozinetz CA, Wojtczak HA, Chatfield BA, Cohen AH, Rothenberg SS. Diagnostic value of transbronchial, thoracoscopic, and open lung biopsy in immunocompetent children with chronic interstitial lung disease. J Pediatr. 1997;131:565–9.

    Article  CAS  PubMed  Google Scholar 

  9. Barbato A, Panizzolo C, Cracco A, de Blic J, Dinwiddie R, Zach M. Interstitial lung disease in children: a multicentre survey on diagnostic approach. Eur Respir J. 2000;16:509–13.

    Article  CAS  PubMed  Google Scholar 

  10. Morell F, Reyes L, Domenech G, De Gracia J, Majo J, Ferrer J. Diagnoses and diagnostic procedures in 500 consecutive patients with clinical suspicion of interstitial lung disease. Arch Bronconeumol. 2008;44:185–91.

    PubMed  Google Scholar 

  11. Tagliaferro T, Michelin E, Snijders D, Barbato A. Endobronchial and transbronchial biopsies in children. Expert Rev Respir Med. 2008;2:245–51.

    Article  PubMed  Google Scholar 

  12. Barbato A, Panizzolo C. Chronic interstitial lung disease in children. Paediatr Respir Rev. 2000;1:172–8.

    Article  CAS  PubMed  Google Scholar 

  13. Steinfort DP, Wurzel D, Irving LB, Ranganathan SC. Endobronchial ultrasound in pediatric pulmonology. Pediatr Pulmonol. 2009;44:303–8.

    Article  PubMed  Google Scholar 

  14. Dango S, Cucuruz B, Mayer O, et al. Detection of disseminated tumour cells in mediastinoscopic lymph node biopsies and endobronchial ultrasonography-guided transbronchial needle aspiration in patients with suspected lung cancer. Lung Cancer. 2010;68:383–8.

    Article  CAS  PubMed  Google Scholar 

  15. Wurzel DF, Steinfort DP, Massie J, Ryan MM, Irving LB, Ranganathan SC. Paralysis and a perihilar protuberance: an unusual presentation of sarcoidosis in a child. Pediatr Pulmonol. 2009;44:410–4.

    Article  PubMed  Google Scholar 

  16. Goussard P, Gie RP, Kling S, et al. The diagnostic value and safety of transbronchial needle aspiration biopsy in children with mediastinal lymphadenopathy. Pediatr Pulmonol. 2010;45:1173–9.

    Article  CAS  PubMed  Google Scholar 

  17. Babiak A, Hetzel J, Krishna G, et al. Transbronchial cryobiopsy: a new tool for lung biopsies. Respiration. 2009;78:203–8.

    Article  PubMed  Google Scholar 

  18. Fruchter O, Fridel L, Rosengarten D, Raviv Y, Rosanov V, Kramer MR. Transbronchial cryo-biopsy in lung transplantation patients: first report. Respirology. 2013;18:669–73.

    Article  PubMed  Google Scholar 

  19. Leading causes of death reports. 10 leading causes of nonfatal unintentional injury, United States 2007, all races, both sexes, ages <1. Web-based injury statistics query and reporting system (WISQARS) 2007. Center for Disease Control, 2007. http://www.cdc.gov/ncipc/wisqars

  20. Boufersaoui A, Smati L, Benhalla KN, et al. Foreign body aspiration in children: experience from 2624 patients. Int J Pediatr Otorhinolaryngol. 2013;77:1683–8.

    Article  CAS  PubMed  Google Scholar 

  21. Heyer CM, Bollmeier ME, Rossler L, et al. Evaluation of clinical, radiologic, and laboratory prebronchoscopy findings in children with suspected foreign body aspiration. J Pediatr Surg. 2006;41:1882–8.

    Article  PubMed  Google Scholar 

  22. Martinot A, Closset M, Marquette CH, et al. Indications for flexible versus rigid bronchoscopy in children with suspected foreign-body aspiration. Am J Respir Crit Care Med. 1997;155:1676–9.

    Article  CAS  PubMed  Google Scholar 

  23. Wood RE. Flexible bronchoscopy to remove foreign bodies in children – yes, maybe – but… J Bronchol. 1994;1:87.

    Google Scholar 

  24. Shubha AM, Das K. Tracheobronchial foreign bodies in infants. Int J Pediatr Otorhinolaryngol. 2009;73:1385–9.

    Article  CAS  PubMed  Google Scholar 

  25. Swanson KL, Prakash UB, Midthun DE, et al. Flexible bronchoscopic management of airway foreign bodies in children. Chest. 2002;121:1695–700.

    Article  PubMed  Google Scholar 

  26. Mehta D, Mehta C, Bansal S, Singla S, Tangri N. Flexible bronchoscopic removal of a three piece foreign body from a child's bronchus. Australas Med J. 2012;5:227–30.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  27. Lando T, Cahill AM, Elden L. Distal airway foreign bodies: importance of a stepwise approach, knowledge of equipment and utilization of other services’ expertise. Int J Pediatr Otorhinolaryngol. 2011;75:968–72.

    Article  CAS  PubMed  Google Scholar 

  28. Jabbardarjani H, Kiani A, Arab A, Masjedi M. Foreign body removal using bronchoscopy and argon plasma coagulation. Arch Iran Med. 2010;13:150–2.

    PubMed  Google Scholar 

  29. Hockstein NG, Jacobs IN. Flexible bronchoscopic removal of a distal bronchial foreign body with cinefluoroscopic guidance. Ann Otol Rhinol Laryngol. 2004;113:863–5.

    Article  PubMed  Google Scholar 

  30. Nwaejike N, Khan Z, Villaquiran J, Awan YM, Rahamim J. Use of an image intensifier to remove a challenging foreign body in a segmental bronchiole. Ann R Coll Surg Engl. 2010;92:W38–40.

    Article  CAS  PubMed  Google Scholar 

  31. Naguib ML, Streetman DS, Clifton S, Nasr SZ. Use of laryngeal mask airway in flexible bronchoscopy in infants and children. Pediatr Pulmonol. 2005;39:56–63.

    Article  PubMed  Google Scholar 

  32. Avital A, Gozal D, Uwyyed K, Springer C. Retrieval of spirated foreign bodies in children using a flexible bronchoscope and a laryngeal mask airway. J Bronchol. 2002;9:6–9.

    Article  Google Scholar 

  33. Madsen P, Shah SA, Rubin BK. Plastic bronchitis: new insights and a classification scheme. Paediatr Respir Rev. 2005;6:292–300.

    Article  PubMed  Google Scholar 

  34. Shah PL, Hansell D, Lawson PR, Reid KB, Morgan C. Pulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis. Thorax. 2000;55:67–77.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  35. Mallory Jr GB. Surfactant proteins: role in lung physiology and disease in early life. Paediatr Respir Rev. 2001;2:151–8.

    Article  PubMed  Google Scholar 

  36. Rossi GA. Bronchoalveolar lavage in the investigation of disorders of the lower respiratory tract. Eur J Respir Dis. 1986;69:293–315.

    CAS  PubMed  Google Scholar 

  37. Wood RE. Whole Lung Lavage. In: Priftis KN, Anthracopoulos MB, Eber E, Koumbourlis A, Wood RE, editors. Paediatric bronchoscopy. Basel: Karger; 2010. p. 75–82.

    Chapter  Google Scholar 

  38. Reiter K, Schoen C, Griese M, Nicolai T. Whole-lung lavage in infants and children with pulmonary alveolar proteinosis. Paediatr Anaesth. 2010;20:1118–23.

    Article  PubMed  Google Scholar 

  39. Mahut B, Delacourt C, Scheinmann P, et al. Pulmonary alveolar proteinosis: experience with eight pediatric cases and a review. Pediatrics. 1996;97:117–22.

    CAS  PubMed  Google Scholar 

  40. Dogru D, Yalcin E, Aslan AT, et al. Successful unilateral partial lung lavage in a child with pulmonary alveolar proteinosis. J Clin Anesth. 2009;21:127–30.

    Article  PubMed  Google Scholar 

  41. Ciravegna B, Sacco O, Moroni C, et al. Mineral oil lipoid pneumonia in a child with anoxic encephalopathy: treatment by whole lung lavage. Pediatr Pulmonol. 1997;23:233–7.

    Article  CAS  PubMed  Google Scholar 

  42. Sias SM, Daltro PA, Marchiori E, et al. Clinic and radiological improvement of lipoid pneumonia with multiple bronchoalveolar lavages. Pediatr Pulmonol. 2009;44:309–15.

    Article  PubMed  Google Scholar 

  43. Kapur N, Slater A, McEniery J, Greer ML, Masters IB, Chang AB. Therapeutic bronchoscopy in a child with sand aspiration and respiratory failure from near drowning-case report and literature review. Pediatr Pulmonol. 2009;44:1043–7.

    Article  CAS  PubMed  Google Scholar 

  44. Godambe SA, Mack JW, Chung DS, Lindeman R, Lillehei CW, Colin AA. Iatrogenic pleuropulmonary charcoal instillation in a teenager. Pediatr Pulmonol. 2003;35:490–3.

    Article  PubMed  Google Scholar 

  45. Soong WJ, Jeng MJ, Lee YS, Tsao PC, Yang CF, Soong YH. Pediatric obstructive fibrinous tracheal pseudomembrane-characteristics and management with flexible bronchoscopy. Int J Pediatr Otorhinolaryngol. 2011;75:1005–9.

    Article  PubMed  Google Scholar 

  46. Colin AA, Tsiligiannis T, Nose V, Waltz DA. Membranous obliterative bronchitis: a proposed unifying model. Pediatr Pulmonol. 2006;41:126–32.

    Article  PubMed  Google Scholar 

  47. Quizon A, Minic P, Pohunek P, Tal A, Colin AA. Obliterative lower airway lesions in childhood: Bronchoscopic diagnosis and clinical spectrum. Pediatr Pulmonol. 2014;49(3):E27–34 doi:10.1002/ppul.22775.

  48. McLaren CA, Elliott MJ, Roebuck DJ. Tracheobronchial intervention in children. Eur J Radiol. 2005;53:22–34.

    Article  PubMed  Google Scholar 

  49. Meng C, Yu HF, Ni CY, et al. Balloon dilatation bronchoplasty in management of bronchial stenosis in children with mycoplasma pneumonia. Zhonghua Er Ke Za Zhi. 2010;48:301–4.

    PubMed  Google Scholar 

  50. Hebra A, Powell DD, Smith CD, Othersen Jr HB. Balloon tracheoplasty in children: results of a 15-year experience. J Pediatr Surg. 1991;26:957–61.

    Article  CAS  PubMed  Google Scholar 

  51. Shitrit D, Kuchuk M, Zismanov V, Rahman NA, Amital A, Kramer MR. Bronchoscopic balloon dilatation of tracheobronchial stenosis: long-term follow-up. Eur J Cardiothorac Surg. 2010;38:198–202.

    Article  PubMed  Google Scholar 

  52. Lund ME, Force S. Airway stenting for patients with benign airway disease and the food and drug administration advisory: a call for restraint. Chest. 2007;132:1107–8.

    Article  PubMed  Google Scholar 

  53. Fayon M, Donato L, de Blic J, et al. French experience of silicone tracheobronchial stenting in children. Pediatr Pulmonol. 2005;39:21–7.

    Article  PubMed  Google Scholar 

  54. Loeff DS, Filler RM, Gorenstein A, et al. A new intratracheal stent for tracheobronchial reconstruction: experimental and clinical studies. J Pediatr Surg. 1988;23:1173–7.

    Article  CAS  PubMed  Google Scholar 

  55. Vondrys D, Elliott MJ, McLaren CA, Noctor C, Roebuck DJ. First experience with biodegradable airway stents in children. Ann Thorac Surg. 2011;92:1870–4.

    Article  PubMed  Google Scholar 

  56. Bolliger CT, Mathur PN, Beamis JF, et al. ERS/ATS statement on interventional pulmonology. European Respiratory Society/American Thoracic Society. Eur Respir J. 2002;19:356–73.

    Article  CAS  PubMed  Google Scholar 

  57. Shinhar SY, Zablocki H, Madgy DN. Airway management in mucopolysaccharide storage disorders. Arch Otolaryngol Head Neck Surg. 2004;130:233–7.

    Article  PubMed  Google Scholar 

  58. Nicolai T. Airway stents in children. Pediatr Pulmonol. 2008;43:330–44.

    Article  CAS  PubMed  Google Scholar 

  59. Calkoen EE, Gabra HO, Roebuck DJ, Kiely E, Elliott MJ. Aortopexy as treatment for tracheo-bronchomalacia in children: an 18-year single-center experience. Pediatr Crit Care Med. 2011;12:545–51.

    Article  PubMed  Google Scholar 

  60. Kothari SS, Roy A, Sharma S, Bhan A. An infant with “dying spells”. Indian Heart J. 2003;55:78–80.

    PubMed  Google Scholar 

  61. Friedman E, Kennedy A, Neitzschman HR. Innominate artery compression of the trachea: an unusual cause of apnea in a 12-year-old boy. South Med J. 2003;96:1161–4.

    Article  PubMed  Google Scholar 

  62. Filler RM, Forte V, Chait P. Tracheobronchial stenting for the treatment of airway obstruction. J Pediatr Surg. 1998;33:304–11.

    Article  CAS  PubMed  Google Scholar 

  63. Stephens Jr KE, Wood DE. Bronchoscopic management of central airway obstruction. J Thorac Cardiovasc Surg. 2000;119:289–96.

    Article  PubMed  Google Scholar 

  64. Anton-Pacheco JL, Cabezali D, Tejedor R, et al. The role of airway stenting in pediatric tracheobronchial obstruction. Eur J Cardiothorac Surg. 2008;33:1069–75.

    Article  PubMed  Google Scholar 

  65. Wells WJ, Hussain NS, Wood JC. Stenting of the mainstem bronchus in children: a word of caution. Ann Thorac Surg. 2004;77:1420–2.

    Article  PubMed  Google Scholar 

  66. Geller KA, Wells WJ, Koempel JA, St John MA. Use of the Palmaz stent in the treatment of severe tracheomalacia. Ann Otol Rhinol Laryngol. 2004;113:641–7.

    Article  PubMed  Google Scholar 

  67. Peng YY, Soong WJ, Lee YS, Tsao PC, Yang CF, Jeng MJ. Flexible bronchoscopy as a valuable diagnostic and therapeutic tool in pediatric intensive care patients: a report on 5 years of experience. Pediatr Pulmonol. 2011;46:1031–7.

    Article  PubMed  Google Scholar 

  68. Chen N, Zhang J, Xu M, Wang YL, Pei YH. Inhibitory effect of mitomycin C on proliferation of primary cultured fibroblasts from human airway granulation tissues. Respiration. 2013;85:500–4.

    Article  CAS  PubMed  Google Scholar 

  69. Rojas-Solano J, Becker HD. Bronchoscopic application of mitomycin-C as adjuvant treatment for benign airway stenosis. J Bronchol Interv Pulmonol. 2011;18:53–5.

    Article  Google Scholar 

  70. Meier JD, Sulman CG, Almond PS, Holinger LD. Endoscopic management of recurrent congenital tracheoesophageal fistula: a review of techniques and results. Int J Pediatr Otorhinolaryngol. 2007;71:691–7.

    Article  PubMed  Google Scholar 

  71. Richter GT, Ryckman F, Brown RL, Rutter MJ. Endoscopic management of recurrent tracheoesophageal fistula. J Pediatr Surg. 2008;43:238–45.

    Article  PubMed  Google Scholar 

  72. Goussard P, Gie RP, Kling S, et al. Fibrin glue closure of persistent bronchopleural fistula following pneumonectomy for post-tuberculosis bronchiectasis. Pediatr Pulmonol. 2008;43: 721–5.

    Article  CAS  PubMed  Google Scholar 

  73. Hoffer FA, Bloom DA, Colin AA, Fishman SJ. Lung abscess versus necrotizing pneumonia: implications for interventional therapy. Pediatr Radiol. 1999;29:87–91.

    Article  CAS  PubMed  Google Scholar 

  74. Sawicki GS, Lu FL, Valim C, Cleveland RH, Colin AA. Necrotising pneumonia is an increasingly detected complication of pneumonia in children. Eur Respir J. 2008;31:1285–91.

    Article  CAS  PubMed  Google Scholar 

  75. Ratliff JL, Hill JD, Tucker H, Fallat R. Endobronchial control of bronchopleural fistulae. Chest. 1977;71:98–9.

    Article  CAS  PubMed  Google Scholar 

  76. Finch CK, Pittman AL. Use of fibrin glue to treat a persistent pneumothorax with bronchopleural fistula. Am J Health Syst Pharm. 2008;65:322–4.

    Article  PubMed  Google Scholar 

  77. Moody GN, Zeno BR. Localization and treatment of bronchopleural fistula through capnography. J Bronchol Interv Pulmonol. 2010;17:261–3.

    Article  Google Scholar 

  78. Wood DE, Cerfolio RJ, Gonzalez X, Springmeyer SC. Bronchoscopic management of prolonged air leak. Clin Chest Med. 2010;31:127–33. Table of Contents.

    Article  PubMed  Google Scholar 

  79. Wiaterek G, Lee H, Malhotra R, Shepherd W. Bronchoscopic blood patch for treatment of persistent alveolar-pleural fistula. J Bronchol Interv Pulmonol. 2013;20:171–4.

    Article  Google Scholar 

  80. Ruttenstock E, Saxena AK, Hollwarth ME. Closure of bronchopleural fistula with porcine dermal collagen and fibrin glue in an infant. Ann Thorac Surg. 2012;94:659–60.

    Article  PubMed  Google Scholar 

  81. Heslet L, Nielsen JD, Levi M, Sengelov H, Johansson PI. Successful pulmonary administration of activated recombinant factor VII in diffuse alveolar hemorrhage. Crit Care. 2006; 10:R177.

    Article  PubMed Central  PubMed  Google Scholar 

  82. Estella A, Jareno A, Perez-Bello Fontaina L. Intrapulmonary administration of recombinant activated factor VII in diffuse alveolar haemorrhage: a report of two case stories. Cases J. 2008;1:150.

    Article  PubMed Central  PubMed  Google Scholar 

  83. Colin AA, Shafieian M, Andreansky M. Bronchoscopic instillation of activated recombinant factor VII to treat diffuse alveolar hemorrhage in a child. Pediatr Pulmonol. 2010;45(4):411.

    Google Scholar 

  84. Ali-Dinar T, Colin AA, Andreansky M, Reiter L. Direct pulmonary instillation of recombinant factor VII (rFVIIa) for treatment of diffuse alveolar hemorrhage (DAH) in a 2 year old: the youngest pediatric case reported. Paediatr Respir Rev. 2013;14 Suppl 2:S77.

    Google Scholar 

  85. Heslet L, Nielsen JD, Nepper-Christensen S. Local pulmonary administration of factor VIIa (rFVIIa) in diffuse alveolar hemorrhage (DAH) – a review of a new treatment paradigm. Biologics. 2012;6:37–46.

    CAS  PubMed Central  PubMed  Google Scholar 

  86. Bramson RT, Sherman JM, Blickman JG. Pediatric bronchography performed through the flexible bronchoscope. Eur J Radiol. 1993;16:158–61.

    Article  CAS  PubMed  Google Scholar 

  87. Quintero RA, Kontopoulos E, Reiter J, Pedreira WL, Colin AA. Fetal bronchoscopy: its successful use in a case of extralobar pulmonary sequestration. J Matern Fetal Neonatal Med. 2012;25:2354–8.

    Article  PubMed  Google Scholar 

  88. Langston C. New concepts in the pathology of congenital lung malformations. Semin Pediatr Surg. 2003;12:17–37.

    Article  PubMed  Google Scholar 

  89. Riedlinger WF, Vargas SO, Jennings RW, et al. Bronchial atresia is common to extralobar sequestration, intralobar sequestration, congenital cystic adenomatoid malformation, and lobar emphysema. Pediatr Dev Pathol. 2006;9:361–73.

    Article  PubMed  Google Scholar 

  90. Peranteau WH, Merchant AM, Hedrick HL, et al. Prenatal course and postnatal management of peripheral bronchial atresia: association with congenital cystic adenomatoid malformation of the lung. Fetal Diagn Ther. 2008;24:190–6.

    Article  PubMed  Google Scholar 

  91. Reiter J, Colin AA, Kontopoulos EV, Shahzeidi S, Quintero RA. Fetal bronchoscopy for treatment of congenital pulmonary anomalies. Eur Respir J. 2013;42 Suppl 57:1062s.

    Google Scholar 

  92. Rada AG. Girl who had surgery to correct bronchial atresia in utero is healthy. BMJ. 2012;344:e2193.

    Article  Google Scholar 

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Colin, A.A., Reiter, J., Rossi, G.A., Quizon, A. (2015). Understanding Interventional Bronchoscopy. In: Davis, S., Eber, E., Koumbourlis, A. (eds) Diagnostic Tests in Pediatric Pulmonology. Respiratory Medicine. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1801-0_3

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