Skip to main content

45 Long-Term Mortality After Bariatric Surgery

  • Chapter
  • First Online:
Minimally Invasive Bariatric Surgery
  • 1612 Accesses

Abstract

Bariatric surgery results in significant weight loss and improvement in obesity-related comorbidities. These benefits ultimately lead to improved health and increased survival. The current data show that the long-term mortality after adjustable gastric banding (AGB) decreased from a range of 2.5–10.6 % in nonsurgical controls to a range of 0–3.7 % in surgical patients. Vertical sleeve gastrectomy (VSG) also demonstrated low long-term mortality, although at relatively shorter term. Biliopancreatic diversion (BPD) has a reported a mortality of 0.2–8 % at mean follow-up of 2–12 years. Long-term mortality following Roux-en-Y gastric bypass (RYBG) ranged from 1.8 to 9 % and represented a significant reduction compared to mortality in obese individuals who did not undergo surgery (4.1 to 28 %). In studies which included multiple operations, the overall long-term mortality rate for bariatric surgery ranged from 0.68 to 5 % and was significantly lower than control mortality of 6.17–6.3 % at 5–11 years after surgery. Current data seem to clearly support that bariatric surgery significantly reduces obesity-related mortality.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

AGB:

Adjustable gastric banding

BMI:

Body mass index

CVD:

Cardiovascular disease

DM:

Type II diabetes mellitus

DYS:

Dyslipidemia

HTN:

Hypertension

RYGB:

Roux-en-Y gastric bypass

VBG:

Vertical banded gastroplasty

VSG:

Vertical sleeve gastrectomy

References

  1. Fact Sheet N 311. Obesity and overweight, World Health Organization May 2012. http://www.who.int/mediacentre/factsheets/fs311/en/index.html

  2. Finkelstein EA, Khavjou OA, Thompson H, Trogdon JG, Pan L, Sherry B, et al. Obesity and severe obesity forecasts through 2030. Am J Prev Med. 2012;42(6):563–70.

    Article  PubMed  Google Scholar 

  3. Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999–2010. JAMA. 2012;307(5):491–7.

    Article  PubMed  Google Scholar 

  4. Terranova L, Busetto L, Vestri A, Zappa MA. Bariatric surgery: cost-effectiveness and budget impact. Obes Surg. 2012;22(4):646–53.

    Article  PubMed  Google Scholar 

  5. Thorpe KE. The future cost of obesity: national and state estimates of the impact of obesity on direct health care expenses. 2009.

    Google Scholar 

  6. Sturm R. The effects of obesity, smoking, and drinking on medical problems and costs. Health Aff (Millwood). 2002;21(2):245–53.

    Article  Google Scholar 

  7. Weiss AJ, Elixhauser A. Obesity-related hospitalizations, 2004 versus 2009: statistical brief #137. Healthcare cost and utilization project (HCUP) statistical briefs. Rockville. 2006.

    Google Scholar 

  8. Kaplan LM. Body weight regulation and obesity. J Gastrointest Surg. 2003;7(4):443–51.

    Article  PubMed  Google Scholar 

  9. Schienkiewitz A, Mensink GB, Scheidt-Nave C. Comorbidity of overweight and obesity in a nationally representative sample of German adults aged 18–79 years. BMC Public Health. 2012;12(1):658.

    Article  PubMed Central  PubMed  Google Scholar 

  10. Eheman C, Henley SJ, Ballard-Barbash R, Jacobs EJ, Schymura MJ, Noone AM, et al. Annual Report to the Nation on the status of cancer, 1975–2008, featuring cancers associated with excess weight and lack of sufficient physical activity. Cancer. 2012;118(9):2338–66.

    Article  PubMed  Google Scholar 

  11. Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197–209.

    Article  PubMed  Google Scholar 

  12. Kockanek K, Xu J, Murphy S, Minino A, Kung H. National vital statistics report: deaths: final data for 2009. In: Services U.S.D.o.H.a.H., editor. December 2011.

    Google Scholar 

  13. Barkoudah E, Skali H, Uno H, Solomon SD, Pfeffer MA. Mortality rates in trials of subjects with type 2 diabetes. J Am Heart Assoc. 2012;1(1):8–15.

    Article  PubMed Central  PubMed  Google Scholar 

  14. Batsis JA, Romero-Corral A, Collazo-Clavell ML, Sarr MG, Somers VK, Lopez-Jimenez F. Effect of bariatric surgery on the metabolic syndrome: a population-based, long-term controlled study. Mayo Clin Proc. 2008;83(8):897–907.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Allison DB, Fontaine KR, Manson JE, Stevens J, VanItallie TB. Annual deaths attributable to obesity in the United States. JAMA. 1999;282(16):1530–8.

    Article  CAS  PubMed  Google Scholar 

  16. Flegal KM, Graubard BI, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005;293(15):1861–7.

    Article  CAS  PubMed  Google Scholar 

  17. Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009;373(9669):1083–96.

    Article  PubMed  Google Scholar 

  18. Nguyen NT, Root J, Zainabadi K, Sabio A, Chalifoux S, Stevens CM, et al. Accelerated growth of bariatric surgery with the introduction of minimally invasive surgery. Arch Surg. 2005;140(12):1198–202; discussion 203.

    Article  PubMed  Google Scholar 

  19. Garb J, Welch G, Zagarins S, Kuhn J, Romanelli J. Bariatric surgery for the treatment of morbid obesity: a meta-analysis of weight loss outcomes for laparoscopic adjustable gastric banding and laparoscopic gastric bypass. Obes Surg. 2009;19(10):1447–55.

    Article  PubMed  Google Scholar 

  20. Weller WE, Rosati C. Comparing outcomes of laparoscopic versus open bariatric surgery. Ann Surg. 2008;248(1):10–5.

    Article  PubMed  Google Scholar 

  21. Dumon KR, Murayama KM. Bariatric surgery outcomes. Surg Clin North Am. 2011;91(6):1313–38.

    Article  PubMed  Google Scholar 

  22. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724–37.

    Article  CAS  PubMed  Google Scholar 

  23. Ali MR, Maguire MB, Wolfe BM. Assessment of obesity-related comorbidities: a novel scheme for evaluating bariatric surgical patients. J Am Coll Surg. 2006;202(1):70–7.

    Article  PubMed  Google Scholar 

  24. Smith MD, Patterson E, Wahed AS, Belle SH, Berk PD, Courcoulas AP, et al. Thirty-day mortality after bariatric surgery: independently adjudicated causes of death in the longitudinal assessment of bariatric surgery. Obes Surg. 2011;21(11):1687–92.

    Article  PubMed Central  PubMed  Google Scholar 

  25. Dolan K, Finch R, Fielding G. Laparoscopic gastric banding and crural repair in the obese patient with a hiatal hernia. Obes Surg. 2003;13(5):772–5.

    Article  PubMed  Google Scholar 

  26. Dargent J. Pouch dilatation and slippage after adjustable gastric banding: is it still an issue? Obes Surg. 2003;13(1):111–5.

    Article  PubMed  Google Scholar 

  27. Sivagnanam P, Rhodes M. The importance of follow-up and distance from centre in weight loss after laparoscopic adjustable gastric banding. Surg Endosc. 2010;24(10):2432–8.

    Article  PubMed  Google Scholar 

  28. Peeters A, O’Brien PE, Laurie C, Anderson M, Wolfe R, Flum D, et al. Substantial intentional weight loss and mortality in the severely obese. Ann Surg. 2007;246(6):1028–33.

    Article  PubMed  Google Scholar 

  29. O’Brien PE, Macdonald L, Anderson M, Brennan L, Brown WA. Long-term outcomes after bariatric surgery: fifteen-year follow-up of adjustable gastric banding and a systematic review of the bariatric surgical literature. Ann Surg. 2013;257(1):87–94.

    Article  PubMed  Google Scholar 

  30. Busetto L, Mirabelli D, Petroni ML, Mazza M, Favretti F, Segato G, et al. Comparative long-term mortality after laparoscopic adjustable gastric banding versus nonsurgical controls. Surg Obes Relat Dis. 2007;3(5):496–502.

    Article  PubMed  Google Scholar 

  31. Favretti F, Segato G, Ashton D, Busetto L, De Luca M, Mazza M, et al. Laparoscopic adjustable gastric banding in 1,791 consecutive obese patients: 12-year results. Obes Surg. 2007;17(2):168–75.

    Article  PubMed  Google Scholar 

  32. Miller K, Pump A, Hell E. Vertical banded gastroplasty versus adjustable gastric banding: prospective long-term follow-up study. Surg Obes Relat Dis. 2007;3(1):84–90.

    Article  PubMed  Google Scholar 

  33. Stroh C, Hohmann U, Schramm H, Meyer F, Manger T. Fourteen-year long-term results after gastric banding. J Obes. 2011;2011:128451.

    Article  PubMed Central  PubMed  Google Scholar 

  34. Himpens J, Cadiere GB, Bazi M, Vouche M, Cadiere B, Dapri G. Long-term outcomes of laparoscopic adjustable gastric banding. Arch Surg. 2011;146(7):802–7.

    Article  PubMed  Google Scholar 

  35. Cottam D, Qureshi FG, Mattar SG, Sharma S, Holover S, Bonanomi G, et al. Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc. 2006;20(6):859–63.

    Article  CAS  PubMed  Google Scholar 

  36. Boza C, Gamboa C, Salinas J, Achurra P, Vega A, Perez G. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case-control study and 3 years of follow-up. Surg Obes Relat Dis. 2012;8(3):243–9.

    Article  PubMed  Google Scholar 

  37. Sarela AI, Dexter SP, O’Kane M, Menon A, McMahon MJ. Long-term follow-up after laparoscopic sleeve gastrectomy: 8–9-year results. Surg Obes Relat Dis. 2012;8(6):679–84.

    Article  PubMed  Google Scholar 

  38. Eid GM, Brethauer S, Mattar SG, Titchner RL, Gourash W, Schauer PR. Laparoscopic sleeve gastrectomy for super obese patients: forty-eight percent excess weight loss after 6 to 8 years with 93 % follow-up. Ann Surg. 2012;256(2):262–5.

    Article  PubMed  Google Scholar 

  39. Guedea ME, Arribas del Amo D, Solanas JA, Marco CA, Bernado AJ, Rodrigo MA, et al. Results of biliopancreatic diversion after five years. Obes Surg. 2004;14(6):766–72.

    Article  PubMed  Google Scholar 

  40. Marceau P, Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, et al. Duodenal switch: long-term results. Obes Surg. 2007;17(11):1421–30.

    Article  PubMed  Google Scholar 

  41. Hess D, Hess D, Oakley R. The biliopancreatic diversion with the duodenal switch: results beyond 10 years. Obes Surg. 2005;15(3):408–16.

    Article  PubMed  Google Scholar 

  42. Crea N, Pata G, Di Betta E, Greco F, Casella C, Vilardi A, et al. Long-term results of biliopancreatic diversion with or without gastric preservation for morbid obesity. Obes Surg. 2011;21(2):139–45.

    Article  PubMed  Google Scholar 

  43. Biertho L, Lebel S, Marceau S, Hould FS, Lescelleur O, Moustarah F, et al. Perioperative complications in a consecutive series of 1000 duodenal switches. Surg Obes Relat Dis. 2013;9:63–8.

    Article  PubMed  Google Scholar 

  44. Pata G, Crea N, Di Betta E, Bruni O, Vassallo C, Mittempergher F. Biliopancreatic diversion with transient gastroplasty and duodenal switch: long-term results of a multicentric study. Surgery. 2013;153:413–22.

    Article  PubMed  Google Scholar 

  45. Topart P, Becouarn G, Salle A. Five-year follow-up after biliopancreatic diversion with duodenal switch. Surg Obes Relat Dis. 2011;7(2):199–205.

    Article  PubMed  Google Scholar 

  46. Dorman RB, Rasmus NF, Al-Haddad BJ, Serrot FJ, Slusarek BM, Sampson BK, et al. Benefits and complications of the duodenal switch/biliopancreatic diversion compared to the Roux-en-Y gastric bypass. Surgery. 2012;152(4):758–65; discussion 65-7.

    Article  PubMed  Google Scholar 

  47. MacDonald Jr KG, Long SD, Swanson MS, Brown BM, Morris P, Dohm GL, et al. The gastric bypass operation reduces the progression and mortality of non-insulin-dependent diabetes mellitus. J Gastrointest Surg. 1997;1(3):213–20; discussion 20.

    Article  PubMed  Google Scholar 

  48. Flum DR, Dellinger EP. Impact of gastric bypass operation on survival: a population-based analysis. J Am Coll Surg. 2004;199(4):543–51.

    Article  PubMed  Google Scholar 

  49. Sugerman HJ, Wolfe LG, Sica DA, Clore JN. Diabetes and hypertension in severe obesity and effects of gastric bypass-induced weight loss. Ann Surg. 2003;237(6):751–6. discussion 7-8.

    PubMed Central  PubMed  Google Scholar 

  50. Adams TD, Gress RE, Smith SC, Halverson RC, Simper SC, Rosamond WD, et al. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007;357(8):753–61.

    Article  CAS  PubMed  Google Scholar 

  51. Suter M, Donadini A, Romy S, Demartines N, Giusti V. Laparoscopic Roux-en-Y gastric bypass: significant long-term weight loss, improvement of obesity-related comorbidities and quality of life. Ann Surg. 2011;254(2):267–73.

    Article  PubMed  Google Scholar 

  52. Mason EE, Renquist KE, Jiang D. Perioperative risks and safety of surgery for severe obesity. Am J Clin Nutr. 1992;55(2 Suppl):573S–6.

    CAS  PubMed  Google Scholar 

  53. Livingston EH, Huerta S, Arthur D, Lee S, De Shields S, Heber D. Male gender is a predictor of morbidity and age a predictor of mortality for patients undergoing gastric bypass surgery. Ann Surg. 2002;236(5):576–82.

    Article  PubMed Central  PubMed  Google Scholar 

  54. Maciejewski ML, Livingston EH, Smith VA, Kavee AL, Kahwati LC, Henderson WG, et al. Survival among high-risk patients after bariatric surgery. JAMA. 2011;305(23):2419–26.

    Article  CAS  PubMed  Google Scholar 

  55. Sowemimo OA, Yood SM, Courtney J, Moore J, Huang M, Ross R, et al. Natural history of morbid obesity without surgical intervention. Surg Obes Relat Dis. 2007;3(1):73–7; discussion 7.

    Article  PubMed  Google Scholar 

  56. Higa K, Ho T, Tercero F, Yunus T, Boone KB. Laparoscopic Roux-en-Y gastric bypass: 10-year follow-up. Surg Obes Relat Dis. 2011;7(4):516–25.

    Article  PubMed  Google Scholar 

  57. Christou NV, Sampalis JS, Liberman M, Look D, Auger S, McLean AP, et al. Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients. Ann Surg. 2004;240(3):416–23; discussion 23-4.

    Article  PubMed Central  PubMed  Google Scholar 

  58. Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52.

    Article  PubMed  Google Scholar 

  59. Pontiroli AE, Morabito A. Long-term prevention of mortality in morbid obesity through bariatric surgery: a systematic review and meta-analysis of trials performed with gastric banding and gastric bypass. Ann Surg. 2011;253(3):484–7.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohamed R. Ali .

Editor information

Editors and Affiliations

Review Questions and Answers

Review Questions and Answers

  1. 1.

    According to the World Health Organization, what chronic condition is now a major cause of mortality in the majority of countries?

    1. A.

      Malnutrition

    2. B.

      Tuberculosis

    3. C.

      Obesity

    4. D.

      Pesticides

    • Answer: C

  2. 2.

    Which of the following causes of mortality is MOST reduced by Roux-en-Y gastric bypass?

    1. A.

      Diabetes

    2. B.

      Cancer

    3. C.

      Cardiovascular

    4. D.

      All-cause mortality

    • Answer: A

  3. 3.

    What is the proposed mechanism by which bariatric surgery reduces long-term mortality?

    1. A.

      Weight loss

    2. B.

      Improvement in comorbidities

    3. C.

      Decrease in cancer incidence

    4. D.

      Multifactorial

    5. E.

      All of the above

    • Answer: E

  4. 4.

    Which of the following is the greatest predictor of overall mortality following bariatric surgery?

    1. A.

      Previous surgery

    2. B.

      History of myocardial infarction

    3. C.

      BMI > 50 kg/m2

    4. D.

      Type II diabetes mellitus

    • Answer: B

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Carr, A.D., Ali, M.R. (2015). 45 Long-Term Mortality After Bariatric Surgery. In: Brethauer, S., Schauer, P., Schirmer, B. (eds) Minimally Invasive Bariatric Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1637-5_45

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1637-5_45

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1636-8

  • Online ISBN: 978-1-4939-1637-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics