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Photodynamic Therapy of Oropharyngeal Malignancies

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Abstract

Treating recurrent oropharyngeal malignancies poses a challenge. In many instances a conventional treatment such as surgery or radiation treatment is either not possible or would cause unacceptable morbidity. Photodynamic therapy could be an alternative treatment. The patients should be carefully assessed to confirm local disease and technical feasibility. While superficial tumors can be treated with light application to the surface, deeper lesions require interstitial light delivery strategies. In this chapter, details of different treatment strategies are described. There are a limited number of publications, especially about interstitial light delivery strategies. Our initial experiences are encouraging; however, the technique needs refinement and further research.

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Author information

Authors and Affiliations

  1. Department of Head and Neck Surgery and Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, Amsterdam, 1066CX, The Netherlands

    M. Barış Karakullukcu MD, PhD

Authors
  1. M. Barış Karakullukcu MD, PhD
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Correspondence to M. Barış Karakullukcu MD, PhD .

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Editors and Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, Department of Biomedical Engineering, Division of Facial Plastic Surgery, The Beckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA

    Brian J.-F. Wong

  2. Department of Otorhinolaryngology, Plastic, Head and Neck Surgery, RWTH Aachen University Hospital, Aachen, Germany

    Justus Ilgner

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Karakullukcu, M.B. (2016). Photodynamic Therapy of Oropharyngeal Malignancies. In: Wong, BF., Ilgner, J. (eds) Biomedical Optics in Otorhinolaryngology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1758-7_22

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  • DOI: https://doi.org/10.1007/978-1-4939-1758-7_22

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  • Online ISBN: 978-1-4939-1758-7

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