Abstract
Vasculitis is defined by the presence of inflammation within the blood vessel wall, which can result in vascular aneurysms or conversely vessel stenosis or occlusion. Vasculitis can occur secondary to a wide range of underlying causes or a primary vasculitic disease for which the underlying etiology has not yet been identified. Although immunosuppressive therapy represents the foundation of treatment for active vasculitis, vascular surgeons play an important role in the management of emergent or elective complications of vasculitis affecting the medium to large sized arteries. Polyarteritis nodosa, giant cell arteritis, and Takayasu arteritis are the primary vasculitic diseases that most prominently affect these vessels and represent the vasculitides most commonly encountered by vascular surgeons.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Jennette JC, Falk RJ, Bacon PA, et al. 2012 revised international Chapel Hill consensus conference nomenclature of vasculitides. Arthritis Rheum. 2013;65(1):1–11.
Pagnoux C, Seror R, Henegar C, et al. Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database. Arthritis Rheum. 2010;62(2):616–26.
Levine SM, Hellmann DB, Stone JH. Gastrointestinal involvement in polyarteritis nodosa (1986-2000): presentation and outcomes in 24 patients. Am J Med. 2002;112(5):386–91.
Pagnoux C, Mahr A, Cohen P, et al. Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides: analysis of 62 patients with polyarteritis nodosa, microscopic polyangiitis, Wegener granulomatosis, Churg-Strauss syndrome, or rheumatoid arthritis-associated vasculitis. Medicine (Baltimore). 2005;84(2):115–28.
Gayraud M, Guillevin L, le Toumelin P, et al. Long-term followup of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: analysis of four prospective trials including 278 patients. Arthritis Rheum. 2001;44(3):666–75.
Ribi C, Cohen P, Pagnoux C, et al. Treatment of polyarteritis nodosa and microscopic polyangiitis without poor-prognosis factors: a prospective randomized study of one hundred twenty-four patients. Arthritis Rheum. 2010;62(4):1186–97.
Guillevin L, Mahr A, Callard P, et al. Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients. Medicine (Baltimore). 2005;84(5):313–22.
Hernández-Rodríguez J, Molloy ES, Hoffman GS. Single-organ vasculitis. Curr Opin Rheumatol. 2008;20(1):40–6.
Parent BA, Cho SW, Buck DG, et al. Spontaneous rupture of hepatic artery aneurysm associated with polyarteritis nodosa. Am Surg. 2010;76(12):1416–9.
Stambo GW, Guiney MJ, Cannella XF, et al. Coil embolization of multiple hepatic artery aneurysms in a patient with undiagnosed polyarteritis nodosa. J Vasc Surg. 2004;39(5):1122–4.
Salvarani C, Pipitone N, Versari A. Clinical features of polymyalgia rheumatica and giant cell arteritis. Nat Rev Rheumatol. 2012;8(9):509–21.
Bongartz T, Matteson EL. Large-vessel involvement in giant cell arteritis. Curr Opin Rheumatol. 2006;18(1):10–7.
Kermani TA, Warrington KJ, Crowson CS, et al. Large-vessel involvement in giant cell arteritis: a population-based cohort study of the incidence-trends and prognosis. Ann Rheum Dis. 2013;72(12):1989–94.
García-Martínez A, Arguis P, Prieto-González S, et al. Prospective long term follow-up of a cohort of patients with giant cell arteritis screened for aortic structural damage (aneurysm or dilatation). Ann Rheum Dis. 2013 Jul 19.
Schmidt WA, Kraft HE, Vorpahl K, et al. Color duplex ultrasonography in the diagnosis of temporal arteritis. N Engl J Med. 1997;337(19):1336–42.
Salvarani C, Silingardi M, Ghirarduzzi A, et al. Is duplex ultrasonography useful for the diagnosis of giant-cell arteritis? Ann Intern Med. 2002;137(4):232–8.
Aiello PD, Trautmann JC, McPhee TJ, et al. Visual prognosis in giant cell arteritis. Ophthalmology. 1993;100(4):550–5.
Nesher G, Berkun Y, Mates M, et al. Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis. Arthritis Rheum. 2004;50(4):1332–7.
Hoffman GS, Cid MC, Hellmann DB, Guillevin L, et al. A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritis. Arthritis Rheum. 2002;46(5):1309–18.
Hoffman GS, Cid MC, Rendt-Zagar KE, et al. Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis: a randomized trial. Ann Intern Med. 2007;146(9):621–30.
Rojo-Leyva F, Ratliff NB, Cosgrove 3rd DM, et al. Study of 52 patients with idiopathic aortitis from a cohort of 1,204 surgical cases. Arthritis Rheum. 2000;43(4):901–7.
Liang KP, Chowdhary VR, Michet CJ, et al. Noninfectious ascending aortitis: a case series of 64 patients. J Rheumatol. 2009;36(10):2290–7.
Albacker T, Svensson L. Cardiothoracic surgery for Takayasu’s arteritis and ginat cell arteritis. In: Hoffman GS, Weyand CM, Langford CA, Goronzy JJ, editors. Inflammatory diseases of blood vessels. 2nd ed. Oxford: Wiley-Blackwell; 2012.
Rajani RR, Kashyap VS. Peripheral vascular surgery for large vessel vasculitis. In: Hoffman GS, Weyand CM, Langford CA, Goronzy JJ, editors. Inflammatory diseases of blood vessels. 2nd ed. Oxford: Wiley-Blackwell; 2012.
Kerr GS, Hallahan CW, Giordano J, et al. Takayasu arteritis. Ann Intern Med. 1994;120:919–29.
Maksimowicz-McKinnon K, Clark TM, Hoffman GS. Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients. Arthritis Rheum. 2007;56:1000–9.
Tso E, Flamm SD, White RD, et al. Takayasu arteritis: utility and limitations of magnetic resonance imaging in diagnosis and treatment. Arthritis Rheum. 2002;46(6):1634–42.
de Souza AW, Machado NP, Pereira VM, et al. Antiplatelet therapy for the prevention of arterial ischemic events in Takayasu arteritis. Circ J. 2010;74:1236–41.
Hoffman GS, Leavitt RY, Kerr GS, et al. Treatment of glucocorticoid-resistant or relapsing Takayasu arteritis with methotrexate. Arthritis Rheum. 1994;37:578–82.
Molloy ES, Langford CA, Clark TM, et al. Anti-tumour necrosis factor therapy in patients with refractory Takayasu arteritis: long-term follow-up. Ann Rheum Dis. 2008;67:1567–9.
Liang P, Tan-Ong M, Hoffman GS. Takayasu’s arteritis: vascular interventions and outcomes. J Rheumatol. 2004;31:102–6.
Giordano JM, Leavitt RY, Hoffman GS, et al. Experience with surgical treatment for Takayasu’s disease. Surgery. 1991;109:252–8.
Kim YW, Kim DI, Park YJ, et al. Surgical bypass vs endovascular treatment for patients with supra-aortic arterial occlusive disease due to Takayasu arteritis. J Vasc Surg. 2012;55:693–700.
Saadoun D, Lambert M, Mirault T, et al. Retrospective analysis of surgery versus endovascular intervention in Takayasu arteritis: a multicenter experience. Circulation. 2012;125:813–9.
Qureshi MA, Martin Z, Greenberg RK. Endovascular management of patients with Takayasu arteritis: stents versus stent grafts. Semin Vasc Surg. 2011;24:44–52.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this chapter
Cite this chapter
Langford, C.A. (2014). Vasculitis. In: Shah, S., Clair, D. (eds) Cleveland Clinic Manual of Vascular Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1631-3_10
Download citation
DOI: https://doi.org/10.1007/978-1-4939-1631-3_10
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4939-1630-6
Online ISBN: 978-1-4939-1631-3
eBook Packages: MedicineMedicine (R0)