Skip to main content

Skeletal System

  • Chapter
  • First Online:
Well-Differentiated Malignancies

Part of the book series: Current Clinical Pathology ((CCPATH))

  • 796 Accesses

Abstract

During the embryonal stage, two types of ossification mechanism are involved. In the endochondral process, ossification starts on the framework of prefabricated chondroid tissue. This type of ossification also forms the basis for bone elongation and callus formation. The osteogenic and chondrogenic processes are so intricately connected that both osteoid and chondroid components are often seen in osteoid forming and chondroid tumors, benign or malignant.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Rosenberg AE, Roth SI. Chapter 4. Bone. In: Mills SE, editor. Histology for pathologists. Philadelphia: Lippincott Williams & Wilkins/Wolters Kluwer; 2007. p. 75–96.

    Google Scholar 

  2. Bianco P, Sacchetti B, Riminucci M. Osteoprogenitors and the hematopoietic microenvironment. Best Pract Res Clin Haematol. 2011;24(1):37–47.

    Article  PubMed  CAS  Google Scholar 

  3. Schaffler MB, et al. Osteocytes: master orchestrators of bone. Calcif Tissue Int. 2014;94(1):5–24.

    Google Scholar 

  4. Toledo SR et al. Bone deposition, bone resorption, and osteosarcoma. J Orthop Res. 2010;28(9):1142–8.

    Article  PubMed  Google Scholar 

  5. Power PF et al. ETV5 as a regulator of matrix metalloproteinase 2 in human chondrosarcoma. J Orthop Res. 2012;31(3):493–501.

    Article  PubMed  Google Scholar 

  6. Unni KK. Chapter 5. Bone forming lesions. In: Tumors of the bones and joints. Silver Spring: ARP press; 2005. p. 119–92.

    Google Scholar 

  7. Unni KK. Chapter 4. Cartilaginous lesions. In: Tumors of the bones and joints. Silver Spring: ARP press; 2005. p. 37–118.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Sun, X. (2015). Skeletal System. In: Well-Differentiated Malignancies. Current Clinical Pathology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1692-4_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1692-4_3

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1691-7

  • Online ISBN: 978-1-4939-1692-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics