Skip to main content
SpringerLink
Log in

Optical Coherence Tomography for the Middle and Inner Ear

  • Chapter
  • First Online:
Biomedical Optics in Otorhinolaryngology

  • 966 Accesses

Abstract

Imaging for the middle and inner ear can be challenging, as conventional computed tomography and magnetic resonance imaging show limited resolution in time and space. Although relatively few studies exist on optical coherence tomography in this field, in vitro and in vivo, it has been shown that morphological data concerning middle ear structures and pathology such as biofilm can be identified with resolution in the range of few μm. In addition, image acquisition is now fast enough to assess sound transmission of middle ear ossicles, as well as capillary blood flow within the cochlea in real time. Thus, OCT is a powerful new tool for the clinician as well as for the researcher in otology, opening new horizons for office-based diagnosis and the understanding of middle and inner ear function.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Pitris C, Saunders KT, Fujimoto JG, Brezinski ME. High-resolution imaging of the middle ear with optical coherence tomography: a feasibility study. Arch Otolaryngol Head Neck Surg. 2001;127:637–42.

    Article  CAS  PubMed  Google Scholar 

  2. Just T, Lankenau E, Hüttmann G, Pau HW. Intraoperative application of optical coherence-tomography (OCT) for visualization of the oval window niche. Laryngorhinootologie. 2009;88:168–73.

    Article  CAS  PubMed  Google Scholar 

  3. Just T, Lankenau E, Hüttmann G, Pau HW. Optical coherence tomography of the oval window niche. J Laryngol Otol. 2009;123:603–8.

    Article  CAS  PubMed  Google Scholar 

  4. Just T, Lankenau E, Hüttmann G, Pau HW. Optical coherence tomography in middle ear surgery. HNO. 2009;57:421–7.

    Article  CAS  PubMed  Google Scholar 

  5. Subhash HM, Davila V, Sun H, Nguyen-Huynh AT, Shi X, Nuttall AL, Wang RK. Volumetric in vivo imaging of microvascular perfusion within the intact cochlea in mice using ultra-high sensitive optical microangiography. IEEE Trans Med Imaging. 2011;30:224–30.

    Article  PubMed  Google Scholar 

  6. Subhash HM, Nguyen-Huynh A, Wang RK, Jacques SL, Choudhury N, Nuttall AL. Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry. J Biomed Opt. 2012;17:060505.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Cho NH, Jang JH, Jung W, Kim J. In vivo imaging of middle-ear and inner-ear microstructures of a mouse guided by SD-OCT combined with a surgical microscope. Opt Express. 2014;22(8):8985–95.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Chang EW, Cheng JT, Röösli C, Kobler JB, Rosowski JJ, Yun SH. Simultaneous 3D imaging of sound-induced motions of the tympanic membrane and middle ear ossicles. Hear Res. 2013;304:49–56. doi:10.1016/j.heares.2013.06.006.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Burkhardt A, Kirsten L, Bornitz M, Zahnert T, Koch E. Investigation of the human tympanic membrane oscillation ex vivo by Doppler optical coherence tomography. J Biophotonics. 2014;7:434–41.

    Article  CAS  PubMed  Google Scholar 

  10. Heermann R, Hauger C, Issing PR, Lenarz T. Application of optical coherence tomography (OCT) in middle ear surgery. Laryngorhinoot-ologie. 2002;81:400–5.

    Google Scholar 

  11. Djalilian HR, Ridgway J, Tam M, Sepehr A, Chen Z, Wong BJ. Imaging the human tympanic membrane using optical coherence tomography in vivo. Otol Neurotol. 2008;29:1091–4.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Djalilian HR, Rubinstein M, Wu EC, Naemi K, Zardouz S, Karimi K, Wong BJ. Optical coherence tomography of cholesteatoma. Otol Neurotol. 2010;31:932–5.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Nguyen CT, Jung W, Kim J, Chaney EJ, Novak M, Stewart CN, Boppart SA. Noninvasive in vivo optical detection of biofilm in the human middle ear. Proc Natl Acad Sci USA. 2012;109:9529–34.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Nguyen CT, Robinson SR, Jung W, Novak MA, Boppart SA, Allen JB. Investigation of bacterial biofilm in the human middle ear using optical coherence tomography and acoustic measurements. Hear Res. 2013;301:193–200.

    Article  PubMed  PubMed Central  Google Scholar 

  15. McCaughey RG, Sun H, Rothholtz VS, Juhasz T, Wong BJ. Femtosecond laser ablation of the stapes. J Biomed Opt. 2009;14:024040.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Just T, Specht O, Ovari A, Langnau E, Schmidt W, Pau HW. Thermographic investigations during stapedotomy using a CO2 laser. Laryngorhinootologie. 2010;89:549–55.

    Article  CAS  PubMed  Google Scholar 

  17. Just T, Zehlicke T, Specht O, Sass W, Punke C, Schmidt W, Lankenau E, Behrend D, Pau HW. Detection of tympanic membrane movement using film patch with integrated strain gauge, assessed by optical coherence tomography: experimental study. J Laryngol Otol. 2011;125:467–73.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

This study was conducted jointly by Dipl.-Ing. Csaba Farkas and Dr.-Ing Achim Lenenbach, both Fraunhofer Institute for Laser Technology (ILT), Aachen, and the author. OCT system and equipment including custom-built scanner, micromanipulator, and CCD monitoring camera were built, adjusted, and operated by the ILT, while examination of healthy individuals as well as patients was performed by the author.

Author information

Authors and Affiliations

  1. Department of Otorhinolaryngology, Plastic Head and Neck Surgery, RWTH Aachen University Hospital, Aachen, Germany

    Justus Ilgner MD

  2. Department of Otorhinolaryngology, Head and Neck Surgery, KMG Klinikum Güstrow GmbH, Friedrich-Trendelenburg-Allee 1, Güstrow, 18273, Germany

    Tino Just MD

  3. Department of Medical Technology and Biophotonics, Fraunhofer Institute for Laser Technology, Aachen, Germany

    Csaba Farkas Dipl Ing & Achim Lenenbach Dr rer nat

  4. Department of Otorhinolaryngology, Plastic Surgery of Head and Neck, Universitätsklinikum Aachen, Aachen, Germany

    Martin Westhofen MD

Authors
  1. Justus Ilgner MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tino Just MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Csaba Farkas Dipl Ing
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Achim Lenenbach Dr rer nat
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Martin Westhofen MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tino Just MD .

Editor information

Editors and Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, Department of Biomedical Engineering, Division of Facial Plastic Surgery, The Beckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA

    Brian J.-F. Wong

  2. Department of Otorhinolaryngology, Plastic, Head and Neck Surgery, RWTH Aachen University Hospital, Aachen, Germany

    Justus Ilgner

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer Science+Business Media New York

About this chapter

Cite this chapter

Ilgner, J., Just, T., Farkas, C., Lenenbach, A., Westhofen, M. (2016). Optical Coherence Tomography for the Middle and Inner Ear. In: Wong, BF., Ilgner, J. (eds) Biomedical Optics in Otorhinolaryngology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1758-7_33

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1758-7_33

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1757-0

  • Online ISBN: 978-1-4939-1758-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation