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Malignant Renal Tumors

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Pediatric Malignancies: Pathology and Imaging

Abstract

The majority of pediatric renal tumors are Wilms’ tumors. Of particular concern are those renal neoplasms carrying malignant potential. These entities are given particular attention in this chapter. Universally, partial and radical nephrectomies are used to treat both benign and malignant neoplasms. Chemotherapies have improved the prognosis of many malignant renal tumors, such as Wilms, but others, especially those carrying INI-1 mutations, remain difficult to treat and have high mortality rates. More molecular and genetic research is needed to fully understand and successfully treat this subset of childhood tumor.

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Authors and Affiliations

  1. Radiology, St. Louis Children’s Hospital, Washington University School of Medicine – MIR, 510 S. Kingshighway, 8131, St. Louis, MO, 63110, USA

    Geetika Khanna M.D., M.S.

  2. Department of Pathology and Pediatrics, Emory University School of Medicine, Pediatric Pathologist, Children’s Healthcare of Atlanta, 1405 Clifton Road, Atlanta, GA, 30322, USA

    Bahig M. Shehata, Mina M. Naguib & Jenny Lin

Authors
  1. Bahig M. Shehata
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  2. Mina M. Naguib
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  3. Jenny Lin
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  4. Geetika Khanna M.D., M.S.
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Correspondence to Geetika Khanna M.D., M.S. .

Editor information

Editors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, University of Southern California, Los Angeles, California, USA

    David M. Parham

  2. Associate Professor of Pathology and Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

    Joseph D. Khoury

  3. Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

    M. Beth McCarville

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Shehata, B.M., Naguib, M.M., Lin, J., Khanna, G. (2015). Malignant Renal Tumors. In: Parham, D., Khoury, J., McCarville, M. (eds) Pediatric Malignancies: Pathology and Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1729-7_10

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